A Wayne State University researcher is working on a new method to calculate the odds of structural failure in complex engineering structures. The goal is to achieve greater consistency within a structure while maintaining feasible computational costs. This approach has wide-ranging implications for various fields, including electrical,...
A Wayne State University researcher is studying the signaling process that triggers breast cancer transformation. The objective of his three-year study is to evaluate the potential roles of two small proteins in breast cancer progression.
A Wayne State University study shows that soybean compounds can make radiation treatment of lung cancer more effective while helping to preserve normal tissue. The compounds, known as isoflavones, block DNA repair mechanisms and molecular survival pathways in cancer cells, making them more vulnerable to ionizing radiation.
A Wayne State University study found that early research on cellphone conversations and crash risk may have overestimated the relative risk of conversation. Using GPS data, researchers tracked drivers over 400 days to find little driving consistency between control days, reducing the apparent risk of cellphone conversation.
Researchers at Wayne State University, Mayo Clinic and Johns Hopkins have developed a targeted drug delivery system using nanoparticles called dendrimers. This system reduced neuroinflammation in the retina and protected vision by preventing injury to photoreceptors.
A Wayne State University researcher is using zebrafish to study the spread of cholera and develop new treatments. The bacteria, Vibrio cholerae, can cause severe diarrhea and death if ingested by humans.
A Wayne State University physician is working to develop an outcome measurement that accurately reflects Charcot-Marie-Tooth disease progression in children. She aims to identify quality-of-life measures that can track changes in scores over time, enabling the evaluation of treatment effectiveness.
A team of Wayne State University researchers will investigate how fetal alcohol spectrum disorders affect infant numerical processing using event-related potentials. The study aims to improve diagnosis and treatment for children with FASDs, a condition with long-term effects on neurocognitive development.
A Wayne State University research team is working on a roadmap for identifying novel therapeutic targets to restore function to the mutated CFTR protein in cystic fibrosis patients. The goal is to alleviate severe lung and bowel problems associated with the disease.
Researchers at Wayne State University will study a novel antibiotic, daptomycin, to treat vancomycin-resistant Enterococcus (VRE) infections and decrease mortality. The goal is to determine the optimal doses of daptomycin to achieve greater bactericidal activity and prevent resistance.
A Wayne State University researcher is conducting studies to understand the differences in marijuana use among three subgroups of HIV-positive patients. The goal is to address knowledge gaps and inform decision-making at a state level, potentially guiding treatment and policy.
Researchers developed a novel indirect screener to detect recent drug use in at-risk post-partum women, proving more sensitive than alternatives. A brief, computer-delivered intervention aims to motivate behavioral change without presuming drug use, showing promise for improved detection and treatment.
Researchers at Wayne State University are developing a computer-delivered intervention to screen for and reduce alcohol use among pregnant women, with the goal of improving fetal health outcomes. The study aims to evaluate the effectiveness of handheld mobile devices and anonymous self-interview formats in identifying at-risk drinkers.
A Wayne State University researcher is using a three-year grant to examine the links between stress and drug use in heroin users. The study aims to understand how pharmacologically induced stress affects decisions to seek money or drugs.
Researchers at Wayne State University developed a novel gene therapy approach to restore vision in people with age-related macular degeneration and retinitis pigmentosa. A license agreement has been signed with RetroSense Therapeutics, paving the way for Phase I clinical trials.
A five-year federally funded effort aims to increase the number of local high school girls who enter college prepared to study health-related science, technology, engineering and mathematics (STEM) disciplines. The intervention comprises summer academies, academic year cafes, and continuous mentoring support.
The study will investigate the impact of risky family environments on asthma morbidity in children aged 10-15 using an innovative home-based naturalistic assessment tool. The research aims to determine if asthma morbidity increases due to avoidant coping behaviors and poor management of asthma treatment.
A Wayne State University professor is developing multifunctional therapeutic agents to slow Parkinson's disease progression and alleviate symptoms. The research aims to promote survival of dopamine neurons, which degenerate in the disease.
Researchers are developing a computer-delivered intervention to increase parental motivation and adolescent engagement in diabetes care. The study, targeting urban African American youth, aims to address poor health outcomes related to diabetes management.
Two Wayne State University research groups will lead projects on reducing driver distraction and improving the safety of children, teens, seniors, and pedestrians. The Collaborative Safety Research Center will invest $50 million over five years to enhance vehicle safety.
Wayne State University researcher Jeffrey Ram is using EPA grants to develop effective ballast water treatment systems and an early warning system for invasive species in the Great Lakes. The goal is to minimize the impact of existing invasive species and prevent new ones from entering the lakes.
Researchers aim to clarify the role of alpha-synuclein in spinal muscular atrophy (SMA), a genetic disease causing muscle weakness and degeneration. A better understanding of SNCA's role may lead to new therapies for SMA, potentially identifying useful disease markers and advancing neuromuscular disease research.
A Wayne State University-led study found that mother-son relationships with high conflict and low warmth during childhood can lead to delinquent behavior in adolescence. Conversely, close relationships between mothers and sons are linked to better peer relationships.
Wayne State start-up company NextCAT has received a Phase II Small Business Innovation Research (SBIR) award from the National Science Foundation. The $498,830 grant will support the commercialization of a biofuel catalyst technology that enables cost-effective biodiesel production using low-cost feedstocks.
Peter Savolainen's study found substantial progress in analyzing injury severity data, despite methodological issues. Researchers are developing statistical models to consider various factors impacting injury severity, including driver-, weather- and roadway-related variables.
