The American Society of Hematology has released new clinical practice guidelines for treating acute myeloid leukemia (AML) in older adults. The guidelines aim to provide personalized care by addressing patients' goals and wishes throughout their disease course.
A study published in The Lancet found that plaster casts are as effective as surgery in healing scaphoid waist fractures in the wrist. Patients who received a plaster cast showed similar outcomes to those who underwent surgery, with no significant difference in pain, function, or complications.
Researchers at the University of Pittsburgh and UCSF developed a non-invasive device that stimulates the vagus nerve to improve language learning. Participants showed significant improvements in distinguishing Mandarin tones, with some reaching peak performance twice as quickly as control participants.
Post-theatrical release piracy is connected to higher ticket sales due to increased word-of-mouth advertising. Movie studios should focus on preventing pirated copies from leaking online before release.
Scientists at NTU Singapore developed a synthetic peptide, CSM5-K5, that makes multidrug-resistant bacteria sensitive to antibiotics when used with traditional antibiotics. The peptide also kills resistant bacteria on its own, offering hope for combination treatment strategies.
A new study reveals racial disparities in high-cost proton radiotherapy for childhood cancer treatment, with Black and low-income children facing barriers to access. The research highlights the urgent need for equitable healthcare policies to ensure all children receive quality cancer care regardless of their race or socioeconomic status.
Researchers employed a gendered ecosystem services approach with Lozi communities to identify locally relevant strategies for sustainable agricultural development. The study found that agroecological intensification, such as multiple cropping and agroforestry, can restore and maintain ecosystem services in cultivated lands while reduci...
A recent study by Washington State University criminologist Kathryn DuBois found that women from small towns are most at risk of intimate partner violence, with a 27% higher likelihood of being victims compared to urban areas and 42% more likely than suburban women.
Researchers investigate how genetics influence rumen microbiome in cattle, seeking to identify host genomic markers for heritability. The study aims to manipulate microbiomes to enhance agricultural production and develop more sustainable cow-calf systems.
A team of researchers at Michigan Medicine developed a guide to help oncologists navigate difficult conversations with patients due to the pandemic. The guide provides three core communication strategies and examples of language that can be used to respond empathetically, addressing concerns around risk, delays, and changes in treatment.
Researchers have discovered a 99-million-year-old fossil of an ancient 'hell ant' that shows how it hunted its prey with deadly precision. The fossil, which is one of the oldest and most well-preserved ever found, reveals the mechanism behind the hell ant's unique mouthparts and headgear.
Researchers identified five blood biomarkers associated with increased odds of clinical deterioration and death in COVID-19 patients. Elevated levels of these biomarkers were linked to inflammation and bleeding disorders, increasing the risk of ICU admission, ventilatory support, and mortality.
A new method, nanoproteomics, captures and measures various forms of cardiac troponin I, a biomarker of heart damage. This effective test could one day provide doctors with a better ability to diagnose heart disease, the leading cause of death in the U.S.
Researchers develop a new class of materials that can seamlessly transfer a compound's bright fluorescence to a solid state, overcoming a long-standing barrier. The breakthrough has potential applications in solar energy harvesting, bioimaging, and lasers.
A new study published in Neurology found that people who experience a sudden drop in systolic blood pressure when standing up may be at higher risk of developing dementia years later. The study also showed that controlling these blood pressure drops could be a promising way to help preserve people's thinking and memory skills as they age.
A Marshall University researcher has been awarded a $444,000 grant to investigate the role of sodium pump signaling in fat cells and its potential as a treatment for uremic cardiomyopathy. The study aims to reveal more about oxidative stress and its impact on disease progression.
The Fukushima Dai-ichi Nuclear Power Plant's stored contaminated wastewater contains multiple radioactive isotopes with varying levels of risk. These include tritium, a relatively short-lived isotope, and other isotopes like carbon-14, cobalt-60, and strontium-90, which pose more complex hazards to humans and the environment.
A new alpha-radioimmunotherapy has proven effective in preventing tumor growth and increasing survival in multiple myeloma tumor-bearing mice. The therapy targets CD38 protein on tumoral cells and reduces unwanted radiation exposure on normal tissues.
A new study published in the Journal of the American College of Surgeons found that surgical delays for very early stage breast cancer patients did not impact overall survival. In fact, increased time to surgery was associated with a small increase in pathological upstaging, but no significant difference in survival rates.
