A Stanford study found that exercise restores youthful properties to muscle stem cells of old mice, improving their repair capabilities. The researchers identified a molecular pathway involved in this process and suggest that drugs targeting this pathway could be an effective substitute for exercise.
A new form of magnetic brain stimulation, SAINT, rapidly relieved symptoms of severe depression in 90% of participants. The treatment targets the brain's neurocircuitry and has shown promising results in treating people with treatment-resistant depression.
A Stanford study reports a new smart toilet that monitors for signs of disease using motion sensing, video analysis, and molecular testing. The device can detect various biomarkers, including those for colorectal or urologic cancers, and is designed to provide precise, individualized health feedback.
Researchers at Stanford University School of Medicine have successfully rejuvenated old human cells using stem cell technology, rewinding molecular hallmarks of aging and rendering treated cells nearly indistinguishable from their younger counterparts. The study found that exposure to specific proteins, known as Yamanaka factors, can i...
A Stanford study finds that young adults are unaware of the nicotine content in vaping products like Juul, raising concerns about their use and regulation. The study's findings also suggest that teens hide vaping products to avoid detection and choose them for stealth use and less noticeable smell.
A comprehensive analysis of 35 studies found AA to be nearly always more effective than psychotherapy in achieving abstinence and lowering health care costs. The fellowship's social interaction model provides emotional support and practical tips, facilitating behavior change.
A recent study of over 4,500 postmenopausal women diagnosed with breast cancer found that about 1 in 40 have BRCA1 or BRCA2 gene mutations. These mutations increase the risk of other cancers, including ovarian cancer, and may benefit from genetic testing.
Researchers found that women chairs of clinical departments earned an average of $70,000 to $80,000 less per year than their male counterparts. Despite controlling for factors such as productivity, specialization, and years on the job, the disparity remained.
A study by Stanford University School of Medicine investigators found that patients with ulcerative colitis have depleted levels of secondary bile acids and Ruminococcaceae bacteria in their intestines. These findings suggest that supplementing or restoring these missing metabolites may effectively treat intestinal inflammation.
Researchers at Stanford Medicine have developed a brain-wave signature that can predict which individuals with depression are most likely to respond to sertraline, an antidepressant. The study used electroencephalography and AI to identify the pattern in participants before treatment, allowing clinicians to make informed decisions abou...
Studies funded by the tanning industry are more likely to downplay risks and highlight perceived benefits of indoor tanning. Researchers analyzed 691 articles on indoor tanning and found that studies with financial ties to the industry were significantly more favorable, highlighting the need for independent scientific data.
Researchers have created a computer algorithm called CytoTRACE that can identify the most dangerous cancer cells by analyzing gene expression. The tool may help target cancer-causing genes and improve treatment outcomes for patients with aggressive forms of breast cancer.
Researchers identified four ageotypes: metabolic, immune, hepatic, and nephrotic, which determine biological pathways in the body. The study also found that lifestyle changes can slow aging rates in some individuals.
Researchers identified five practices: prepare with intention, listen intently and completely, agree on priorities, connect with the patient's story, and explore emotional cues. These practices aim to improve patient experiences and clinician satisfaction in medicine. The team is now evaluating their effectiveness in clinical settings.
Researchers at Stanford University School of Medicine found a common mutation in the ALDH2 enzyme may contribute to Alzheimer's disease, increasing cell damage from alcohol metabolism. The mutation, prevalent in East Asian populations, causes reduced enzyme activity and buildup of toxic acetaldehyde.
The US Feed the Future program has been found to reduce chronic malnutrition among children in sub-Saharan Africa, with a 3.9 percentage point decrease leading to 2.2 million fewer cases of stunting. The program's multifaceted approach to nutrition, combining agriculture and food security interventions, is credited with its success.
