Articles tagged with Cancer Treatments
A new study published in The Lancet Haematology found that PET-CT is more accurate than conventional CT scanning in measuring response to treatment and predicting survival in patients with follicular lymphoma. The findings suggest that PET-CT should be used routinely in clinical practice to improve patient outcomes.
A new partnership between NSF, NCI, SU2C, and The V Foundation will explore transformative, theoretical biophysics for cancer research and treatment. This collaboration aims to merge life sciences with physical, computational, and engineering sciences to develop innovative approaches.
Researchers discovered that Axl and Mer receptors work in different settings to recognize and engulf dead cells. The study found multiple critical differences between the receptors, including their ligand use and regulation.
A population-based case-control study found no evidence that wearing a bra increases the risk of breast cancer among postmenopausal women. The study analyzed bra-wearing habits in relation to breast cancer risk using a rigorous epidemiological study design, providing reassurance to women about their bra-wearing habits.
A study conducted by National Cancer Centre Singapore found that breast cancer surgery can be safely performed on women aged 80 and above. Most patients recovered without complications, while only 3% developed major complications. The results dispel the misconception that surgery is unsafe for elderly patients.
Researchers found the avian H3N8 flu virus, which killed harbor seals, can spread through respiratory droplets and pose a threat to humans. Human immunity to the virus is lacking, raising concerns about possible person-to-person airborne spread.
Researchers at the University of Bristol have made a breakthrough in understanding how cells convert from attacking healthy tissue to protecting against disease. This discovery could lead to the development of a new treatment approach using antigen-specific immunotherapy, which may improve the lives of millions worldwide.
A Mayo Clinic study found that patients with poor quality of life before cancer surgery are nearly three times more likely to experience serious postoperative complications. Addressing these quality-of-life issues may reduce stress, speed recoveries and save healthcare costs.
The European Society of Cardiology publishes first recommendations on new oral anticoagulants for pulmonary embolism. The guidelines provide detailed recommendations on drug use and risk stratification, including age-adjusted D-dimer cut-offs.
A new integrated treatment programme is more effective at reducing depression and improving quality of life than current care for depressed cancer patients. The programme, called 'Depression Care for People with Cancer', includes both antidepressants and psychological therapy.
A meta-analysis of four studies found that photodynamic therapy (PDT) is more effective than cryotherapy in clearing actinic keratoses (AKs), a common skin lesion caused by sun damage. At three months after treatment, patients treated with PDT had a 14% better chance of complete lesion clearance compared to those who received cryotherapy.
Researchers developed a genomic-based system, IntClust, to classify breast cancer subtypes with high accuracy. The new system identified previously unnoticed subgroups of tumors, including those resistant to treatment, potentially leading to early detection and targeted therapies.
A UCLA study found that men with low prostate cancer knowledge experience increased decisional conflict and lower perceived effectiveness of treatment. Doctors can help by providing educational information before consultations to increase patients' comprehension and reduce regret.
Researchers at Hera Therapeutics have developed a therapy that blocks replication of high-risk HPV types, including HPV-16 and HPV-18, which cause 70% of cervical cancer. The company is developing a topical approach to treat HPV infection, offering hope to millions of women infected with these high-risk strains.
The NIH Follow that Cell Challenge seeks tools to monitor a cell's behavior and function over time, potentially leading to earlier diagnosis and improved therapies for diseases. The challenge aims to generate creative ideas and methods for following a single cell's behavior, using multiple integrated measures.
Researchers at the University of Edinburgh have validated a set of guidelines that identify girls with cancer most likely to enter early menopause. These criteria will help select patients for ovarian tissue freezing, potentially allowing young cancer survivors to have children in the future.
A study published in Cancer Epidemiology, Biomarkers & Prevention found that postmenopausal women who exercised at least four hours of walking per week had a 10% decreased risk of invasive breast cancer. The benefits of regular physical activity were rapid and short-lived, disappearing if exercise stopped.
Beaumont Health System receives a five-year National Cancer Institute Community Oncology Research Program grant to conduct cancer research and clinical trials in Michigan communities. The program aims to reduce cancer disparities and improve patient outcomes.
A study of postmenopausal women found no link between bisphosphonate treatment and reduced breast cancer risk. Researchers analyzed data from two randomized trials, concluding that bisphosphonates do not protect against breast cancer in this population.
A new analysis reveals that US lung cancer rates are declining overall, but also uncovering previously unrecognized trends related to different subtypes and demographic groups. The study found declining rates for squamous and small cell carcinoma, as well as unspecified lung cancer, among certain populations.
