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Tuberculosis vaccine does not protect elderly against COVID-19

A large Dutch study found that the BCG vaccine does not protect elderly people with co-morbidities against COVID-19 symptoms. The study analyzed 6,112 participants and showed no difference in disease manifestations or hospitalizations between those who received the vaccine and those who received a placebo.

SourceUniversity Medical Center Utrecht·JournalClinical Microbiology and Infection·TypeRandomized controlled/clinical trial·DateFeb 2, 2023

Association of rurality with risk of heart failure

A study published in JAMA Cardiology found that rurality is associated with a higher risk of heart failure among predominantly low-income individuals in the southeastern United States. The inequity highlights the need for targeted primary prevention efforts for rural populations.

SourceJAMA Network·JournalJAMA Cardiology·DateJan 25, 2023

More steps, moderate physical activity cuts dementia, cognitive impairment risk

A new study led by the University of California San Diego found that daily walking and moderate-to-vigorous physical activity significantly reduced the risk of developing mild cognitive impairment or dementia in senior women. With each additional 1,865 steps per day, the risk was lowered by 33%, while moderate-to-vigorous physical acti...

SourceUniversity of California - San Diego·JournalAlzheimer s & Dementia·TypeObservational study·DateJan 25, 2023

Body phenotypes say a lot, but not everything, about a person’s health, according to new Concordia research

Concordia researchers analyzed muscle and fat mass data from a large US sample population to find that high levels of fat mass are linked to poorer overall health. While BMI was surprisingly effective in predicting some cardiometabolic outcomes, the study suggests new body-composition phenotypes may be a better predictor.

SourceConcordia University·JournalPreventive Medicine·TypeData/statistical analysis·DateJan 25, 2023

Study shows how cells prevent harmful extra DNA copies

Researchers at Weill Cornell Medicine have identified a crucial mechanism that prevents cells from replicating extra DNA, reducing the risk of cancer and genome instability. The study reveals that a licensing protein called CDT1 acts as a brake on DNA replication, preventing it from progressing once licensed sites are established.

SourceWeill Cornell Medicine·JournalMolecular Cell·DateJan 24, 2023

Dartmouth-led study finds that team-based coaching reduces risks of acute kidney injury after heart procedures

A Dartmouth-led study found that team-based coaching significantly improves the risk of acquiring post-procedural acute kidney injury (AKI) when compared to other interventions. The Collaborative with Surveillance intervention reduced the odds of AKI by 46 percent, making it a promising approach to address this prevalent adverse event.

SourceThe Geisel School of Medicine at Dartmouth·JournalClinical Journal of the American Society of Nephrology·TypeRandomized controlled/clinical trial·DateJan 19, 2023

Benefits of oral hygiene can drive university students towards dental check-ups

A study by researchers from Okayama University found that Japanese university students' willingness to undergo regular dental check-ups is associated with their thoughts regarding the health-belief model and oral health behaviors. The study suggests that the perceived benefit of undergoing regular check-ups drives young students toward...

SourceOkayama University·JournalInternational Journal of Environmental Research and Public Health·TypeSurvey·DateJan 16, 2023

Fall rate nearly 50% among older Americans with dementia

A new study reveals that falls are nearly 50% among older Americans with dementia, emphasizing the importance of addressing environmental and health-related risk factors. Key findings highlight the need for tailored screening and prevention interventions specifically designed for this high-risk population.

SourceDrexel University·JournalAlzheimer s & Dementia·DateJan 12, 2023

Scientists improve the equation in FDA guidance predicting drug interactions

Researchers have improved the FDA's equation for predicting drug interactions by addressing fundamental limitations and incorporating new models. The modified equation has shown a significantly increased accuracy of about 80%, which is expected to contribute to increasing the success rate of new drug development.

SourceInstitute for Basic Science·JournalClinical Pharmacology & Therapeutics·TypeComputational simulation/modeling·DateJan 12, 2023

Military service members who hide their suicidal thoughts are more likely to store their firearms unsafely

A Rutgers study found that military service members who hide their suicidal thoughts and avoid behavioral health care tend to store their firearms unsafely. Those with undisclosed past year suicidal thoughts stored their firearms at home more often and with a locking device in place less often.

SourceRutgers University·JournalSuicide and Life-Threatening Behavior·TypeSurvey·DateJan 9, 2023

Physical fitness a demographic watershed

A study of 5,308 participants aged 50-64 found significant correlations between sedentary behavior and low fitness levels. Highly uneven fitness distribution was observed among groups at higher risk, including older adults, foreign-born individuals, and those with poor health and lifestyle habits.

