Achieving target body temperature quickly is vital for patients with witnessed out-of-hospital cardiac arrest, leading to more favorable neurological outcomes. Extracorporeal cardiopulmonary resuscitation (ECPR) shows promise as a treatment option when combined with ECMO.
A standardized 'Artificial Pancreas (AP) Dashboard' is proposed to improve glycemic control and reduce hypoglycemia in insulin requiring patients with diabetes. The dashboard provides a single-page report of seven main components, including glucose metrics, insulin management, and user experience.
The Association of Cannabis Specialists (ACS) has named Cannabis and Cannabinoid Research their Official Journal, providing evidence-based education and standards for cannabis medicine. The journal aims to enhance clinical best practices, safeguard patient care, and advance cannabinoid research.
A new study proposes exposing students to community-based participatory methods, establishing action research groups for faculty, and broadening the definition of research impact to improve tenure promotion experiences for minority faculty. The goal is to combat systemic racism and increase diversity in environmental engineering programs.
The NIH Platform Vector Gene Therapy (PaVe-GT) project uses AAV9 as a platform vector to develop gene therapy products for four rare diseases. The project aims to improve the delivery of therapeutic genes into target cells, paving the way for access to gene therapy for patients with difficult-to-treat conditions.
Researchers identify blood biomarkers indicative of brain injury in COVID-19 patients, offering potential for timely diagnosis and cost-effective treatment approaches. The study highlights the increased risks of persistent neurological deficits, psychiatric disorders, and neurodegenerative diseases associated with COVID-19.
A study published in Facial Plastic Surgery & Aesthetic Medicine suggests that Zoom's increased usage has led to a rise in plastic surgery requests, particularly for nose and wrinkle treatments. The 'Zoom Dysmorphia' phenomenon is characterized by individuals seeking surgical interventions due to perceived flaws on video calls.
Recent studies report increased risk of rAAV mobilization in gene therapy, raising concerns for treated individuals and unintended populations. The research highlights the potential for rAAV vector production to replicate under certain conditions.
The AMADEE-18 Mars analog mission in Oman evaluated operational concepts and optimized strategies for future human missions. A benchmarking tool was developed to improve scientific output, mission safety, and efficiency.
Researchers found that inducing liver regeneration with thyroid hormone boosted CRISPR/Cas9-mediated gene correction, achieving 10.8% and 3.5% efficiency rates in neonatal and adult mice respectively. This discovery could lead to more efficient gene therapy for human diseases.
Military personnel with extensive occupational blast exposure showed significant differences in brain imaging measures, including increased cortical thickness and neural inflammation. The study provides insight into the functional and structural neuroimaging alterations occurring in this population.
The launch of Neurotrauma Reports Null Hypothesis journal aims to promote balance in academic publications by publishing well-performed replication and negative studies. The initiative encourages researchers, funders, and publishers to report on important negative results with the same priority as positive results.
The CRISPR Journal announces its October 2020 issue, featuring expert reactions to the National Academies' Heritable Human Genome Editing report. The journal also presents a comprehensive survey of global laws and regulations on hereditary human genome editing, highlighting both countries that prohibit and permit such research.
Mary Ann Liebert, Inc. will publish Journal of Correctional Health Care, a national, peer-reviewed journal focusing on correctional health care. The journal provides education for healthcare providers serving the incarcerated population, covering topics such as clinical care, mental health, and substance abuse treatment.
Researchers found that a modified bentonite complex can remove 17α-ethinylestradiol and other pharmaceutical organic micropollutants from wastewater environments. The study demonstrates an effective and cost-efficient method for removing synthetic estrogen from bodies of water.
A special issue of Population Health Management explores data-driven approaches to combatting COVID-19. The journal highlights the need for population health tools to successfully tackle emerging health crises, with expert insights from major companies and organizations.
A genotype-agnostic gene therapy for cystic fibrosis has shown promise in clinical trials, potentially treating the disease in any patient, independent of their underlying mutation. Challenges remain to be overcome, including developing effective drug delivery systems that can reach pulmonary epithelial cells at low doses.
A new article offers practical guidance on avoiding ableist language in autism research, which can lead to stigmatization and exclusion of autistic individuals. The authors aim to reduce misunderstanding and improve communication by providing researchers with tools to use more inclusive language.
A special issue on Integrative Palliative Care was published in JACM, featuring research from 11 countries on this new model of care. The issue highlights the potential value of greater mutual respect and exploratory collaborations between palliative medicine and integrative health communities.
A new Expert Panel Discussion examines the status of blood-based biomarker development and point-of-care testing for concussion diagnosis. The discussion highlights the potential benefits of specific biomarkers in detecting brain trauma masked by other injuries or symptoms, adding value over current clinical methods.
Researchers discovered a link between gene mutations in SCN2B and SCN4B genes and cardiac arrhythmias. The study sheds light on the role of sodium V channels in maintaining heart function and may lead to new treatments for cardiac syndromes.
New technologies are solving cold cases using DNA sequencing, robotics, and automation. Forensic genomics has made significant progress in recent years, enabling the solution of an unprecedented number of cold cases, including homicides and other violent crimes.
Researchers successfully used gene therapy to overcome cardiac effects of Friedreich's ataxia in a mouse model, achieving exercise performance similar to healthy littermates. The treatment delivered the frataxin gene via adeno-associated virus (AAV) and showed promising results.
A novel taxonomic approach is introduced to break down and reaggregate study specifics, enabling a determination of effective obesity intervention strategies. The research was supported by the NIH under contract number GS-00F-0007M.
