Articles tagged with Research and Development
The investigational vaccine targets both the spike and nucleocapsid proteins, producing neutralizing antibodies and inducing T cell responses against SARS-CoV-2. COH04S1 is being studied in Phase 2 trials for immunocompromised patients and as a booster for healthy adult volunteers.
Dr. Zhiqiang Lin has been awarded a $3.2 million NIH grant to investigate the roles of YAP and IRF2BP2 in the cardiac innate immune response, with the goal of reducing cardiac inflammation and promoting heart recovery after a heart attack.
Researchers develop detailed canine gait analysis method to evaluate harnesses, providing a more accurate fit for dogs. The new method could lead to improved comfort and safety for dogs wearing harnesses.
A new, touch-based device has been developed to ease anxiety in students by mechanically simulating breathing. The 'breathing' cushion was found to be equally effective at reducing anxiety as guided meditation in a study of 129 volunteers.
Researchers at Tel Aviv University have developed a unique detector using compressed xenon gas to detect axion-like particles, promising a breakthrough in finding dark matter. The new technology enables the exploration of previously inaccessible masses, constraining the properties of axion-like particles.
A team of UTSA researchers has developed an innovative inhibitor that blocks the effects of cytochrome P450 8B1, a key enzyme linked to cholesterol absorption and obesity. The treatment shows promise in reducing glucose levels without affecting body weight, offering potential relief from obesity-associated metabolic disorders.
Researchers developed a new imaging approach called VascuViz to visualize blood vessels at different spatial scales. The method enables detailed mathematical models and complementary images to clarify the role of blood flow in health and disease, advancing our understanding of tissues throughout the body.
Researchers at Chalmers University of Technology have developed a method to produce micro-supercapacitors, which can increase battery lifespan and enable fast charging. The new production process is scalable and could lead to significant environmental benefits by reducing battery recycling needs.
A novel ferroelectric tunnel junction (FTJ) synapse based on Ag/PbZr0.52Ti0.48O3(PZT, (111)-oriented)/Nb:SrTiO3 demonstrated 256 conductance states with satisfactory linearity and stability. The ON/OFF ratio was as high as 200, and an endurance of up to 10^9 cycles was achieved.
Scientists observe atomic magnetic field and origin of magnetism in iron atoms using Magnetic-field-free Atomic-Resolution STEM (MARS) and Differential Phase Contrast (DPC) method. This breakthrough enables research and development of various magnetic materials and devices.
The study reveals that seven indicators affect people's decisions, including ornament, material, and line, which influence heritage perception. A model can predict the heritage potential of a building by ordinary people.
A VA research team found increased risks of mental health disorders, including depression, anxiety, and sleep disorders, in individuals who had COVID-19 infection. The study analyzed medical records of nearly 154,000 patients with COVID-19 and compared them to over 11 million people without COVID-19.
Researchers at UC Davis MIND Institute found a novel gene linked to autism spectrum disorder in newborns. The study analyzed DNA methylation signatures in the placenta, which reflected fetal brain development and early autism diagnosis.
Researchers developed a new reagent-free detection technique for SARS-CoV-2 using Raman spectroscopy and machine learning. The method shows an accuracy of 80% in detecting COVID-19 infections from saliva samples, overcoming limitations of RT-PCR testing.
The University of Texas at San Antonio has established a San Antonio-based Coccidioidomycosis Collaborative Research Center (SA-CCRC) focused on developing therapeutics and vaccines against coccidioidomycosis. The center will support applied clinical research and house an extended network of experts from partnering institutions.
Researchers at the University of Illinois Chicago have developed a compound that may offer hope for pancreatic cancer treatment. The experimental compound, XP-524, has been shown to more than double the average survival time for mice with pancreatic cancer when combined with immunotherapy.
A mechanical RIS has been developed with high reconfiguration degree of freedom, low power consumption, and real-time dynamic control capabilities. It uses a robust control method to determine the rotation angle of each meta-atom and offers a new energy-saving and environmentally friendly alternative for wireless communications systems.
A collaborative research project on quantum technology has started on the International Space Station (ISS), utilizing ultracold atoms to conduct fundamental research and develop future quantum sensors. The BECCAL experiment is a multi-user platform open to international scientists, allowing them to test their ideas in practice.
The NIAID plans to identify prototype pathogens with potential to cause significant human disease, building a framework for rapid research and product development. The institute also focuses on priority pathogens known to cause significant human illness or death.
USC researchers develop highly accurate model to predict Covid-19 risk by combining anonymized cellphone location data with mobility patterns. The system shows a 50% improvement in accuracy compared to current systems, enabling targeted policy decisions at neighborhood or zip code levels.
