A new study published in PLOS Medicine found that undiagnosed Ebola virus infection was probably very rare among international healthcare workers deployed during the 2013-2015 outbreak. Despite asymptomatic cases occurring, no evidence of missed infections was found, but 'near miss' exposure incidents were common, putting frontline wor...
A global trial found that administering tranexamic acid within three hours of giving birth reduced death due to bleeding by 31%, with no side effects. The study also showed a significant reduction in the need for urgent surgery, saving up to 36% of mothers' lives.
The study found that the rotavirus vaccination programme resulted in a significant decrease in GP visits and hospital admissions for acute gastroenteritis, with an estimated 87,376 visits averted in England. This translates to an annual reduction of £12.5 million in healthcare costs.
A large randomized study found that Seasonal Malaria Chemoprevention (SMC) reduced malaria cases in children above 10 years of age by a quarter, demonstrating its potential to contribute to reducing transmission. The intervention also showed a high degree of protection with no severe side effects.
The European region is the most skeptical about vaccine safety, with seven countries ranking low in confidence. A global survey of nearly 66,000 people across 67 countries found that public trust in vaccines is precarious and influenced by concerns over side effects and scientific debates.
A third of young men and half of young women experience one or more sexual problems lasting at least three months, causing distress. Young people rarely seek professional help, instead relying on family, friends, or self-help sources.
A new study found that intense media coverage of the statins controversy led to a rise in patients stopping the treatment, with an 11% and 12% increase in existing users quitting statins for primary and secondary prevention. The study suggests that widespread reporting of debates can have a significant impact on patient behavior.
According to the National Gay Men's Sex Survey, more gay and bisexual men than ever are getting tested for HIV. However, one in four have never had an HIV test, and many are unsure of their status. The survey also found that condom use remains a concern, with one-in-three sexually active gay men having unprotected anal sex with non-ste...
A population-based study of nearly 6,000 people aged 60 and over found that Indian women who cook with biomass fuels were nearly 50% more likely to have visually impairing nuclear cataracts compared to those using clean fuels. The association was stronger for women cooking with longer duration of biomass fuels.
A new study published in the Journal of Public Health found that young gay and bisexual men in the UK are significantly at risk of poor mental health compared to their older counterparts. The research reveals that these men are six times more likely to attempt suicide or self-harm, as well as twice as likely to be depressed or anxious.
A new study found that a substantial proportion of women globally do not stay in health facilities long enough after giving birth, resulting in inadequate postnatal care. The average length of stay varies greatly across countries, with some women staying as little as 0.5 days or as long as 6.2 days.
A new study found that doses of deltamethrin can interfere with the development of malaria parasites in mosquitoes, reducing transmission. Insecticide-treated nets remain a vital tool in preventing malaria, even in areas with resistant mosquito populations.
Researchers have discovered two microRNAs, miR-155 and miR-184, that are directly related to the severity of inflammation in trachoma. The study found that increased expression of miR-155 and decreased expression of miR-184 are associated with higher levels of conjunctival inflammation.
New research highlights the slow progress made in preventing stillbirths, despite significant reductions in maternal and child deaths. The study reveals that most stillbirths are preventable with improved quality of care during labor and birth.
A new international collaboration has received a £2 million award to fund research into combatting cardiovascular disease in rural South Asia. The study will test low-cost strategies by health workers and doctors to lower blood pressure among adults and reduce their risk of heart disease.
A new study found that bariatric surgery can significantly improve type 2 diabetes and reduce high blood pressure. The procedure also prevents 80,000 cases of hypertension, 40,000 cases of type 2 diabetes, and 5,000 heart attacks over a four-year period.
Research suggests environmental changes are driving an increase in Plasmodium knowlesi malaria cases among people in Malaysia. Deforestation and land use changes are thought to be key drivers of the emergence of this disease, which is usually found only in monkeys.
A £5.7 million grant from the Biotechnology and Biological Sciences Research Council (BBSRC) will support the development of cheap and effective vaccines for poultry. The project aims to reduce infections in humans and minimize antibiotics in the food chain, with potential applications for cattle, sheep, and goats.
Researchers have uncovered the atomic-level structure of the bluetongue virus, providing a detailed understanding of its mechanism of entry into host cells. This breakthrough could lead to the development of more effective vaccines and treatments against this devastating disease.
A panel of global experts recommends 10 major reforms to strengthen the global system for outbreak prevention and response. The report highlights the need for improved governance, research data sharing, and rapid institutional responses to prevent future pandemics.
Researchers estimate that introducing Ebola treatment beds prevented an estimated 57,000 Ebola cases and 40,000 deaths in Sierra Leone. The study suggests that this could have been reduced further if the beds were introduced one month earlier.
Researchers at the London School of Hygiene & Tropical Medicine found Ixodes ricinus ticks in Richmond and Bushy parks, carrying the Borrelia burgdorferi bacterial pathogen that causes Lyme disease. The risk is low but caution is advised as most humans are infected through nymphs' bites.
A new study published in PLOS Medicine found that electronic reminders can significantly improve tuberculosis treatment adherence in China. Patients who received electronic medication monitors missed only 17% of their doses, compared to 29.9% for those with no reminders and 27.3% for those receiving text message reminders.
Child trafficking survivors experience poor mental health, self-harm, and suicide attempts, with 56% screening positive for depression and 15.8% reporting suicidal thoughts in the past month.
A study by the London School of Hygiene & Tropical Medicine found that health workers trained to use malaria rapid diagnostic tests (RDTs) still prescribe valuable malaria medicines to patients without testing for malaria. The researchers tested 5,000 participants across 40 communities and found that RDT use remained less than 50% desp...
