Researchers describe a novel disorder caused by biallelic loss-of-function variants in the TMEM63B gene, resulting in severe lung disease. The disorder presents with early onset respiratory distress, lung abnormalities, and developmental delay but no epilepsy.
Yalonda Howze joins C-Path's Board of Directors with nearly two decades of experience in biotechnology and life-science sectors. Her appointment aims to accelerate drug development and advance therapies for rare diseases.
A new study reveals that alpine species are more vulnerable to climate change due to their reliance on specific temperature cues for germination. Seeds from high-altitude plants showed strong dormancy patterns linked to elevation, while lowland species were more flexible and adaptable.
The Kavli Prize in Nanoscience 2026 is awarded to Eva Y. Andrei, Pablo Jarillo-Herrero and Allan H. MacDonald for their foundational work in Twistronics. This new paradigm in nanoscience enables the exploration of interaction-driven quantum materials.
Researchers found that people using illicit fentanyl regularly consume quantities equivalent to hundreds of times higher than hospital doses, contributing to high opioid tolerance and overdose deaths. The study aims to provide a more accurate understanding of fentanyl exposure and inform treatment protocols.
Researchers from the University of Michigan and Electra, a hybrid-electric aviation company, unveiled an advanced airliner concept that boasts a 17% efficiency improvement over standard aircraft. The design features a wide body and electric fans at the rear to reduce drag and provide thrust.
MIT researchers have developed low-cost, 3D-printed triaxial electrospray emitters that efficiently produce three-layered particles at scale. The devices can be used to manufacture time-release drug-delivery nanoparticles with potential applications in biosensors and tissue regeneration.
New research finds that conserving forest cover across coffee growing landscapes is essential for sustaining diverse bird communities, even more than farm-level shade tree management. Forest cover within a 2-kilometer radius positively predicted bird habitat-use across all ecological guilds, including species of conservation concern.
Researchers developed a silver nanoparticle-based technology to precisely cut and join DNA at targeted sites, increasing assembly efficiency by 2-5 times. The process uses chemical reactions instead of restriction enzymes, resulting in higher DNA recovery rates and improved joining efficiencies.
A study by King's College London found that following a short-term low-calorie diet can reduce markers of inflammation associated with gum disease. This suggests lifestyle modifications may be important alongside plaque control in managing gum disease.
Researchers identified a driver of inflammatory bowel disease, a group of biologically distinct diseases driven by different underlying mechanisms. Autoimmune responses to interleukin-10 lead to uncontrolled inflammation in ~3.5% of IBD patients, carrying a genetic variant linked to severe disease.
Dr. Corby Martin has been awarded the LPFA Endowed Chair in Nutrition at Pennington Biomedical Research Center for his groundbreaking research on nutrition and health behaviors. The chair recognizes his extensive experience leading interventions to modify health behaviors and outcomes, including food intake, exercise, and body weight.
Researchers at UC Irvine have discovered a mechanism that combines DNA damage and inflammatory signaling in tumor cells, potentially improving cancer treatment response. The study found that a combination of PARP inhibitors and TOP1 blockers triggers an 'alarm signal' inside cancer cells, alerting the immune system to eliminate them.
A new Canada Research Chair is being used to accelerate the energy transition and reduce dependence on fossil fuels for remote communities. Professor Jasmin Raymond's research program focuses on geothermal energy, green hydrogen storage, and natural hydrogen exploration to meet energy needs while minimizing environmental impacts.
A recent study by Semmelweis University found that alkaline mineral and medicinal waters can weaken the enteric coating of medications, reducing their effectiveness. The study analyzed 22 beverages and found that tap water was less damaging to the coating than acidic or alkaline liquids.
Researchers find that limiting methionine in the diet destabilizes DNA organization and leads to cancer cell death and increased animal survival. The study proposes a new connection between diet, gene regulation, and cancer growth, opening possibilities for treating aggressive brain tumors.
The Kavli Prize in Astrophysics 2026 is awarded to Vasily Belokurov, Amina Helmi, and Rodrigo Ibata for their discovery of past mergers that prove the Milky Way galaxy was built through hierarchical accretion. This breakthrough reveals how our universe is formed and challenges assumptions on galaxy formation.
The University of Maryland School of Medicine is establishing a new Center for Combat Casualty Care with a $1 million state grant. The center will include a sensitive compartmented information facility and train military clinicians in the development of new medical tools and treatments.
A new study by Tulane University researcher Sönke Dangendorf found that human-caused sea-level rise has significantly increased the frequency of extreme coastal flooding worldwide. Coastal flooding events expected once every 100 years now occur on average about 12 times more likely to occur globally.
A new telescope technology, featuring a metasurface component, can collect scientifically meaningful data from the Sun in a single snapshot. This technology solves problems in space missions by stabilizing telescopes and reducing costs.