Researchers from West Virginia University are developing a new composite transition joint using 3D printing to reduce stress on power plant systems. The goal is to increase the flexibility and reliability of thermal power plants.
The US healthcare system is failing to provide adequate care for traumatic brain injury (TBI) survivors, experts warn. A recent report recommends using a comprehensive classification system that incorporates the Glasgow Coma Scale score, CT scans, and blood tests to better assess the severity of TBI.
A new study by NYU Tandon professor Nikhil Gupta explores the recyclability of lithium-ion and lead-acid batteries, highlighting the need for a circular economy approach. While lead acid batteries have a high recycling efficiency, lithium-ion batteries pose significant challenges due to their rapidly evolving chemistry and cell design.
The collaboration aims to create an interoperable global data ecosystem for rare diseases, accelerating the development of new therapies. This partnership benefits patients, regulators, advocacy stakeholders, researchers, and industry, while expanding C-Path's global capabilities in collaborating on methodologies and technologies.
Researchers at Pusan National University have developed a new model using 'double Mellin transforms' and the 'method of dimension reduction' to accurately price vulnerable exchange options. The model provides an effective and accurate mathematical solution, enabling quick deployment without long calculations.
Researchers developed a software-based smoke dispersal simulation model to study prehistoric archaeology. They found that early humans placed their hearth at the optimal location in the cave, enabling maximum utilization of fire while minimizing smoke exposure. The study identified a 25sqm area as ideal for locating the hearth.
A new portable $51 testing kit can provide fast and reliable COVID-19 detection in resource-poor regions, refugee camps, and disaster zones. The non-invasive saliva sampling system uses a technique similar to PCR testing, with costs comparable to commercial tests.
Researchers at OHSU are developing a new approach to scientific imaging to study the dynamic organization of cells by examining how tiny molecules make cells work. The W. M. Keck Foundation has awarded $1 million to develop a one-of-a-kind imaging and computational system.
A novel plan to deploy smart transactive energy systems on the US power grid could reduce daily load swings by 20-44% and save consumers up to $50 billion annually. By coordinating with utilities, consumers can dynamically control big energy users like heat pumps and electric vehicle charging stations.
A new software uses pose estimation to track human motion with high accuracy, providing an objective assessment of motor function. The technology has the potential to revolutionize neurological care by enabling patients to record video that can be analyzed by their physicians remotely.
A new study finds a strong link between emissions taxes and increased R&D investments in high-polluting industries with knowledge spillovers. Manufacturers significantly boost R&D spending to adopt cleaner technologies and improve production efficiency without necessarily slowing economic growth.
A Korean research team created a DUV LED using hexagonal boron nitride (hBN), emitting strong UV light with low skin penetrability. The new material has higher luminescence efficiency and enables miniaturization, making it suitable for various applications.
A team of scientists from Gwangju Institute of Science and Technology developed a deep learning-based approach to predict SC2 battle outcomes by considering army composition and terrain type. The proposed model leveraged parameter sharing, enabling it to analyze complex factors accurately and make predictions.
Researchers at FAU are developing an affordable, disposable self-testing HIV-1 chip that can detect HIV from whole blood samples and measure viral load without refrigeration or skilled technicians. The technology aims to increase access to HIV testing and improve treatment outcomes in any setting.
Researchers have developed a new text-based analytics model that analyzes firms' tailoring of investments to their portfolio of products, using the four-stage product cycle. This framework provides insights into how firms exploit investment opportunities, including disclosure patterns and strategic alliances.
Researchers at Waseda University discovered a new protein isoform called Senp5S, which helps regulate Drp1 and mitochondrial dynamics during brain development. The study suggests a novel and vital role for post-translational SUMOylation in neuronal differentiation.
Researchers developed a color-coded test that quickly signals whether medical nanoparticles deliver their cargo into target cells. The tool, tested in mouse cells and living mice, assesses nanoparticle formulations on their ability to escape cellular defenses and reach the cell's interior.
A new technology developed by Aarhus University researchers uses sustainable biochar-based photocatalytic nanomaterial to break down PFAS into harmless substances. The process is powered by solar energy and produces non-toxic fluorides, CO2, and clean water.
Paderborn University to establish a three-node quantum network in real urban environment, utilizing standardized equipment and protocols. The initiative aims to enhance efficiency and stability of quantum communication systems.
Phoebe Lin's research establishes a gut-eye association in animal models, finding that certain interventions can enhance Tregs and decrease eye inflammation. Her five-year grant will investigate how intestinal microbes and the immune system can be rebalanced to treat uveitis.
