A new study conducted at University of Utah Health found that zinc and folic acid supplements did not improve sperm counts or pregnancy rates in men. The researchers also noted a higher proportion of broken DNA in sperm among those who took the supplements, which could contribute to male infertility.
A study by University of Utah Health found that people with chronic illnesses turn to underground exchanges for medicines and supplies due to affordability and accessibility issues. Many participants donated or traded goods with family, friends, or strangers who couldn't get them through traditional channels.
Scientists at University of Utah Health have discovered new genetic elements that could help control obesity and metabolic disorders. Hibernating mammals have evolved short non-coding DNA snippets near genes linked to obesity in humans.
A study by University of Utah Health found nearly 33% of reproductive-age women with chronic conditions are using ineffective forms of birth control. Women with preexisting health problems are often missing out on crucial counseling about safe and effective birth control options.
A new study by University of Utah Health finds that doctors are less likely to ask routine gun safety questions in the home after mass shootings. Pediatricians added questions to screenings, but frequency dropped following incidents.
A new study published in eLife shows that children inherit a varying number of genetic mutations from their parents, with older fathers passing on more mutations to their offspring. The study analyzed data from 603 individuals from 33 three-generation families and found significant variability in mutation rates among families.
Researchers at the University of Utah Health have made a groundbreaking genetic discovery linking MacTel to HSAN1, revealing that toxic biomolecules deoxySLs cause damage to the macula. The study also found that lipid-lowering medication fenofibrate shows potential in protecting the retina from these biomolecules.
Researchers at University of Utah Health identified large immune cells containing oily droplets in the lungs of vaping patients, enabling faster diagnoses and shedding light on the mysterious condition. The discovery may lead to better treatment options and a deeper understanding of the illness's causes.
A new study reveals that up to 47.5% of patients who face life-threatening risks, such as domestic violence or depression, do not disclose this information to care providers. This phenomenon is linked to discomfort and a lack of trust between patients and providers.
Researchers use machine learning to analyze mouse behavior while foraging for food, identifying 71 reproduceable behavioral sequences as the underlying building blocks for more complex behavior patterns. The study reveals genetic influence over behavior and provides a new approach to understanding complex behaviors in humans.
Researchers at University of Utah Health identified a specific class of gut bacteria called Clostridia that prevents mice from becoming obese. Giving these microbes back to mice with an impaired immune system allows them to stay slim, suggesting a potential therapeutic approach for humans.
A multidisciplinary health care team approach increased the likelihood of survival for patients with refractory cardiogenic shock after a heart attack, with a 75% chance of survival at 30 days compared to 50%. The study found that team decision-making and collective wisdom improved patient outcomes.
Scientists at University of Utah Health and Merck Research Laboratories found that altering the production of ceramides can reverse insulin resistance and fatty liver disease in obese mice. By deactivating an enzyme called DES1, they lowered total ceramide levels, improving metabolic health.
Using cryo-EM, researchers captured the unfolding of proteins by Cdc48, a critical protein in recycling spent proteins. The study's results provide insights into the protein's structure and function.
A team of researchers at the University of Utah Health has identified TLE3 as a genetic switch that stops the conversion of white fat to beige fat cells, which burn energy more efficiently. Deleting TLE3 in mice resulted in enhanced energy expenditure and weight loss under cold conditions.
A recent study published in the Journal of the American Dental Association found that patients who received comprehensive oral care as part of their substance use disorder treatment had a significant increase in completing their treatment programs. The results show that participants who underwent FLOSS (Facilitating a Lifetime of Oral ...
A study published in Pediatrics found that children using the eAsthma Tracker app had improved asthma control, reduced emergency department visits, and increased school attendance. The app helps parents and doctors monitor symptoms and intervene early to prevent flare-ups, leading to better disease management and quality of life.
A new study at the University of Utah Health found that drug-induced death is the most common cause of pregnancy-associated death in Utah. Postpartum women who have previously or currently struggle with substance abuse are at greater risk of overdosing.
A joint study between University of Utah Health and Intermountain Healthcare found that inducing labor one week early costs the same as waiting for spontaneous labor. The study analyzed data from over 6,000 low-risk mothers and found that increased costs from longer hospital stays are offset by cost savings from avoiding additional tes...
Researchers at the University of Utah Health found that pairing music with pain medications improved analgesic outcomes by up to 90% in mouse models. The study showed significant reductions in inflammation and pain responses, suggesting a potential therapeutic strategy for managing pain.
A new study by University of Utah Health found that oral antimicrobial drugs excel in preserving parents' quality of life, costing significantly less ($7 vs $65 each day) and requiring less administration time (6 vs 90 minutes). This results in reduced time off work (30 vs 60 hours) and fewer missed days of school or daycare.
Researchers at University of Utah Health have developed a novel treatment that delays the onset of type 1 diabetes in mice and halts the progression of paralysis in multiple sclerosis models. The treatment targets misfunctioning immune cells, leaving normal immune cells intact.
A new method has been developed to measure the size of cholera outbreaks and identify geographic hotspots for the disease. The method uses six serum markers to detect recent infection, achieving an accuracy rate of 93 percent.
A population-based study of 49 individuals with autism who died by suicide found a significant increase in cumulative incidence rates compared to non-autistic peers. The majority of suicides occurred among women with autism, which was higher than the general population.
A state-by-state analysis reveals that melanoma survival rates differ substantially across the US, with states having more practicing physicians and higher percentage of Caucasians experiencing lower survival rates. The study highlights the need for targeted approaches to improve care and reduce deaths associated with melanoma.
