Construction on Sandia's largest project of the past decade is nearing completion with the installation of the final beam. The 136,000-square-foot facility will replace an aging site and provide a more efficient design for power sources research and development. Completion is expected in 2028 at a projected cost of $400 million.
A first-in-human trial shows that an infusion of immune cells derived from a donor's blood can prime the recipient's immune system to accept a donor liver, potentially reducing lifelong immunosuppression. Eight out of 13 participants achieved complete withdrawal of immunosuppression and remained off for more than three years.
Scientists at Kyushu University have developed a simple method to produce hydrogen gas by mixing methanol with iron ions and irradiating it with UV light. The reaction produces a considerable amount of hydrogen gas comparable to that of previously reported systems, opening up new possibilities for sustainable hydrogen technologies.
Researchers have successfully imaged the detailed workings of a cell membrane protein, called TMEM16 scramblase, which has essential roles in all animals. The discovery could lead to new therapeutic strategies for blood coagulation disorders, cancers, and other conditions in which the protein works abnormally.
A new report published in Nature Metabolism sheds light on fructose's distinct role in driving metabolic disease, separate from its caloric contribution. Fructose bypasses key regulatory steps, leading to increased fat synthesis and cellular energy depletion, which may contribute to metabolic syndrome.
A team of undergraduate students built a cavity detector to search for axions and set new experimental limits on their properties. The result was achieved with relatively limited resources, showcasing the potential for small-scale experiments in precision cosmology.
Researchers found that incorporating data from ocean bottom seismometers could improve ShakeAlert's detection time by 5-9 seconds. This technology has the potential to increase warning times for regional offshore earthquakes by up to 40 seconds.
The study demonstrates the potential for rapid deployment of fiber optic cable and Distributed Acoustic Sensing in environments where burying the cable isn't feasible, capturing aircraft speed and maneuvering.
A unique machine learning study identified over 60,000 earthquakes during the 2025 Santorini seismic crisis. The researchers found six times more earthquakes in the first 30 days compared to traditional monitoring, providing insights into fault networks and magma movement.
Emerging AI technologies are enabling faster, smarter, and more integrated solutions to global challenges. AI-powered systems can track pollution levels, detect anomalies, and predict future risks in water, soil, air, and waste systems.
The BioCAT beamline supports techniques including fiber diffraction, micro-diffraction, and small-angle X-ray scattering for studying biological systems. The facility has produced nearly 800 articles cited over 58,000 times, with an h-index of 114.
A newly-developed AI-powered tool, CAMPER, helps identify peptides that target antibiotic-resistant bacteria by breaking down their outer defenses. The study found that CAMPER is effective in developing treatments against MRSA and other difficult-to-treat pathogens.
Researchers discovered that the river flowed into an upstream lake before flowing into the Grand Canyon, marking its transition to a continental-scale river. The study provides new insights into the formation of the Grand Canyon and the Colorado River's path.
A 42-year-old theory about children's body mass index (BMI) decrease before continuous rise is refuted by new analysis. Increasing muscle mass, not fat, causes the increase in BMI seen around age 5-7 years.
Researchers at Ohio State University Wexner Medical Center are refining specialized lymphatic microsurgery techniques to treat and prevent lymphedema. The new procedures, including lymphatic bypass and lymph node transfer, offer patients more options and improved quality of life.
Researchers at UCF used human-on-a-chip technology to study how genetic mutations associated with familial Alzheimer's affect movement. They found that motor deficits may be an early indication of Alzheimer's disease, which could help delay central nervous system symptoms.
A new study from MIT chemists found that changing the composition of the cell membrane can alter the function of a membrane receptor promoting cell growth. Elevated levels of negatively charged lipids can lock the receptor into an overactive state, contributing to cancer cell proliferation.
A recent study by researchers at the Netherlands Institute for Neuroscience suggests that softer, flexible brain implants may be gentler on the brain than older designs. While they have not been proven completely harmless, these new materials could bring long-term, reliable implants closer to reality.
A new MIT study suggests that exposure to NDMA, a chemical contaminant in drinking water and some medications, can cause cancerous mutations more severely in children than adults. The researchers found higher rates of DNA damage and cancer in juvenile mice exposed to low levels of NDMA.
The Estonian Research Council partnered with Luunja Stud Ltd to create the first cloned foal, named Wodan M Alpha, using a genetic copy of successful competition horse Wodan M. This achievement marks an important step in preserving genetics of top-performing horses and conserving endangered breeds.
Researchers found that sleep deprivation alters the composition of gut microbiota, leading to worse cancer progression and reduced effectiveness of chemotherapy. The study highlights the importance of maintaining a healthy microbiome through good sleep and diet.