Researchers developed a point-of-care GFAP assay that delivers results in minutes, outperforming the current FDA-cleared assay. The assay's diagnostic performance was significantly better than that of the S100B biomarker, validating its utility as a diagnostic marker for CT-detected lesions.
A study found that nearly 16% of LGBT adults in California own a gun or live with one, often for protection. This increases their likelihood of victimization, including suicide. The research highlights the need for unique gun violence prevention strategies targeting the LGBT community.
A meta-analysis of NHP studies reveals that AAV gene therapy often causes DRG pathology with no clinical effects, prompting preclinical safety evaluations before clinical trials. The study's findings have the potential to streamline the development process for new vectors.
A Commentary in AIDS Patient Care and STDs finds COVID-19 and HIV diagnoses decreasing as white population increases in US counties. Systemic racism is a key factor contributing to disparities in health outcomes among communities of color.
A study published in Population Health Management found that socially isolated elderly individuals are more likely to experience future hospital admissions and emergency room visits. The research highlights the importance of providing support services to prevent unnecessary healthcare utilization.
Researchers developed novel variants of adeno-associated viral (AAV) capsids with improved transduction properties in the mouse retina and cornea. The efficient gene delivery of these variants was confirmed in non-human primate tissue, adding to their potential use in treating human ocular diseases.
A first-in-human study found that MRG-110 significantly reduced miR-92a levels in healthy humans after a single intravenous dose. This inhibition has shown beneficial effects in animal models, including improved vascularization after myocardial infarction and accelerated wound healing.
A breakthrough study using gene therapy to target the inner retina has prevented blindness in a mouse model of CLN3 Batten disease. The treatment led to significant survival of bipolar cells and preserved retinal function, according to researchers.
Recent reports suggest a lower incidence of COVID-19 among high-altitude populations, however, current data is insufficient to confirm this association. The authors conclude that there is currently little supporting evidence for any protective benefit of genetic or nongenomic adaptation to high-altitude hypoxia.
The Journal of ABSA International has been awarded to Mary Ann Liebert, Inc., effective 2021. The publication aims to promote global biosafety awareness and best practices in preventing occupational exposures and adverse environmental impacts related to biohazardous releases.
Researchers found potential benefits of meditation and yoga in reducing stress and inflammation, which can aid in immune system enhancement. These practices may provide additional counteracting effects against certain infectious challenges associated with COVID-19.
A recent report of two children's deaths in a gene therapy trial for X-linked myotubular myopathy has sparked concerns over the safety of gene therapy vectors. The editorial emphasizes the need for iterative development and cooperation among scientists to ensure safe and effective treatments for rare genetic diseases.
Telemedicine Reports will publish articles on telemedicine and telehealth advancements, offering innovative solutions for practitioners and medical centers. The journal will provide a dedicated forum for authors to share research, reviews, and practical solutions.
The COVID-19 pandemic is having a disproportionate impact on environmental justice communities, who are already vulnerable to poor air and water quality, limited access to healthcare, and socioeconomic hardship. These disparities in health outcomes and mortality rates highlight the need for urgent attention and policy changes.
A new protocol has been established to guide clinicians in delivering optimal care to women with breast cancer who are breastfeeding. The protocol addresses the spectrum of care, including oncologic breast surgery, chemotherapy, and adjuvant therapy, while emphasizing the importance of breastfeeding for these mothers.
A commentary article exposes COVID-19 conspiracy theories linked to Dr. Judy Mikovits' fraudulent research, highlighting the dangers of such misinformation. The journal AIDS Research and Human Retroviruses has spoken out against the spread of false information on social media platforms.
Autistic burnout is a chronic state of exhaustion, loss of skills, and reduced tolerance to stimulus caused by chronic life stress and inadequate supports. Research highlights the need for understanding, relieving, and preventing autistic burnout to improve health, quality of life, and independent living.
Clinical trials of COVID-19 treatments have left pregnant and breastfeeding women without safety data, forcing a difficult decision between medication use and breastfeeding. The lack of research on drug transfer into breast milk poses a risk to infants.
Researchers found that virtual care did not negatively impact glycemic outcomes for diabetes patients, improving hospital exposure and transmission risk. The study's results have broader implications for telehealth implementation in remote locations.
The new peer-reviewed journal Forensic Genomics will document advances in genetic testing and genome sequencing to support human identification. The Journal will accept original research papers and genealogical research on DNA testing technologies, algorithms, artificial intelligence, and genealogical methods.
The COVID-19 pandemic has worsened health inequities among vulnerable populations, with increased racial and ethnic biases impacting healthcare decisions. Remote diagnosis and care technology access also affects patient outcomes.
A new study found that telehealth monitoring and technology can lead to better outcomes for patients with type 1 diabetes during the COVID-19 pandemic. By allowing for frequent insulin dose adjustments and improving glucose values, telehealth helped avoid hospital admissions for diabetic ketoacidosis.
A new paper identifies urgent issues to consider, including potential animal-to-human transmission, food security concerns, and national security threats if military service dogs are infected. Stringent studies are needed to understand the risks posed by domestic animals as a possible source for human infection.
A new study characterizes two sisters with exceptional longevity, revealing increased resistance to age-related diseases. The research suggests that supercentenarians can approach the limits of their functional human reserve, avoiding acute causes of death.
A new study revealed that 42.8% of medical staff treated COVID-19 patients experienced serious skin injuries related to personal protective equipment (PPE) use. The most common types of skin injuries were device-related pressure injuries, moist associated skin damage, and skin tears.
Neurotrauma Reports is a peer-reviewed open access journal publishing research on traumatic brain and spinal cord injury. The journal aims to provide a dedicated forum for the neurotrauma field, including original papers, review articles, and studies on regional scope or patient populations.