Researchers challenge previous understanding of viscous bubble behavior, concluding that surface tension and dynamic stress are key drivers of bubble collapse. In viscous liquids, bubbles exhibit structural instability characterized by radial wrinkles around the periphery, a phenomenon previously attributed to gravity.
A new study found that HIV screening every three months compared to annually improves clinical outcomes and is cost-effective among high-risk YMSM in the US. The study also suggests that more frequent screening could lead to improved life expectancy and reduced HIV transmission among these men.
A new invasive species, Polydora websteri, has been found in the Wadden Sea, posing a significant threat to oyster farming and the ecosystem. The worm, likely originating from Asia, causes damage to oysters' shells, weakening them and making them vulnerable to predators.
Seabirds produce guano that serves as a fertilizer and contributes significantly to coastal and marine ecosystems. The researchers estimated the value of guano production at around $473 million per year, with nutrients deposited by seabirds worth an additional $1 billion annually.
Researchers created polyurethane foams from algae oil that meet commercial specifications for midsole shoes and footbeds of flip-flops. The biodegradable materials degraded after 16 weeks in compost and soil, showing potential for full recyclability and addressing the plastic waste problem.
Researchers discovered that unfair negative reviews can evoke consumer empathy, leading to increased purchase and patronage intentions. Firms can capitalize on these reviews by responding in a more personable manner and highlighting employee involvement.
Researchers propose a new hypothesis that the Y chromosome is protected from extinction by carrying 'executioner genes' that self-regulate and ensure successful sperm production. These genes, which regulate meiotic silencing, are toxic when activated at the wrong time, protecting the Y chromosome from loss.
Researchers create device to grow highly oxygen-intolerant bacteria in lab studies, revealing protective effects on human colon. They found that Faecalibacterium prausnitzii produces butyrate, which reduces inflammation and calms immune response.
Washington University researchers are developing a method to diagnose brain tumors without incisions, using ultrasonic energy to target tumors deep in the brain. The technique involves injecting microbubbles that rupture, releasing biomarkers from the tumor into the blood for testing with a blood draw, called a liquid biopsy.
Researchers discovered that REM sleep tunes eating behavior by reducing the activation of hypothalamic neurons in mice, indicating the importance of sleep quality in maintaining stable feeding habits. The study suggests a long-lasting effect on neuronal activity and feeding behavior.
Adranos has obtained significant funding from the US Army to develop and test its ALITEC solid rocket fuel in hypersonic research. The technology is expected to increase firing range for both traditional solid rocket motors and air-breathing systems, maximizing end-to-end system performance.
Researchers use CT scans to reveal that Tanystropheus lived in the ocean and had separate species of larger and smaller specimens. The study finds that the animals hunted different prey and coexisted without competing for resources.
A new study from the American College of Surgeons found that longer time to surgical treatment does not lower overall survival for women with early-stage breast cancer who underwent delayed operations before the pandemic. Patients who received neoadjuvant endocrine therapy also showed no decreased survival, according to the research.
Researchers at Tokyo Institute of Technology found that anthropogenic sources account for much of the missing source of OCS in the atmosphere. Their study provides better context for estimating global photosynthesis using OCS dynamics.
A new scoring system developed by NIH-funded researchers standardizes patient data to compare rates of severe maternal morbidity between different hospitals and groups of patients. The study aims to aid maternal health research and efforts to improve maternal health across the country.
A pre-clinical study led by Cincinnati Children's Hospital demonstrates that barasertib reverses fibroblast activation, stopping dangerous scar tissue build-up in lungs of IPF patients. The drug targets AURKB activity, slowing disease progress and improving lung function.
Researchers at LSU Health have discovered a crucial mechanism in brain cell communication that can help protect against stroke. They found that DHA, an omega-3 fatty acid, promotes the survival and integrity of neuronal cells by regulating key proteins involved in this communication.
A study by Brown University researchers found that inconsistent EPA regulations increase lead poisoning risk to over 35,000 US kids. The discrepancy puts children at nearly four times the risk of lead poisoning compared to homes with lower floor dust lead loadings.
A study led by Virginia Tech researchers explores the effects of mobile phones on Maasai women's lives, revealing that technology both empowers and hinders gender dynamics. The findings highlight the importance of understanding context-specific empowerment in rural communities.
The Arecibo Observatory successfully tracked asteroid 2020 NK1, determining its orbit and motion. The observations showed the asteroid poses no danger to Earth, with a closest approach in 2043. High-resolution images revealed an elongated shape and diameter of approximately 0.6 miles.
