Articles tagged with Research and Development
Researchers from Xi'an Jiaotong-Liverpool University found that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke. The treatment increased cognitive and motor functions, and weighed more quickly than those treated with TMS alone.
A recent study published in Science Translational Medicine has found that supporting emotional connections between mothers and their premature infants can significantly improve brain development in these babies. The researchers measured the brain network functions of premature infants at term age after receiving either standard care or...
A cross-sectional study of 60 new therapeutic agents found no association between research and development investments and treatment costs. The study's findings suggest that drug companies should make further data available to justify high prices.
Researchers found no link between R&D costs and high drug prices in the US, contradicting industry claims. Despite $83 billion spent on R&D in 2019, drug prices are driven by market demand rather than investment costs.
Researchers at PNNL and UW discover a flow-based method to isolate pure magnesium salt from seawater, skipping energy-intensive purification steps. This approach could revolutionize US domestic magnesium production and enable more efficient processing of seawater.
Researchers analyzed changes in substance use disorder treatment admissions during the COVID-19 pandemic, revealing significant disparities by sex and ethnicity. The study highlights the need for tailored treatment approaches to address these inequities and ensure equitable access to care.
A new genomic test can predict a patient's risk of developing severe COVID-19, according to research from the University of Virginia Health System. The test, called CovGENE, analyzes genes expressed in a person's blood to determine if they may experience a severe disease course with increased risk of death.
Indiana University's Roger Innes leads a $1.2 million research grant project to create Fusarium Head Blight-resistant wheat and barley using genome editing techniques. The goal is to reduce dependence on environmentally damaging pesticides and increase crop yields.
A Korean research team created a dual-catalyst system that precisely controls catalytic reactions like cells. The nanoreactor combines magnetic materials and metal catalysts to selectively activate the catalyst under magnetic fields and near-infrared rays.
The conference highlights recent discoveries on polyphenol applications in microbiota, adipose tissue, nervous system, senolytic activity, ageing, and endothelial function. Over 131 communications will be presented during three days.
WaveLogix, a tech startup, has received a six-month SBIR Phase I grant from the National Science Foundation to develop its Internet of Things sensing system for infrastructure monitoring. The Rebel brand of concrete strength sensors directly measures real-time, in-place concrete strength without destructive testing.
A study by University of Cambridge and University of California, Berkeley finds that competition with China drove significant increases in clean energy investment between 2000 and 2018. The share of RD&D funding for clean technologies grew from 46% to 63%, while fossil fuel funding remained relatively unchanged.
Researchers at the University of Pittsburgh have identified a universal mechanism for lysosomal repair, known as the PITT pathway, which helps maintain cellular longevity. The study reveals that damaged lysosomes are quickly repaired through the PITT pathway, but defects in this process can contribute to age-related diseases such as Al...
A Cornell-led group of researchers has developed a search method that identifies terms similar to cancer screening tests in colloquial language, expanding conventional data-collection pipelines. The technique was applied to YouTube searches, retrieving relevant videos using words semantically close to the main term.
Scientists have developed a soft, bioresorbable device that cools peripheral nerves to reduce pain. The device was tested in rat models and found to be effective, reversible, and non-addictive, with potential applications for treating neuropathic pain after surgery.
Researchers at the University of British Columbia have made a breakthrough in developing an oral insulin tablet that is absorbed by the body in the same way as injected insulin. The tablet is designed to dissolve when placed between the gum and cheek, releasing all the insulin into the liver without wasting or decomposing it.
The proposed CODE-EHR best practice framework aims to standardize the use of structured electronic healthcare records in clinical research. The framework focuses on identifying and addressing data quality issues, ensuring interoperability between systems, and promoting transparency and trust.
Researchers from Singapore University of Technology and Design (SUTD) have developed a new Brain-Inspired Replay model that enables continual learning in edge computing systems without storing data. This approach achieves state-of-the-art accuracy and high energy efficiency, overcoming the stability-plasticity issue in traditional models.
A new project led by University of Illinois researchers aims to empower librarians with a toolkit for creating data-driven stories. The initiative, backed by an $99,330 grant, will provide easy-to-use templates for visualizing and structuring data narratives.
A team led by Jianxi Gao developed equations to measure and compare distances to tipping points across various mutualistic systems, allowing for the triage of declining ecosystems. This method enables the identification of areas that need intervention most urgently, providing a critical sense of urgency to mobilize resources.
A new risk score can help predict mortality for patients with atrial fibrillation who have undergone successful TAVR and been discharged home. The risk score was developed using data from the ENVISAGE-TAVI AF trial, which found that patients with certain clinical risks were more likely to die within a year of discharge.
