Researchers found 148 fungi-associated genetic variants linked to 9 fungal taxa and associated with chronic disease risk. The study sheds light on the human genetic determinants of the mycobiome, a previously understudied group of gut microorganisms.
Altmetric introduces AI-powered sentiment analysis to provide deeper insights into research public response and impact. The new feature leverages advanced technology to interpret and visualize sentiment behind mentions on key social media platforms.
Only 4 in 10 US retail pharmacies carry buprenorphine, a highly effective opioid addiction treatment, with disparities persisting in minority neighborhoods. Tight pharmacy regulations discourage pharmacies from carrying the treatment, limiting access to vulnerable communities.
Researchers developed CerviPro, a multimodal deep learning model that accurately identifies high-risk patients with locally advanced disease. The model achieved superior predictive performance compared to conventional methods and provided critical prognostic insights.
A clinical trial led by Professor Robert Bals found that azelastine nasal spray significantly reduced the risk of SARS-CoV-2 infection by 66%. The treatment group showed fewer symptomatic infections and lower respiratory rates compared to the placebo group.
The world's oceans absorbed significantly less CO2 in 2023 than expected, with the global marine carbon sink decreasing only moderately. Three physical and biological processes - CO2 escape, stratification of the water column, and the biological pump - counteracted CO2 outgassing and supported the sink's strength.
Researchers analyzed data from over 90,000 patients with heart failure and obesity to show that GLP-1 medications can significantly reduce the risk of hospitalization due to heart failure and all-cause mortality. The study found a greater than 40% reduction in these outcomes compared to a placebo group.
The Center for BrainHealth has welcomed 20 new advisory board members for 2025-2026, bolstering its depth of talent and expertise. The new board members will champion the center's mission to advance cognitive neuroscience research and promote brain health across the lifespan.
A new catalogue has been developed to geolocate over 200 cities in Spain and Latin America with names inspired by ancient Greece and Rome. The initiative, part of the ANTIMO project, provides a unique perspective on modernization and political models through classical references.
A new catalyst breaks down polyolefin plastics into liquid oils and waxes, which can be upcycled into higher-value products. This process bypasses the labor-intensive step of pre-sorting mixed plastic waste, making recycling more efficient and practical.
Scientists Sharon Swanger and Shannon Farris study how mitochondria in vulnerable memory circuits become overloaded with calcium, contributing to early memory breakdowns. Their research aims to find early signs of stress or failure in the entorhinal cortex-hippocampus circuit.
Researchers studying Tajikistan's Kyzylsu Glacier found that the glacier likely reached its tipping point in 2018, with decreasing snowfall causing it to melt. The study uses computational models driven by new local observations and demonstrates the importance of densifying observational data in understanding anomalous glacier behavior.
Scientists have discovered a distinct neurochemical signature that sets Parkinson's disease apart from essential tremor, two common movement disorders. In a new study published in Nature Communications, researchers identified unique chemical signaling patterns of dopamine and serotonin that distinguish these conditions.
A clinical trial has identified breast cancer survivors at high risk of recurrence due to dormant cells and successfully treated them with existing drugs. The study shows a 90% survival rate without disease recurrence in patients who received one drug and 100% for those who received both, offering new hope for breast cancer prevention.
The Exoplanet Travel Bureau's poster campaign successfully promoted exoplanets as vacation destinations by leveraging retro-style posters, virtual tours, and coloring books. The synergy between artists and scientists in this campaign revealed that scientists also make imaginative leaps to turn abstract data into concrete planet concepts.
Professor Siegfried Kasper reveals biological bases of psychiatric disorders alongside psychosocial determinants, influencing treatment protocols globally. His pioneering research transformed approaches to treatment-resistant depression, improving millions of lives.
Professor Gregor Hasler's pioneering research reveals how psychedelics like LSD, psilocybin, and MDMA enhance neuroplasticity, allowing the brain to rewire itself and break free from depression, PTSD, and addiction. His discoveries have the potential to fundamentally alter international approaches to mental health treatment.
Researchers at Max Planck Institute develop protocols for optimal mixing in cellular and microfluidic systems, overcoming energetic and fluid motion limitations. Their findings reveal a fundamental limit on information erasure efficiency, providing a theoretical framework for efficient engineering designs.
Researchers have developed a comprehensive assessment of socioeconomic vulnerability to climate change, integrating seven dimensions of vulnerability. The Global Data Lab Vulnerability Index provides crucial insight into which communities may be least prepared for climate impacts.
A new study by HKU ecologists reveals that intensifying El Niño events are disrupting arthropod populations across the tropics, leading to ecosystem function loss and destabilization. The team found significant biodiversity loss in multiple types of arthropods, with declines linked to weaker decomposition and herbivory processes.
