Researchers found that inhibiting RUNX1, a gene linked to retinal neovascularization, presents a promising therapeutic advance for treating age-related macular degeneration. The study showed that a RUNX1 inhibitor alone or in combination with standard treatment reduced CNV lesion size and vascular leakage.
A new study in the Journal of Nutrition Education and Behavior has found that inconsistent information exists on commercial infant and toddler food packages, making it difficult for parents to understand what they are buying. This confusion can lead to early exposure to nutritious foods not helping children develop healthy eating habits.
The five winners are recognized for their accomplishments in chemistry, physics, and mathematics, as well as their commitment to leading and mentoring young scientists. The awards aim to support the careers of women researchers from developing countries and promote diversity in STEM fields.
A study published in JAACAP found associations between physical discipline, cognitive deprivation, and specific types of developmental delay. The research indicates that physical discipline is linked to a higher risk of socioemotional delay, while cognitive deprivation is associated with cognitive delay.
A new gene panel test developed by researchers allows for highly accurate diagnosis of liposarcoma types, distinguishing them from benign tumors and other cancers, with a success rate of 93% and costs of US$270 per case.
Research reveals that American adult cancer survivors often face barriers to healthy eating, with significant disparities observed across sociodemographic factors. A Mediterranean-style diet may reduce overall cancer risk for women, but not for men, highlighting the importance of personalized nutrition interventions in cancer care.
Researchers found that healthcare professionals have knowledge gaps when caring for LGBTQ2SPIA+ cancer patients, affecting their ability to provide emotional support and tailored care. The study concludes that patient-centered care requires specific resources and education for radiation therapists.
A new study reveals that specific enzymes outside medium spiny neurons contribute to addiction plasticity, driving drug-seeking and extinction behaviors. The discovery highlights the importance of extracellular matrix remodeling in addiction and suggests novel molecules as potential targets for treatment.
Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol called MultiMMR that can identify mismatch repair (MMR) deficiency in a single test. This alternative to complex testing workflows determines causes of MMR deficiency often missed by current clinical tests.
Aged African green monkeys developed severe respiratory distress syndrome (ARDS) with symptoms similar to those in human cases of COVID-19 after SARS-CoV-2 infection. The study suggests these monkeys may be suitable models for studying severe forms of COVID-19.
A study found that sudden deaths outside the hospital in New York City followed the geographic distribution of SARS-CoV-2, suggesting an association between the two. The rate of sudden death in 2019 was also predictive of increased sudden deaths during the pandemic surge.
Research from Purdue University and Oklahoma State University found that households purchasing food for children tend to buy more dairy products, including fluid milk and yogurt. This study provides insights into consumer behavior and can inform product marketing efforts and stakeholder decisions in the dairy industry.
Radiologists question the status quo to spark positive dialog and improve patient care. Featured articles debate the use of physician extenders and incorporation of AI algorithms into daily practice.
A survey of school nutrition staff in the US revealed significant concerns about COVID-19 transmission risks and lack of support from authorities. Respondents described feelings of exhaustion, fear, and stress due to high-risk working conditions.
New research highlights the challenges of providing childhood vaccinations in hard-to-reach populations and the emergence of vaccine hesitancy among wealthy families in low- and middle-income countries. Targeted interventions are needed to reduce inequality gaps and ensure universal coverage.
A longitudinal study of first-year university students found that those enrolled in the University of Vermont's Wellness Environment program had improved mood levels and fewer attention problems compared to non-participants. The study suggests that colleges and universities should track students' emotional health and develop specific p...
A new study published in The American Journal of Pathology reports that neutralizing tumor necrosis factor (TNF) can prevent rejection and tissue injury after cell transplantation, improving graft survival and regenerative medicine outcomes. TNF is identified as a master switch for orchestrating cytokines and inflammatory signals.
A new study in the Journal of Dairy Science found that heifers trained on a phantom before introducing an automated milking system visited the actual system more frequently, increasing milk yield. The training program reduced the need for human assistance during milking and prepared animals well for early lactation.
A new study published in the American Journal of Preventive Medicine highlights the devastating impact of structural racism on the health of foreign-born Blacks and Latinx. Chronic exposure to stressors erodes health, with significant disparities found among these groups compared to US-born individuals.
A study published in the Journal of Dairy Science found that kefir sweetened with demerara sugar or fructose has higher sensory acceptance scores and improves consumer emotions, leading to increased consumption.
A panel of experts developed guidelines for accurate determination of death in mountain rescue situations, taking into account the challenges of remote environments. Definitive signs of death include dependent lividity, rigor mortis, and decapitation, but absence of vital signs is not definitive.
Researchers found that self-collected saliva samples can reliably detect SARS-CoV-2 genetic material at a rate similar to nasopharyngeal and oropharyngeal swabs. The study also showed that saliva samples remained stable for up to 24 hours, providing a cheaper and less invasive option for COVID-19 testing.
Researchers found that individuals changed their behavior in reaction to COVID-19 presence 12 days before government lockdowns, underestimating the true impact of social distancing. Sociodemographic variables, such as education level and minority populations, were significantly associated with delays in social distancing behavior.
A recent study found that only seven percent of high-risk noncardiac surgery patients underwent preoperative screening for biomarkers, leading to increased mortality and complications. Researchers emphasize the need for improved compliance with guidelines and education among physicians.
A new study published in the Journal of the Academy of Nutrition and Dietetics found that exposure to small grocery stores with healthier inventories is associated with significant improvements in childhood obesity. In contrast, increased availability of convenience stores selling predominantly unhealthy foods was linked to a higher li...