A new study published in the Journal of Epidemiology and Community Health found that reducing street lighting at night does not lead to an increase in road traffic collisions or crime. Local authorities can safely reduce energy costs and carbon emissions by carefully assessing risks, according to the researchers.
A major re-analysis of a flagship study on deworming children has questioned the finding that it increases school attendance. The original trial reported improved attendance among untreated schools near treatment sites, but the new analysis found no evidence to support this claim.
A study published in PLOS ONE found that introducing rapid diagnostic tests in registered drug shops in Uganda reduced overdiagnosis of malaria by 73%, improving the use of valuable malaria drugs. The introduction of these tests improved treatment with artemisinin-based combination therapies, increasing appropriate treatment by 36%.
A new study published in PLOS Medicine suggests that taking diabetes medication glitazones may lower the risk of developing Parkinson's disease by 28%. Researchers analyzed data from over 160,000 diabetes patients and found a significant association between glitazone use and reduced incidence of Parkinson's.
A national initiative launched in 2007 to improve hip fracture care has led to substantial improvements in the use of early surgery and mortality rates among older people. The study, published in Medical Care journal, found a 7.6% annual relative reduction in 30-day mortality after the initiative's introduction.
Researchers found that standardized mortality ratios do not provide an accurate picture of how many deaths could have been avoided. Experts recommend alternative measures such as adherence to good practice guidelines and patient surveys to assess hospital quality.
A new study published in the American Journal of Clinical Nutrition found that vitamin B12 supplements offer no benefits for neurological or cognitive function in older people with moderate vitamin B12 deficiency. Researchers tested 201 participants aged over 75 years who received either a vitamin B12 supplement or a placebo, and found...
Living in areas with high road traffic noise may reduce life expectancy due to an increased risk of heart or blood vessel disease. Adults and the elderly living in noisy areas were found to be more likely to die from cardiovascular disease and experience strokes.
A new programme, Good School Toolkit, has successfully reduced physical violence from teachers against school children by 42% in Ugandan primary schools. The initiative aims to foster change in operational culture at the school level, leading to improved feelings of well-being and safety among students.
A mother's environment around the time of conception can affect her child's lifelong risk of disease by altering the function of a specific gene. The study found that maternal nutrition, particularly in rural Gambia, impacts the methylation marks on the VTRNA2-1 gene, which influences immunity and cancer risk.
Research suggests that gay and bisexual men in homophobic countries are less likely to know about HIV, use condoms, but face a higher potential risk of infection as technology increases access to sexual contact
A systematic review and meta-analysis of 90 studies found residents of modern homes were 47% less likely to be infected with malaria than those living in traditional houses. Modern housing features, such as closed eaves, ceilings, screened doors and windows, can block mosquitoes from entering homes and prevent transmission of the disease.
Researchers have identified two genetically divergent subpopulations of P. knowlesi in human cases, each associated with a different species of reservoir host. This discovery highlights the complexity of zoonotic malaria transmission and may lead to new possibilities for parasite adaptation to humans.
A new smartphone-based system called Peek has been shown to be as accurate as traditional charts in testing visual acuity. The app, designed by the London School of Hygiene & Tropical Medicine, uses a unique piece of hardware and software to test eyesight easily and affordably in community settings.
A new online tool called TB-Profiler can predict genetic resistance to tuberculosis drugs in a matter of minutes, improving the likelihood of cure for patients with drug-resistant TB. The tool uses genome sequence data to analyze and interpret resistance to 11 drugs used for treatment.
A study in Nigeria found that 9.3% of antimalarial drugs purchased in Enugu were of poor quality, while 1.2% were falsified and 6.8% substandard. The results highlight the need for improved drug regulation and monitoring to protect patients from receiving ineffective or harmful treatments.
A new study led by the London School of Hygiene & Tropical Medicine found that making realistic changes to UK diets could have substantial benefits for both health and the environment. The modified diet would contain fewer animal products, more fruit and vegetables, and less savoury snacks.
Researchers found no significant difference between treatment outcomes of patients using locally sourced and internationally quality-assured antibiotics. The study suggests that locally procured drugs can be a sustainable strategy, encouraging local pharmaceutical industries to adhere to quality standards.
A recent study by the London School of Hygiene & Tropical Medicine found a strong genetic component to how attractive individuals are to mosquitoes, linked to body odour. The research used identical and non-identical twin pairs to demonstrate this connection.
Researchers analyzed 2,028 antimalarials from Cambodia and Tanzania, finding no evidence of fake medicines, but substandard drugs were present in 31% of samples in Cambodia and 12% in Tanzania. The study highlights the importance of surveillance to protect patients and prevent drug resistance.
Researchers at London School of Hygiene & Tropical Medicine discovered a genetic mutation in the ap2mu gene that makes Plasmodium falciparum malaria parasites less susceptible to artemisinin and quinine. This finding suggests a different route to drug resistance may be developing independently in Africa.
Research found that parents are less likely to recognize their child's weight status accurately, especially if the child is from a deprived background or South Asian. The study highlights the need for measures to bridge the gap between parental perceptions and official guidelines.
A new study found that the majority of interventions under the deal are ineffective, poorly reported, or already underway. The deal aims to improve public health through voluntary pledges from industry and government.
A new global survey finds varying levels of vaccine hesitancy worldwide, with the UK and Nigeria showing high rates. Strategies to overcome challenges are crucial, as public confidence can severely undermine immunization programs.
Researchers have discovered a naturally occurring chemical, cedrol, that attracts pregnant malaria-transmitting mosquitoes, offering a new way to control mosquitoes. The team found that the chemical increased the likelihood of female mosquitoes laying eggs in treated water by two to three times.