A study published by UC San Diego researchers found that heat waves significantly increase emergency room visits among people experiencing homelessness. The study highlights the need for heat action plans to protect vulnerable populations from extreme weather conditions.
Researchers found that Botox-treated patients reported anxiety significantly less often than those undergoing different treatments for similar conditions. The data used was from the FDA's Adverse Effect Reporting System and showed a 22-72% lower risk of anxiety for four out of eight conditions and injection sites.
The Nixon Visions Foundation has given a significant gift to support studies of the PRPH2 gene linked to macular dystrophy and boost stem cell research aimed at developing early diagnosis and a cure for this devastating genetic eye disease. Researchers hope to make a tremendous impact on people with this inherited eye disease.
Researchers at University of California San Diego found a way to boost innate immunity in liver cancer, making tumors highly responsive to immunotherapy. The combination of anti-PD-L1 antibody and polyIC molecule showed remarkable synergistic effects in liver tumor inhibition.
Researchers at UC San Diego School of Medicine developed a shortened 7-item version of the SD-WISE-28 to assess wisdom. The Jeste-Thomas Wisdom Index has high validity and positive correlations with resilience, happiness, and mental well-being.
Scientists at UC San Diego create nanoparticles that mimic the flu virus's ability to escape endosomes, enabling efficient delivery of mRNA into cells. This breakthrough could lead to improved delivery of mRNA vaccines and therapies.
Scientists have detected a significant acceleration of the Antarctic Circumpolar Current (ACC), the only ocean current that circumnavigates the planet. The study found that climate change is causing the ACC to speed up, with prevailing westerly winds energizing ocean eddies and facilitating property exchange between ocean basins.
Researchers found that high avocado consumption led to reduced caloric energy intake, lower dairy and meat consumption, and improved fiber and nutrient intake. However, unexpected decreases in calcium and certain minerals were also observed.
Researchers have developed a new AI technique, MuSIC, which combines microscopy, biochemistry techniques and artificial intelligence to reveal approximately 70 components contained within a human kidney cell line, half of which had never been seen before.
Researchers discovered the retrosplenial cortex as the site of value decision-making in the brain. Persistency allows value signals to be effectively represented across different brain areas, especially the RSC. Artificial intelligence networks mimicking mouse decisions showed remarkably similar results.
Researchers found that wet masks make it more difficult for respiratory droplets to penetrate and escape the mask, splintering into smaller aerosolized particles. This is because wet masks create additional resistance due to their hydrophobic or hydrophilic materials, making them more effective at stopping droplet penetration.
UC San Diego researchers developed a computer model to understand how viruses travel through the air, shedding new light on airborne COVID-19 transmission. The model simulates aerosol behavior and helps explain why SARS-CoV-2 is highly transmissible through the air.
A single-cell chromatin atlas for the human genome reveals how genes are turned on or off in different cells, a major step toward understanding the connections between genetics and disease. The findings identify disease-trait-relevant cell types for 240 multi-genic traits and diseases.
A multi-center study assesses medicinal mushrooms and Chinese herbs for therapeutic benefit in treating acute COVID-19 infection. The MACH-19 trial evaluates the safety and feasibility of two investigational compounds, one in capsule form and another as a Chinese herbal formula.
A new study published in Science Advances has shed light on the genetic basis of human appearance features by investigating the role of Hox genes. The researchers replaced the proboscipedia gene in a common laboratory fruit fly with its counterpart from a rarer Hawaiian cousin, revealing that Hox genes function as scaffolds for downstr...
New study suggests inhibiting Shp2 in tumor cells may boost tumor growth and survival, complicating its use as a potential cancer therapy for HCC.
Research suggests that larger bee colonies with comfortable food stores are less willing to take risks, while smaller colonies with limited resources are more likely to ignore warning signals. This study provides insights into the complex communication system of bees and its implications for understanding biological collectives.
A new study projects that more than eight million tons of pandemic-associated plastic waste have been generated globally, with over 25,000 tons entering the global ocean. The research highlights the need for improved medical waste management in developing countries and calls for global action to reduce plastic pollution.
Researchers at UC San Diego have created a CRISPR-based rapid diagnostic technology that detects SARS-CoV-2, the coronavirus causing COVID-19. The new SENSR system is designed to simplify SARS-CoV-2 detection with a goal of eventual adaptation for in-home use.
Researchers at University of California San Diego School of Medicine identified the anterior insula's role in predicting and emotionally processing pain in HIV-DSP patients. The study suggests that reduced anterior insula activity or increased cingulate activity may improve pain outcomes for these patients.
A team of psychological scientists and criminologists recommend testing eyewitness memory only once to prevent contaminated memories from convicting innocent people. The first identification is the most reliable test, which can avoid further contamination and ensure justice.
Researchers have made significant progress in generating neurons in the lab, a potential therapeutic option for replacing lost neurons in neurodegenerative conditions like Parkinson's disease. A $9 million grant will support further research and development of this novel treatment approach.
A recent study by the University of California - San Diego team discovered that glycogen regulates and promotes fat metabolism, helping to balance energy intake and expenditure. The research suggests modulating glycogen metabolism in fat cells could provide new approaches for weight loss and improved metabolic health.
Researchers have discovered a more effective treatment for children with Kawasaki disease and multisystem inflammatory syndrome in children (MIS-C), a rare COVID-19 reaction. The new therapy, infliximab, reduces fever duration, hospitalizations, and anemia compared to standard IVIG treatment.