Aston University's Aston Institute of Photonic Technologies has received a £100,000 grant to support its research in food and agri-tech. The new equipment will enable the development of cost-effective photonic technology for quality control in food processing and manufacturing.
Scientists at Sandia National Labs invent a new yardstick for benchmarking performance of quantum computers. The mirror-circuit method is faster and more accurate than conventional tests, revealing the true potential and limitations of quantum processors.
Researchers at MIT developed a selective separation process using sulfidation to target rare metals like cobalt in lithium-ion batteries. The approach reduces energy consumption and greenhouse gas emissions compared to traditional liquid-based separation methods.
Scientists developed an all-season smart-roof coating that automatically switches between cooling and heating, outperforming commercial cool-roof systems in energy savings. The technology uses vanadium dioxide to regulate its rate of radiative cooling, overcoming the problem of overcooling in winter.
A new device has been developed that converts sunlight into two promising sources of renewable fuels – ethylene and hydrogen. The researchers found that by optimizing the working conditions for cuprous oxide, a promising artificial photosynthesis material, they can create a more stable system.
Research comparing site-specific nutrient management approaches to existing farmer fertilization practices shows SSNM improves average rice yield by 644 kg/ha, increases profitability, and reduces N losses. SSNM also promotes better nutrient balance and considers micronutrients like zinc and iron.
The University of Central Florida researchers have developed an alcohol-based power source for cars and other technology that uses less fuel and produces fewer emissions compared to traditional fossil fuels. The ethanol fuel cell has achieved a maximum power density and operation time of over 5,900 hours, making it a promising alternat...
The Estée Lauder Companies has released its Green Score methodology to assess and measure the sustainability of ingredients and formulas based on green chemistry principles. The approach uses a quantitative tool to evaluate human health, ecosystem health, and environmental impact across its product portfolio.
Researchers discovered that blood stem cells use high-energy fatty acids from the body's fat stores to power up their response to infection. This finding could lead to new approaches in treating bacterial infections, particularly in vulnerable and older individuals.
Researchers developed an AI system to predict ICU admission for COVID-19 patients based on over 200 clinical data points. The system achieved greater than 95-per-cent accuracy in predicting ICU need for new cases and identified key factors driving its predictions.
A new study developed by researchers at Ohio State University Wexner Medical Center found that a simple, self-administered test can identify early signs of dementia sooner than the most commonly used office-based standard cognitive test. The Self-Administered Gerocognitive Examination (SAGE test) accurately identified patients with mil...
Researchers have developed a new two-photon microscope that provides subcellular resolution of multiple brain regions, enabling monitoring of neural circuitry in mammals. The microscope has the largest field of view and imaging speed to capture changes in neuron activity during behavior.
Researchers developed a new kind of organoid that grows both heart and gut cells together, mirroring their cooperation in embryonic development. This breakthrough could improve understanding of tissue communication and inform research into congenital disorders.
A new study published in the Journal of Experimental Medicine showed that a fast-tracked stroke drug, 3K3A-APC, protected mice from injury to the brain's white matter, a leading cause of dementia. The drug may also be effective in slowing down progression of cognitive impairment.
A new study found that research and development on chemistry and materials science were key factors behind the significant cost decline of lithium-ion batteries. The analysis revealed that over 50% of the cost reduction came from R&D activities, with chemistry and materials research being the primary contributors.
Researchers discovered that a specialized form of vitamin D can reduce inflammation caused by T cells in lung cells, which may be relevant to severe COVID-19. The study suggests that adding this concentrated intravenous metabolite to existing treatments could help patients recover from COVID infections.
A team of scientists from Tokyo University of Science has developed a machine learning-based tool to predict thermoacoustic oscillations in engines. The tool uses dynamical systems theory and can classify combustion into three states, identifying pressure fluctuations that indicate future combustion oscillations.
UArizona researchers created osseosurface electronics, a wireless device that grows to the surface of bone to monitor health and healing. The thin structure allows for accurate measurements over long periods, enabling personalized orthopedic care.
Researchers developed a novel model to identify specific genes and genetic alterations in multiple myeloma, stratifying the cancer's severity via DNA and RNA sequencing. This model revealed diverse subtypes and high-risk patients beyond current classifications.
Scientists at the University of Fukui developed a new triboelectric fabric that generates electricity from body movement, maintaining flexibility and breathability. The fabric, called AF-TENG, can power low-powered devices like LEDs and calculators, demonstrating its potential in wearable technology.