Articles tagged with Research and Development
Researchers found that somatostatin interneurons can cause seizures when they go haywire, disrupting the brain's balance. The study identified a rare epilepsy syndrome and developed mouse models to understand the neurological dysfunction, paving the way for new treatments.
A novel computational platform called scAAVengr uses single-cell RNA sequencing to quickly evaluate viral vectors for delivering gene therapies to the retina with maximum efficiency and precision. This approach saves time and resources by identifying suitable candidates that can deliver therapy to affected parts of the retina accurately.
A new instrument at the Advanced Light Source enables simultaneous measurement of crystal structure and optical properties during perovskite synthesis. This allows for real-time monitoring of material quality and performance, leading to potentially more efficient solar cells.
A new study found that translocator protein 18 kDa (TSPO) correlates with worse survival outcomes in male glioblastoma patients compared to females. The variation in the protein's structure is associated with shorter overall and progression-free survival times, suggesting its potential as a prognostic biomarker.
The study identifies promising topics for scientific collaboration, including medicine, engineering, computer science, and agricultural sciences. BRICS Plus countries have significant growth potential in research and development, with some already ranking among the top 30 countries globally.
The study found that a stack pressure of 350 kilo Pascal increases lithium particle deposition in neat columns, improving stability and reducing the risk of short circuits. Additionally, partial discharge during cycling can also boost performance without affecting the solid electrolyte interphase structure.
A woman-owned spinout company, Chosen Diagnostics Inc, has received a $2.1M NIH grant to develop and commercialize a noninvasive diagnostic biomarker test for necrotizing enterocolitis. The test, called NECDetect, identifies 93% true positives and 95% true negatives in diagnosing the disease.
A new study examines vaccination misinformation on social media, revealing that fear-provoking messaging fuels its spread. The research team developed predictive models to identify true and false information on Twitter, categorizing messages as positive or negative cause-effect statements.
Researchers developed a program to target vaccinations using digital contact tracing technology, which can almost halve the number of vaccines required to bring the pandemic under control. The new program prioritizes individuals with the most contacts for vaccinations while keeping personal data private.
Rosalind Franklin University of Medicine and Science has been awarded a $2 million matching grant to develop and open state-of-the-art wet lab space for collaboration with industry partners. The funding will also benefit Lake County communities by attracting biotech companies and creating new jobs, internships, and training programs.
Researchers developed a simple screening tool for cervical myelopathy (CM) using machine learning and finger motion analysis with a non-contact sensor. The tool has shown high accuracy in detecting CM, outperforming specialist diagnoses based on physical findings.
Researchers developed PocketView, a display technology that shows basic information like notifications and time through fabrics, offering versatility and ease of use. The technology is relatively inexpensive and can be incorporated into existing devices, making it a potential game-changer in wearable tech.
Developed a highly efficient boiling immersion cooler using lotus metals, increasing critical heat flux from 200 W/cm² to 530 W/cm² or more. The technology is expected to solve the heat concentration problem of in-vehicle power semiconductors and be applied to CPUs for workstations and large-scale servers.
The CARE Consortium has received $42.65 million in new funding to follow athletes for up to 10 years after concussive injury, examining the impacts of head injuries on brain health. The study aims to validate advanced biomarkers and identify neurobiological pathways contributing to long-term negative consequences.
A new locally acting treatment aims to reduce the severity of post-transplant ischemia reperfusion injury (IRI) without affecting the immune system. The treatment targets specific neoepitopes exposed on injured donor organs, reducing the risk of organ rejection and improving transplant outcomes.
MUSC researcher Haizhen Wang receives R37 grant to investigate CDK6's role in T-cell acute lymphoblastic leukemia, a aggressive cancer. The research aims to understand how the immune system can be used to reduce leukemia progression.
Researchers at MIT develop RFusion, a robotic system that uses data from a camera and radio frequency antenna to locate and retrieve lost items. The system relies on RFID tags and machine learning algorithms to optimize the robot's trajectory and grasp the object.
A blockchain-based system allows leader robots to signal movements and add transactions to a chain, while malicious leaders forfeit tokens when caught in a lie. This limits the spread of incorrect information and enables follower robots to eventually reach their destination.
Dr. Gack's research focuses on identifying broad-spectrum antiviral drug targets and has implications for developing effective treatments against COVID-19 and other viral threats. The $5.6 million NIH grant will support her investigation into targeting human enzymes essential for virus replication.
The Army has pledged $5.2 million to Rice University's research on flash Joule heating, a process that turns waste into graphene and other valuable materials. The technology can recover precious metals from electronic waste and toxic metals from contaminated soil.