Researchers describe how cancer cells exploit genetic and cellular processes to promote tumor survival and growth. The study found that aneuploidy, a condition of abnormal chromosome number, intersects with the stress response mechanism in cancer cells, leading to immune cell dysregulation.
A national network has been launched to promote understanding of planetary limits, envision scenarios for humanity to thrive within limits, and advise governments on developing effective responses. The essay warns that current economic growth, energy use, and resource consumption will overshoot Earth's finite limits if not addressed.
Researchers investigated whether continued magnetic seizure therapy (MST) could effectively prevent the relapse of treatment-resistant depression. The study found that MST was associated with a lower relapse rate compared to earlier research assessing one-time, acute MST.
A recent UC San Diego study has found that e-cigarette use does not help smokers stay off cigarettes, but rather increases the risk of relapse. Former smokers who switched to e-cigarettes were more likely to relapse compared to those who remained tobacco-free.
A genomic study revealed causative gene variants for inherited retinal dystrophies (IRDs) in diverse populations, with significant findings for Mexican, Pakistani, and European American participants. The study identified new gene variants and mutations contributing to IRDs, shedding light on disease variation and presentation.
Researchers identified a bacterium on healthy cats that produces antibiotics against severe skin infections in humans and pets. The discovery may lead to new treatments for MRSP infections in dogs and potentially other inflammatory skin diseases.
The study found that a stack pressure of 350 kilo Pascal increases lithium particle deposition in neat columns, improving stability and reducing the risk of short circuits. Additionally, partial discharge during cycling can also boost performance without affecting the solid electrolyte interphase structure.
Researchers at UC San Diego will document brain development from birth through early childhood, focusing on environmental factors and mental disorders. The HBCD study aims to optimize brain imaging technologies and predict future behavioral problems.
Researchers conducted genomic evaluations of advanced malignancies to develop matched, individualized combination therapies. The study found that precision cancer therapy improved median overall survival rate by 3.9 months compared to standard care.
A new research center will use genomic data and socioeconomic factors to better predict health outcomes in individuals of diverse ancestry. The center aims to develop computational tools to combine large datasets and analyze them for consistent relationships among admixed populations.
Researchers found that lower performing students reported higher stress levels due to multiple factors, including work obligations, feeling like they don't belong, or lack of confidence. The study suggests that successful interventions should target multiple areas of student stress.
Researchers at UC San Diego School of Medicine report that children with multisystem inflammatory syndrome in children (MIS-C) have normal T cell responses to the COVID-19 virus, contrary to previous hypotheses. This suggests that MIS-C may not be caused by an abnormal immune response to the virus.
Scientists at the University of California San Diego have discovered that planar cell polarity is a widely used mechanism for forming and maintaining glutamatergic synapses. The study found that Prickle protein plays a crucial role in stabilizing these synapses, which are essential for neuronal communication.
Researchers create detailed atlas of mouse cerebrum, revealing distinct cell types and gene regulatory elements. The study provides insights into brain organization and function, with potential implications for human neurological diseases and traits.
Researchers developed a real-time measurement technique to detect algae health issues, detecting threats 37-76 hours earlier than traditional methods. This could save hundreds of millions of dollars in algae biomass losses and protect the world's most promising sustainable product source.
Researchers discovered an ancient mangrove ecosystem in the Yucatan Peninsula, revealing how coastal mangroves adapted to a warmer world with higher sea levels. The study provides insights into past climate change impacts and its relevance to future scenarios of relative sea-level rise.
Scientists identified a rare genetic condition affecting prenatal development, leading to lifelong disabilities in children. They discovered a potential method to prevent the condition by administering a drug during pregnancy, which boosted Wnt signaling and restored normal growth in mouse embryos.
Researchers found that methamphetamine, cocaine, and nicotine withdrawal share similar features in mouse brains, including reduced modularity and increased functional connectivity. This reorganization may contribute to the addictive nature of psychostimulants.
By reading electrical signals in a bird's brain, researchers can predict specific syllables and when they will be sung. This breakthrough technology has the potential to develop vocal prostheses for humans with speech disorders.
Researchers at University of California San Diego created a high-performance all-solid-state battery using pure-silicon anode, showing safe, long-lasting, and energy-dense properties. The new battery technology offers a promising path forward for silicon anodes, which were previously limited by liquid electrolytes.
Researchers developed a soft robotic steerable micro-catheter for precise brain surgery, enabling targeted treatment of cerebral disorders. The innovative catheter uses biomimicry to navigate and maneuver within the brain's complex anatomy.
Researchers at UC San Diego developed a new UWB system that enables precise 3D localization and tracking for applications like VR, sports analytics, and autonomous robots. The system uses low power and achieves latency of just one millisecond.
Researchers developed a treatment using cowpea mosaic virus nanoparticles that target lung tumors, slowing tumor growth and preventing cancer spread. The treatment showed efficacy against aggressive cancer cell lines and may offer protection to patients at high risk of metastatic disease.
Researchers at UC San Diego are developing higher-resolution sensor grids with increased density to improve diagnosis and treatment of drug-resistant epilepsy. The team plans to test these grids in pigs before conducting clinical trials, aiming to provide surgeons with a clearer picture of brain regions triggering seizures.
Researchers at UC San Diego School of Medicine are studying the impact of antibiotics on breast milk and infant health. The team will investigate how antibiotics alter the composition of breast milk and impact the infant microbiome, metabolome and immune response.
Researchers at UC San Diego develop precision-guided sterile insect technique (pgSIT) to control mosquito populations. The system uses CRISPR to alter genes linked to male fertility and female flight in Aedes aegypti, reducing disease transmission.