Researchers developed a technique to study embryonic implantation in mice by keeping mouse uterine tissue alive outside the body. The method showed over 90% efficacy for implantation and provided insights into the maternal-embryonic signaling process.
Researchers at Aarhus University discovered that the crystalline material AgGaGe₃Se₈ exhibits a thermal conductivity of just 0.2 watts per meter-kelvin, three times lower than water and five times lower than typical silica glass.
Researchers found that narcolepsy patients exhibit similar slow brain pulsations to healthy individuals during sleep, but with distinct differences in intensity. The study suggests that orexin may suppress brain pulsations, linked to impaired brain clearance, a potential target for treatment.
In graphene, electrons behave like a perfect fluid with electrical properties described by a universal quantum number. Researchers discovered this property in exceptionally clean samples of graphene, observing an inverse relationship between electrical and thermal conductivity.
Scientists at Saarland University have developed a pioneering robot-assisted procedure for joint replacement surgery, eliminating the need for bone pins and external infrared cameras. The new approach uses the robot's built-in sensors to precisely scan the surgical field and create an accurate 3D model.
The percentage of births via cesarean section increased from 20.27% before the COVID-19 pandemic to 21.19% during the pandemic, peaking at 22.14% during the sixth wave.
Researchers analyzed 139 neuroimaging studies on cognitive conflict tasks across 3,765 participants aged 5-85, revealing an inverted U-shaped lifespan developmental trajectory in brain activities associated with cognitive control. The peak age of brain activity was found to be between 27 and 36 years.
A new study found that over 34% of children don't engage in outdoor play on school days, while one in five don't at weekends. This lack of outdoor play is linked to various health issues, including obesity, anxiety, and depression. The research highlights the importance of creating safe and welcoming spaces for children to play outside.
A team of researchers from TU Wien and NUS has successfully observed the production of syngas using operando TEM combined with computational simulations. The results show that a synergy between palladium and palladium oxide is necessary for efficient catalysis, with the two phases taking on different tasks.
Researchers have identified a new class of compounds derived from psychedelics that could open the door to safe, targeted therapies for widespread use in clinical settings. These PIPI drugs may modulate the immune system to control inflammation, potentially treating conditions such as Alzheimer's and Parkinson's disease.
A new study uses machine learning to optimize the adsorption capabilities of biochar for dye removal, identifying optimal conditions for maximum efficiency. This research has significant implications for addressing water pollution and achieving environmental sustainability.
A global review highlights the need for better tools to understand juvenile fish habitats, which are facing increased pressure from various factors. The study recommends incorporating metrics like growth, survival, and contribution rates to assess habitat quality.
A growing body of research highlights the emotional complexities of providing animal care, with veterinarians facing high rates of burnout and mental health issues. Dr. Marie Holowaychuk's new book aims to foster greater empathy between pet owners and veterinary professionals.
The study reveals that when physical constraints are removed, human mobility follows a power-law pattern, decreasing steadily with distance. The researchers found this pattern across five orders of magnitude, from 10 meters to hundreds of kilometers.
Researchers have introduced a specialized AI model, EnvGPT, which achieves state-of-the-art performance in addressing complex environmental challenges. The model fine-tuned on a curated dataset outperforms larger models in accuracy and relevance, offering a scalable solution for environmental research and policy support.
A new policy review emphasizes the importance of standardized responder criteria for health-related quality of life data in clinical trials for people with advanced cancer. The approach evaluates whether new treatments improve patients' day-to-day lives, alongside traditional clinical endpoints like overall survival.
A large-scale database study has provided solid evidence for using semaglutide and tirzepatide to treat heart failure with preserved ejection fraction. The medications have been shown to reduce the risk of hospitalization for heart failure or death by more than 40 percent in patients with this form of the disease.
A research team from HKUMed developed a world-first nasal organoid-based SARS-CoV-2 Neutralising Antibody Evaluation Platform, enabling accurate assessment of antibody and vaccine effectiveness. The platform uses respiratory organoids that closely simulate human respiratory tissues.
Researchers have successfully developed human placental stem cells from full-term pregnancies, sharing characteristics with early pregnancy cells. These Ch-TS cells can develop into key cell types essential for proper placental function, offering a more relevant model to study late-stage complications.
A study of 2,201 patients after heart bypass surgery showed that dual antiplatelet therapy with ticagrelor and aspirin did not reduce cardiovascular risks but increased the risk of excessive bleeding. The results contradict current guidelines recommending dual therapy for these patients.