The 7th International Meeting of the Digital Olfaction Society will take place in Tokyo, Japan, with a focus on digitalizing smells and aromas. The meeting aims to gather researchers, academics, and industry professionals to share knowledge and develop practical applications for olfactory digitization.
Researchers from Kyushu University analyzed global patent applications to identify R&D strategies for sustainable mining technologies. The study found that the Paris Agreement and raw metal price trends influence CCMT development, with varying degrees of impact by country.
Researchers developed a new quantitative RT-qPCR assay to detect and quantify the Omicron variant of SARS-CoV-2 in wastewater. The assay revealed that Omicron displaced Delta as the dominant variant within just 3 weeks in an Italian population.
The study reveals that environmental conditions cause RNA structures to change, affecting plant flowering times and potentially leading to more desirable traits. This technology can also be applied to human cells, enabling the design of RNA-based therapies for diseases like SARS-COV-2.
A new method to improve solid-state hydrogen fuel cell charging times has been developed by researchers from the University of Technology Sydney. The study used a semi-cylindrical coil heat exchanger, which significantly improved heat transfer performance and reduced charging time by 59%. This innovation has the potential to revolution...
MIT researchers developed a method to create 3D-printed materials with tunable mechanical properties and embedded sensors, enabling real-time feedback on movement and interaction. The sensing structures use air-filled channels that deform when moved or squeezed, providing accurate feedback for robotics and wearable devices.
Researchers at Aston University have developed a new approach to tackle one of the underlying causes of asthma, not just its symptoms. The treatment, which targets the structural changes made by asthmatic airways, shows promising results in mice, reducing symptoms within two weeks and returning airways to near normal.
Rose Faghih and her team have developed a novel inference engine to monitor brain activity in real-time using wearable devices, offering high scalability and accuracy. The algorithm can track mental states with high reliability, providing insights into autonomic nervous system activation.
Researchers developed a small molecule that effectively controls tumor growth by inhibiting PD-1/PD-L1 binding, overcoming accessibility and cost issues of existing antibody treatments. The new molecule has advantages in terms of affordability and oral administration, making immunotherapy more accessible to all cancer patients.
A new hydrogel-based platform increases vaccine thermal stability, enabling distribution in diverse regions without strict temperature control. The technology has the potential to reduce economic costs and health risks associated with cold chain logistics.
Researchers at TUM have developed a cell-free production method for bacteriophages, which can be used to target and combat specific types of antibiotic-resistant bacteria. The new technology has the potential to produce personalized therapeutic phages for clinical trials, addressing multi-resistant germ infections.
A new AI-based dynamic brain imaging technology has been introduced by Carnegie Mellon University, which can map out rapidly changing electrical activity in the brain with high precision and speed. The technology uses deep learning approaches to translate scalp EEG signals back to neural circuit activity without human intervention.
A newly developed polarizer-embedded metalens microscope system achieves high-quality, wide-field imaging with a large depth-of-field, significantly expanding human eyesight to the microworld. The chip-scale device offers a thousand-fold reduction in volume and weight compared to traditional microscopes.
A study of 17 African coastal countries found that those farther from the coast have lower standards of living, with fewer owning radios, TVs, and vehicles. Access to education and infrastructure are key factors in increasing prosperity near ports.
Researchers at Pohang University of Science & Technology developed a novel flash memory technology that increases data storage capacity and reliability through artificial defect generation. The new platform can distinguish eight data levels, making it suitable for neuromorphic computing and improving inference accuracy.
A Rutgers researcher contributed to a National Institutes of Health study confirming a link between phthalate exposure and increased risk of preterm birth. The study examined data from 6,045 pregnant women in the U.S., finding that higher concentrations of phthalate metabolites were associated with slightly higher odds of preterm birth.
A research team has won the NIH's Neuromod Prize for their innovative approach to spinal stimulation, which uses autonomic neuromodulation to regulate nervous system activity. The breakthrough could lead to improved autonomy and daily functioning for people with spinal cord injuries.
Researchers from Indiana University are developing a new biosensor that can analyze samples from 96 individuals in under three hours, with a sensitivity rate of 100% and specificity rate of 90%. The sensor detects not only the virus's spike protein but also the proteins created by the body to protect against the virus.
Researchers developed a new scale to capture heterogeneity among violent extremists, revealing distinct archetype dimensions such as 'adventurer' and 'drifter'. The tool has been validated across diverse groups, providing insights into personality traits and behavioral profiles of extremist individuals.