A recent NIH award of $1.39M will support a study led by Dr. Lori A. Pile to investigate the alteration of chromatin structure during cell division, which is crucial for normal cell growth and cancer development. The findings aim to refine cancer treatments currently undergoing clinical trials.
A Wayne State researcher has discovered an antibiotic that can prevent and treat aseptic loosening, a condition where surrounding bones disintegrate after prosthetic joint surgery. The antibiotic, erythromycin, can be administered directly at the site of bone breakdown, reducing side effects associated with long-term oral use.
The NIH grant will support Wayne State's Initiative for Maximizing Student Development (IMSD) program, which provides personalized experiences for undergraduate and graduate students. The program has already supported over 700 students, with many going on to complete advanced degrees.
A Wayne State University researcher has received a $475,000 grant to develop graphene-based neural implants that could improve the quality of life for millions. The technology aims to overcome limitations of current implantable devices by using a flexible material and biodegradable backing.
Kezhong Zhang is studying CREBH's role in regulating NAFLD through a $1.7 million NIH grant. He aims to understand how CREBH controls fat production and digestion, with implications for preventing and treating NAFLD.
Researchers at Wayne State University are investigating the link between toxicity of fatty acids and obesity-diabetes connection. They're developing sensors to visualize fatty acid production and signaling in live cells, aiming to create new anti-obesity therapeutics.
A recent analysis by Wayne State University's Seniors Count! project reveals that 37% of Michigan's seniors live at or below basic economic security. This 'invisible poverty' affects many middle-class residents, who struggle to afford basic expenses like food, housing, and healthcare.
A study by Jeffrey Martin found that social and environmental factors like classmate support and confidence play a crucial role in determining physical activity levels among underserved children. The study also revealed that girls are less likely to engage in physical activity than boys, highlighting the need for targeted interventions.
A study by Wayne State University researchers found that self-rated physical ability tops injury severity as a determining factor of health ratings in adults with spinal cord injuries. The study suggests that people with disabilities can still rate their health as excellent or good despite being confined to a wheelchair or paralyzed.
Na Zhu, a PhD student at Wayne State University, has received the American Tinnitus Association Student Research Grant Program award. Her innovative 3D diagnostic system aims to pinpoint neural network activities in the brain's auditory structure.
A recent study published in the journal Evolution proposes that sex may not promote genetic diversity as previously thought. Instead, its primary function is to maintain a species' genome context and prevent macroevolution, allowing for microevolution to occur.
Researchers found clinical and personal barriers hinder mammography screening among African-American women. Interventions can be effective by educating providers to build trust, offer culturally appropriate health education, and make referrals.
A recent study published in Rehabilitation Psychology found that TBI victims who feel a strong connection to a higher power experience better emotional and physical rehabilitation outcomes. Social support also played a significant role in positive health outcomes.
Researchers at Wayne State University have been awarded a $330,000 NSF grant to develop a 3-D neural probe that can suppress tinnitus by electrically and chemically stimulating neurons. The probe will enable the integration of micro-channels for neurotransmitter-based chemical stimulation and local drug delivery.
Researchers aim to determine how vitamin D affects cardiac structure and function, vascular function, and left ventricular hypertrophy in blacks with hypertension. The study could identify vitamin D as a safe and effective therapy to stop or reverse cardiac ravages caused by high blood pressure.
Hongwei Zhang aims to develop reliable wireless networks for vehicular control and other applications. He addresses challenges in scheduling transmissions and sensing information between devices.
Researchers at Wayne State University have found a new method to identify children with major depressive disorder (MDD), setting them apart from both healthy children and those with obsessive compulsive disorder (OCD). Cortical thickness in the brain was used as a key factor, revealing distinct differences between MDD patients and heal...
Wayne State doctoral student Keith Zabel has been awarded a prestigious NSF Graduate Research Fellowship to study the impact of racial bias on mentorship. His research aims to determine if prejudice towards black mentors affects protégé outcomes, with potential implications for mentoring literature.
Wayne State University students will explore advanced vehicle solutions to minimize petroleum usage and reduce emissions through research collaboration with industry. The university was chosen as Michigan's sole participant in EcoCAR 2, a three-year competition that aims to inspire and educate the next generation of automotive engineers.
A Wayne State University School of Medicine researcher has developed a potential vaccine for Chlamydia, targeting the disease's leading causes of blindness and infertility. The technology demonstrates a successful vaccine effect in an animal model, paving the way for human trials and potentially significant public health benefits.
A WSU study evaluates the use of technology in Canadian K-12 distance education, finding that all provinces have implemented some form of distance learning. The study also highlights Alberta's blended approach to online learning, improving student outcomes.
A new study aims to improve the care of African Americans with cancer pain by providing a five-week program called Power Over Pain - Coaching or POP-C. The program addresses the challenges to pain care in this urban community and seeks to reduce suffering, distress, and burden among patients and caregivers.
Researchers at WSU aim to uncover the biological cause of Gulf War Illness by studying genomic instability. High levels of chromosomal aberrations have been detected in GWI patients, similar to those found in cancer patients. The study may lead to a simple blood test for diagnosing GWI.
A Wayne State University study found that soy isoflavones can sensitize cancer cells to radiation while protecting normal tissue. The study demonstrated that soy isoflavones can block DNA repair mechanisms in cancer cells, leading to increased killing of lung cancer cells by radiation
A new method for preventing premature birth has been announced, showing that treating pregnant women at risk with a low-cost progesterone gel can reduce the rate of early preterm delivery in women with short cervix by 45%. The study found that progesterone also reduced respiratory distress syndrome in premature babies.