Professor Thierry Chevalley has received the prestigious IOF President's Award for his significant contributions to advancing bone health and osteoporosis prevention. With extensive research expertise in geriatrics and bone health, he serves on various scientific committees and leads efforts to develop fracture liaison services.
A study published in Geology found that up to 75.7% of landslides occur during low or no rainfall periods, with early-stage rainfall reaching the sliding surface through three runoff supply modes and two migration stages. The team recommends mass monitoring, public education, and engineering mitigation measures to prevent such disasters.
A new study led by Dartmouth Cancer Center identifies key barriers to timely head and neck cancer treatment in rural areas, including transportation and caregiver challenges. The research highlights the importance of dedicated staff, strong community ties, and peer support in navigating the complexity of cancer care.
A study of over 1.27 million federal complaints found that older Americans and veterans receive slower responses than the general population, with a widening gap over time. The trend is particularly concerning for elderly residents in economically disadvantaged zip codes, who face the widest gaps in response times.
A new study reveals that freshwater fish are accumulating antidepressants, opioids, and other drugs of abuse in their bodies, which can alter their behavior, development, and reproduction. The research uses a novel analytical method to detect these substances in small fish living in rivers receiving urban wastewater.
Researchers at WashU Medicine discovered that mRNA vaccines can trigger strong anti-tumor responses even without certain immune cell subtypes, suggesting a novel pathway for cancer treatment. The study found that both cDC1 and cDC2 dendritic cells play a role in stimulating T-cell responses.
A Reproductive Justice (RJ) lens is crucial for addressing systemic inequities in high-risk pregnancy care, argues a new commentary. This approach recognizes that structural forces, not just medical factors, shape the options available to families navigating complex fetal diagnoses.
A bidirectional brain-computer interface (BCI) allows individuals with spinal cord injuries to control a robotic exoskeleton using brain signals and receive artificial leg sensation. The system, developed by UC Irvine researchers, demonstrates high accuracy in step counting and sensory discrimination tasks.
Artificial intelligence models provide personalized advice, but may perpetuate negative stereotypes about people with autism. Researchers found that up to 70% of the time, AI discourages those with autism from socializing.
A rare scalp reaction resembling erosive pustular dermatosis was identified in a lung cancer patient treated with amivantamab following cranial radiotherapy. The reaction appeared to be related to impaired wound healing due to dual inhibition of EGFR and MET signaling pathways.
A recent study by University of Ottawa professor Abel Brodeur found that 85 percent of social-science papers are computationally reproducible, suggesting improved norms for data sharing and code disclosure. This encouraging result aims to advance science and improve public trust in research.
A new study found that methylsiloxanes, a widely used industrial chemical, are present in the atmosphere across diverse environments, with concentrations up to 4.3% of total organic aerosols. The discovery raises concerns about potential health risks and climate impacts, highlighting the need for further research on these unknown effects.
A new study by University College London found that gabapentinoids, prescribed for chronic pain, double the risk of hospitalization for drug poisoning when combined with benzodiazepines or opioids. The risk persists even after starting gabapentinoid treatment, suggesting they may not be an effective solution to reduce poisoning risks.
Large, warm-bodied fish like sharks and tuna require nearly four times more energy than other fish due to their ability to retain metabolic heat. This comes with elevated energetic costs, which may constrain body size and contribute to extinction risk in both living and extinct species.
A team of researchers has discovered over 3,700 new bacteria species in coral reefs, each producing unique bioactive compounds with vast industrial and medical applications. The findings reveal the immense genomic potential of reef-building corals and highlight the importance of conserving these ecosystems.
Researchers have discovered a novel gene therapy aimed at eventually regrowing limbs in humans, building on studies of axolotl, mice and zebrafish. The breakthrough could potentially replace prosthetics with fully functional limbs.
New research reveals that the US-Israel-Iran war is threatening the food security of millions worldwide by increasing fertilizer costs, fueling speculative spikes in commodity prices, and undermining physical and sociocultural food environments.
Researchers at IBEC and EMBL develop a strategy to program tissue shape changes by controlling cell orientation. The team creates living tissues with reproducible three-dimensional structures, enabling applications in tissue engineering and biohybrid robotics.
A study by Brazilian researchers found that moringa oleifera's saline extract can effectively remove microplastics from water, similar to aluminum sulfate. The treatment method uses in-line filtration and coagulation to destabilize particles and filter out pollutants.