A new study found that HPV-DeepSeek, an ultrasensitive blood test, can identify patients with HPV-associated head and neck cancer who may benefit from additional treatments. The test detected circulating tumor DNA in 98.1% of patients at diagnosis, significantly improving detection rates compared to existing methods.
The study aims to analyze the evidence on resistance training and aerobic exercise in improving quality of life and heart health for older adults. Conducted by members of The People's Review, it will provide valuable insights into the effectiveness of these exercises in addressing age-related health concerns.
A study by Baylor College of Medicine researchers identifies a set of dysfunctional genes and specific cell types that are vulnerable early on to genetic changes in Rett syndrome. The research reveals that even healthy cells can be influenced by their environment, contributing to widespread brain dysfunction in the disease.
A study published in PLOS Global Public Health reveals a significant regulatory inconsistency in the management of products associated with fatal self-harm, including firearms, pesticides, and alcohol. The authors argue that a more consistent approach is needed to prevent suicide by treating known harmful products as the problem, rathe...
Research reveals that dead foundation species continue to influence ecosystems through their physical remains, promoting recovery in some cases and hindering it in others. This understanding can help manage and restore ecosystems, reducing the need for expensive interventions.
Research suggests fish and shellfish harvests played a key role in the economic system of the Canary Islands. Archaeologists found specialized fishing tools, thousands of fish scales, and evidence of early food preservation techniques.
A study of 2,044 older Japanese adults found that lower vitamin C levels were associated with lower gray matter volume and reduced connectivity within the default mode network. Optimal vitamin C levels may support cognitive function, but further research is needed to explore the biological mechanisms.
The University of Bath has recruited leading psychiatric geneticist Professor Laura Huckins to lead mental health research, focusing on eating disorders and PTSD. She aims to provide answers and treatments for vulnerable populations, combining genetic data and human brain studies to predict individual responses to their environment.
Monash University researchers found that exercise may boost muscle mass and strength in older adults by boosting a key protein called NOX4, which naturally declines with age. The study suggests restoring NOX4 levels could combat biological ageing and improve overall health.
New degradable sensors developed by Lancaster University researchers track biological activity in soil using a biodegradable substrate nibbled on by microbes. This technology offers insights into soil's response to climate events and storage of carbon, providing a better understanding of soil health and microbial processes.
Research by Lancaster University and the Indian Institute of Technology, Kanpur found that vulnerable families coped with food insecurity by limiting food diversity, taking loans, and temporarily withdrawing children from school. The study highlights the importance of local social networks and government support in mitigating crisis.
The Konstanz 'Village Lab' project will create an interdisciplinary programme on democracy in rural areas, providing students with hands-on experience. The four-year project aims to prepare students for active roles in shaping democratic processes and strengthening societal dialogue between the university and local regions.
Research published in Frontiers in Endocrinology reveals gestational diabetes influences fetal metabolic programming, shaping future risk of obesity and diabetes. Biomarkers such as leptin and adiponectin may identify children at increased risk, enabling personalized preventive strategies.
Psittacosis is experiencing a notable resurgence in China, driven by increased diagnostic awareness and metagenomic next-generation sequencing. The disease has significant gaps in current knowledge, including inadequate characterization of molecular epidemiology and lack of unified national surveillance framework.
A new study led by Penn State researchers found that just four minutes of daily strengthening exercise can significantly improve key factors in quality of life for aging adults. The study showed that strength and mobility improved dramatically in adults aged 65 and older, leading to better independence and reduced fall risk.
A new Brookings Institution study found that ICE surges have caused significant job losses in cities where enforcement is most active. Between 51,000 and 297,000 American-born workers lost their jobs due to the surges, which also led to widespread disruptions throughout industries such as construction.
Four SfN members, Christine Holt, Kelsey C. Martin, Erin Schuman, and Oswald Steward, have been awarded the 2026 Kavli Prize in Neuroscience for their discoveries on local protein translation in neurons.
Researchers found that ground subsidence has undergone phases of variable change, creating significant implications for coastal communities. The rate of vertical land motion is nonlinear in many coastal areas, particularly in Louisiana and the Mississippi Delta.
A team of University of Amsterdam researchers show that activity can fundamentally alter the transition from disorder to order in soft matter physics. For living cells, bacterial chains and clusters of worms, this process is more complex, with activity preventing the formation of a fully ordered state.
A clinical trial found that abatacept significantly reduces the progression to rheumatoid arthritis in patients with palindromic rheumatism. Patients treated with abatacept experienced improved symptoms and reduced risk of developing arthritis, compared to those receiving hydroxychloroquine treatment.