Researchers found mutations in the CTR9 gene in six children with Wilms tumour, a common kidney cancer in kids, and discovered that malfunctioning PAF1 complex is likely to cause cancer. The study's findings offer hope for improved treatments and screening for affected families.
Researchers at Cardiff University have identified a specific gene, Ligase 3, that human cells require to survive chromosomal defects and evade death. This discovery has significant implications for understanding the development of cancer and could lead to new therapeutic targets.
A study of nearly 3,000 cancer survivors found that nearly one in ten continued to smoke many years after diagnosis. The highest rates were seen among bladder and lung cancer patients. Meanwhile, sociodemographic factors such as age, education, and income played a role in smoking status.
The US Multi-Society Task Force on Colorectal Cancer recommends genetic testing of tumors for all newly diagnosed colorectal cancer patients with a familial risk of the disease. Genetic testing can confirm the diagnosis of Lynch syndrome and direct management for affected individuals, as well as family members.
A recent study published in the Journal of Clinical Oncology suggests that patient navigation can lead to better breast cancer care for high-risk populations, including minority women. Researchers found that patients assisted by trained navigators were more likely to start recommended treatments, such as hormonal therapy.
A new study suggests that consuming resistant starch alongside red meat can lower the risk of colorectal cancer. The study found that butyrated resistant starch reduced levels of certain genetic molecules associated with cell proliferation and increased risk of cancer.
A recent study has shown that a lung cancer diagnosis tool can be used safely in elderly patients, allowing doctors to make more accurate diagnoses and choose appropriate treatments. The tool, known as EBUS-TBNA, is effective for assessing whether a patient's tumour has spread to the lymph nodes.
The study found that skull-base heating can result in hazardous temperature elevations when sonications are performed close to the skull-base. Three new methods to counteract this phenomenon were developed. Additionally, the formation of standing-waves is greatly reduced with specifically designed large-area ultrasound transducers.
A large DNA analysis has identified several new genetic markers that signal increased risk of developing pancreatic cancer. The markers are variations in the inherited DNA code at particular locations along chromosomes.
Recent studies have shown that clustered DNA mutations are common in cancer development and may result from the process of DNA repair. The discovery provides a mechanism to potentially explain how genetic changes form in human cancers.
Researchers identified a genetic switch that stifles blood vessel development and used it to prevent peripheral vascular disease in a mouse model. The study's findings offer hope for new treatments targeting conditions like diabetes and atherosclerosis.
Researchers have identified a combination of pills that cures 9 out of 10 hepatitis C patients, achieving a 93% cure rate in 12 weeks. The treatment was well-tolerated by patients and offers a higher cure rate than previous standard care.
Researchers have discovered an innovative way to visualize where proteins touch each other using brightly hued dyes, a breakthrough that could lead to new treatments for various diseases. The technique involves mixing dyes with proteins and then separating them to reveal the 'hot spots' where proteins interlock.
The VOICES project at St. Jude Children's Research Hospital allows HIV-infected youth to anonymously share their stories, providing a powerful tool for clinicians and students to improve patient care. The project has empowered participants and given health care providers another layer of understanding into the emotional impact of HIV.
Patients with advanced cancer can experience improvement in fatigue, physical endurance, and mood through rehabilitation programs combining exercise and nutritional counselling. Palliative care services should incorporate these elements to enhance patient outcomes.
Researchers developed a powerful single-cell technique to study environmental effects on DNA, mapping epigenetic marks in individual cells. This approach has the potential to enhance clinical applications like cancer therapy and fertility treatments.
Researchers at The Feinstein Institute for Medical Research have identified a brain network that measures placebo effects in Parkinson's disease patients. This breakthrough discovery has the potential to improve the accuracy of clinical trials by excluding subjects who are more likely to experience placebo effects.
A new study by Henry Ford Health found that robot-assisted surgery can control prostate cancer for up to 10 years. The research followed 483 men who had not spread cancer beyond the prostate and received robot-assisted radical prostatectomy (RARP) as their first treatment, with 98.8% surviving the disease for 10 years.
A two-year study will examine the effects of cognitive behavioral and relaxation training on immune system functioning after surgery. Women who received these interventions reported reduced distress, improved mood, and enhanced emotional-well-being.
A new theory of cancer development proposes that recently evolved genes are damaged, leading to the use of older, inappropriate genetic pathways. This model could lead to innovative treatments by targeting the weaknesses in cancer cells' ability to proliferate rapidly.
