A Wayne State University team is investigating possible determinants of adult-onset diseases like diabetes and atherosclerotic heart disease. The study aims to understand how sulfotransferase enzymes might impact drug efficacy, environmental carcinogens and metabolic processes.
Wayne State University leads a two-and-a-half-year study on the imagination of high-speed rail in America, examining what motivates decision makers and users to champion or use trains. The research aims to understand how railway futures are shaped by urban growth plans and transportation visions.
A Wayne State University professor has received a nearly $1.7 million grant from the National Institutes of Health to investigate proteasome and parkin as potential pharmaceutical drug targets for treating methamphetamine-abuse related neurotoxicity.
Scientists at Wayne State University are working to identify a chemical found in algae that may inhibit spawning in invasive zebra and quagga mussels. The research aims to develop an ecological-scale control strategy to disrupt reproduction and reduce mussel populations.
Dr. Ed Cackett has received a $550,000 NSF CAREER Award to study neutron stars and accretion in binary systems. He will also develop a program to bring solar telescopes to local schools, enhancing hands-on science education.
Traffic engineers at Wayne State University suggest metered roundabouts, or 'super circles,' as a solution to alleviate rush-hour congestion and enhance safety in the US. The proposed system utilizes stop lights to control peak hour traffic flow, reducing capacity issues and promoting safer intersections.
Researchers identified a single gene, Ultrabithorax (Ubx), responsible for leg and wing development in honeybees. Ubx represses the development of bristles on hind legs, creating a smooth surface for packing pollen, which is absent in queens.
The FDA has approved a new multiple sclerosis treatment regimen developed at Wayne State University, which involves injecting Copaxone at a higher dose but fewer times per week. The study demonstrated that this dosing regimen is effective and safe, with reduced relapse rates and improved tolerability.
Researchers at Wayne State University have discovered a potential way to improve lipid profiles in hemodialysis patients, which may prevent cardiovascular disease. Vitamin E supplements improved patients' triglycerides and HDL cholesterol levels compared to placebo groups.
Physicists at Wayne State University have observed 'charm mixing' in particles, a rare process where charm quarks change into their antiparticles. The discovery could reveal new insights into the universe's matter-antimatter imbalance.
A recent study published in the Journal of Nutrition & Metabolism found that algal extracts from Health Enhancement Products, Inc. improved plasma cholesterol profile despite a hypercholesterolemic state induced by a high fat diet. The extracts increased 'good' cholesterol levels and decreased 'bad' cholesterol concentrations.
A collaborative project between five Michigan universities aims to increase the academic success of underrepresented minority graduate students and postdoctoral scholars in STEM fields, as well as women graduate students. The project will strengthen mentoring relationships and engage students in interdisciplinary learning communities.
A team of Wayne State University researchers identified transforming growth factor β (TGFβ) signaling as a major pathway affected by hyperglycemia in DM corneal epithelial cells. Adding TGFβ3 to the wound accelerated epithelial wound closure, providing new treatment options for diabetic wound healing.
Wayne State University has licensed an intellectual property portfolio claiming composition of matter and methods of use of novel analogs and derivatives of the green tea flavonoid EGCG. The collaboration, involving Q. Ping Dou and Tak-Hang Chan, aims to develop novel approaches for cancer management and related conditions.
Researchers explore genetic and epigenetic factors contributing to racial disparities in prostate cancer risk and progression, focusing on MicroRNAs as potential biomarkers.
Researchers at Wayne State University have made a breakthrough discovery in the inflammatory stress mechanism driving rheumatoid arthritis. A specific IRE1a inhibitor was identified to prevent arthritis in animal models, offering new hope for treating this autoimmune disease.
A Wayne State University researcher is studying the effects of exercise on a process that plays a critical role in insulin signaling within skeletal muscle. He aims to identify molecular mechanisms responsible for improved insulin action after exercise and provide novel targets for preventing and treating type 2 diabetes.
The project will provide state-of-the-art training in modern, high-quality image-guided radiotherapy, increasing productive research and improving cancer patient care. Researchers from various disciplines will benefit from the six-day workshop, lecture and exercise-based course.
A recent study published in The Review of Higher Education found that followers play a crucial role in shaping organizational leadership practices. Through grounded theory research, Dr. Michael Owens discovered that students' participation in program leadership is not just about receiving benefits but also about giving back to the orga...
Wayne State joins other universities in improving STEM teaching methods to support high-talented students and increase graduation rates. The project aims to enhance faculty skills and track student progress to address attrition from STEM majors.
A Wayne State University team is working on a technology that can quickly and significantly reduce the emission of mercury and other toxic substances by power plants into the Great Lakes basin. The Locational Emissions Estimation Methodology (LEEM) technology, which was previously supported by the Great Lakes Protection Fund, will be r...
Wayne State University has received a $200,000 National Science Foundation grant to develop an undergraduate certificate program in nanoengineering. The program aims to prepare students for flexible employment opportunities and provide them with hands-on knowledge of cutting-edge technologies.
A research team led by Wayne State University aims to update the Highway Capacity Manual with the Michigan left turn design, enabling its adoption by other countries. The project will develop equations, text, and software for four alternative designs, improving traffic flow and safety.
The National Science Foundation has awarded Wayne State University a $25,000 planning grant to develop a strategic plan for a field-based water research center. The center, known as HEART, will focus on urban systems and the environment along the Huron-to-Erie corridor, impacting over 4 million people.
Researchers used fMRI to investigate the neural origins of hot flashes in postmenopausal women. They found that activity in brain regions like the brain stem and insula rises before and after the hot flash, respectively. The study provides novel insights into the complex brain mechanisms underlying this common menopause symptom.
