A University of Ottawa study found that almost two-thirds of Canadians with stroke experience disturbed sleep, and those affected are up to 7 times more likely to report multiple sleep problems. The study highlights the need for better awareness and guidance on managing sleep disorders in stroke patients.
Dr. Natasha Kekre, a University of Ottawa associate professor and hematologist, has secured millions in funding and published numerous peer-reviewed papers on CAR-T cellular therapies for cancer treatment. Her work has advanced the immunotherapy field in Canada and made her an expert in cancer immunotherapies.
A new method for measuring bifacial solar panel performance has been developed by the University of Ottawa SUNLAB team. The study proposes a characterization method that considers external effects of ground cover like snow, grass, and soil, providing a way to accurately test panel performance indoors.
Researchers discovered host proteins APOBEC3 can aid HIV's latency, a major hurdle to cure research. The finding raises questions about the role of these proteins and potential ways to block their activity to inhibit viral persistence.
Research from the University of Ottawa finds that oral contraceptives' effects on brain and mood in women may be linked to age of onset and gut microbiome. The study suggests adolescence as a critical period for understanding OCs' impact, as it influences brain development and hormonal changes.
A University of Ottawa-led team identified a new entry route for SARS-CoV-2 using metalloproteinases, which may lead to more widespread cell infection and severe illness. The study suggests that variants like the Delta strain may prefer this entry method, while others like Omicron do not.
Researchers at the University of Ottawa have developed a new technique to differentiate the mirror images of a chiral molecule, a problem that was believed to be unsolvable for nearly 20 years. The team used linear polarized helical light beams to enhance sensitivity and observed differential absorption in achiral molecules.
Professor Jan Grabowski's research on the Holocaust reveals untold stories of average citizens' roles in persecution. His work shows that rural counties contributed to terror, and non-Jews took initiative against Jewish communities.
Researchers have detected five emerging tick-borne pathogens in Central Canada, including those causing Lyme disease and babesiosis. Climate change and habitat fragmentation contribute to the spread of these pathogens, highlighting the need for increased awareness and protection measures.
Researchers at the University of Ottawa have discovered that patients with electrolyte abnormalities are twice as likely to be diagnosed with an eating disorder. This study analyzed Ontario health data between 2008 and 2020, identifying a potential preventative treatment for approximately 1 million Canadians.
Researchers from the University of Ottawa found an association between marijuana smoking and chronic damage to airways, including higher rates of paraseptal emphysema and airway inflammatory changes. The study suggests that marijuana smoking may lead to additional lung damage beyond what is seen in tobacco smokers.
The DocMapper.ca platform provides an interactive map listing physicians' names, contact info, and language skills in the Ottawa and Renfrew County area. Available in English and French, it lists over 50 languages, addressing a significant language barrier for patients seeking family care.
A new study from the University of Ottawa reveals that morning types tend to have superior verbal ability, contrary to previous research suggesting that evening types have an advantage. The study found that accounting for factors like bedtime and age, morning individuals outperformed their evening counterparts in verbal intelligence.
A novel genetic analysis by University of Ottawa researchers reveals that climate change could lead to an increased risk of viral spillover in the High Arctic. This increased risk may result in new viruses infecting previously uninfected hosts, potentially leading to emerging pandemics.
A new type of satellite imagery with a spatial resolution of 15 cm has been used to detect and monitor critically endangered North Atlantic right whales. The technology allows for the identification of individual whales and their habitats, which will have significant implications for conservation efforts.
Researchers found that the return of radiolarians, a tiny marine organism, helped restore habitable conditions after the massive extinction event. The study suggests that every microorganism plays a vital role in regulating biogeochemical cycles and conservation of the planet.
A new paper published in Social Science & Medicine proposes that synthetic steroids were administered to female captives in Nazi concentration camps to prevent menstruation and fertility. The study, led by Dr. Peggy J. Kleinplatz, is based on historical evidence and testimony from Holocaust survivors, who reported suspicious food ratio...
A University of Ottawa research team has made new discoveries on how motor skills are learned and stored in the brain. By studying mice, they found that a specific transcription factor called NPAS4 regulates gene changes in inhibitory neurons, leading to the formation of learning-associated neuron ensembles.
The University of Ottawa-led team aims to bridge the gap between heart and brain health by developing new diagnostic tools and treatments. They will focus on improving patient outcomes for disorders linked to both organs.
A study published in Cell Stem Cell found that mitochondrial dynamics regulate the dormant state of adult muscle stem cells, which are essential for tissue stability. The researchers discovered that the protein OPA1 regulates this process and its depletion leads to severe muscle stem cell defects.
A meta-analysis of 64 longitudinal studies found that mental health problems remained elevated globally during the pandemic, with North Americans suffering from increased anxiety and depression. In contrast, Latin America and Europe experienced higher rates of insomnia.
A population-based retrospective cohort study found that COVID-19 vaccination during pregnancy is not associated with an increased risk of preterm birth, small for gestational age at birth, or stillbirth. The study concluded that COVID-19 vaccination during pregnancy can inform evidence-based decision-making about its safety.
New research from the University of Ottawa finds that climate change is waking bumblebees earlier from winter hibernation, putting the species at risk. The study found that this early emergence timing puts bees out of sync with their food sources, leading to smaller colonies and lower survival rates.
A new study suggests that exercise training is crucial for individuals with diet-resistant obesity, improving skeletal muscle metabolism and enhancing weight loss capacity. The research challenges the one-size-fits-all approach to treating obesity and has the potential to help reshape the science of weight-loss programs.
Researchers found lower stages of breast cancer in women aged 40-49 compared to those aged 50-59, with a significant decrease in stage 4 cases. This suggests that early detection through regular mammograms can lead to better health outcomes and survival rates.
