Add BrightSurf on Google Email

Tohoku University


Research team creates more effective cancer therapy

Researchers at Tohoku University have developed a novel cancer therapy combining lymphatic drug delivery with total-body irradiation, showing superior antitumor effects in early stage lymph node metastasis. The treatment enhances systemic tumor immune responses and alters the tumor microenvironment.

SourceTohoku University·JournalCancer Science·DateSep 14, 2022

Bone transplant could resolve aging jaw defects

Researchers at Tohoku University have created a scaffold that supports the growth of new bone in large jaw defects in mice, bringing them closer to addressing the issue of aging jaw bone loss in humans. The technique uses a polylactic acid scaffold and has shown promise for treating large bone defects.

SourceTohoku University·JournalPNAS Nexus·DateAug 30, 2022

A brain mechanism underlying the evolution of anxiety

Researchers found that a specific amino acid substitution in the VMAT1 gene alters amygdala-dependent behaviors associated with anxiety, providing insight into its role in cognitive and emotional functions. Humanized substitutions of Vmat1 in mice revealed decreased levels of anxiety-like behaviors, supporting previous human studies.

SourceTohoku University·JournaliScience·DateAug 5, 2022

Training virtually can reduce psychosocial stress and anxiety

Researchers from Tohoku University found that virtual training can decrease psychosocial stress response and lower anxiety levels, comparable to real exercise. The study used immersive virtual reality to simulate physical activity, inducing physiological changes and cognitive benefits in young healthy subjects.

SourceTohoku University·JournalInternational Journal of Environmental Research and Public Health·DateJun 17, 2022

The material that could save industries heat

Scientists at Tohoku University have discovered a compound that can reversibly store and release large amounts of low-grade heat. The birnessite-type layered manganese dioxide with crystal water compound has shown better performance compared to other compounds for heat storage purposes.

SourceTohoku University·JournalNature Communications·DateApr 4, 2022

Gene regulation at its brightest

Researchers at Tohoku University create a novel method to quantify transcription factor activity in live organisms using viruses. This breakthrough enables scientists to understand how diseases develop and potentially treat them.

SourceTohoku University·JournaliScience·DateMar 18, 2022

Taking care of the young carers

A study by Tohoku University researchers found that adolescent carers in the UK reported higher psychological distress and lower mental well-being scores during the pandemic. The study highlights the urgent need for better psychosocial support for young carers, including psychoeducational sessions to build resilience.

SourceTohoku University·JournalJournal of Adolescent Health·DateMar 15, 2022

Maternal lead exposures correlated with sex ratios of offspring

A new study by Japanese researchers at Tohoku University Graduate School of Medicine found a correlation between maternal lead exposure and an increase in male births. The research suggests that even low levels of lead can affect the sex ratio of offspring, potentially contributing to Japan's declining proportion of male births.

SourceTohoku University·JournalScience of The Total Environment·DateMar 14, 2022

Genetic mechanisms of coral metamorphosis identified

Researchers have identified key molecular mechanisms driving coral metamorphosis, a radical transformation from free-swimming larvae to sedentary adult reef-builders. Alterations in gene expression and receptor signaling regulate the irreversibility of this process, enabling corals to adapt to their environment.

SourceTohoku University·JournalZoological Letters·DateMar 9, 2022

New lab model simulates effects of exercise on muscles

Researchers at Tohoku University developed a new lab-based system to grow human muscle cells that contract vigorously. They found that muscle cells from patients with sporadic inclusion body mitosis (sIBM) have similar muscular properties to healthy humans but exhibit altered responses to exercise.

SourceTohoku University·JournalScientific Reports·DateMar 2, 2022

Newly Identified Protein May Help Diagnose Ulcerative Colitis, Researchers Say

Researchers have discovered a potential new diagnostic marker for ulcerative colitis, identifying high levels of antibodies targeted at endothelial protein C receptors in patients with inflammatory bowel disease. The discovery could lead to the development of non-invasive blood tests to diagnose and track the progression of the disease.

SourceTohoku University·JournalClinical Gastroenterology and Hepatology·DateFeb 10, 2022