A new study from Oregon State University found that 77% of low- to moderate-income American households fall below the asset poverty threshold. This means they would not have enough financial assets to maintain at least poverty-level status for three months if their income were cut off.
Researchers identify granule cells as gatekeepers of the hippocampus, filtering out irrelevant information. These cells also appear to be involved in processing spatial information, converting grid cell activity into place cell activity.
Researchers identified a crown-shaped molecular pore in coronavirus replication compartments that may facilitate viral RNA export. This discovery offers a potential target for antiviral strategies against SARS-CoV-2 and other coronaviruses.
The COVID-19 pandemic has prompted oncology clinicians to prioritize cancer care, leveraging expertise from low-resource settings for guidance. Prioritization involves weighing the benefits and harms of different treatments, considering factors such as patient outcomes and healthcare resource availability.
The OU Health Sciences Center will expand a national program dedicated to suicide prevention with a $38 million five-year grant. The program aims to address workforce development, education, evidence-based prevention strategies, and public awareness to help people at risk of suicide. Key findings include increased focus on culturally r...
A study by Florida Atlantic University's Harbor Branch Oceanographic Institute found high concentrations of atrazine, DEP, NPE, and triclosan in stranded dolphins and whales. The study revealed significant variations in toxin and element concentrations based on animal demographic factors and geography.
A qualitative study proposes a practical communication guide to assuage the fear, anger and anxiety of cancer patients during the COVID-19 pandemic. The guide aims to improve patient care in oncology settings.
A new study found that adults experienced few changes in 'Big Five' personality traits during the early days of the COVID-19 pandemic. Neuroticism decreased slightly, while conscientiousness remained stable despite efforts to slow disease spread.
Researchers found that breast cancer diagnosis via diffusion-tensor imaging (DTI) was equivalent before and after gadolinium-based contrast agent administration. DTI parameters showed a statistically significant reduction in cancer lesions after contrast enhancement, leading to increased conspicuity for radiologists.
Researchers explored ways to ensure power supply in Spain, considering the scarcity of interconnection with neighboring countries. They found that flexible management of hydropower plants could alleviate supply shortages due to renewable energy's intermittency.
A novel connection between primordial organisms and complex life has been discovered, shedding light on the evolutionary origins of the cell division process. The study reveals a common regulatory mechanism in both archaea and eukaryotes, providing new insights into the history of eukaryotic cells.
A new study suggests electric cookers can sanitize N95 respirator masks through dry heat, preserving their filtration and fit. The method decontaminates the masks inside and out, enabling safe reuse of limited supplies.
Human hair is 50 times softer than steel yet can cause razor blade chipping and wear. Researchers found that the blade's microstructure and angle of approach to hair play key roles in initiating cracks.
A team from Lawson Health Research Institute is conducting a multi-centre clinical trial to study the use of inhaled sedatives as an alternative to intravenous sedatives for COVID-19 patients requiring ventilation. The trial aims to improve patient outcomes and address global shortages of IV sedatives.
Researchers at Texas A&M University are using advanced machine-learning analysis to reveal the evolution of cracks in rock and concrete. By combining data from multiple sources, including sound waves, electromagnetics, and pressure measurements, they aim to improve our understanding of crack damage and development.
The study found that patients following the ERAS protocol had significantly lower rates of opioid use at one, three, and six months after surgery compared to those receiving standard care. Additionally, the ERAS group experienced shorter hospital stays, fewer postoperative complications, and improved patient outcomes.
After a 5-year follow-up, bone-anchored leg prostheses show significant improvements in daily functioning, mobility, and quality of life for patients with above-knee amputations. Despite initial stoma problems, these prostheses lead to permanent benefits, including increased prosthesis use and improved health-related quality of life.
The study found that asymptomatic and symptomatic patients shed high levels of viral RNA. It quantifies the amount of virus present in these individuals.
Scientists discovered genes with decreased expression in individuals with Down syndrome, which may also protect people from developing solid tumors. These findings could lead to the development of gene-targeted therapies for both people with Down syndrome and the general population.
The Fukushima Daiichi Nuclear Power Plant disaster has left over 1,000 tanks containing contaminated water, with radioactive isotopes including tritium posing significant removal challenges. A full accounting of the remaining isotopes in each tank is needed to assess consequences of releasing them into the ocean.
A study by Tufts University researchers found that estrogen can have a disruptive effect on glucose metabolism in females, but not males, when a specific protein is absent. The study identified a key protein in the brain that mediates these effects and provides insight into the differences between men and women in their risk of diabetes.