Researchers developed a simple setup for X-ray phase-contrast imaging, which uses scrambled X-rays to produce high-quality images. The new technique demonstrates efficiency and versatility, enabling accurate measurement of specimen thickness and mapping of small structures.
A Baylor University study found that hypnotic relaxation therapy significantly reduced hot flashes in a 69-year-old man with prostate cancer. The treatment also improved his sleep quality, with a 94% decrease in hot flashes and an 87% improvement in sleep quality.
Researchers discovered that trace amounts of HCV RNA in successfully treated patients can be infectious. The study used an animal model to show that blood from these patients could cause HCV infection, which may be hard to detect due to delayed onset of disease.
Researchers from Case Western Reserve University report a high degree of satisfaction among caregivers who received support teams for terminal cancer patients. The intervention improved satisfaction in five areas: pain relief, managing pain, speed in treating symptoms, information about side effects, and coordination of care.
Rheumatoid arthritis is considered a syndrome rather than a single disease, and blocking inflammasomes may be an effective therapeutic target. Researchers have developed a mouse model that demonstrates the role of inflammasomes in RA and show promise for new treatments.
Researchers have identified a type I interferon marker that can predict patients with an increased risk of HCV relapse after antiviral therapy. Patients who maintain a strong type I interferon response are more likely to remain HCV-free.
Researchers at UT Southwestern Medical Center suggest that inhibiting the action of enzyme Cdk5 could substantially reduce brain damage after a stroke. The study found that aberrant Cdk5 activity causes nerve cell death during stroke and that blocking this enzyme can help preserve brain tissue.
Researchers have created a device using microchannel technology that can remove endotoxins from blood, preventing sepsis. The technology may offer an alternative to antibiotics and could be used as a prophylactic treatment.
A new microRNA has been identified as a potential therapeutic target for treating osteoporosis by blocking bone destruction. Researchers believe this discovery could lead to innovative treatments for conditions such as osteoporosis and other bone diseases.
A new research approach could improve medical study recruitment by adjusting treatment odds based on early results. In a recent study, patients shown an explanation of the odds were more willing to participate, with 67% volunteering compared to 54% without such explanation.
Activation of estrogen receptor β (ERβ) has been shown to limit tumor cell growth in breast cancer. In mouse models, cancer cells with activated ERβ did not grow well. Conversely, breast cancer patients with activated ERβ in their tissue had increased disease-free survival rates.
New mutations in cohesin proteins are common in various cancers, including bladder cancer and melanoma. Cohesin regulates cell division and DNA repair, making it a potential driver or facilitator for tumours.
Researchers have identified a new therapeutic target for certain myeloproliferative diseases by targeting the microenvironment that sustains hematopoietic stem cells. The treatment involves using clinically approved medications to prevent or reverse damage to this microenvironment.
Researchers at the University of Gothenburg have developed a new combination treatment for cancer using the molecules RVX2135 and HDAC inhibitors. The treatment has been shown to increase survival rates in mice with MYC-driven lymphoma by activating similar genes as existing cancer treatments.
A randomized trial found that telephone-based weight loss advice reduced breast cancer recurrence risk by lowering weight and inflammation. Postmenopausal women with breast cancer who received lifestyle coaching via phone achieved comparable sustained weight loss to in-person consultations.
Seven research projects funded to study genetic changes associated with autism spectrum disorders and improve diagnostics for hereditary cancers. Funding aims to advance understanding and treatment of these conditions, impacting families worldwide.
A team of researchers has found a potential way to enhance the body's ability to sense and inhibit viral infections by boosting a naturally occurring protein called OASL. This discovery could lead to more effective treatments for viruses ranging from hepatitis C to the flu.
A study found that childhood cancer survivors were hospitalized more often and for longer durations than the general population, with conditions like blood disorders and infections leading to hospitalizations. The study highlights the need for regular cancer-focused healthcare to identify health problems throughout their lives.
The study reveals that each glioblastoma tumor contains individual cells from multiple cancer sub-types, and that the distribution of these cells varies from tumor to tumor. This heterogeneity may contribute to drug resistance and disease recurrence, highlighting the need for personalized treatment approaches.
A study of over 2,600 adults with hepatitis B found that antiviral therapy significantly reduced the occurrence of liver cancer (HCC) by 60%. The therapy was more effective than treatment in preventing HCC than untreated patients. Results suggest a potential new approach to preventing a common and deadly form of cancer.