Researchers developed a 3D in vitro system to examine dynamic interactions between brain tumors and the surrounding extracellular matrix. The study found that fetal ECM supported tumor growth better than adult ECM, and lipid droplets released by glioblastoma cells may contribute to lower drug sensitivity.
Researchers at Tufts University developed transistors made from linen thread, enabling the creation of fully flexible devices with superior flexibility and material diversity. The device can be woven into fabric or worn on the skin, allowing for seamless integration with biological tissues.
An international team of researchers found that improving drinking water quality significantly reduces roundworm infections, with a 22% reduction when combined with sanitation and handwashing. The study suggests that sustainable approaches to disease control could be critical in tackling endemic infections.
A team of researchers from Tufts University has developed a 3D-printed pill that can sample bacteria in the gut without causing harm. The pill provides accurate identification of bacterial populations and their relative abundance, enabling better understanding of the role of different intestinal bacterial species in health and disease.
A novel lipid nanoparticle delivery system has been developed to deliver CRISPR/Cas9 gene editing tools into liver cells with up to 90% efficiency. This improvement has the potential to overcome technical hurdles for clinical applications, including treatment of hyperlipidemia and various diseases.
Researchers found that animals move faster through 'low quality' habitats, which could change conservation efforts. The study suggests using suburban and urban greenspace as strategic 'stepping stones' for species range shifts.
Researchers at Tufts University found that subsurface fluid injections can cause significant earthquake activity beyond the fluid diffusion zone. The study uses field experiment data and modeling of ground faults to support this hypothesis.
Researchers at Tufts University have created a computational model that explains how fragments of flatworms determine which end should form a tail and which should form a head. The model predicts the outcomes of genetic, pharmacological, and surgical manipulations, such as worms with two heads or two tails.
Engineers at Tufts University have created novel optical devices using 3D printed metamaterials with unique microwave or optical properties. The researchers developed a hybrid fabrication approach to create complex geometries and novel functionalities for wavelengths in the microwave range.
Researchers developed dyed threads that change color when detecting gases, providing a reusable and affordable safety asset in medical, workplace, military and rescue environments. The threads can detect gases as low as 50 parts per million and work under water.
A new study suggests that meeting a 2-degrees Celsius warming limit by 2100 is exceptionally difficult, but pursuing aggressive carbon-neutral energy production and rapid reductions can provide a hedge against high climate sensitivity scenarios. The researchers emphasize the need for immediate global action to mitigate climate change.
A study by Tufts University researchers found that African-American and Hispanic-dominant neighborhoods have installed significantly fewer rooftop solar photovoltaics than white-dominant neighborhoods, even after controlling for household income and home ownership. This disparity affects the deployment of solar energy across the US.
A new method for detecting bladder cancer has been developed using atomic force microscopy (AFM), which can accurately identify cancerous cells in urine samples with high sensitivity. The test demonstrates over 90% sensitivity in detecting bladder cancer, compared to 20-80% for current non-invasive diagnostics.
Researchers at Tufts University have discovered that delivering progesterone via a wearable bioreactor can induce partial limb regeneration in adult frogs. This breakthrough could lead to new treatments for amputation injuries, potentially benefiting millions of people worldwide.
Researchers at Tufts University have developed 3D human tissue culture models for the central nervous system that mimic brain structure and function. The models allow for the exploration of cell interactions, disease progression, and response to treatment, enabling the study of neurodegenerative diseases like Alzheimer's and Parkinson's.
Two new clinical trials are underway at Cummings Veterinary Medical Center at Tufts University to study deadly cancers in dogs. These studies focus on osteosarcoma and solid tumors, and may provide valuable information for human cancer treatments.
Scientists at Tufts University have found that amputation of one limb immediately reflects in the bioelectric properties of the opposing, un-damaged limb in developing frogs. The phenomenon, dubbed 'bioelectric injury mirroring,' indicates that information about damage to tissues is available within 30 seconds.
Researchers at Tufts University have developed magnetic elastomeric composites that can flex, grip, release or rotate when exposed to lasers or sunlight. The materials can exhibit complex movements like crawling, walking or swimming and can be triggered and controlled wirelessly using light.
Researchers at Tufts University have developed smart bandages with integrated pH and temperature sensors that can detect infection and inflammation. These bandages can deliver targeted drug treatments to improve the chances of healing for chronic wounds, which are a significant medical problem affecting millions of people worldwide.
Researchers found that honey bees shift their nutrient intake according to the season, increasing calcium consumption in the fall and seeking high-potassium sources. This adaptation helps prepare the bees for colder months when they need these minerals to generate warmth.
A new algorithm developed by Tufts University researchers enables the self-localization of IoT devices on 5G networks, eliminating the need for centralized anchors and improving location-based services. This scalable solution can meet the demands of a projected 50 billion connected products by 2020.
Researchers identified two tryptophan metabolites produced by gut bacteria that modulate inflammation, potentially reducing the severity of non-alcoholic fatty liver disease. The study found that these metabolites reduce cytokine levels and macrophage activity, which are key contributors to inflammation.
A study of 2.3 million LinkedIn users found that revealing the number of applicants increases applications from diverse backgrounds, including women and inexperienced workers. This could help companies close diversity gaps and bolster labor markets.
Researchers at Tufts University created a genetically modified yeast that can efficiently consume xylose, enabling faster growth and higher cell densities. The new synthetic regulon, dubbed XYL, preserved a natural interaction between feeding and survival genes, leading to improved survival of the xylose-eating yeast organism.