Researchers analyzed interplay between environment and income inequality, identifying theoretical mechanisms and empirical evidence. The study suggests that good climate policy can promote social balance by increasing labour productivity and wages.
A study by University of Otago researchers found that young adults who prioritize good sleep, eat more fruit and vegetables, and stay physically active experience improved well-being. These basic lifestyle behaviours can meaningfully enhance well-being without costly interventions.
Researchers found that immature neutrophils migrate into inflamed tissues upon stimulation by interferon-γ, suppressing inflammation and reducing tissue damage. In humans, these cells also produce interleukin-10, which increases in the blood of COVID-19 patients.
A new study from La Trobe University found that knee crepitus, a common symptom of grinding or clicking sounds in the knee joint, does not predict joint damage over time. In fact, those with knee crepitus showed more severe symptoms early on but did not experience worsening pain and function in the long term.
Researchers from The University of Osaka discovered that macrophages can directly engulf and digest damaged mitochondria through a process called microautophagy. This process allows lysosome-like compartments in macrophages to take in broken cell components directly, bypassing the need for digestion.
Researchers found that chronic stress triggers the release of immune cells in the brain's protective layer, contributing to depression symptoms. Blocking these cells' signaling pathway shows promise for improving behavior and alleviating depressive symptoms.
A team of researchers developed a scalable biological signal-processing framework that uses synthetic operational amplifiers to convert mixed cellular inputs into clean, orthogonal outputs. This enables precise, predictable control of complex biological systems, with applications in biomanufacturing and signal decomposition.
A recent study found that menin promotes bladder cancer malignancy by enhancing TFAP2C/β-catenin signaling, suggesting its potential as a therapeutic target and prognostic marker. Menin upregulates TFAP2C expression, which regulates β-catenin gene transcription via binding to its proximal promoter.
Researchers are collecting faeces from exotic animals at Dudley Zoo and West Midlands Safari Park to search for phages that can fight bacterial infections. The goal is to create a bio-bank of these phages to develop alternative treatments for life-threatening infections.
A team of researchers from China cloned the heat-stable RKN-resistant gene Mi-9 from Solanum arcunum accession LA2157, showing it confers heat-stable resistance to root-knot nematodes. The study demonstrates a roadmap for rapid characterization of resistance genes through comparative genomics and genome editing.
Researchers at Kaunas University of Technology (KTU) have developed new generation polymers made from renewable raw materials, with unique properties such as self-healing, shape memory, and antimicrobial effects. These sustainable solutions can be applied in various fields including medicine, electronics, and optics.
The journal, led by Professor SUN Jiaguang, has enhanced its academic impact through dedicated development, attracting international submissions from over 130 countries. Tsinghua Science and Technology will uphold its commitment to highlighting cutting-edge research and emerging trends in information science.
This lecture examines how Philippine Sinophone poet Grace Hsieh-Hsing developed a unique poetics that transforms the archipelago into a metaphor for artistic creation and cultural identity. Her work celebrates multiplicity, fluidity, and cross-cultural pollination.
A new study finds that tropical cyclone clusters are becoming less frequent in the Northwestern Pacific and more common in the North Atlantic. The shift is attributed to climate change, highlighting the need for strengthened coastal infrastructure and emergency response systems.
Scientists create nanoscale magnetic thin films with embedded functionality by controlling atomic spacing on flexible substrates. This breakthrough opens doors to novel materials and applications in electronics, healthcare, and energy efficiency.
A new study by Bournemouth University confirms that red squirrel populations across Europe are resilient to the effects of climate change, but highlights the need for conservation efforts to protect their habitat. The study found that temperature changes and low rainfall do not directly affect the survivability of red squirrels.
A new study has developed advanced, non-destructive models to measure the aboveground biomass and volume of Populus euphratica, a keystone tree in desert riparian forests. These models reduce errors by nearly half compared to traditional equations, providing new tools for forest conservation and carbon storage assessment.
Researchers capture unprecedented 130-year evolution of Planetary Nebula IC418, revealing significant changes in emission lines and implications for stellar evolution. The study offers unique evidence of how PN central stars evolve, prompting a rethink of existing models of stellar life cycles.
A new series published in The BMJ highlights the role of the arms industry in perpetuating conflict, injuries, and death, and argues that it should be seen as a commercial determinant of health. Health professionals are urged to advocate for a reorientation away from profit-driven design and deployment towards global priorities of heal...
A groundbreaking biography of Æthelstan highlights his overlooked achievements and the significance of his reign in shaping modern England. Woodman argues that Æthelstan created England in 927AD, citing evidence from original diplomas, literary records, and archaeological sites.