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Monash University


Monash University researchers unlock the key that could lead to the development of non-opioid painkillers to treat chronic pain

Researchers at Monash University have discovered a new mode of targeting the adenosine A1 receptor protein, which could lead to the development of non-opioid painkillers to treat chronic neuropathic pain. The study provides an opportunity for researchers to develop safer and more effective drugs.

SourceMonash University·JournalNature·TypeExperimental study·DateSep 8, 2021

New study in regenerative medicine identifies RNA released from damaged cells act as the signal to initiate repair after injury

A new study from Monash University has identified RNA released from damaged cells as a signal to initiate repair in the nervous system. The research found that blocking or enhancing this recruitment of immature neurons halted or sped up neural circuit recovery, demonstrating their power in boosting neural repair.

SourceMonash University·JournalDevelopmental Cell·TypeExperimental study·DateAug 23, 2021

Patients helping researchers to advance treatments for prostate cancer

Monash University researchers have established a vast collection of living prostate cancer tumors from patients, enabling the testing of new treatments and advancing patient care. The PDX collection comprises 59 tumors collected from 30 patients between 2012-2020, providing a unique resource for scientists and pharmaceutical companies.

SourceMonash University·JournalNature Communications·TypeExperimental study·DateAug 19, 2021

HPV vaccine shows success in gay, bisexual men

A study by Monash University found a significant reduction in all four HPV genotypes in gay/bisexual men after implementing the school-based HPV vaccination program. The results suggest that male vaccination may lead to a potential reduction in anal cancer among gay and bisexual men in Australia.

SourceMonash University·JournalThe Lancet Infectious Diseases·DateMay 25, 2021

Scientists rewrite the genesis of mosquito-borne viruses

Researchers have discovered a misinterpreted model of immature flavivirus particles, revealing an unexpected organisation that could lead to new and better vaccines. The study's findings define the exact wiring of the immature virus before it becomes infectious, providing a solid foundation for designing tomorrow's treatments.

SourceMonash University·JournalScience Advances·DateMay 14, 2021

Monash study may help boost peptide design

Scientists have discovered a crucial aspect of peptide machinery, providing a breakthrough in re-engineering peptides. The study sheds light on how selectivity is achieved in the assembly lines that produce peptides, enabling single amino acid changes without altering multiple components.

SourceMonash University·JournalNature Communications·DateMay 10, 2021

Dexamethasone treatment safe in surgery

A large clinical trial has definitively shown that dexamethasone, a steroid commonly used during anaesthesia before surgery, does not increase the risk of surgical wound infections. The study enrolled over 8,700 patients and found no significant difference in wound infection rates between those receiving dexamethasone and placebo.

SourceMonash University·JournalNew England Journal of Medicine·DateMay 5, 2021

Researchers find a way to mend a broken heart

A Monash University study has discovered a way to prevent and reverse the damage caused by broken-heart syndrome, also known as Takotsubo cardiomyopathy. The breakthrough uses Suberanilohydroxamic acid to target genes and improve cardiac health.

SourceMonash University·JournalSignal Transduction and Targeted Therapy·DateApr 19, 2021

Researchers discover how animals grow their pointy body parts

An interdisciplinary team at Monash University discovered a new universal rule of biological growth that explains surprising similarities in the shapes of sharp structures across the tree of life. The 'power cascade' rule applies to various animals, including teeth, horns, claws, and even plant thorns, following a power law pattern.

SourceMonash University·JournalBMC Biology·DateMar 29, 2021

Discovery of a third T cell lineage

Researchers at Monash University have identified a novel T cell lineage, γμ T cells, which use a unique antibody-like structure to recognize pathogens. This discovery expands the immunology 'toolbox' and may lead to new approaches for fighting viral infections such as COVID-19.

SourceMonash University·JournalScience·DateMar 25, 2021

Ice loss likely to continue in Antarctica

A new international study by Monash University reveals that Antarctica's ice loss is expected to continue unabated for a long time, even if climate change is brought under control. The study found that rapid ice loss rates in the recent geological past were similar to those observed in rapidly changing parts of Antarctica today.

SourceMonash University·JournalGeology·DateOct 21, 2020