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Washington University in St. Louis


New technology offers pathways to finding treatments for kidney disease

Researchers at Washington University have developed a hydrogel system that preserves biochemistry and mechanical environments of cultured podocyte cells. This allows researchers to identify new ways to control mechanisms used by cells to heal themselves, potentially leading to therapies for currently incurable diseases.

SourceWashington University in St. Louis·JournalScience Advances·TypeExperimental study·DateAug 31, 2022

Distress leads to higher COVID vaccine rates, less adherence to distancing guidelines

A new study found that people experiencing anxiety or depression during the pandemic were more likely to get vaccinated, but less likely to follow distancing guidelines. The researchers suggest that a gentler approach may be warranted, focusing on the benefits of vaccination for others, to encourage behavior change.

SourceWashington University in St. Louis·JournalFrontiers in Psychology·TypeSurvey·DateAug 25, 2022

Sugar metabolism is surprisingly conventional in cancer

Researchers at Washington University in St. Louis found that cancer cells metabolize glucose in their mitochondria, following conventional biochemical patterns. The study suggests that limiting glucose uptake may not be an effective strategy to target cancer cells, and glucose metabolism may need to be reevaluated as a therapeutic target.

SourceWashington University in St. Louis·JournalMolecular Cell·TypeExperimental study·DateAug 15, 2022

One-hit wonder: How awards, recognition decrease inventors’ creativity

Research from Washington University in St. Louis found that awards and recognition can temper creativity by making producers feel threatened by the prospect of compromising their identity with mediocre work. This phenomenon is particularly pronounced among first-time producers, who are more likely to stop producing altogether if they f...

SourceWashington University in St. Louis·JournalJournal of Applied Psychology·TypeExperimental study·DateJul 14, 2022

New structure found in cells

A research team, led by Rohit Pappu and Anthony Hyman, found that protein molecules form dynamic clusters at low concentrations, which have structures that encode function. This discovery challenges the long-held assumption that there is no further structure underlying biomolecular condensates.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJul 12, 2022

New model shows Earth’s deep mantle was drier from the start

A new study suggests that Earth's deep mantle was drier than initially thought, with a water concentration 4-250 times lower than the upper mantle. This finding challenges the assumption that the mantle was uniform from its formation and may have prevented mixing within the mantle.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateJul 11, 2022

Social interactions tied to sense of purpose

Research from Washington University in St. Louis finds that positive social interactions are associated with a greater sense of purpose in older adults, particularly those who are retired. The study suggests that the quality of relationships and social connections play a significant role in shaping one's sense of purpose.

SourceWashington University in St. Louis·JournalAmerican Journal of Geriatric Psychiatry·TypeData/statistical analysis·DateJul 7, 2022

Study points to Armenian origins of ancient crop with aviation biofuel potential

Research from Washington University in St. Louis reveals that camelina, an ancient oilseed crop, may have been more important and widespread than previously thought, with origins in the Caucasus region near present-day Armenia. The study's findings support breeding programs to improve this crop for biofuels applications, highlighting i...

SourceWashington University in St. Louis·JournalAmerican Journal of Botany·TypeExperimental study·DateJul 5, 2022

The space between us

A study from Washington University in St. Louis highlights the importance of spatial aspects of biodiversity for healthy forest functioning. The research shows that tree beta diversity, a measure of site-to-site variation in species composition, is stronger than other components of biodiversity at larger scales.

SourceWashington University in St. Louis·JournalEcology·TypeObservational study·DateJun 1, 2022

Lew lab sheds new light on cell membranes

Researchers at the Lew lab have created a novel hardware and algorithm that enables visualization of cell membranes and molecular motions in six dimensions. This breakthrough allows for the observation of 3D structures with additional information on molecular orientation, providing new insights into biological systems.

SourceWashington University in St. Louis·JournalOptica·TypeComputational simulation/modeling·DateMay 26, 2022

Long COVID poses risks to vaccinated people, too

A new study found that vaccinated people with mild breakthrough COVID-19 infections can experience debilitating long COVID symptoms. Vaccination reduced the risk of death by 34% and long COVID by 15%, but not all manifestations were prevented. Researchers emphasize the need for additional layers of protection to mitigate risks.

SourceWashington University in St. Louis·JournalNature Medicine·TypeData/statistical analysis·DateMay 25, 2022

When more complex is simpler: ‘Coarse-graining’ can help scientists understand complex microbial ecosystems

A new modeling framework suggests that some microbial ecosystems are more easily understood through coarse-graining, which involves omitting details. This approach could help biologists study microbes in their natural environments, rather than isolating them in a petri dish.

