Researchers found that destroying 25% of a one-hectare Atlantic rainforest fragment can raise the local temperature by 1°C. Clear-cutting the entire fragment would increase temperatures by up to 4°C, threatening the biome's carbon balance.
Researchers at the University of São Paulo, Adolfo Lutz Institute, and Oxford University have published the complete genome sequence of SARS-CoV-2 in Brazil. The study reveals differences between the genomes of viruses isolated from two Brazilian patients, suggesting internal transmission is occurring in European countries.
Researchers in Brazil identified a gene expression profile associated with cachexia, a potentially fatal syndrome characterized by severe weight loss and muscle wasting. The study found that pancreatic, esophageal, colorectal, stomach, and head-and-neck cancers are most frequently linked to cachexia.
A Brazilian research group uses VideometerLab, a multispectral imaging instrument, to analyze pupae and detect dead or empty insects. The device provides precise data on sample quality, improving the efficiency of biological control.
A study found that prenatal hypoxia may contribute to schizophrenia by altering the functioning of astrocytes and mitochondria. Researchers investigated the effects of hypoxia on rat astrocytes and observed changes in mitochondrial calcium balance, which can lead to cell death.
Brazilian researchers found a correlation between salivary uric acid levels and body fat percentages in teenagers, suggesting a reliable biomarker for early detection of chronic diseases. The study identified the level of uric acid in saliva as a good predictor of body fat percentage.
Researchers have developed a novel formulation that reduces the toxicity of crotoxin, a toxin from rattlesnake venom, and enhances its analgesic effect. In an animal model of neuropathic pain, the formulation demonstrated promising results, with longer-lasting analgesic effects compared to traditional treatments.
A novel simplified biotechnological route has been developed to convert sugarcane bagasse and wheat straw into fine chemicals. The new process uses a cascade of three catalytic enzymes to release ferulic acid from lignocellulosic biomass and convert it directly into coniferol, resulting in high conversion yields.
Researchers used high-resolution microcomputed tomography to study the anatomy of three known specimens of T. marauna, a Neotropical electric fish species. The study revealed characteristics of the fish's bones without requiring dissection, providing new insights into this rare species.
Researchers from Brazil, the UK, and Italy developed a novel palladium compound that acts selectively and powerfully against ovarian tumor cells without affecting healthy tissues. The compound has shown twice the potency of cisplatin against resistant tumor cells.
Researchers propose combining fever resistance with temporary tolerance promoted by controlled hypothermia for studying and treating severe conditions like sepsis. This innovative concept aims to understand human physiology's integrated defense strategies against infection.
Brazilian scientists led by Rodrigo Ramos Catharino found that Zika virus inhibits tumor cell proliferation in prostate cancer cells, even when inactivated. The study, supported by FAPESP, used a human prostate adenocarcinoma cell line and identified markers of metabolic changes caused by the virus.
Researchers found that smoked cannabis use impaired executive functions and increased the likelihood of relapse among cocaine addicts. The study suggests that harm reduction strategies using cannabis may not be effective in treating cocaine addiction.
Researchers identified secondary and tertiary fission clusters in young asteroid families formed by collision. The discovery challenges the long-held view that fission clusters and collisional families are distinct.
A team of Brazilian researchers has developed a technique to create functional mini-livers using human blood cells and 3D bioprinting. The innovation allows for the production of hepatic tissue in the laboratory in just 90 days, and may become an alternative to organ transplantation in the future.
Researchers have identified a genetic signature associated with the degree of pathological angiogenesis in breast cancer tumors. The study combined gene expression profiles from public databases with analysis of retinopathy models to uncover key genes involved in pathological angiogenesis, providing a new tool for breast cancer treatment.
Researchers found that the sympathetic nervous system can limit the generation of effector responses by inhibiting the action of cells attacking an antigen. This discovery opens up opportunities for novel therapies in autoimmune diseases like multiple sclerosis.
Leafcutter ants can predict adverse weather by sensing changes in atmospheric pressure, allowing them to collect and store the largest possible amount of food. Under low pressure, scouts leave the nest faster, increasing foraging efficiency and cutting more leaves.
Researchers discovered that Stenotrophomonas maltophilia uses a secretion system to inject toxins into competing bacteria, eliminating them. The study also identified a key toxin molecule that can reduce bacterial replication rates.
A study of six beaches in Brazil found a direct correlation between urbanization, metal contamination, and increased metabolic stress in mussels. The researchers suggest that this evidence should be used to inform public policy and mitigate the effects of human activities on marine ecosystems.
Researchers have mapped 373,869 genes in commercial sugarcane, achieving 99.1% genome coverage. This feat will facilitate genetic improvement of the world's largest crop to increase efficiency and productivity.
A Brazilian team at FAPESP-supported Center for Research on Inflammatory Diseases identified the strategy used by immune cells to combat the pathogen Mayaro virus. The study provides a basis for the development of drugs against this disease, targeting the NLRP3 inflammasome and its role in producing proinflammatory molecules.
A new study reveals an unusual diversity gradient in the Amazon Basin, with higher species richness in the western portion than expected. The research, led by scientists from France and Brazil, analyzed data from 97 subdrainage basins along the main stem of the Amazon and its tributaries.
A Brazilian consortium is working with international partners to develop new treatments for Malaria, Chagas disease and visceral leishmaniasis. The goal is to create a rapid-acting anti-malarial molecule that can eliminate the parasite without resistance development.
Brazilian researchers have reinterpreted the second law of thermodynamics by introducing statistical fluctuations, revealing that entropy can sometimes decrease. This study has practical interest for nanoscale machines and establishes a floor for fluctuations in thermodynamic quantities.