Researchers at Tufts University developed miniaturized sensors that can detect nutrients, chemicals and physiological states, offering a non-invasive way to monitor dietary intake. The sensors, with a footprint of 2mm x 2mm, transmit data wirelessly in response to radiofrequency signals.
Tufts University biologists computationally model and manipulate electrical patterns in developing frog embryos to prevent nicotine-induced defects. They identify a hyperpolarization-activated channel that restores normal bioelectric patterns, rescuing embryos from brain defects.
The study developed an optical tool that can read metabolism at subcellular resolution without perturbing cells or destroying them. The method identifies specific metabolic signatures associated with diabetes, cancer, cardiovascular, and neurodegenerative diseases.
Researchers at Tufts University have developed highly selective membrane filters that can separate organic compounds by size and electrostatic charge, potentially reducing energy consumption and carbon emissions. The membranes mimic biological systems and can sort compounds in various filtration systems.
Researchers at Tufts University have developed a new approach to analyzing complex genomic rearrangements (CGRs), enabling rapid and precise identification of their causes and impact on DNA and cellular formation. This breakthrough could lead to significant advances in diagnosing and treating genetic disorders and certain cancers.
Researchers at Tufts University have discovered a new method for directly converting methane into methanol using a heterogeneous catalyst and low-cost molecular oxygen. This breakthrough could lead to more efficient and cost-effective production of chemicals, fuels, and high-grade hydrogen.
Xiaocheng Jiang will use the $450,000 grant to develop innovative method of observing fundamental cellular and molecular processes using atomic-resolution electron microscopic methods. The platform could enable new insights about biologically significant processes such as bioelectrical signaling and cancer metastasis.
Researchers at Tufts University will develop devices to improve the collection, storage and transport of blood samples in field settings, enhancing sample reliability for disease surveillance and diagnostics.
A team of Tufts University scientists recommends international Arctic collaboration to address geopolitical tensions between the US and Russia. The proposed agreement aims to promote sustainability, scientific research, and education across borders in the Arctic region.
Researchers removed frog embryos' brains and found muscles & nerves developed abnormally without brain; they successfully rescued defects with human-approved drugs. The study reveals the brain's role in early development and could lead to better ways to address birth defects.
Tufts University will establish the Institute for Research on Learning and Instruction (IRLI) with a focus on understanding how students learn at the collegiate level. The institute aims to develop evidence-based educational methods to give students the skills and knowledge they need for the future.
Researchers project a significant increase in harmful algal blooms in US freshwater reservoirs and lakes due to climate change. The study predicts that the biggest impact will be felt by recreation areas in the Southeast, with more rural regions also affected.
A study by Tufts University researchers found significant changes in miRNA expression levels in dogs with myxomatous mitral valve disease (MMVD) and congestive heart failure. The study identified new genomic biomarkers, including exosomal miR-181c and miR-495, which could provide insight into diagnosis and therapies for MMVD and human ...
A nationwide survey of hospitals, eldercare facilities, and therapy animal organizations reveals gaps in health and safety policies for therapy animal visits. Many facilities lack proper guidelines for animal health, behavior, and hygiene, posing risks to both humans and animals.
Researchers studying space-traveling flatworms found that microgravity affects their regeneration, behavior and microbiome. The worms' bodies underwent permanent changes after exposure to space, including spontaneous fission and altered biological states.
The Listening Project initiative aims to increase instructors' awareness of implicit bias and support efforts to elicit scientific thought in all students. The program, led by Roger Tobin and David Hammer, seeks to broaden participation and cultivate talents among undergraduate students from diverse backgrounds.
Second-grade students who read aloud to dogs showed improved attitudes about reading, with significant increases in academic reading attitudes. Reading skills remained stable in both groups.
Researchers found that administering certain drugs to make cells more negatively charged strengthens tadpoles' innate immune response to E. coli infection. Removing tail buds also increases survival rate.
The study reveals that bioelectric patterns can override the default body shape called for by a genome, allowing researchers to edit the target morphology of an animal with a wild-type genomic sequence. This work provides clues about why certain individuals have different biological outcomes when exposed to the same treatment as others.
Research by Tufts University chemist Mary Jane Shultz sheds new light on snowflake formation. The study reveals that flat sides of a snowflake consist of a bilayer structure, contradicting previous theories.
Research by Tufts University shows that paper wasps facilitate grape sour rot disease, causing millions of dollars in losses. The study found that wasps carry polymicrobial communities and disperse live microorganisms, increasing disease incidence.
Tufts University faculty members have won prestigious NSF CAREER Awards for their research in physics, biomedical engineering, civil engineering, and mechanical engineering. The winners will use their awards to advance knowledge and education in their fields.
Researchers at Tufts University successfully treated blind tadpoles with a serotonin receptor drug to induce nerve growth and promote visual learning, enabling the animals to process visual information from their grafted eyes. The study provides a potential road map for promoting innervation in regenerative medicine.
Researchers developed a method to transform silk protein into complex materials that can be easily programmed at the nano-, micro-, and macro-scales. The resulting materials are ultralight, robust, and feature a web-like structure with aerated pores.
A new study from Tufts University reveals that honey bees fine-tune their nutrient-seeking behavior based on the seasonality of their floral diet. Bees forage for minerals like calcium, magnesium, and potassium in water sources that reflect what's lacking in their pollen-based diet.
Researchers used AI to predict a trio of reagents that generated a never-before-seen cancer-like phenotype in tadpoles, demonstrating its potential in controlling complex biological systems. The study showcases how AI can help human researchers achieve new outcomes in fields like oncology and regenerative medicine.