Researchers discovered a new combination of treatments that may benefit patients with certain gene mutations. Inhibiting the protein AKT suppressed growth of tumour cells in animal models, while combining dexamethasone with AKT inhibition showed better results.
Researchers have demonstrated improvements in the fatigue life of high strength aluminium alloys by 25 times, a significant outcome for the global transport industry. Aluminium alloy microstructures that can heal weak links called 'precipitate free zones' (PFZs) were created to enhance fatigue performance.
Researchers at Monash University have discovered how volcanoes experience stress, which can lead to collapse and eruptions. By studying a dormant volcano on La Palma, the team found that repeated movement of magma inside the volcano causes it to become 'stressed' and potentially unstable.
A Monash University study warns of devastating impacts of climate change on wildfire seasons, with fuel, oxygen, and ignition source conditions fueling the crisis. Immediate action is needed to limit greenhouse gas emissions and avoid substantial increases in wildfire exposure by the end of the century.
Researchers at Monash University discovered that metformin, a diabetes drug, removes damaged proteins and restores swimming ability in zebrafish with myofibrillar myopathies. The treatment shows promise for children suffering from this rare genetic disease.
A new discovery in regenerative medicine may lead to new treatments for placenta complications during pregnancy. Researchers at Monash University and Duke-NUS have developed a method to create induced trophoblast stem cells (iTSCs) that can be used to make placenta cells.
A collaborative study has uncovered new markers uniquely present on melanoma tumours that can be recognised by the immune system. These markers, known as spliced peptides, can be used to develop therapeutic vaccines to combat melanoma.
Researchers have developed an immune-oncology approach that uses nanobodies to target cancer cells and boost the body's natural immune response. The new therapy has shown promise in treating multiple myeloma and acute myeloid leukemia, and could lead to new treatments for a range of cancers.
A comprehensive international study found that pregnancy can delay the onset of multiple sclerosis (MS) by more than 3 years. The study used a global database of over 70,000 MS patients and suggested that pregnancy may reduce abnormal immune system activity that causes MS.
Researchers at Monash University developed a machine-learning algorithm that can characterise graphene properties and quality without bias in under 14 minutes. This technology will help manufacturers boost the quality and reliability of their graphene supply, saving time and money.
Researchers at Monash University have discovered a previously unknown way bacteria evade immune responses, targeting mitochondria for disarming. The study suggests potential new ways to combat resistant bacterial infections and could lead to new therapeutic possibilities.
A global research team has developed a new adsorbent-based desalination process that uses sunlight to regenerate metal-organic frameworks (MOFs), producing clean drinking water in under 30 minutes. The technology filters harmful particles and achieves a TDS of <500 ppm, making it suitable for millions of people globally.
A world-first study found altered gut bacteria in people with Huntington's disease, associated with symptoms and disease progression. The research raises the possibility of targeting gut bacteria for future treatment.
A study published in Nature Communications reveals the intricate choreography of phage assembly and its impact on bacterial infections. The research provides new insights into the mechanism of action of phages, which could lead to more precise and effective treatments for drug-resistant bacterial infections.
The review paper reveals the intricacies of bacterial organelles, which support functions essential for survival and growth. Organelles enable bacteria to perform extraordinary tasks, such as photosynthesis and orientation relative to magnetic fields.
Researchers discovered a rare single gene mutation in a patient that eliminated an immune cell population, namely MAIT cells. The study demonstrates the impact of a single gene mutation on the human immune system and advances personalized medicine.
Monash researchers have developed a drug that can prevent blood clots from forming, which are the primary cause of heart attacks and strokes. The drug has shown promising results in animal models and human cells, suggesting it could be a game-changer in cardiovascular disease treatment.
A strong cellular lining is essential for a healthy gut, and damage to it can cause painful symptoms. Monash University researchers have identified a key biomolecule, Neuregulin-1, that accelerates the repair of damaged tissue by prompting stem cells to regenerate.
Researchers developed a simple agglutination assay to detect COVID-19 antibodies in plasma samples within 20 minutes. This test can identify recent cases and aid clinical trials, with potential for widespread use in high-risk countries.
A team of researchers has quantified human activity across Antarctica, revealing that almost every area has been visited. Biodiversity is not well-represented within these areas, highlighting the need for swift action to declare new protected areas.
Researchers have developed a radical non-invasive X-ray technology that can pinpoint localised areas of deficiency in lungs, improving diagnoses and treatments for cystic fibrosis. The technology, called X-ray velocimetry, measures airflow through the lungs during breathing cycles, enabling better assessment of lung function.
A study published in Neurology suggests that at least one million Chinese people with epilepsy could be candidates for a standard operation to leave them seizure-free. The study found 108 patients with lesions that could potentially be cured by surgery, with a high success rate of around 70-80%.
A recent study by Monash University suggests that components within vaccines can play a major role in aiding the lifespan of individual plasma cells. This understanding could lead to the development of more effective vaccines.
The study found that C. difficile massively activates a human enzyme called plasminogen to destroy gut tissue and spread infection. Researchers developed an antibody that prevents plasminogen activation, stalling infection progress and tissue damage.
A landmark Australian study found even low levels of PM2.5, fine particulate matter in air pollution, increase risk of death from cardiovascular and respiratory diseases. For every 1 ug/m3 increase, there is a 2% increased risk of early death, threatening WHO safety standards.
Researchers at Monash University have discovered that reducing two essential amino acids, threonine and tryptophan, can lead to increased calorie burn and improved health in young mice. A low-threonine diet also protected obese mice from developing type 2 diabetes.