The International Vaccine Institute (IVI) has launched a two-week training course for biologics development and manufacturing, targeting low- and middle-income countries. The program aims to enhance local production of vaccines and biologics in LMICs to address vaccine inequity and global pandemic preparedness.
Researchers from Johannes Gutenberg University Mainz used AlphaFold to predict the structures of new protein knots, discovering the most complex knot and composite knots. These findings provide insight into folding mechanisms and evolutionary processes in proteins.
Researchers found that men who lose their Y chromosome as they age are more likely to experience deadly heart scarring and earlier death. The study suggests an existing drug may help counteract the effects of this loss, potentially leading to longer, healthier lives for affected men.
The NBSTRN 2022 Network Meeting showcased recent advancements in Newborn Screening (NBS) research, including Whole Genome Sequencing as Screening, Rare Disease advocacy, and Congenital CMV research. The meeting aimed to facilitate policy and research collaborations to improve NBS and rare disease outcomes.
The article discusses global disparities in Parkinson disease, identifying six key areas for improvement: disease burden, advocacy and awareness, prevention and risk reduction, diagnosis, treatment, and care, caregiver support, and research. These findings aim to inform policy decisions and drive action towards reducing health inequities.
Scientists developed a novel multilayer coating to improve the longevity of steel, increasing its lifespan by up to 400 hours. The coating, comprising three layers, was found to provide higher resistance to rust than conventional Zn coatings.
A UTSA professor will use a five-year $550,000 grant to study natural language processing and develop NLP models tailored to specific population groups. The goal is to improve the accuracy and relevance of these models in everyday applications.
Researchers developed a neural network algorithm that recognizes emotions and engagement from video images of faces, outperforming existing models in accuracy. The system can be integrated into video conferencing tools and online learning systems to analyze participant engagement and emotions.
Researchers at UNC School of Medicine discovered a protein complex that allows hepatitis A virus to replicate. They found that the oral compound RG7834 stops viral replication in an animal model, providing proof-of-principle for antiviral therapy.
Researchers at Saarland University are developing orthopaedic implants that can actively stimulate bone healing by undergoing controlled micromotions. These innovative implants, which use shape-memory wires, can provide real-time information on fracture progression and identify potential complications.
A team of researchers has successfully connected a partially paralyzed man's brain to a pair of robotic arms, allowing him to feed himself using subtle motor signals. The 'shared control strategy' enables the user to customize robot behavior with limited human input, creating a 'best of both worlds' environment.
The Biofinder instrument has successfully detected bio-residue in ancient fish fossils from the Green River formation, confirming that biological residues can survive millions of years. The device's capabilities make it an ideal tool for future NASA missions to detect signs of past life on other planetary bodies.
A novel liquid biopsy test can accurately detect cancer DNA in the blood of patients with metastatic breast cancer within five hours, potentially helping oncologists determine if treatments are working. The test's diagnostic accuracy is 85%, correctly detecting cancer 83% of the time and ruling out cancer 92% of the time.
A team of researchers from Kyushu University has developed an olfactory sensor capable of identifying individuals by analyzing the compounds in their breath. The system, combined with machine learning, achieved an average accuracy of over 97% in authenticating up to 20 individuals.
Researchers at Rensselaer Polytechnic Institute developed an accessible way to make N95 face masks that can kill viruses and bacteria on contact. The antiviral masks use a simple process with widely available tools, reducing plastic waste by allowing for longer wear.
Researchers developed an AI method to automatically detect plaque erosion in heart arteries using OCT images. The new technique uses neural networks and post-processing algorithms to predict regions of possible plaque erosion and refine the initial prediction based on clinically interpretable features.
Researchers use machine learning to automatically analyze Reflection High-Energy Electron Diffraction (RHEED) data, enabling faster and more efficient discovery of new materials. The study focused on surface superstructures in thin-film silicon surfaces and identified optimal synthesis conditions using non-negative matrix factorization.
Researchers have developed a unique 3D printed system to harvest mesenchymal stem cells from bioreactors, which can be used for various treatments. The system combines microfluidics and 3D printing to process adult stem cells, potentially making stem cell therapies more widely available.
A massive global study of social distancing motivations has yielded new insights into the effectiveness of different styles of messaging. Autonomy-supportive messages that encouraged personal agency were found to be more effective in influencing individuals' behaviors than controlling or shaming messages.
Researchers developed a rapid blood assay that measures the magnitude and duration of immunity to SARS-CoV-2, allowing large-scale monitoring of population immunity. The test takes less than 24 hours to perform and is scalable to use broadly in the population.