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University of Chicago


New biosensor solves old quantum riddle

Researchers create new quantum biosensor using diamond nanoparticles and specially engineered shell, outperforming previous attempts. The breakthrough sheds light on a longstanding mystery in quantum materials and shows up to fourfold improvements in spin coherence.

SourceUniversity of Chicago·JournalProceedings of the National Academy of Sciences·DateMay 22, 2025

AI is good at weather forecasting. Can it predict freak weather events?

A new study by UChicago scientists found that AI-powered weather prediction models are remarkable but not magical, struggling to predict unprecedented weather events. The model can achieve impressive accuracy for short-term forecasts but fails to extrapolate beyond existing training data, leading to false negatives and potential mispre...

SourceUniversity of Chicago·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateMay 22, 2025

Computational tool predicts materials for new energy economy

Researchers at UChicago's Catalyst Design for Decarbonization Center developed a new computational tool that predicts stable metal-organic frameworks (MOFs) for efficient energy storage and catalysis. The tool uses thermodynamic integration to calculate MOF stability, enabling the rapid discovery of promising materials.

SourceUniversity of Chicago·JournalJournal of the American Chemical Society·DateMay 21, 2025

Scientists discover one of the world’s thinnest semiconductor junctions forming inside a quantum material

Researchers at University of Chicago Pritzker School of Molecular Engineering discovered one of the world's thinnest semiconductor junctions within a quantum material. The discovery could lead to ultra-miniaturized electronic components and provides insight into electron behavior in materials designed for quantum applications.

SourceUniversity of Chicago·JournalNanoscale·DateMay 20, 2025

Food as medicine: How diet shapes gut microbiome health

Researchers found that mice on a Mediterranean-style diet recovered quickly and restored a healthy gut microbiome after antibiotics, while those on a Western-style diet were susceptible to infection. The study suggests that diet can be used to treat infections in patients following cancer treatment or organ transplants.

SourceUniversity of Chicago·JournalNature·TypeExperimental study·DateMay 6, 2025

A Big Data approach for battery electrolytes

A new paper outlines a path for AI and machine learning to help build tomorrow’s batteries by maximizing three components: ionic conductivity, oxidative stability, and Coulombic efficiency. The team used a dataset compiled from 250 research papers to identify promising candidates for scientists to test in the lab.

SourceUniversity of Chicago·JournalChemistry of Materials·DateMay 5, 2025

New rules for the game of memory

A new study from the University of Chicago suggests that patterns of activity in the brain continually reshape memories, even after learning has occurred. Researchers found that behavioral timescale synaptic plasticity (BTSP) is a key driver of this process, explaining the dynamic shifting of place cells in the hippocampus.

SourceUniversity of Chicago·JournalNature Neuroscience·TypeExperimental study·DateMar 20, 2025

How big brains and flexible skulls led to the evolution of modern birds

Research from the University of Chicago and University of Missouri reveals how modern birds' larger brains led to changes in their skulls, jaw muscles, and feeding mechanics. This evolution allowed for the development of cranial kinesis, enabling birds to move different parts of their skull independently.

SourceUniversity of Chicago·JournalProceedings of the National Academy of Sciences·TypeImaging analysis·DateMar 17, 2025

Terabytes of data in a millimeter crystal

The UChicago Pritzker Molecular Engineering team has developed a technique to store classical computer memory in crystal gaps where atoms should be, enabling terabytes of data storage in a small millimeter-sized cube. This innovation combines quantum techniques with solid-state physics to revolutionize classical non-quantum computers.

SourceUniversity of Chicago·JournalNanophotonics·DateFeb 14, 2025

A symphony in quantum

Researchers from UChicago Pritzker Molecular Engineering have demonstrated high-fidelity entanglement between two acoustic wave resonators, a significant breakthrough in the science of quantum sound. The team showed that they can entangle massive objects using collective motion of nanoscale mechanical vibrations.

SourceUniversity of Chicago·JournalNature Communications·DateFeb 10, 2025

Better texture for better batteries

Researchers at University of Chicago improved battery performance by studying metal texture, discovering that adding a thin layer of silicon enhances desired properties. The new technology has the potential to increase power densities and enable more efficient energy storage.

SourceUniversity of Chicago·JournalJoule·DateFeb 10, 2025

Rethinking the quantum chip

Researchers at UChicago Pritzker School of Molecular Engineering have designed a new architecture for scaling up superconducting quantum devices. The modular design allows for flexible operability and enables the connection of any two qubits within a few nanoseconds, promoting high-fidelity quantum gates and entanglement.

SourceUniversity of Chicago·JournalPhysical Review X·DateDec 10, 2024

Global partnership channels more than USD 1 billion to scale up weather services for hundreds of millions of farmers across Asia, Latin America and Africa

A global partnership has committed over $1 billion to scale up weather services for hundreds of millions of farmers across Asia, Latin America, and Africa. The initiative aims to provide high-quality, farmer-centered forecasts using AI-supported weather forecasting to build resilience and support adaptation to climate change.

Innovative bioelectronic device offers new hope in the fight against bacterial infections

Researchers at the University of Chicago and UC San Diego have developed a cutting-edge bioelectronic device that harnesses the natural electrical activity of certain bacteria to manage infections. The device achieves remarkable results by delivering gentle electrical signals, reducing bacterial colonization nearly tenfold.

SourceUniversity of Chicago·JournalDevice·TypeExperimental study·DateOct 24, 2024

Beyond ‘one pore at a time’

Researchers at University of Chicago developed a novel method to create high-density pores in membranes with intentional weak spots, enabling precise control over pore size and concentration. This technique has potential applications in water treatment, fuel cells, and other fields.

SourceUniversity of Chicago·JournalNature Communications·DateOct 2, 2024

UChicago scientists decode key mutation in many cancers

A study from UChicago scientists reveals a significant role of RNA in DNA packaging and storage through the gene TET2. This pathway explains why many cancers involve TET2-related mutations and offers new targets for treatments. The discovery also sheds light on the connection between TET2 mutations and increased risks of heart disease,...

SourceUniversity of Chicago·JournalNature·DateOct 2, 2024

Activity in brain system that controls eye movements highlights importance of spatial thinking

The superior colliculus, a brain region traditionally thought to control eye movements, also plays a crucial role in complex cognitive tasks like visual categorization and decision making. Research from UChicago shows that activity in this region is more involved than previously thought in guiding cognitive processes.

SourceUniversity of Chicago·JournalNature Neuroscience·TypeExperimental study·DateSep 19, 2024

How cells control gene expression by cleaning up their mistakes

Cells produce three times as many 'unproductive' transcripts with mistakes or unexpected configurations as they do steady-state, finished RNA. These unproductive transcripts are quickly destroyed by a cellular process called nonsense-mediated decay (NMD), which suggests the cell intentionally makes mistakes to regulate gene expression....

SourceUniversity of Chicago·JournalNature Genetics·TypeData/statistical analysis·DateSep 2, 2024