Researchers discovered that vitamin K acts as an antioxidant, inhibiting ferroptotic cell death and identifying FSP1 as the warfarin-insensitive enzyme responsible. This finding has implications for treating Alzheimer's disease and acute organ injuries.
CoVaRR-Net is investing $6.9 million in 15 research projects focused on understanding Omicron subvariants and finding solutions to curb their spread. The studies will explore various aspects of variants, including viral transmission between animals and people, new variant mutations, and the impact of social factors on Indigenous Peoples.
A University of Ottawa-led team has developed an AI-based deep learning model to identify cystic hygroma, a rare and life-threatening disorder, from first-trimester ultrasound scans with high sensitivity and specificity. The approach may be applied to other fetal anomalies identified by ultrasonography.
A new study published in JAMA Internal Medicine suggests that COVID-19 vaccination during pregnancy can provide protection to newborns against SARS-CoV-2 infection. The study found a lower incidence of confirmed SARS-CoV-2 infection in infants born to vaccinated mothers compared to unvaccinated mothers.
Case volumes grew by 180% as the eConsult service launched a sub-specialty COVID-19 group in March 2020. The service provided real-time data advice from infectious disease specialists on novel coronavirus, reducing unnecessary specialty referrals and saving time and money.
Researchers suggest a novel neuroimaging technique can unveil Alzheimer's disease secrets and predict symptom risk. The 'neuromelanin-sensitive MRI' method provides insights into the brain's noradrenergic system, linked to aggressive behavior and cognitive decline.
A recent study found that COVID-19 spreads extensively in households, with approximately 50% of household members infected from the first-infected individual. Children were less likely to spread the virus but equally likely to become infected as adults, highlighting their potential role in transmission.
Researchers developed a virus that infects cancer cells, killing them while sending signals to nearby uninfected cells for viral attack. This approach shrinks tumors and enhances cancer-killing efficacy in various models, including pancreatic and ovarian cancers.
The Sedentary Behaviour Research Network has released international guidelines to minimize health impacts of sedentary behaviour in schools. The recommendations aim to counteract excessive screen time and promote healthy movement behaviours among students.
A novel class of bed net that kills mosquitoes resistant to traditional insecticides by making them unable to move or fly significantly reduces malaria infection in children. The study found a 43% reduction in malaria prevalence and 44% reduction in clinical episodes over two years.
Researchers analyzed nearly 100,000 pregnancies and found no association between COVID-19 vaccination and poor birth outcomes. The study provides further evidence on the safety of mRNA vaccines for pregnant individuals.
Researchers develop novel therapeutic approach for treating tuberculosis using phosphatase inhibitors, offering potential benefits for TB research and basic biology exploration. The discovery provides a promising alternative to traditional antibiotic-based treatments and has significant implications for combating antimicrobial resistance.
University of Ottawa scientists, collaborating with Yale researchers, have discovered the hidden influence of a single variation between histone H3.1 and H3.3 proteins. This finding could expand our understanding of DNA damage repair and its role in diseases like cancers and sponastrine dysplasia.
Researchers at the University of Ottawa developed a spray-on technology using customized nanogold and peptides that can restore heart function and electrical conductivity in damaged hearts. The therapy showed promising results in lab mice, with no off-target organ infiltration by tiny gold particles.
A University of Ottawa group is conducting research to equip healthcare professionals with resources to aid patients in French-speaking minority settings make informed decisions about COVID-19 vaccines. The project aims to address language barriers and combat patient disinformation.
Researchers have solved atomic-level structures of the muscle-type nicotinic acetylcholine receptor, a crucial step in understanding its function. The new findings could lead to breakthroughs in treating neurological disorders such as congenital myasthenic syndrome and myasthenia gravis.
A University of Ottawa review provides the first field-wide summary of how pesticide exposure affects social bee gut microbiotas. The study found that pesticides disturb microbial communities, leading to a loss of benefits and potential decline in bee health and performance.
Researchers found that glaciers in the Northern Hemisphere lost a total area of 390 km² per year, with 60% attributed to the Greenland Ice Sheet. Only 3% of glaciers advanced during this period. The study highlights the impact of climate change on marine-terminating glaciers.
A study found frequent rates of respiratory infections and wheezing in young First Nations children due to poor housing conditions, including inadequate ventilation, mold, and wood smoke contaminants. The researchers urge action on improving housing and infrastructure in communities to benefit the overall health of First Nations peoples.
A new study published in the British Journal of Sports Medicine found that resuming non-contact physical activity 72 hours after a concussion is safe for children and youth. The study, which involved 456 participants, showed that early return to physical activity can reduce symptoms and delayed recovery.
An international team led by the University of Ottawa has published findings on the importance of the enzyme GCN5 in maintaining muscle integrity. The study discovered that GCN5 plays a crucial role in boosting the expression of key structural proteins, notably dystrophin.
A University of Ottawa study found that trying to suppress emotions with a poker face or smile has little impact on mood and memory, contradicting past research. Instead, participants used alternative strategies like changing their perspective to cope with distressing moments.
The University of Ottawa's CoVaRR-Net has received a $9 million grant extension to continue its rapid research on COVID variants, including the Omicron variant. This renewed funding will allow researchers to accelerate their work and keep policymakers informed of their latest findings.
A novel vaccine, TOH-Vac1, replicates inside the body's cells and generates a powerful immune response in mice and monkeys. The vaccine is based on a strain of vaccinia virus used to vaccinate against smallpox and can be programmed to protect against multiple variants.
Researchers at the University of Ottawa have made a breakthrough in reversing memory deficits and slowing disease progression in female mouse models of Alzheimer's disease. The study found that activating a specific receptor was effective in treating females, who make up two-thirds of diagnosed cases.