A study identified 14 gene variants associated with polycystic ovary syndrome (PCOS), including three new variants. The findings suggest shared genetic architecture for different diagnosis criteria and links to other conditions like metabolic disorders, depression, and male pattern baldness.
Researchers used a massive dataset of over 100,000 individuals to identify constrained regions of genes that may underlie developmental disorders. These 'constrained' regions are intolerant to DNA changes and may cause disease when mutated, according to the study published in Nature Genetics.
Researchers at University of Utah Health found a 16 percent increased risk of miscarriage for women exposed to elevated air pollution levels, particularly nitrogen dioxide. The study suggests air quality is associated with adverse pregnancy outcomes and highlights the need for constructive solutions.
A study found that 60-80% of people surveyed lied about their diet and exercise habits, and failed to disclose medically relevant information. This can lead to inaccurate medical advice and compromised health outcomes.
A new study predicts achieving and maintaining lower blood pressure goals could prevent 3.3 million cardiovascular disease events, while earlier guidelines may only prevent 1.6 million, according to a recent analysis using population-based databases.
Researchers at University of Utah Health identified four gene changes linked to increased suicide risk in high-risk families. These findings may lead to new treatments for those who suffer from mental health issues.
Researchers at University of Utah Health discovered sustained connections between brain regions in individuals with autism. The study found that these prolonged connections may contribute to the symptoms of autism, including social dysfunction and difficulty shifting between activities.
Researchers found ADHD patients had a higher risk of developing Parkinson's and Parkinson-like diseases than non-ADHD individuals, especially those prescribed stimulant medications. The study suggests that the long-term health effects of ADHD and its treatment remain understudied.
Researchers analyzed Twitter conversations around OpenAPS, a DIY system combining off-the-shelf CGMs and insulin pumps, to understand its benefits and limitations. The study found that OpenAPS improved self-reported A1C and glucose variability while reducing daily distress and burden, but also raised concerns about safety and regulation.
Researchers have developed high-tech tools to identify the genetic cause of early childhood seizures, a rare disease that can lead to intellectual impairment and early death. The new approach uses computational tools to analyze genetic data and pinpoint changes in the genome responsible for disease development.
A study found that inducing labor at 39 weeks in healthy women reduces the need for cesarean sections and is as safe as waiting for spontaneous labor. The procedure may also lower the risk of preeclampsia and respiratory issues in newborns.
Nanoparticles have been modified to be absorbed through the lymphatic system, increasing bioavailability seven-fold. The new technique uses glycocholic acid as a cloak to help nanoparticles slip incognito through the small intestine lining.
A study by University of Utah Health scientists reveals that variation in the genetic modifier Baldspot can influence disease severity in retinitis pigmentosa. The research suggests targeting genes like Baldspot could lead to effective treatments against some disorders.
Researchers observed 283 protocol violations during 325 observations, including improper donning of personal protective equipment and errors in device handling. The study suggests re-evaluating transmission protocols and redesigning equipment to reduce self-contamination and infection transmission.
New research reveals a significant increase in organs available for transplantation due to the opioid epidemic. The study found that drug-overdose related deaths have led to a more than 10-fold increase in suitable donors.
Researchers found that music activates the salience network of the brain, which remains relatively functioning in individuals with Alzheimer's disease. The study suggests that personalized music programs may be an alternative route for communicating with patients who have lost contact with their environment.
A team of scientists at University of Utah Health uses animal genomes to identify regions that may control different diseases. They found elements linked to DNA repair, wing development and eye development in elephant, bat, dolphin and orca genomes, which could help in the study of cancer resistance and other health conditions.
A new study at the University of Utah Health found that removing cost obstacles allows women to access more effective contraceptive methods. The HER Salt Lake Contraceptive Initiative made all forms of contraception available, and participants could change methods at any time in the study, free of charge.
Researchers at University of Utah Health identified a mechanism that activates T cells, a key component of the immune system, in patients with persistent Lyme arthritis. This activation mechanism triggers inflammation and arthritis by producing inflammatory molecules that accumulate around the joints.
A new study published in the New England Journal of Medicine found that radiofrequency catheter ablation significantly lowers hospitalization and mortality rates compared to conventional drug therapies for atrial fibrillation in patients with heart failure. Catheter ablation restored regular heart rhythm by isolating pulmonary veins an...
A recent study by University of Utah Health researchers has discovered a novel protein, Arc, that resembles viral proteins and plays a significant role in cell-to-cell communication in the brain. The protein facilitates the transfer of genetic material between neurons, potentially altering our understanding of how memories are formed.
A new app developed by researchers at University of Utah Health aims to motivate type 2 diabetes patients to increase physical activity. The interactive simulation tool helps patients understand the impact of exercise on blood sugar levels, leading to increased motivation and plans for more exercise.
A study by University of Utah Health and Intermountain Healthcare found that bad air quality in the region causes more than 200 pneumonia cases each year, with older adults being particularly vulnerable. The research also estimates that improving air quality could save up to $1.6 million in healthcare costs annually.
Researchers at University of Utah Health have found a way for cells to destroy viruses without harming themselves. The study reveals how the protein Dicer, which is part of normal cell function, uses a different mechanism to process viral dsRNA.
A new study analyzed breast cancer tumor samples over time, revealing common characteristics among treatment-resistant tumors. The research aims to understand tumor changes in real-time to adjust treatment accordingly.