Researchers at Stanford University School of Medicine have identified a specific brain chemical, serotonin, responsible for the social behavior-enhancing effects of MDMA. The study suggests that novel treatments targeting this pathway may alleviate symptoms of psychiatric disorders marked by social awkwardness and withdrawal.
A Stanford-led study found that children with Type 1 diabetes exhibit abnormal brain-activity patterns during cognitive tasks, which worsen with age. The study's findings highlight the need for improved blood glucose control through treatment devices to mitigate potential learning and behavioral issues.
Researchers at Stanford University School of Medicine have developed a new approach to programming CAR-T cells that can prolong their activity and increase their effectiveness against human cancer cells. The technique uses ATAC-Seq to understand what happens when T cells become exhausted, and modifying CAR-T cells to restore balance in...
Researchers at Stanford University School of Medicine have developed a blood test that can reliably predict a person's age with 97% accuracy. By measuring the levels of 373 proteins in the blood, the test can identify three distinct inflection points in the human life cycle where physiological aging accelerates. This breakthrough could...
A study by Stanford University researchers found that omega-3 fatty acids influence stem cell division and fat cell formation. The findings suggest that consuming healthy fats can help regulate body weight and insulin sensitivity.
A new antibody treatment has shown promising results in a small pilot study, allowing participants with severe peanut allergies to eat a modest amount of peanut protein within 15 days. The treatment's effects lasted for up to 45 days, providing a potential breakthrough for food allergy treatments.
Researchers at Stanford and UC-San Francisco have developed an experimental drug that targets lung cancer by neutralizing a single protein, slowing its growth. The decoy version of the receptor protein was engineered to preferentially bind to the protein, repelling other proteins involved in tumor growth.
Researchers at Stanford University School of Medicine discovered that the cytoplasm of ruptured Xenopus frog eggs spontaneously reorganizes into cell-like compartments. These compartments divide like real cells, undergoing over 25 rounds of division, and retain the ability to undergo division.
A new study led by Stanford University and UCSF found that adolescents with atypical anorexia nervosa can have normal body weights yet be dangerously ill. The research showed that large, rapid weight loss is the best predictor of medical and psychological problems in these patients.
A Stanford University School of Medicine study found that even people with well-controlled epilepsy often experience cognitive deficits due to abnormal brain electrical activity called high-frequency oscillations. The research suggests that certain medications or implantable devices could be improved to alleviate these deficits.
A new study published in The Lancet Digital Health found that a digital clinical trial using the MyHeart Counts app increased physical activity by 10% in participants. The trial, which enrolled over 1,000 participants and ran for 18 months, showed that even simple prompts from a smartphone app can encourage people to exercise more.
Neighborhoods with high proportions of gay and bisexual men are more likely to have indoor tanning salons. The study suggests the tanning industry may be targeting vulnerable groups, increasing skin cancer risk.
A deadly neurological disease that affects infant boys has been linked to increased sensitivity to iron in the brain. A new study has identified a potential treatment, which enhances the survival of cells involved in the disorder.
Researchers at Stanford University identified 25 convergent amino acid changes in 18 genes involved in the development of the cochlear ganglion, a key component in echolocation. This discovery resolves a long-standing debate on whether echolocating bats and whales independently evolved similar genomic changes.
A study from Stanford University School of Medicine has found that a combination of light therapy and cognitive behavioral therapy can increase teen sleep duration by 43 minutes per night. The treatment consists of brief flashes of bright light to reset the body clocks, followed by motivation techniques to encourage earlier bedtimes.
Researchers at Stanford University School of Medicine discovered a molecular defect that could lead to an accurate, early diagnosis of Parkinson's disease. They also identified a compound that reverses this defect in cells from patients and prevents neuronal death in animal models.
A new Stanford University study has found that a four-week combination therapy involving brief light flashes and cognitive behavioral therapy can increase teenagers' sleep duration by 43 minutes per night. The treatment helped teens adjust their body clocks and motivated them to try earlier bedtimes.