Researchers at IOCB Prague have developed a novel antibacterial material called NANO-LPPO that can prevent infection and facilitate treatment of skin wounds. The material combines lipophosphonoxins with a nonwoven nanotextile, which releases active substances in response to bacterial presence.
Glyscend Therapeutics has initiated a phase 1 clinical trial in Australia investigating an oral polymer therapy that improves glucose homeostasis with weight loss in nonclinical models. The therapy targets mechanisms underlying bariatric surgery and aims to replicate its benefits without the need for surgery.
Researchers at RIT have developed a new method for detecting superfluid motion that is minimally destructive, in situ, and in real-time. The technique uses laser light to detect the frequency of superfluid rotation, enabling scientists to study superfluids without disrupting their motion.
China's space transportation systems have made significant leaps in recent decades, with advancements in launch vehicles, propulsion systems, and artificial intelligence. The country aims to become a powerful space nation by the mid-21st century, with plans for manned missions to the Moon and Mars.
Scientists at Aarhus University are working on a nano-sized brain-inspired computer that can harvest its own energy, making it the smallest and most efficient AI system yet. The project aims to reduce power consumption by 12 orders of magnitude compared to modern supercomputers.
A team of NTU Singapore scientists developed a predictive computer model called NSGA-II, which proposed strategies to reduce COVID-19 infections and deaths by an average of 72%. The model recommended timely and country-specific advice on interventions such as home quarantines and social distancing measures.
A new, low-cost 3D-printed sensor can accurately detect and measure glyphosate levels in liquids with high sensitivity and specificity. The sensor uses nano-sized tubes and technology similar to glucose tests to detect the herbicide in orange juice and rice beverages.
Researchers developed an experimental device to improve blood sugar control in HI patients. The bihormonal bionic pancreas (BHBP) helps maintain stable glucose levels without human error in calculating doses.
Three Lehigh University faculty members received federal grants to study reading interventions, supports for students with disabilities, and teachers of students with autism. The projects aim to improve reading growth for students with intellectual and developmental disabilities.
Researchers developed WebFRIS, a web-based platform to provide socio-economic vulnerability analysis and simplify flood risk information. The tool can help formulate targeted solutions and enhance social capacity and resilience in flood-prone regions.
Researchers have developed an AI-powered tool, Roofpedia, to track sustainable roof adoption worldwide. The tool uses satellite images to gauge cities' green and solar roof penetration, with Singapore ranked third in solar roof coverage.
Researchers at Georgia Institute of Technology developed improved carbon membranes that can efficiently separate para-xylene from its siblings, reducing energy consumption by up to three times. The breakthrough could lower energy costs in producing commodity chemicals and fuels.
The Agency for Science, Technology and Research (A*STAR) has developed a Fluid-supported Liquid Interface Polymerization (FLIP) 3D printer that can rapidly print hydrogel structures with complex geometry. This approach addresses the key nutrient supply issue in bioprinting, enabling the rapid fabrication of complex geometrical shapes.
Researchers developed a method to overlay a virtual scale on acquired endoscope images in real-time, allowing accurate estimation of colorectal polyp sizes. The approach uses triangulation principles and minimal image processing, enabling cost-effective diagnosis without adding extra instrumentation.
A UNSW psychology researcher recommends a set of neurocognitive and mental health questionnaires to harmonize the assessment of long COVID patients. These tests can be used internationally and in various cultural settings to address key questions about the problem, including brain fog and dementia risks.
A new analytics platform, RDCA-DAP, will be launched to accelerate rare disease treatment innovation by hosting and standardizing rare diseases data. The platform is expected to empower patients and families to drive innovation in the field.
Researchers created a bionic arm that combines intuitive motor control with touch and hand movement sensation, enabling wearers to think and behave like a person without an amputation. The system's bi-directional feedback and control allowed study participants to perform tasks with similar accuracy as non-disabled people.
SECORE International's coral breeding technique shows significant success in closing the gap to scale for coral restoration, using floating mesocosms to produce thousands of coral recruits. The approach promotes genetic diversity and can help corals cope with climate change.
High-intensity focused ultrasound (HIFU) technology is being explored for its potential to destroy cancerous tumours while minimizing damage to healthy tissue. Researchers at the University of Waterloo have made significant progress in understanding how HIFU works on a cellular level, paving the way for future clinical trials.
Researchers at Virginia Tech have developed a scalable method to harvest exosomes from unpasteurized cow's milk, enabling the production of purified exosomes for oral drug delivery. The new protocol advances pharmaceutical applications for fragile drugs and opens up a wide range of clinical applications.