A new study explores potential options for Venice to adapt to sea-level rise, including relocating the city, movable barriers, ring dikes, and closing the Venetian Lagoon. The research suggests that no single approach is optimal, requiring a balance of factors such as resident wellbeing, economic prosperity, and cultural heritage.
Researchers at University of Wisconsin-Madison develop a systematic study for sustainable production of malonic acid via oxidation of 3-hydroxypropionic acid with a Pd/Carbon catalyst. The kinetic model validated the network, displaying excellent agreement and providing insight into conditions that maximize MA production.
Professor Noriko Yoshimura has received the IOF CSA Medal of Achievement for her pioneering work on epidemiology and prevention of locomotive organ disorders and osteoporosis. Her research, including the ROAD Study, has significantly advanced understanding of musculoskeletal health.
Astronomers used TACC supercomputers to develop models of Little Red Dot formation, finding better agreement with Direct Collapse Black Hole theories. Researchers also analyzed JWST data using a 'genetic technique' to understand the history of these enigmatic cosmic objects.
Researchers have made a breakthrough in developing a novel platform that harnesses the immune system's ability to produce therapeutic proteins. By editing hematopoietic stem cells with CRISPR gene-editing tools, they were able to create a long-term, boostable source of antibodies capable of protecting against deadly influenza infection...
Dr. Peter Walter joins Buck Institute as Professor to explore fundamental mechanisms of cell health and translate insights into age-related disease prevention and treatment strategies. His work has had a lasting impact on biology, transforming understanding of cellular health and disease.
Researchers suggest that an ancient lake overflowed 5.6 million years ago, establishing the Colorado River's course through the Grand Canyon. The study used uranium-lead dating to confirm a shared sediment source and indicate that the ancestral river was connected by 6.6 million years ago.
Rapidly growing commercial prediction market platforms raise concerns over democratic manipulation, addictive design features, and potential health risks. The authors call for informed regulatory action to address these issues.
Researchers have developed a technique to detect and measure the concentration of rare-earth elements in plants without destroying them. The method uses fluorescence spectroscopy to distinguish between autofluorescence from plant matter and rare-earth element uptake.
The study provides a roadmap for understanding and treating liver cancer by identifying key biological processes that enable tumors to grow and spread. It highlights the potential for precision medicine approaches, including immunotherapy and targeted therapies, to improve outcomes for patients with liver cancer.
Researchers at ISTA report that Anabaena develops a cytoskeleton to control cell shape, transforming an ancient DNA segregation system. This evolutionary shift enables the bacteria to sculpt their cells without relying on traditional spindle-like structures.
A new study suggests that minimally invasive surgeries like robotic and laparoscopic approaches can be successful for gallbladder cancer in carefully selected patients. The review found that these procedures often resulted in less blood loss, shorter hospital stays, and more lymph node removals, with comparable long-term cancer outcome...
Research reveals warm-bodied fish like sharks and tunas burn nearly four times more energy than cold-blooded counterparts, exacerbating the impact of warming oceans. As a result, these species are facing an increasing risk of overheating and habitat loss.
NIST scientists have measured the gravitational constant, a decade-long pursuit that aimed to resolve the mystery of gravity's strength. The measurement was achieved through a precision experiment that replicated an earlier study, providing a more accurate understanding of big G, a fundamental force in nature.
A study reveals that the rhinovirus, causing the common cold, can infect immune cells in the tonsils and adenoids, remaining dormant for extended periods without symptoms. This persistence allows for unexpected transmission and triggers new outbreaks, particularly among children, who are a primary mode of transmission to grandparents.
Research finds over 3,000 genes with sex-biased transcription in the brain, including genetic variants linked to ADHD, schizophrenia, depression, and Alzheimer’s disease. Sex differences may arise from interplay of biological and social influences.
Research from Saarland University reveals gifted individuals tend to be less conservative than their average-intelligence peers. However, social conservatism among men differs significantly between the two groups.
Researchers introduce EBDA, a novel framework that replaces traditional PKI certificate systems with a blockchain-maintained Graph of Trust (GoT), enabling fully decentralized identity authentication for vehicles. The approach reduces authentication latency by at least 22.93% while maintaining low computational and storage overhead.
Researchers at Peking University have developed a general nanofabrication strategy for van der Waals materials, allowing for the creation of low-loss and high-performance photonic structures. This enables the demonstration of efficient continuous-wave nonlinear optical processes in vdW microcavities.
Researchers find that brief exposure to prallethrin-based insecticides used in mosquito repellents significantly impairs bumblebees' ability to navigate back to their nests. This impairment can lead to reduced food collection and ultimately threaten the survival of entire colonies.