A nationally representative study found that 1 in 5 US households have a parent-perceived mental health treatment need for their children. The study also revealed significant difficulties in accessing care, with 21.8% citing it as the reason for unmet needs.
A new study published in JAMA Network Open found that muscular strength is associated with lower mortality rates in women aged 63-99. Controlling for physical activity and other factors, researchers discovered a significant link between muscle mass and reduced mortality risk.
The study found increased requests for medication abortion among adolescents in states with gestational bans and parental consent requirements. Young adults also sought more medication abortion services post-Dobbs, with the highest demand in states with restrictive abortion laws.
A nationwide cohort study found that semaglutide initiators had a significantly higher risk of developing nonarteritic anterior ischemic optic neuropathy compared to sodium-glucose cotransporter-2 inhibitor initiators. The absolute risk was low, but clinicians and patients should be aware of this rare but evident increased risk.
Access to higher-level neonatal care is limited at rural birth hospitals, where less than 20% offer this care compared to 74% of urban hospitals. Urban birth hospitals are expanding higher-level neonatal care, exacerbating geographic disparities in access to care for high-risk infants.
A cohort study found that historically Black college or university attendance was associated with improved cognitive function compared to predominantly white institution attendance. The association held true for those attending college before and after legal racial segregation and discrimination in education.
Reducing air pollution levels may help delay and mitigate physical disability in aging adults, according to a new study published in JAMA Network Open. The findings suggest that lower air pollution levels are associated with slower progression of physical function limitations and disability.
A new study published in JAMA found that emergency department-initiated buprenorphine for opioid use disorder was well-tolerated and effective, with a low risk of withdrawal. The 7-day extended-release and sublingual buprenorphine groups showed similar treatment engagement rates on day 7.
The study found excess adiposity remained highly prevalent among US youths in 2024, with certain racial and ethnic subgroups affected more. The prevalence of severe obesity was also higher for these subgroups.
A cohort study found combined GLP-1RA and progestin therapy reduces endometrial cancer risk in women with benign uterine pathology or endometrial hyperplasia. The study suggests potential benefits of this treatment approach for nonmalignant uterine diseases.
A cross-sectional study investigates the effect of a smartwatch feature that alerts users about high blood pressure, impacting a significant portion of U.S. adults without diagnosed hypertension. The study reveals that nearly 1 in 5 participants received notifications and subsequently sought medical attention.
A study published in JAMA found that higher consumption of caffeinated coffee and tea is associated with a reduced risk of dementia. Moderate intake levels showed the most pronounced association, with better cognitive function also observed.
Research highlights increased mortality risks among individuals with autism spectrum disorder, intellectual disability, or cerebral palsy compared to the general population. The study's findings can inform public health strategies to address health disparities and excess mortality associated with developmental disabilities.
A meta-analysis of childhood food allergy risk factors reveals a combination of major and minor factors, including genetics and antibiotic exposure. The study provides insights into the complex interplay of these factors in the development of food allergies in infants and children.
A cross-sectional study of 4,043 registered nurses found that nonretired RNs are likely to return to work if hospitals address organizational issues driving them away. The top factors increasing their likelihood of returning were adequate staffing, flexible scheduling, and better wages or benefits.
Intravenous tenecteplase administered 4.5 to 24 hours after ischemic stroke non–large vessel occlusion improved functional outcomes at 90 days compared to standard care. However, it also increased the risk of symptomatic intracranial hemorrhage.
A recent cohort study found that individuals diagnosed with cancer in 2020 and 2021 experienced worse short-term survival rates compared to those diagnosed between 2015 and 2019. The study suggests substantial harms associated with cancer care disruptions during the COVID-19 pandemic.
A cohort study reveals that infants from vegan households have similar growth patterns to those from omnivorous households, with a higher risk of early underweight at birth. As the findings suggest, further research is needed to examine the quality of vegan diets and the impact of nutritional counseling during pregnancy and infancy.
Programs promoting equity, diversity, and inclusion initiatives in healthcare institutions are associated with an increased workforce. These programs support a more inclusive and equitable health care culture, according to the systematic review and meta-analysis.
A new study found semaglutide to be an effective treatment for preventing secondary cardiovascular disease in US adults. The medication meets conventional thresholds when used alone, but its cost-effectiveness is improved with combination therapy.
A ketogenic diet was found to have a modest effect in reducing depressive symptoms in patients with treatment-resistant depression. The study's results suggest that this dietary approach may be worth exploring as an adjunct therapy option.
A cohort study found a disproportionate increase in postpartum depression among women and adolescents in low-socioeconomic status communities following state abortion bans. The legislation disproportionately affects vulnerable populations, highlighting the need for targeted mental health support and policy interventions.
The study found that 2024-2025 COVID-19 vaccines offer protection against COVID-19 hospitalization and severe in-hospital outcomes. Monitoring vaccine effectiveness remains crucial to guide vaccine composition and recommendations.
A recent study found that respiratory syncytial virus (RSV) hospitalizations are associated with a higher risk of cardiorespiratory events, with some conditions experiencing elevated risks up to 180 days after admission. The findings highlight the importance of increasing RSV immunization in adults to mitigate this risk.
The study examines the characterization of the international-born health care workforce in rural US communities. It highlights the Conrad 30 waiver program, which enabled thousands of J-1 visa holders to remain in the US, caring for approximately 44 million patients, and H1-B visas as additional vehicles for immigrant clinicians.
