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Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign


Illinois and Syngenta sign agreement for access to RIPE intellectual property

The University of Illinois and Syngenta have signed an agreement to implement a commercialization strategy for the 'RIPE' project, which aims to improve photosynthetic efficiency in food crops. The partnership brings together academic groups with industry partner Syngenta to advance technologies developed under the project.

Straight up, with a twist: New model derives homochirality from basic life requirements

A new mathematical model developed by University of Illinois physicists suggests that homochirality can be used as a universal biosignature. The model, based on self-replication and disequilibrium, shows that homochirality appears when self-replication is efficient enough.

Past and present genomes tell the story of Native American biological origins

A study of ancient and modern genomes clarifies the history of Native American migration to the Americas, tracing their ancestry back to a single late Pleistocene event. Genetic analysis reveals two distinct populations: Athabascans and northern Amerindians, diverging from shared ancestors at around 23,000 years ago.

Evolutionary trees reveal patterns of microbial diversification

Researchers have created a new microbial 'family tree' that displays sudden bursts of diversification, potentially helping understand how harmful microbes evolve. This breakthrough uses coarse-graining and Λ-coalescent models to condense short branches into larger nodes, revealing patterns of ecological processes.

SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalProceedings of the National Academy of Sciences·DateJul 15, 2015

University of Illinois awarded $3.1 million to develop all-terrain rovers for high-throughput field phenotyping

The University of Illinois will lead a $3.1 million project to develop all-terrain automated ground rovers for high-throughput field phenotyping. These rovers will measure crop growth using 3-D reconstruction and various sensors, enabling faster breeding of energy sorghum and other bioenergy crops.

Travertine reveals ancient Roman aqueduct supply

A study of travertine deposits in the Anio Novus aqueduct revealed an actual estimate of its flow rate, significantly lower than previous estimates. The aqueduct's average water level indicates it was almost always full of water, supplying Rome with a reliable water supply that enabled urbanization during the first century AD.

Many experiments for the price of one -- a breakthrough in the study of gene regulation

Researchers developed a novel approach to deciphering gene regulation networks by leveraging biological knowledge and computational algorithms. They found that combining laboratory experiments with motif information can accurately predict DNA-binding behavior of transcription factors.

Monkey droppings complement field observations, researchers report

Researchers used high-throughput sequencing to analyze fecal DNA of saddleback tamarins, identifying 20 families and genera of invertebrates consumed. This study complements behavioral observations and ecological sampling, providing insight into the monkeys' foraging strategies.

Koala study reveals clues about origins of the human genome

Scientists discovered 39 different koala retroviruses passed down from parent to offspring, offering insights into the human viral lineage and koala conservation. The study found that these retroviruses integrated into the host genome less than 50,000 years ago and are linked to health issues in koalas.

A novel roadmap through bacterial genomes leads the way to new drug discovery

Researchers at the University of Illinois have developed a database that analyzes microbial genomic data to speed up the discovery of new therapeutic drugs. The database allows scientists to identify promising gene clusters and predict the production of natural products, enabling them to target specific bacterial strains for study.

Innovative technique may transform the hunt for new antibiotics and cancer therapies

Researchers develop new technique to quickly uncover novel products produced by bacteria, reducing screening time from thousands to just a few dozen. The method uses genomics and mass spectrometry to detect reactive compounds, enabling the discovery of new antibiotics and anticancer drugs.

Genomics for judges: Educating Illinois judges on how genetic info impacts court decisions

The Genomics for Judges seminar, offered by the University of Illinois, aims to educate judges on how genetic information affects court decisions. The two-day course covers DNA sequencing, gene function, and genome analysis, preparing judges to deal with legal questions involving genomics in the courts today and in the future.

New method of DNA editing allows synthetic biologists to unlock secrets of a bacterial genome

Researchers have developed a novel DNA engineering technique to discover potentially valuable functions hidden within bacterial genomes. By reprogramming gene expression, they were able to increase the production of previously unknown compounds with useful biomedical applications.

Researchers unmask centuries-old elephant imposter

A 300-year-old Asian elephant specimen has been reclassified as an African elephant due to genetic and physical evidence. The discovery confirms that the specimen, named Hansken, was likely from West Central Africa and challenges traditional understanding of the species' classification.

Illinois researchers advance understanding of schistosome reproduction

Researchers at the University of Illinois have characterized stem cells in larval schistosomes, which may help control the parasite's life cycle and potentially lead to its eradication. The study discovered molecular signatures similar to those found in free-living flatworms, allowing schistosome larvae to rapidly reproduce.

Cracking how life arose on earth may help clarify where else it might exist

A novel theory, proposed by Michael Russell and colleagues, suggests that life arose from geochemical processes, including serpentinization, which produced essential components for life. This theory could provide insights into the origins of life and potentially shed light on its existence elsewhere in the universe.

SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalPhilosophical Transactions of the Royal Society of London (B )·DateJul 30, 2013

Illinois chemical/bioengineers use adhesion to combine advantages of silicones and organic materials

University of Illinois bioengineers find way to permanently modify silicone polymer surface with organic material, resulting in stable adhesion for several months. The method enables practical applications in cell culture platforms, microfluidic devices, and tissue engineering.

Roy J. Carver Charitable Trust funds new research focus at Institute for Genomic Biology

The Institute for Genomic Biology will develop foundational synthetic biology technologies and computational platforms for genetic modification of plants and animals. The grant aims to address grand challenges in human health and environmental sustainability, with potential applications in crop yields and disease treatment.

University of Illinois to improve crop yield through photosynthesis in a new global effort

The University of Illinois has received a five-year, $25-million grant to boost the efficiency of key food crops like rice and cassava through improved photosynthesis. This project aims to increase crop productivity while reducing water and nitrogen usage, addressing the challenge of global food security.

Evaluation of microscopy techniques may help scientists to better understand ancient plants

Scientists at the University of Illinois have developed new microscopy techniques to analyze pollen grains, enabling better classification of prehistoric flora. The research highlights the importance of pollen morphology in understanding the evolution and diversity of ancient vegetation.

New tool in the fight against tuberculosis

A new tool has been developed to tackle tuberculosis by integrating genomic and metabolic data, enabling cell-scale simulations and biological strain design. The probabilistic regulation of metabolism (PROM) algorithm accurately predicts knockout phenotypes 95% of the time, paving the way for targeted research during dormancy.

SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalProceedings of the National Academy of Sciences·DateOct 7, 2010