A new longitudinal study found that individuals with autism spectrum disorder (ASD) experience significant cognitive gains between ages 12 and 23, with IQ increasing by an average of 7.48 points. Early language regression and greater communication problems at age 12 were associated with greater IQ increases.
A nationwide study investigates child nutrition administrative agencies' responses to meal service provision during school closures. Most jurisdictions provided easily interpretable information, but few offered comprehensive implementation guidance or communication with families.
The NCCU project aims to apply evidence-based findings into real-world applications, addressing health disparities in underserved communities. Community advisory boards and focus groups will be formed to engage communities and support mentoring and networking efforts.
A rapid review found extensive evidence of an association between loneliness and increased risk of mental health problems for children and young people. Loneliness is associated with both depression and anxiety, with some studies suggesting a three-fold increase in depression among lonely youth.
A new multiplex real-time RT-PCR assay has been developed as a simpler, more cost-effective alternative to existing SARS-CoV-2 testing methods. The assay performs comparably to the modified CDC test while allowing for increased patient throughput and reduced reagent consumption.
Researchers identified cytoplasmic localized histone deacetylase 6 (HDAC6) as a promising therapeutic target for OA. The study shows that Tubastatin A administration can postpone development of OA and improve cartilage degradation, suggesting it as a potential treatment.
A new study shows that getting only half a night's sleep hijacks the brain's activity during learning and memory consolidation, leading to increased vulnerability to conditions like anxiety and posttraumatic stress disorder. The research found that even partial sleep deprivation can be worse than no sleep at all.
Researchers found that mid-range levels of an immune marker at birth are associated with the lowest risk for autism spectrum disorder. Babies born with high levels of inflammation had a higher risk of developing ASD.
A brief five-week pilot intervention improved preschoolers' behavioral regulation and liking of fruits and vegetables. The study found significant gains in these skills among children who received the intervention, compared to those who did not.
A new study published in the American Journal of Preventive Medicine found that nearly 17% of patients who have recovered from COVID-19 can still test positive for the virus. Patients with persistent respiratory symptoms, such as sore throat and rhinitis, were more likely to test positive.
A rapid and affordable molecular assay using high-resolution melting technology accurately identifies antimicrobial resistant determinants in Neisseria gonorrhoeae, enabling real-time surveillance to control the spread of drug-resistant gonorrhea.
The study found that removing dairy cows from US agriculture would decrease nutrient supplies, particularly calcium and vitamins, while having a minimal effect on greenhouse gas emissions. However, this reduction in essential nutrients could pose challenges for feeding the human population.
The symposium highlighted the importance of resources and education to improve the quality and safety of milk in developing countries. Implementing technology training packages and workshops led to improved productivity, quality, and safety of milk production.
Researchers found that astrocytes play a critical role in forming synapses in response to cocaine exposure, which can contribute to addiction. Blocking these synapses may help prevent relapse, suggesting a new therapeutic target for substance use disorder.
A new study found that women in states with less restrictive reproductive rights policies are less likely to give birth to low-birth weight babies. Specifically, US-born Black women have a 7% lower risk of low-birth weight compared to those in more restrictive states.
A new study assesses nutrition-related features on leading US grocery store websites, finding that 85% of packaged foods have available nutrition facts panels and ingredient statements. However, key information is not always easily accessible or legible, particularly for mandatory labeling on product packaging.
The percentage of children and adults consuming high amounts of sugary beverages decreased significantly between 2003 and 2016. Notably, certain subgroups, including older adults and non-Mexican Hispanic adults, showed little to no improvement in their consumption habits.
Researchers found that abnormal amyloid deposits were present in fewer older adults with major depression compared to non-depressed control subjects. However, the study suggests that depression is still a risk factor for cognitive decline, but through a mechanism other than amyloid deposition.
A new study published in Mayo Clinic Proceedings finds that EPA and DHA supplementation reduces multiple types of cardiovascular risk, including coronary heart disease events and fatal heart attacks. The research concludes that increasing omega-3 intake through supplements or diet can contribute to cardioprotection.
A study of 607 women with severe migraines found 20% avoid pregnancy due to perceived risks, despite evidence that migraine improves in up to 75% during pregnancy. Women with menstrual-related attacks are more likely to delay family planning.
A study published in the American Journal of Preventive Medicine found that weaker gun laws in neighboring states are associated with increased gun deaths in adjoining states. The researchers analyzed 578,022 firearm deaths over a 17-year period and found that stronger state gun policies were linked to decreased firearm deaths.
Researchers found that levodopa stabilized and improved vision in patients with advanced age-related macular degeneration (AMD), reducing the number of treatments necessary. The drug's ability to target the GPR143 receptor led to a decrease in retinal fluid and an improvement in visual acuity.
A study identified three key factors that predict the first occurrence of nonsuicidal self-harm in adolescent girls: low conscientiousness, high avoidance, and parental substance abuse history. These psychological vulnerabilities were found to distinguish girls who initiated self-harm from those who did not.
A recent study by a team of researchers from the University of Bologna has shed light on the Minoan system of fractions, revealing that the lowest fraction is 1/60. The results have significant implications for understanding the Linear B script and its use in measuring units of measurement.
Researchers developed a machine learning approach to examine placentas, decreasing healthcare costs and allowing more women to be informed of their health risks. The algorithm can identify diseased blood vessels indicating preeclampsia risk with high accuracy.