Despite increased use of mechanized harvesting, aerosol and ozone particle concentrations remain unchanged since the prohibition of burning sugarcane in 2002. The researcher suggests that greenhouse gas emissions and particulate matter come from other sources.
Researchers at UFABC in Brazil developed a glycerol fuel cell powered by niobium, promising to replace batteries in small devices and power electric vehicles. The technology reduces the need for fossil fuels and offers a sustainable energy solution.
International researchers have found that most of the black carbon transported to the Atlantic Ocean is 'young' and likely results from recent forest fires. The study, published in Nature Communications, used radiometric dating and molecular composition analysis to quantify and characterize the black carbon flowing in the Amazon River.
Researchers analyzed stable carbon and nitrogen isotopes in fur samples from 29 species of mammals to measure the impact of agriculture on their diet. The study found that herbivores and omnivores inhabiting forest fragments consumed agricultural resources, while carnivores close to croplands preyed on prey that feed on these resources.
The study estimates that preserving 270 million hectares of native vegetation yields Brazil USD 1.5 trillion per year in ecosystem services such as crop pollination, pest control, and water security. This research supports the importance of Legal Reserves and Permanent Conservation Areas in maintaining environmental services.
Physicists observe unusual quantum critical point in a heavy fermion compound, breaking the Kondo effect and exhibiting strange metal behavior. The discovery could lead to the creation of new sustainable materials for quantum information devices and superconductors.
A study by Brazilian researchers found that listening to instrumental music attenuates cardiac stress while driving, increasing parasympathetic nervous system activity and reducing sympathetic nervous system activation. This can contribute to the creation of cardiovascular preventative measures for situations of acute stress.
Researchers have discovered a critical point in supercooled water where thermal expansion and compressibility exhibit anomalous behavior. Theoretical model developed by Brazilian researchers can be applied to any system with two energy scales, including iron-based superconductors.
A new genetic mapping system for polyploid species has been developed in Brazil, allowing researchers to analyze the genes of complex organisms like sugarcane, kiwi, and blueberry. The open-source software package, MAPpoly, can be downloaded free of charge and has already been adopted by researchers at seven institutions worldwide.
Researchers at HUG-CELL identified a microRNA inhibitor that reduces tumor size and improves survival in mice with aggressive brain tumors. The synthetic miR-367 inhibitor prevents the regulation of proteins involved in cell growth, leading to an attenuation of tumor aggressiveness.
Researchers developed a novel method using quartz and feldspar grains from the Parnaíba River in Brazil's Northeast region. The analysis reveals significant differences in luminescence between samples from headwaters and lower reaches of the river, reflecting changes in precipitation patterns over the past 30,000 years.
Researchers found that the two species have complementary ecological functions, favoring seed dispersal and growth of adult trees. The loss of these herbivores could lead to significant effects on ecosystem dynamics, equivalent to the eradication of elephants from African and Asian forests.
Researchers in Brazil have successfully developed a modified strain of Uncaria guianensis, a medicinal plant native to the Amazon Rainforest. By modifying its alkaloid production using 'precursor-directed biosynthesis,' the team was able to create more potent chemicals with enhanced therapeutic effects.
A study of 993 Brazilian protected areas found 258 moderately vulnerable and 17 highly vulnerable to climate change. The Amazon and Atlantic Rainforest biomes are at greatest risk due to climate-driven changes in vegetation and native species distribution.
Brazilian researchers have discovered a new species of fungus gnat that emits blue light, which is the first record of such a species in the Neotropics. The larvae produce three lanterns and emit blue light, while adult insects do not.
A Brazilian study found that removing sugarcane straw could double fertilizer requirements by 2050 due to interrupted nutrient cycling. The researchers suggest leaving a substantial proportion of the straw on the ground to maintain soil health and productivity.
Researchers developed an injectable drug formulation using lipid nanoparticles to sustain the effect of naproxen in treating temporomandibular joint inflammation. The study showed significant reduction in inflammation and absence of side effects, making it a potential treatment option for this condition.
Researchers discovered that stingless bee larvae depend on a symbiotic relationship with three fungi species to develop and reach adulthood. The interaction between these fungi modulates larval development and highlights the importance of preserving this relationship against pesticide use.
A large group of ecologists contests an article proposing 'reforestation' of the Cerrado, Brazil's most biodiverse tropical savanna. The critics argue that the plan is based on flawed calculations and could worsen climate change by reducing surface albedo and intensifying global warming.
Researchers detected energy transfer from excited electrons to the crystal lattice on the femtosecond timescale, enabling the development of materials that retain energy for longer periods. This study contributes to the retardation of decoherence and the creation of quantum information devices such as optical switches.
Researchers have identified a novel compound that selectively inhibits the cyclin-dependent-like protein kinase PfCLK3 in Plasmodium falciparum, disrupting its lifecycle. The molecule TCMDC-135051 has shown promise in treating malaria and preventing transmission to vector insects.
Scientists discover a hitherto unknown mechanism behind the formation of nitroso thiols, important reaction products of nitric oxide. This process occurs during the formation of dinitrosyl iron complexes (DNICs), which are also products of nitric oxide.
A new composite material with enhanced antifungal activity was created by irradiating metallic tungstate with electrons and femtosecond laser pulses. The modified compound displayed antifungal activity 32 times greater than original silver tungstate, while also showing promise in treating bladder cancer cells.
Researchers identified a new species of parasite causing a disease similar to visceral leishmaniasis, resistant to current treatments. The parasite was found to infect both internal organs and skin, leading to severe symptoms and death in patients.
Researchers have discovered that a lipid produced by brown adipose tissue, called 12-HEPE, helps reduce blood sugar levels in obese mice. The study found that 12-HEPE promotes glucose uptake into both skeletal muscle and brown adipose tissue, leading to improved glucose tolerance.