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Science News Archive 2025 - Page 273


Page 273 of 574

Drug candidate successfully treats atherosclerosis, fatty liver disease in large mammals

Researchers successfully treated atherosclerosis and fatty liver disease using DT-109 in nonhuman primates, which has potential as a dual therapy for two common conditions. The compound reduced the formation of atherosclerotic plaques and stopped critical processes that lead to vascular calcification.

SourceMichigan Medicine - University of Michigan·JournalSignal Transduction and Targeted Therapy·TypeExperimental study·DateApr 23, 2025

Laboratory observation of USTC reveals key mechanism behind cosmic particle acceleration

Researchers at USTC directly observed ion acceleration through reflection off laser-generated magnetized collisionless shocks, demonstrating the role of shock drift acceleration. The experiment confirmed SDA's dominance over shock surfing acceleration, shedding light on cosmic particle origins and potential applications in fusion.

SourceUniversity of Science and Technology of China·JournalScience Advances·TypeExperimental study·DateApr 23, 2025

New porous crystal catalyst offers durable, efficient solution for clean hydrogen production

A new catalyst structure featuring mesoporous single-crystalline Co3O4 doped with atomically dispersed iridium (Ir) has been proposed as a potential pathway toward cost-effective hydrogen production. The material achieves efficient use of Ir while maintaining stability, reducing leaching during reaction.

SourceAdvanced Institute for Materials Research (AIMR), Tohoku University·JournalJournal of the American Chemical Society·DateApr 23, 2025

Rigid grant funding undermines community health centers’ ability to serve vulnerable New Yorkers

A new study by Columbia University Mailman School of Public Health researchers highlights the limitations of inflexible grant funding on community health centers (CHCs) in New York City. CHCs, which serve one in nine New Yorkers, operate on thin margins and struggle to provide comprehensive care due to restrictive state and local grants.

SourceColumbia University's Mailman School of Public Health·JournalBMC Health Services Research·TypeSurvey·DateApr 23, 2025

Neurodegenerative disease ALS: Cellular repair system could prevent protein aggregation

A team of researchers from Goethe University and Kiel University has discovered a way to prevent the formation of harmful protein aggregates in cultured cells. The study found that linking TDP-43 with SUMO prevents its aggregation, suggesting a potential new approach for treating ALS and other neurodegenerative diseases.

SourceGoethe University Frankfurt·JournalNature Chemical Biology·TypeExperimental study·DateApr 23, 2025

Varenicline for youth nicotine vaping cessation

A 12-week randomized clinical trial shows varenicline combined with behavioral counseling effectively increased vaping abstinence in youth who vape nicotine but do not regularly smoke tobacco. This study provides hope for a novel treatment approach to help combat the growing youth vaping epidemic.

SourceJAMA Network·JournalJAMA·DateApr 23, 2025

Singapore scientists unveil one of world’s largest long-read RNA sequencing datasets to advance disease research

A team of Singaporean scientists has released a comprehensive long-read RNA sequencing dataset, SG-NEx, to accelerate biomarker discovery and precision medicine. The dataset offers deeper biological insights into RNA complexity, enabling researchers to detect clinically relevant biomarkers and develop better treatments.

The antibiotic that takes the bite out of Lyme

Researchers identified piperacillin as an effective treatment for Lyme disease, which causes devastating symptoms in half a million individuals annually. The antibiotic works by targeting the bacteria's unique cell wall synthesis pattern, leading to its death without harming beneficial gut microbes.

SourceNorthwestern University·JournalScience Translational Medicine·DateApr 23, 2025

Review and prospects: application of spatio-temporal big data in transportation system resilience studies

A systematic review reveals that spatio-temporal big data applications in transportation resilience studies are most developed in quantitative assessment, but significant gaps remain in real-time monitoring and early warning systems. The study identifies the need for improved data integration frameworks and interdisciplinary cooperatio...

Aging reimagined: UT Health San Antonio study shifts focus from inevitable decline to optimizing resilience

Researchers discovered that individuals with robust immune resilience at midlife can gain a 15.5-year survival advantage due to their ability to counter disease drivers and maintain healthy aging. The study highlights the importance of salutogenesis, or promoting health and well-being from birth to approximately age 70.

SourceUniversity of Texas Health Science Center at San Antonio·JournalAging Cell·TypeData/statistical analysis·DateApr 23, 2025

Latest ACS cancer prevention and early detection report: Smoking rates continue historic drop, but cervical cancer prevention is lagging

The latest ACS cancer prevention and early detection report reveals mixed progress in major cancer risk factors, preventive behaviors, and screenings among US adults. Smoking rates have continued to decrease, while breast and colorectal cancer screening have rebounded, but cervical cancer prevention remains a concern.

SourceAmerican Cancer Society·JournalCancer Epidemiology Biomarkers & Prevention·DateApr 23, 2025

Empathy might be retained in Alzheimer’s disease

A new study led by University College London researchers found that people with Alzheimer's disease scored slightly higher on a measure of empathy than peers with mild cognitive impairment. Despite this, emotional reactivity to negative emotions was heightened among those with Alzheimer's disease, contributing to difficulties regulatin...

SourceUniversity College London·JournalAlzheimer s & Dementia·TypeSystematic review·DateApr 23, 2025

How does climate policy uncertainty affect energy stock returns?

A recent study by International Studies of Economics found that climate policy uncertainty causes stocks to plummet globally, as investors fear damage to economic activity and carbon costs. The study also revealed that rising oil prices have a negative impact on stock returns, except in the Gulf Cooperation Council region and Kuwait.

SourceWiley·JournalInternational Studies of Economics·DateApr 23, 2025

Current AI risks more alarming than apocalyptic future scenarios

A study by the University of Zurich found that respondents prioritize present AI risks over hypothetical future threats, highlighting the importance of addressing actual problems. The research suggests a need for concurrent understanding and appreciation of both immediate and potential challenges in public discourse.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·TypeSurvey·DateApr 23, 2025

Therapist in your pocket

A team of researchers from Kyoto University has developed a smartphone app that teaches core techniques of cognitive-behavioral therapy (CBT) to treat subthreshold depression and anxiety. The app, RESiLIENT, was tested in the largest-ever individually randomized trial of its kind, showing promising results with no serious adverse effects.

SourceKyoto University·JournalNature Medicine·TypeRandomized controlled/clinical trial·DateApr 23, 2025