SourceWashington University in St. Louis·JournalPhysical Review X·TypeComputational simulation/modeling·DateMay 16, 2022

Demographics, not bias, best predict traffic stops

Research from Washington University in St. Louis found that counties with a higher proportion of white residents have stronger anti-Black/pro-white attitudes, leading to larger disparities in traffic stops. The study suggests that racial demographics are a more reliable predictor of traffic stop discrepancies than racial biases.

SourceWashington University in St. Louis·JournalPsychological Science·TypeData/statistical analysis·DateMay 13, 2022

Nonlethal parasites reduce how much their wild hosts eat, leading to ecosystem effects

A study led by Washington University in St. Louis found that nonlethal parasitic infections reduce herbivory rates and trigger trophic cascades impacting plant communities. The research used a mathematical model and global meta-analysis to highlight the ecological consequences of common parasitic infections in wild animals.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateMay 9, 2022

Perception matters: How fear about crime impacts presidential approval

A recent study published in Public Opinion Quarterly found that anxiety about crime is a key predictor of presidential approval, with individuals who believe crime has worsened being more likely to punish presidents for it. The researchers also discovered that racial differences play a significant role in how Americans hold presidents ...

SourceWashington University in St. Louis·JournalPublic Opinion Quarterly·TypeData/statistical analysis·DateApr 18, 2022

Global instability and the timing of Russia’s attack on Ukraine

Research by David Carter and Scott F. Abramson suggests territorial conflicts tend to emerge when great powers are embroiled in crisis, creating opportunities for revisionist states like Russia to make aggressive moves. The study found over 60% of European territorial claims were made during the most unstable years after 1815.

SourceWashington University in St. Louis·JournalInternational Organization·TypeMeta-analysis·DateMar 17, 2022

Big data arrives on the farm

Glenn Stone's analysis reveals how precision agriculture tools, such as detailed soil mapping and autonomous vehicles, can erode peasants' ability to self-manage their communities. Small farmers may face a paradigm shift in lifestyle and subsistence, with increased dependencies on external commercial services.

SourceWashington University in St. Louis·JournalJournal of Agrarian Change·TypeObservational study·DateMar 1, 2022

Predicting the chaos in Tourette Syndrome tics

Researchers have replicated and expanded on previous work to show that tics associated with Tourette syndrome have a fractal pattern, which can predict disease severity. This discovery could lead to a diagnostic tool for doctors to analyze tic patterns and diagnose patients with Tourette's

SourceWashington University in St. Louis·JournalJournal of The Royal Society Interface·TypeComputational simulation/modeling·DateFeb 23, 2022

COVID-19 survivors face increased mental health risks up to a year later

Research reveals that people who have had COVID-19 are more likely to experience mental health problems, including anxiety, depression, and substance use disorders, within a year after recovery from the virus. The study found that COVID-19 survivors were 60% more likely to suffer from mental health problems than those who were not infe...

SourceWashington University in St. Louis·JournalThe BMJ·TypeData/statistical analysis·DateFeb 16, 2022

Research demonstrates importance of consistent branding in political television ads

A study by Washington University in St. Louis found that slant and consistency of messages in national television ads significantly impact online word-of-mouth chatter and candidate preference. Consistency with the primary message is crucial, even for more partisan messages, suggesting that campaign strategies should focus on building ...

SourceWashington University in St. Louis·JournalQuantitative Marketing and Economics·TypeContent analysis·DateFeb 9, 2022

COVID-19 infections increase risk of heart conditions up to a year later

A recent study found that COVID-19 infections can lead to serious cardiovascular complications, including heart attack, stroke, and coronary artery disease, even among previously healthy individuals. The risk of these complications remains high for up to a year after infection, highlighting the importance of post-infection care.

SourceWashington University in St. Louis·JournalNature Medicine·TypeData/statistical analysis·DateFeb 7, 2022

Heat conduction important for droplet dynamics

A team of engineers found that thermal conduction is the most prominent form of heat transfer during droplet impact on smooth surfaces, influencing cooling efficiency and droplet behavior. Heat conduction also affects droplet dynamics on rough surfaces, leading to lower heat transfer rates.

SourceWashington University in St. Louis·JournalExperimental Thermal and Fluid Science·TypeExperimental study·DateJan 6, 2022