Researchers at Stanford University School of Medicine discovered that severe brain cancers form synapses with healthy neurons, hijacking electrical signals to drive their own growth. The study found that interrupting these signals with an anti-epilepsy drug greatly reduced tumor growth in human tumors in mice.
The study found that temporarily disabling SETD3, a crucial protein needed for enteroviral replication, can protect against viral diseases. In mice bioengineered to lack SETD3, the viruses were unable to infect and replicate.
Researchers at Stanford University School of Medicine have found that inflammation in the lungs can wake up a silent genetic defect that causes sudden onset cases of pulmonary hypertension. The study suggests that limiting potential environmental causes of lung inflammation may help prevent the development of the disease.
Researchers at Stanford University School of Medicine found a way to improve neuron recovery in rats by blocking a molecule that controls genetic instructions. The approach, if applied to humans, may help patients with stroke, cardiac arrest, or major blood loss recover memory functions.
Researchers found tens of thousands of new protein families, likely involved in intercellular communication and warfare, among others. These small proteins may serve as new antibiotics or drugs for human use.
Researchers at Stanford University have developed a gel that reduces scar tissue and adhesions after cardiac surgery in animals, outperforming current methods. The gel, PNP 1:10, is safe and effective in preventing adhesions, with few side effects.
A new Stanford study found that stimulating a protective immune cell class, CD8 T cells, may reduce autoimmune disease severity. In a mouse model of multiple sclerosis, injecting mice with peptides recognized by these cells reduced disease severity and killed disease-causing immune cells.
Researchers at Stanford University found that Pivotal Response Treatment (PRT) is more effective than existing therapies at motivating children with autism to speak. The treatment involves parents setting up situations where their child is motivated to communicate, leading to improved communication skills and broader social abilities.
A phase-3 trial shows that combining rituximab with ibrutinib keeps patients disease-free for nearly three years and improves overall survival rates. The new treatment is more effective and better tolerated than traditional chemotherapy, revolutionizing the standard of care for chronic lymphocytic leukemia.
Researchers at Stanford University School of Medicine have discovered a new 'don't eat me' signal used by cancer cells to evade immune detection. Blocking this signal allows immune cells to attack and destroy cancer cells in mice implanted with human cancers, providing a potential basis for new anti-cancer therapies.
Researchers at Stanford University School of Medicine have pinpointed the RPS25 gene as a key player in the formation of amyotrophic lateral sclerosis (ALS) protein aggregates. Inhibiting this gene's function reduced toxic protein levels by 50 percent, suggesting a potential target for treating ALS and extending lifespan.
Researchers at Stanford University School of Medicine have discovered that specific cells in artery walls transform to form protective caps on plaque, reducing the risk of rupture. The new discovery sheds light on atherosclerosis progression and potential prevention strategies.
In a large 24-week study, rheumatoid arthritis patients saw substantial improvement from daily use of an experimental compound. Filgotinib, a selective JAK-1 inhibitor, showed significant benefits in reducing joint swelling and improving disease activity compared to placebo.
A new Stanford University School of Medicine study found that 79% of preschoolers with ADHD symptoms have impaired school readiness, compared to 13% of their peers. The research highlights the need for early identification and intervention strategies to support these children's educational success.
A Stanford University School of Medicine neuroscientist successfully stimulated nerve cells in mice visual cortex, inducing an illusory image and altering the animals' behavior. This breakthrough holds implications for understanding natural brain processing and psychiatric disorders.
Researchers at Stanford University School of Medicine identified a genetic mutation linked to dilated cardiomyopathy, a disease characterized by an enlarged heart's main pumping chamber. They found that treating patient-derived heart cells with existing drug inhibitors corrected the mutation's effects.
Scientists have discovered that zebrafish display two states of sleep similar to mammals, reptiles, and birds: slow-wave sleep and paradoxical sleep. This finding suggests that neural signatures of sleep evolved at least 450 million years ago in ancient fish.