A Princeton-led team has created a new measure called the influence score, which can effectively differentiate between noisy and predictive variables in big data. This approach significantly improves prediction rates in various fields, including breast cancer diagnosis, terrorism, and financial markets.
Princeton University researchers have developed a new model that creates a 'perfect glass' that never crystallizes, even at absolute zero. The model considers 2-, 3-, and 4-body interactions to suppress crystallization, revealing unique properties of perfect glasses.
Measles can spread quickly in schools, with one infected child potentially infecting up to 27 others on average. High vaccination rates are necessary to prevent transmission, and historical data from a 1904 outbreak supports this finding.
A Princeton-led study explores how people form impressions from facial appearances, finding that exposure to different faces influences what is perceived as typical and evaluates positively. The results suggest that social meaning is imbued in faces based on their statistical position relative to an individual's learned central tendency.
Researchers at Princeton University developed a method called Knockout Sudoku, which quickly and affordably creates whole-genome knockout collections. This allows for the exploration of genetics outside of model organisms, making it a powerful tool for advancing genetic research.
A new study confirms that the coral-algae symbiotic relationship dates back to the late Triassic period, around 210 million years ago. This finding highlights the importance of symbiosis for the health and development of coral reefs, which provide habitat for a quarter of all marine life.
Electron orbits are directly visualized in a high-magnetic field, showing a quantum fluid state with unique elliptical paths. The discovery could inspire new electronics technologies, particularly in valleytronics and two-dimensional materials.
A team of researchers at Princeton University has devised a novel pathway for reactivity that bypasses the need for reactive functional groups. The method uses proton-coupled electron transfer to form valuable carbon-carbon bonds, opening up new synthetic opportunities.
Researchers have compiled a 30-year data set to construct the first ice core-based record of atmospheric oxygen concentrations spanning 800,000 years. The study shows that atmospheric oxygen has declined by 0.7 percent relative to current concentrations, primarily due to fossil fuel burning.
Researchers analyze data from a survey of Gulf Coast residents to understand how their perceptions of hurricane threat vary depending on their gender, belief in climate change, and recent experience. The study found that those who have recently experienced severe hurricanes are more likely to perceive the increasing violence of storms.
Climate change contributes to severe algal blooms in the Chesapeake Bay through increased precipitation variability. Nitrogen-rich agricultural runoff, exacerbated by changing weather patterns, leads to toxic algae growth and hypoxia, harming humans, marine life, and fisheries.
A team of Princeton researchers has developed a machine-learning approach that analyzes the entire human genome to predict which genes may cause autism spectrum disorder. By identifying 2,500 potential autism genes, this new method provides a significant breakthrough in understanding the genetic basis of autism.
Researchers at Princeton University have developed a new method to transform individual selfies by adjusting angles and distances, creating more realistic portraits. The tool can also alter poses and generate 3-D head shots, with potential applications including 'live' photos that seem to move uncannily.
Researchers propose that women in Zika-affected countries can safely conceive during the 'trough' of low mosquito activity, reducing the risk of birth defects. This approach could prevent thousands of cases per year, especially in Brazil and Puerto Rico.
Researchers found that eastern and red wolves are not evolutionarily distinct species but a hybrid of gray wolf and coyote ancestry. The study concludes that the ESA should protect hybrid species due to common interbreeding in the wild, which may not be harmful.
Research by Princeton University found that ADHD medication can reduce risks such as sexually transmitted diseases, substance abuse, and injuries in children and teens. The study analyzed Medicaid claims of nearly 150,000 children with ADHD in South Carolina between 2003 and 2013.
The study found that genetic signatures predict education, height, BMI, and heart disease more strongly today than in the past. The role of genes decreased for education but increased for BMI and heart disease due to environmental factors.
An international team predicts several new types of quantum particles in materials, distinguished by intrinsic properties such as responses to magnetic and electric fields. The researchers propose that these fermions can appear in the bulk of materials, enabling a more systematic way to determine whether a system is a protected metal.
Enhancers can increase the frequency of gene activity bursts, suggesting these bursts may be critical for genetic regulation. The study found that enhancer location and strength influence bursting frequencies.
Researchers at Princeton University, MIT and Merck & Co. have developed a cheap, complementary approach to the fundamental chemical reaction known as C-N bond coupling. The direct, cost-effective method enables efficient production of anilines, a common structure in medicinal agents, without expensive ligands.
Scientists at Princeton University have found a common underlying connection between diverse materials exhibiting extreme magnetoresistance. This property could be useful for developing new types of magnetic memory devices.
Researchers found that repairing mutated cilia genes restored cerebrospinal fluid flow and prevented spinal curves from developing in zebrafish. If translatable to humans, the study could lead to a non-surgical approach for treating idiopathic scoliosis.
Researchers at Princeton University have revealed new insights into the mechanism of phenylalanine hydroxylase, a critical liver enzyme for human health. By applying unique approaches combining small-angle x-ray scattering and chromatography, they provided evidence for a model of the active structure of the enzyme.
Theoretical chemists at Princeton University developed operational dynamic modeling (ODM), a new approach to model quantum friction, which satisfies both the Heisenberg Uncertainty Principle and produces real observations. This breakthrough opens a way forward to understand not only quantum friction but also other dissipative phenomena.
A new method combines structured expert judgment and probabilistic inversion to provide a single, consistent set of probabilities for future sea-level rise. This approach aims to address the lack of formality in evaluating climate model uncertainty, which can impact policy and preparedness.