Researchers have discovered a 'galaxy-killing wind' that could explain the origin of massive dead galaxies in the early universe. Using JWST and ALMA, they imaged a galaxy one billion years after the Big Bang, revealing a huge plume of cold gas extending far away from it.
A new study from the University of Copenhagen found that combining fractions with a basketball improves pupils' mathematical skills in primary school. Pupils who participated in an eight-week teaching programme performed 15% better in fractions tests compared to a control group.
Childhood maltreatment alters fear-related brain function and systemic inflammation, modulating their connection. The timing and type of abuse or neglect shape this link, with early trauma affecting threat-regional brain areas and late trauma impacting regulatory brain regions.
A comprehensive study reveals the Bornean ferret badger is found only in Sabah's western highlands, with a previously unknown population discovered in Nuluhon-Trusmadi Forest Reserve. The species' range and distribution are largely confined to mountain landscapes, highlighting the need for conservation efforts to protect its habitat.
A new study found that individuals with a 'Sleep Appreciate' profile are willing to pay more for better sleep, while those with a 'Sleep Devalue' profile require less money. The research suggests integrating economic perspectives into sleep health research may offer novel insights for designing interventions.
A study by DZNE shows that smartphone-based memory tests can detect subtle cognitive decline in people with mild cognitive impairment (MCI) more quickly than conventional testing. This approach has the potential to accelerate clinical trials for new dementia drugs and be used in routine care.
Researchers are investigating the role of MYRF in HLHS, a severe congenital heart defect requiring multiple surgeries. The study aims to better understand how MYRF regulates heart development, with potential implications for improved care and long-term outcomes.
Dr. Donald Lloyd-Jones, a renowned cardiologist and director of the Framingham Heart Study, has been honored with the American Heart Association's Gold Heart Award for his groundbreaking work in promoting cardiovascular health and preventing cardiovascular diseases. His research focuses on the mechanisms and life course of cardiovascul...
The study demonstrates a direct hydrazine substitution strategy to construct fused heterocyclic energetic skeletons with tunable structural and energetic properties. The compounds exhibit exceptional thermal stability and low impact sensitivities, making them suitable for heat-resistant applications.
Researchers detected pathogenic species of Sporothrix in the internal organs of mammals, birds, and reptiles that were killed by vehicles on Brazilian roads. The study reveals a new reservoir for fungi, highlighting the need for surveillance.
The review highlights advances in multi-scale bioelectrical interactions, analyzing challenges such as interface impedance and material-tissue compatibility. It emphasizes a shift towards application-driven design, integrating biological needs with material selection and device engineering.
A new study from Penn State College of Medicine found that excessive daytime sleepiness is associated with a higher risk of both prevalent and incident hypertension. Individuals reporting excessive daytime sleepiness had 52% higher odds of prevalent hypertension and 74% higher odds of incident hypertension compared to normal controls.
As precision agriculture technologies spread, on-farm experimentation has become increasingly common, generating vast amounts of data that require advanced analytical approaches. Researchers are now using statistical methods like linear mixed models and Bayesian approaches to handle the complexity of real-world data, enabling farmers t...
Old Dominion University has launched a National Security Institute to accelerate research and technology solutions for pressing national security challenges. The institute will bring together researchers' strengths in AI, autonomy, and coastal systems to deliver innovative solutions.
A new drug targeting RAS, a pathologically altered protein causing 40% of colorectal and 90% of pancreatic cancers, has been developed. The molecular eraser, RIBOTAC, stops the production of RAS by degrading its mRNA, but surprisingly triggers changes in cancer cells despite minimal impact on protein quantity.
Researchers have found that wheat plants can produce natural compounds that suppress nitrifying microbes in the soil, reducing nitrogen losses. The study screened 18 benzoxazinoids and found seven capable of strongly suppressing nitrification, with benefits for fertilizer efficiency and climate change mitigation.
A recent study published by the University of the Basque Country found that girls are the biggest consumers of psychotropic drugs among adolescents in most European countries. The research team analyzed data from 32 European countries and discovered a significant link between consumption rates, gender equality, and economic level.
Researchers at Baycrest have made significant contributions to the understanding of paratonia, a common yet underrecognized condition in advanced dementia. The studies explore clinical features, recognition, and assessment approaches, emphasizing the need for more compassionate and person-centered care.
A new study found that surgical menopause causes more severe genitourinary syndrome of menopause phenotype, with increased symptoms and exam findings compared to natural menopause. This may lead to a higher risk of vaginal dryness, pain during intercourse, urination, reduced sexual desire, and postcoital bleeding.
James Dante, a leading expert in corrosion science, has been named Fellow of the Association for Materials Protection and Performance. He is renowned for developing laboratory test methods to predict corrosion and coating system degradation, and his work has been instrumental in standards development.