SourceUniversity of Gothenburg·JournalBMJ Open·DateDec 22, 2022

Where do reproductive-age women receive preventive health care?

A UMass Amherst study reveals that 61% of wellness visits for reproductive-age women (15-49) were with OB-GYNs, while chronic condition patients also relied heavily on these specialists. Key preventive services like pap tests and pelvic exams were more common in OB-GYN settings, whereas lipid testing was rare.

SourceUniversity of Massachusetts Amherst·JournalHealth Services Research·TypeData/statistical analysis·DateDec 22, 2022

Hispanic and Latino young males with higher education, greater acculturation are more likely to use e-cigarettes

A Rutgers study found that Hispanic and Latino young men with higher education who were born in the US and speak mostly English at home are more likely to use e-cigarettes. The study analyzed data from 11,275 adult participants and found a high use of e-cigarettes among those under 45 years of age.

SourceRutgers University·JournalAmerican Journal of Medicine Open·TypeData/statistical analysis·DateDec 20, 2022

This hormone may be the missing ingredient to heart-healthy cholesterol levels for menopausal women

A new study identifies anti-Müllerian hormone (AMH) as a key factor in regulating cholesterol levels during the menopause transition. High AMH levels are associated with lower HDL-C, or good cholesterol, which may indicate cardiovascular risk despite its traditionally protective effects.

SourceUniversity of Pittsburgh·JournalJournal of Clinical Lipidology·TypeObservational study·DateDec 12, 2022

New antimalarial drug requires higher doses to cure infection

A new antimalarial drug, tafenoquine, is found to require a higher dose of 450mg to achieve cure rates of 85% compared to the current 300mg dose of 70%. The study suggests that the single-dose tafenoquine is not as effective as optimal primaquine treatment in preventing vivax malaria relapses in all endemic regions.

SourceeLife·JournaleLife·DateDec 6, 2022

As family dynamics evolve, WVU study reveals health care limitations for children not raised by two parents

A WVU study found that children from non-traditional family structures, such as single-parent households and multi-generational families, face difficulties accessing healthcare. The research highlights the need for providers to be aware of the unique challenges faced by these families and to adapt their services accordingly.

SourceWest Virginia University·JournalJournal of Family Nursing·DateDec 6, 2022

Self-driven healthcare can improve health outcomes and reduce costs

A self-driven healthcare ecosystem supports individuals in managing their own health and wellbeing by recording and uploading data through a secure online portal. This approach aims to improve health outcomes while controlling costs and addressing social determinants of health.

SourceSAGE·JournalJournal of the Royal Society of Medicine·DateDec 1, 2022

Clover’s vaccine candidate reduced household transmission of SARS-CoV-2 in study published in Clinical Infectious Diseases

A global Phase 2/3 clinical trial found that vaccination with SCB-2019 reduced the risk of transmitting SARS-CoV-2 infection to household members. The study showed a significant reduction in symptomatic cases among vaccinated household contacts and indicated that vaccines can play an important role in controlling future outbreaks.

SourceInternational Vaccine Institute·JournalClinical Infectious Diseases·TypeRandomized controlled/clinical trial·DateNov 30, 2022

Reduced use of child sexual abuse material after online CBT

Researchers at Karolinska Institutet found that internet-delivered anonymous cognitive behavioural therapy (CBT) significantly reduced the viewing of child sexual abuse material. The study, published in Internet Interventions, shows promise for a feasible and effective treatment approach.

SourceKarolinska Institutet·JournalInternet Interventions·TypeRandomized controlled/clinical trial·DateNov 30, 2022

A new therapeutic target for the prevention of heart failure due to aortic stenosis

A new gene therapy approach has been developed to boost the expression of the beta-3 adrenergic receptor in heart cells, improving mitochondrial function and preventing or reversing heart failure in a mouse model of aortic stenosis. This could potentially provide new therapeutic options for patients with this condition.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalBasic Research in Cardiology·TypeExperimental study·DateNov 30, 2022

Researchers explore why patients don’t follow up with their doctors after receiving a positive colorectal cancer test

A nationwide questionnaire in Dutch colorectal cancer screening found that concerns about colonoscopy, lack of provider discussion, and personal risk perceptions are common reasons for not following up. Personalized screening counseling and family practitioner involvement may help increase follow-up rates.

SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 29, 2022

People with depression are less likely to have children

Research suggests that people with depression are less likely to have children, particularly men. The study, which examined over 1.4 million participants in Finland, found a significant association between diagnosed depression and the likelihood of having children, as well as the number of children born.

SourceUniversity of Helsinki·JournalAmerican Journal of Obstetrics and Gynecology·DateNov 28, 2022