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Ecole Polytechnique Fédérale de Lausanne


Robots offer clues to the impressive robustness of eel locomotion

A team of researchers has developed a mathematical model that integrates sensory feedback to enable eel-like robots to swim and crawl on land. The study shows how multisensory feedback enables eels to adapt their movement patterns after spinal cord injury, providing insights into the evolutionary transition of vertebrates from water to...

SourceEcole Polytechnique Fédérale de Lausanne·JournalProceedings of the National Academy of Sciences·DateSep 5, 2025

Breaking the code in network theory: Who leads and who follows?

A new algorithm, bimodularity, breaks the code in network theory by detecting not only which nodes belong together but also how information flows between them. This allows for the identification of bicommunities, where one community sends and another receives information, revealing new organizational structures.

SourceEcole Polytechnique Fédérale de Lausanne·JournalProceedings of the National Academy of Sciences·DateAug 26, 2025

Smart microscope captures aggregation of misfolded proteins

EPFL researchers have developed a 'self-driving' imaging system that can track and analyze protein aggregation in real-time and even anticipate its onset. The approach minimizes the use of fluorescent labels, allowing for accurate analysis. The new technology has important implications for drug discovery and precision medicine.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNature Communications·TypeImaging analysis·DateJul 24, 2025

Ultra-selective aptamers give viruses a taste of their own medicine

Researchers at EPFL have created ultra-selective aptamers that target specific binding sites on viral spike proteins with unprecedented precision. These multivalent binders show stronger and more selective binding affinities than traditional monovalent binders, making them promising for biomedical diagnostics and therapeutics.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNature Nanotechnology·TypeExperimental study·DateJun 6, 2025

Gut bacteria heal the colon

Researchers found that supplementing gut bacteria with Clostridium scindens can improve recovery from colonic injury and enhance regeneration of the gut lining. This approach targets the underlying issue: impaired ability of the gut to heal itself by restoring natural bile acid balance.

SourceEcole Polytechnique Fédérale de Lausanne·JournalEMBO Molecular Medicine·DateMar 10, 2025