Researchers at Purdue University and Houston Methodist have developed a novel TB vaccine formulation that enhances T cell responses to combat tuberculosis. The new vaccine uses autophagy-mediated antigen presentation, showing promising results in improving immune response.
Scientists at Ural Federal University and RAS developed a technology to process metallurgical slag into valuable materials such as cast iron and Portland cement clinker. The technology eliminates the problem of environmental pollution by industrial enterprises.
Researchers investigated the link between state opioid prescription duration limits and changes in opioid prescribing. The study found that limiting initial opioid prescriptions may lead to a decrease in opioid-related overdose deaths, but also increase unnecessary hospitalizations.
Hailin Li, a WVU engineer, will lead a project to develop a software platform that simulates heavy-duty diesel engines with advanced after-treatment systems. The goal is to improve engine efficiency and reduce exhaust emissions, which will help cut greenhouse gases and pollutants from the transportation sector.
Researchers developed simple, low-cost legged robots that can link and unlink to accomplish tasks like gap traversal and stair climbing on uneven terrains. The robots use easily acquired off-the-shelf technology and a magnetic connector for docking and cooperative behaviors.
A new research project aims to assess the effectiveness of comprehensive social, environmental, and health promotion services in affordable housing settings. The study will track the impact of these programs on residents, building culture, and housing conditions over time.
Researchers developed a novel evidence-based material recommender system that predicts high entropy alloy formation without data descriptors, overcomes data bias and poor availability. The method recommends an FeMnCoNi alloy as the most probable HEA and successfully synthesizes it, confirming its validity.
Researchers created a polymer coating that releases Lasioglossin-III, an AMP with broad-spectrum antibacterial activity, targeting specific infectious bacteria and preventing airway complications. The coating demonstrated significant antibacterial activity and prevented bacterial adherence to the tube.
Researchers from NUST MISIS and international partners create a radar-absorbing polymer composite with excellent magnetic and microwave properties. The composite can absorb 99.9% of incoming electromagnetic radiation, making it suitable for EMI shielding applications in industries such as 5G networks and radar absorbing coatings.
Researchers found changes in erythrocyte morphology and nanoparticles on cell surfaces during radiation therapy, which may indicate treatment effectiveness or prognosis. The study suggests that analyzing these changes could lead to the development of a diagnostic method for assessing RT efficacy.
Researchers at UIC have received a $725,000 grant to develop an AI system that can help protect US Navy divers from waterborne bacteria, parasites, and other harmful pathogens. The system aims to provide real-time information on water conditions, allowing divers to make informed decisions about their mission.
Researchers at Children's Hospital of Philadelphia have developed a system that can fine-tune protein expression from gene therapy vectors, addressing the need for controlled dosing. The 'dimmer switch' uses alternative RNA splicing and an orally available small molecule to adjust levels of expression up or down as needed.
Researchers found that targeted behavioral science messages significantly increased COVID-19 vaccination registration among healthcare workers. The study showed a substantial increase in vaccine uptake after receiving personalized email nudges.
A new study reveals that increased lobbying spending leads to decreased customer satisfaction, which in turn reduces the effect of lobbying on firm value. Firms can mitigate this loss by adopting marketing-focused efforts, such as having a marketing CEO or spending more on R&D and advertising.
A new algorithm has been developed that can guide a quadrotor drone through a series of waypoints on a circuit, beating the fastest lap of two world-class human pilots. The algorithm generates time-optimal trajectories that fully consider the drones' limitations, resulting in faster and more consistent flight times.
USC researchers develop AI that can simulate human imagination by recombining learned knowledge of attributes. This technique enables controllable novel image synthesis, a key step towards overcoming the generalization problem in AI. The approach has potential applications in medicine, autonomous vehicles, and fairness in AI.
The new Quantum C100 detector enables radical simplification of microscope design, making cryoEM widely available and accessible. This will benefit society by increasing the democratization of cryoEM technology.
The article emphasizes the importance of integrating different disciplines and stakeholders in conservation efforts. Key findings include the need for increased funding and expert guidance for transdisciplinary research, as well as the benefits of such approaches, including improved data quality and innovation.
Researchers developed a computational cognitive model to explain how children integrate information during word learning. The model simulates what should happen when different information sources are combined in a rational way, and its predictions align well with real-world data.
A study developed a genetic risk score to predict adolescent idiopathic scoliosis (AIS) onset and severity. The score may help identify children at risk who could benefit from preventive treatments.