A cross-sectional study found that up to half of adolescents in the US were using generative AI apps, while a small subset engaged in heavy use. The study highlights the need for future research on individual differences in GenAI use and its impacts on adolescent development.
US adults with uncontrolled blood pressure are often not taking antihypertensive medication, yet many have blood pressures within 10mmHg of the 2025 goal. Most adults with uncontrolled BP could achieve control through initiation of medication and lifestyle modification
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
A study published in JAMA found that salpingectomy significantly lowers the risk of developing tubo-ovarian carcinoma. The procedure, typically performed during unrelated pelvic or abdominal surgery, is now recommended as a preventive measure for eligible women.
A cohort study of 47,000 adults found that males had a 63% greater risk of all-cause mortality compared to females after adjusting for demographic and behavioral factors. The study suggests intrinsic biological factors, such as sex hormones or immune response, may contribute to these sex differences in mortality.
Non-Hispanic white births now constitute less than half of US births, while Hispanic births exceed one-fourth. These shifts reflect declining fertility across most groups, contrasted with immigration trends and younger ages among Hispanic women that sustain overall birth rates.
A cross-sectional analysis of nationwide population data reveals that high-deductible health plans are associated with worse overall and cancer-specific survival among cancer survivors. The study suggests that financial disincentives for medical care may lead to delayed or foregone necessary care, ultimately worsening cancer outcomes.
A recent study found that low-dose aspirin use was not associated with incident cancer incidence in older adults, contrary to previous findings. However, the study revealed a significant elevation in cancer mortality risk during the randomized clinical trial period, which did not persist after the trial ended.
Adverse experiences throughout life increase dementia and stroke risks, with depression as a mediating factor. Implementing life-course interventions addressing psychological trauma and mental health can reduce neurovascular disease burden.
The study analyzed US state-level adult obesity prevalence from 1990 to 2022, showing a significant increase to 42.5% by 2022 and forecasted to 46.9% by 2035. Disparities in obesity rates vary substantially by race and ethnicity.
Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) significantly lowers risks of limb events, cardiovascular events, all-cause mortality, and kidney disease progression compared to dipeptidyl peptidase-4 inhibitors in patients with diabetes. GLP-1 RAs are preferred for secondary prevention in this high-risk population.
A cohort study found that Medicaid expansion under the Affordable Care Act was associated with lower overall mortality among women with breast cancer aged 40-64. The benefits of expanded coverage were uneven, highlighting persistent disparities in healthcare access for certain populations.
A new study published in JAMA Network Open found that acupuncture is effective in reducing migraine without aura pain and improving functionality. The research identified specific brain network connections that predict treatment outcomes, enabling a personalized approach to pain management.
The JAMA Editorial Fellowship Program has selected ten new fellows, including physicians and nurses from diverse backgrounds, to learn about editorial decision-making and enhance scientific communication skills. Fellows will observe the peer-review process firsthand and bring their unique expertise to the table.
This study found that universal pre-kindergarten may help mitigate racial and ethnic disparities in child protective services involvement. Reductions in child neglect associated with UPK could benefit children's health and well-being in the short- and long-term.
A cohort study of St. Louis adults found that heightened cumulative lifespan stress and elevated inflammation were associated with shorter survival among Black participants. The findings highlight the need for policies addressing structural racism and treatments reducing inflammation to reduce mortality disparities.
A cohort study found that stronger family connections during adolescence can lead to improved social connections in adulthood. The study suggests that increasing family connection may help mitigate the effects of adult social disconnection.
After initiating GLP-1 receptor agonists, consumers showed a decrease in ultraprocessed foods and an increase in protein, while purchasing fewer calories, sugars, and saturated fats. These modest changes may have significant population-level effects given increasing GLP-1RA use.
Researchers found that an increasing number of preexisting maternal chronic conditions increases the risk of severe neonatal morbidity and mortality. Women with multiple chronic conditions may benefit from preconception counseling, earlier identification of complications, and enhanced newborn supports to optimize outcomes.
A randomized clinical trial found that a smart speaker-based intervention significantly improved mental distress, quality of life, and diabetes self-care among older adults with type 2 diabetes. This easily implemented self-management strategy may enhance health outcomes in this population.
Cancer mortality rates have decreased for breast cancer and leukemia, despite increasing incidence, while colorectal cancer has become the leading cause of death among US young adults. Colorectal cancer surpasses lung, breast, and prostate cancers as the leading cancer-related death in people under 50 years old.
Commercially insured patients frequently bypass rural hospitals between 2012 and 2021, generating large payments for receiving hospitals. The findings highlight the need for addressing this issue to alleviate financial distress on rural healthcare facilities.
A recent study published in JAMA Network Open found that abortion bans are associated with a significant increase in pregnancy-related mortality in the United States. The study suggests that restricting access to safe abortion care forces pregnant individuals to take on increased health risks, leading to higher mortality rates.
A systematic review and meta-analysis found a high prevalence of interpersonal violence globally among transgender and gender-diverse adults. The findings underscore the urgent need for evidence-based violence prevention and response strategies across settings to address this issue.
A recent survey study found a significant association between generative AI use and increased depressive symptoms in US adults. The magnitude of the effect varied by age group, suggesting that further research is needed to understand the causal relationship and underlying factors.