Researchers created an ultrathin membrane with high porosity that can filter potentially harmful ions from water. The membrane has potential to deliver clean water for millions of people globally through purification and desalination processes.
Researchers found that T cells increase their metabolism to survive, contradicting previous assumptions about immune function. The study suggests that targeted interventions like vaccines or immunotherapies could boost T cell immunity in the elderly.
Researchers from Monash University and CSIRO have developed a magnetized Metal Organic Frameworks (MOFs) nanocomposite that captures carbon dioxide with remarkable speed and low energy cost. This technology is 45% more efficient than commercially deployed materials, making it a promising solution for emissions reduction and renewable e...
Researchers observed an accreting neutron star entering an outburst phase, studying its structure and material movement. The observation revealed a 12-day process, contradicting previous theories of two- to three-day timescales.
Researchers from Monash, Swinburne and RMIT universities recorded Australia's fastest internet data speed and the world's from a single optical chip, capable of supporting 1.8 million households' high-speed connections. The technology has the potential to scale up existing infrastructure and enable ultra-high speed communications.
A Monash University study found that inhibiting cell death pathways in oocytes allows them to rapidly repair DNA damage, maintaining fertility. Double-strand breaks are the most harmful type of DNA damage, promoting genetic instability if not repaired correctly.
Researchers at Monash University have made a significant breakthrough in the development of new glycopeptide antibiotics, which could provide a vital advantage in the fight against resistant bacteria. By combining natural enzymes with synthetic chemistry, scientists can now explore new antibiotics that have never been made before.
A world-first study led by Monash University demonstrates significant benefits to premature babies' heart and brain function when held by parents in skin-to-skin contact. One hour a day of kangaroo care significantly improved blood flow to the brain and cardiac function, compared to measurements done while in the incubator.
A stranded seal was found with multiple facial wounds inflicted by fish, which researchers attribute to the animal's attempt to defend itself. The study suggests that similar injuries may be more common than previously thought, highlighting the dangers faced by marine mammals in their quest for food.
Researchers from Monash University and The Royal Women's Hospital developed a ventilator splitting method that can be used with standard hospital equipment to address the global ventilator shortage. The study, published in Anaesthesia, found that by modifying air pressure, flow, and volume, two lungs of different compliances can be ven...
A twin study conducted by Monash University researchers found that even low levels of air pollution can affect gene expression, leading to long-term health consequences. The study suggests exposure to air pollutants, even at low levels, has real-life implications for the current COVID pandemic.
Researchers at Monash University have discovered the mechanism behind one of two signalling arms involved in the cGAS-STING pathway. The findings reveal that a closely related TBK1 homologue, IKK-epsilon, plays a crucial role in cytokine production, leading to new understanding of autoimmune diseases and cancer treatment.
Monash University researchers have identified an anti-parasitic drug, Ivermectin, as a potential treatment for COVID-19. The study found that a single dose of the drug can stop the SARS-CoV-2 virus from growing in cell culture within 48 hours.
Researchers in Australia have developed a new ultrasound biosensor that can be used to track disease states in real-time, using cheap and portable technology. The sensor uses nanoparticles that alter their stiffness in response to pH changes, allowing for accurate monitoring of biomarkers such as tumor shrinkage and organ response.
A bacterial superbug can prevent stem cells in the gut from regenerating the inner lining of the intestine, causing potentially severe disease. This damage impairs tissue repair and recovery from disease, particularly in older adults.
Monash University researchers improved aluminum alloy design by introducing specific crystal defects, enabling rapid nucleation of a strengthening phase. The study's findings have implications for lightweight alloys used in the aerospace industry.
A world-first study has patented a new filtration technique that can filter lithium ions in an ultra-fast and highly selective manner. The technology, developed by Monash University, has shown a lithium recovery rate of approximately 90 percent, a substantial improvement on the current solar evaporation process.
A new study reveals half of young Australian women experience sexually-related personal distress, with 20.6% experiencing at least one female sexual dysfunction. Low self-image and psychotropic medication are major contributors to these issues.
Researchers at Monash University have developed a new technology to visualize airflow in the lungs, enabling faster and more accurate diagnoses. The technology can pinpoint localized areas of deficiency and has potential for treating respiratory illnesses earlier.
Researchers at Monash University have discovered a key mechanism that enables hookworms to evade the human immune system. By understanding how these parasites destroy neutrophil extracellular traps, scientists may be able to develop vaccines to boost immunity and prevent reinfection.
A team of scientists at Monash University has successfully created dynamic covalent oligomers that mimic the combination of complementary DNA strands. This breakthrough could lead to improved nanostructures for solar capture technology and molecular electronics, as well as enhanced interfaces between prostheses and human tissue.
Wild grey seals can clap their flippers underwater during breeding season, using the loud high-frequency noise to warn off competitors and advertise themselves to potential mates. This unique form of communication may help protect the species from human noise pollution.
Researchers at Monash University developed a wearable device using continuous wave radar and photoplethysmogram sensors to calculate continuous blood pressure measurements. The device achieved high accuracy rates, with 93% success during sedentary tasks and 83% during exercises.
A recent global trial has found that high-dose intravenous vitamin C, thiamine, and hydrocortisone therapy does not improve survival rates or treatment outcomes for patients with sepsis. The study refutes previous claims of the effectiveness of this 'Vitamin C cocktail' in treating sepsis.