Princeton University researchers used advanced techniques to record dopamine neuron activity in the striatum, finding that these neurons not only encode reward but also directly control movements. This discovery challenges current understanding of dopamine's role in movement-related disorders like Parkinson's disease.
A specific gene, HMGA2, has been identified as the key to the evolution of smaller beaks in medium ground finches in response to a drought-induced food shortage. The researchers found that the gene comes in two forms, with one dominant in birds with small beaks and the other in those with large beaks.
A new study suggests that tighter border enforcement along the US-Mexico border has led to an increase in undocumented population growth, despite spending $35 billion on security measures. The research found that greater enforcement raised costs and risks for migrants, causing them to stay longer in the US.
Phytoplankton can spread globally in under a decade, while pollution can become a problem within years. The study's model, using Dijkstra's algorithm, confirmed travel times for real-world objects like plastic debris and radioactive particles.
A team of researchers identified traits that best protect trees against death from drought, finding that xylem stress is a key predictor of survival. The study provides a foundation for improving predictions of drought-induced tree mortality across diverse forests.
Researchers track NADPH production through a novel pathway, revealing an environmental-dependent switch between two recognized routes. The findings have implications for diseases such as cancer and diabetes, highlighting the importance of understanding NADPH pathways in cellular processes.
A team of researchers at Princeton University has predicted the existence of a new state of matter where current flows through surface channels resembling an hourglass. The hourglass fermion is created by tuning a property of the material, allowing for efficient transistor switching and potential applications.
A new reaction method produces highly useful 1,2-dihydropyridines through a selective route, utilizing pyridine as an inexpensive and abundant substrate. The direct cross-coupling reaction employs a chiral nickel catalyst and activating agent to couple nucleophilic arenes with pyridine.
Researchers observed electrons sinking into crystal depths via special channels, unlike standard materials. The study's results suggest a better understanding of topological materials could lead to faster electronic devices.
Researchers at Princeton University discovered how a synthetic protein called SynSerB promotes cell growth in serine-depleted E. coli cells. By inducing overexpression of a protein called HisB, SynSerB enables the production of essential amino acid serine, allowing cells to survive.
Researchers discovered that Kurly protein is required for proper cilia movement and orientation, crucial for fluid flow and organ development. The study highlights the importance of Kurly in understanding human diseases such as polycystic kidney disease and left-right patterning disorders.
Researchers at Princeton University have discovered the two-step process that activates Suv39h1, an essential enzyme responsible for organizing large portions of human DNA. The study reveals how the enzyme employs a positive feedback loop to chemically tag unnecessary regions of DNA.
Researchers from Princeton University will present on the intersection of citizen science and technology, exploring its potential to tackle environmental challenges. Additionally, they will discuss the complexities of measles control in resource-poor settings, highlighting the need for targeted interventions and statistical analysis.
Researchers at Princeton University discovered the mode of action of antibiotic tropodithietic acid (TDA), revealing its ability to kill cancer cells. TDA's unique mechanism involves disrupting cell membrane function, rendering it a potential anticancer agent.
Two studies find gamma ray signals in the galactic center are unlikely caused by dark matter collisions. Instead, they could be attributed to fast-rotating stars called millisecond pulsars. Researchers used statistical analysis methods to analyze images of gamma rays captured by NASA's Fermi Gamma-ray Space Telescope.
Researchers found that bacterial growth and biofilm formation depend on fluid flow and space shape. Fluid flow can interfere with quorum sensing, affecting disease-causing bacteria behavior.
Researchers at Princeton University create a method to selectively radiolabel compounds with tritium atoms, allowing for the study of drug metabolism and potential development speedup. The technique uses an iron-based catalyst that can tolerate various solvents, enabling the tracking of drug breakdown in the body.
Researchers found that if groups of targeted cells are large enough, the bacterial superweapon T6S can be thwarted. This allows protected interior cells to multiply quickly and replenish the group's numbers, making it impossible for the bacteria to take over. The study provides insight into how cells withstand powerful aggressors.
A new study reveals that tropical rainforests' predictable structure is driven by competition for sunlight, which fuels the growth of small trees in sunlit patches. This finding can improve climate simulations and estimate carbon storage in tropical forests.
Scientists recorded 3-D footage of neural activity in the nematode Caenorhabditis elegans, a worm species with a nervous system containing just 302 neurons. The study revealed surprising correlations between neural activity and behavior, including turning movements.
A team of researchers from Princeton University has discovered new genes that regulate memory and neuron repair in adult worms, which could have implications for human cognitive decline and traumatic brain injury. The study provides a more complete picture of how insulin/IGF-1 signaling pathway controls gene expression in neurons.
Researchers found that ringtailed lemurs reserve vocal exchanges for individuals with whom they have close relationships, using them to maintain social bonds even when separated. This study highlights the importance of vocal interactions in establishing familiarity and closeness, a concept applicable to human communication as well.
Researchers at Princeton University have developed a novel two-component catalyst system that performs the dehydrogenation reaction at room temperature. This method produces hydrogen gas and an alkene molecule without requiring high temperatures or precious metals, opening up new possibilities for chemical transformations.
A new study by Princeton University researchers suggests that warmer nights may lead to more carbon being released into the atmosphere, exacerbating climate change. The research found a strong correlation between tropical nighttime temperatures and variations in plant respiration rates, which produce carbon dioxide.
Researchers propose that plants 'decide' to thrive in certain environments, influencing biome productivity and composition. Nitrogen-fixing trees, which produce their own fertilizer, flourish in tropical zones but struggle in temperate forests, highlighting the importance of plant strategy in ecosystem evolution.