Eight Wayne State University undergraduate nursing students are gaining unique insight into the research field through a $40,000 NIH grant. The program provides skills and experiences not offered at the undergraduate level, with the goal of attracting nursing students to doctoral education earlier.
A study by Wayne State University researcher James A. Rowley found that African-American men are more likely to experience severe sleep apnea, especially in younger age groups. The study controlled for body mass index and other factors, revealing a racial disparity in sleep apnea severity.
Two Wayne State research grants totaling $1.8 million focus on addressing obesity-related diseases and developing environmental health leadership, aiming to improve community health and economic vitality in Detroit.
Researchers found a conserved phospholipid enzyme, PIKfyve, crucial for insulin signaling in muscle cells, leading to glucose intolerance and insulin resistance. The study's mouse model exhibits metabolic defects similar to human prediabetes, offering new insights into treating these conditions.
The Wayne State University REU program provides funding for 10 students to work with faculty mentors on cutting-edge research projects in astrophysics and particle/nuclear physics. The program aims to give students a real-life research environment and contribute to ongoing research projects.
Researchers analyzed soil lead in an urban garden plot and found highly variable concentrations across the 49x98 foot garden. A prominent hotspot was detected in the northwest corner, where a paint shop had been located, exceeding the EPA's 400 ppm threshold for safe levels.
Researchers at Wayne State University are conducting a comprehensive study on the impacts of differential speed limits for cars and trucks on Michigan's state freeways. The study aims to determine whether raising truck speed limits would improve safety or have negative effects on air quality, pavement quality, and freight operations.
Wayne State University has received a second year of funding from the New Economy Initiative to expand its Technology Commercialization Office's efforts. The university will use the grant to enhance marketing tools and licensing staff, increasing the availability of WSU intellectual property assets to industry and venture capital.
A Wayne State University researcher found that affective commitment, or feeling loyal and proud of an organization, is the most desirable type. The study also showed that continuing commitment, driven by salary and benefits, can lead to employees staying too long due to high costs.
A Wayne State University researcher has developed a new technique called LOBOT that provides accurate, real-time positions for small ground robotic vehicles. The technique combines elements of common localization schemes and uses a hybrid approach with infrequent GPS use, a 3-D accelerometer, and motor rotation sensors.
Researchers have developed a new technique to improve the use of nanoparticles as a drug delivery system. The study found that smaller particles degrade faster in the body than predicted by in vitro measurements. By understanding this degradation, a mathematical model can be developed to optimize nanoparticle-based therapeutic systems.
A recent study published in Clinical Gerontologist found that older adults with high levels of depression and low social needs fulfillment are more likely to experience financial fraud. The study, which included 4,440 participants, revealed a 226% increase in fraud prevalence among the most psychologically vulnerable population.
Advaita, a Wayne State University startup, is participating in the new Michigan I-Corps program to turn its biotechnology innovation into commercial opportunities. The company aims to streamline drug-discovery methods, saving time and money for academia and pharmaceutical industries.
Researchers are working on a technique that can help identify and treat cancer tumors using manganese-enhanced magnetic resonance imaging (MEMRI). The goal is to guide and individualize treatment based on the presence of specific calcium channels in tumors.
A study published in the Canadian Journal of Criminology and Criminal Justice found that a common methodological practice, called capping, undercounts violent crime by 87% and household crime by 36%. The researchers suggest updating this technique to yield more accurate crime reporting.
Researchers analyzed survey data from 200 servers in 18 restaurants, finding that sensitivity to demographic differences predicted service levels. The study highlights the problem of poor service to African-American customers and suggests a solution by promoting tipping norms for specific levels of service quality.
A new study defines 'sudden exhaustion syndrome' as a distinct condition affecting cancer patients undergoing treatment, characterized by intense and prolonged fatigue. The research aims to enhance recognition and management of this often-overlooked symptom among oncology professionals.
A new US patent application allows for methods of restoring visual responses using optogenetic compounds, covering channelrhodopsin and halorhodopsin variants. The approved patent will substantively expand RetroSense's IP estate, providing broad protection for their gene therapies.
A Wayne State University study found seasonal fluctuations in blood lead levels among children are linked to resuspended dust contaminated with lead. The research, based on nine years of data from over 367,000 children, highlights the need for improved controls to prevent lead exposure.
Wen Li, assistant professor of chemistry at Wayne State University, has been awarded a $50,000 Sloan Research Fellowship for his innovative research on chemical reactions. This prestigious fellowship recognizes Li's achievements and potential as a rising star in scientific leadership.
Amar Basu's techniques enable rapid testing of biological liquids with nanoliter-picoliter volumes, reducing costs and improving assay speed. His projects focus on controlling droplet motion using lasers and sorting droplets based on chemical composition without labels.
A Wayne State University researcher has identified characteristics in benign breast disease associated with future cancer risk in African-American women. The study found that women with proliferative breast disease with atypia were three times as likely to develop breast cancer.
A Wayne State University researcher has developed a mathematical model-based methodology to estimate the optimal amount of time spent developing a product, as well as its cost, in overlapped product development. The approach could reduce product definition time by up to 50% and improve critical thinking.
A new study led by Wayne State University will aim to develop methods for better identifying women at increased risk for stroke. The research aims to educate doctors on how to follow recommended guidelines to identify these patients, leading to improved treatment and screening rates.
A Wayne State University researcher is evaluating the effectiveness of a 14-week text message-based behavioral intervention targeting Type 2 diabetes and its risks. The program, txt4Health, delivers tailored messages to users based on their individual risk for developing Type 2 diabetes.