A study of nearly 67,200 postmenopausal women found that the Fracture Risk Assessment Tool (FRAX) was inadequate for identifying osteoporotic fracture risk across racial/ethnic categories. However, the Osteoporosis Self-Assessment Tool (OST) was excellent for detecting osteoporosis within each category.
A decision analytical model found that increased uptake of bivalent booster vaccination among eligible age groups decreased pediatric hospitalizations and school absenteeism. The benefits of booster campaigns for children may be substantial, suggesting a focus on younger populations is crucial.
Dr. John H. Bushweller's team at UVA Cancer Center is developing novel drugs to block abnormal proteins that cause pediatric leukemia. The new approach aims to improve efficacy and reduce toxicity, potentially leading to better patient outcomes.
A recent French study reveals lesbian and bisexual women have worse cardiovascular health scores than heterosexual women, while gay and bisexual men tend to have better scores. Rural-residing sexual minority men also experience poorer cardiovascular health compared to heterosexual men.
A nationwide analysis of prisoner healthcare incidents in England reveals medication-related harm as a major issue, with staff mistakes being the most common cause. The researchers recommend prioritizing timely access to healthcare services, improving processes to mitigate medication-related harm and increasing remote appointments.
Researchers developed a new tool to predict heart disease risk in those over 40 based on their total exposure to heart disease risk factors. The study found that black patients have a 46% greater risk of developing heart disease compared to white patients.
Researchers identified novel genetic associations between AD and modifiable risk factors, including high HDL cholesterol concentrations and systolic blood pressure. These findings may inspire new drug targets and improved prevention strategies for AD.
Athletes from less affluent countries face significant barriers in preventing injuries due to lack of health education and medical expertise. A new study reveals stark inequalities in support resources between international competitors.
Researchers have developed a new instrument to thoroughly characterize the optical properties of specialized eyeglass lenses used to slow myopia progression. The study's findings provide valuable information on how these lenses interact with eye elongation and shed light on their effectiveness in real-world scenarios.
Physicians are urging primary care teams to use data-driven approaches to prevent and mitigate climate-related health issues, dubbed "precision ecologic medicine". This approach combines patient-specific data with climate-related information to predict and support vulnerable patients.
A new interactive online Fragility Fracture Decision Aid can help clinicians and patients visualize their individual risk of fracture. The Canadian Task Force on Preventive Health Care recommends a "risk assessment–first" screening process for women 65 years and older, centered around shared decision-making with primary care providers.
A specialized weight loss program for Deaf people, designed and led by Deaf individuals, resulted in significant weight loss among participants. The Deaf Weight Wise program focused on lifestyle changes, social support, and cultural relevance, leading to a higher retention rate and better outcomes compared to mainstream programs.
A study of 1,340 women with high-risk breast cancer found that strongest collective adherence to lifestyle recommendations was associated with significant reductions in disease recurrence and mortality. Education strategies to help patients adhere to cancer prevention recommendations are warranted.
Researchers at UVA Health System have made a breakthrough discovery about the role of microglia in seizure disorders. The study suggests that enhancing microglial activity could be a promising approach to preventing and managing seizures, offering new hope for patients who don't respond to existing treatments.
The latest May issues of American Psychiatric Association journals focus on new treatments for conditions like trichotillomania, social anxiety disorder, and opioid use disorder. Additionally, a special issue of Focus journal explores suicide preventive interventions and knowledge.
The USPSTF recommends screening for latent tuberculosis infection (LTBI) in populations at increased risk, including those born in or former residents of high-prevalence countries and congregate settings. Estimated prevalence is about 5.0% in the US, with up to 13 million persons affected.
A large study found no difference in cardiovascular outcomes between patients taking beta blockers and those who didn't, after a year of hospital discharge. The researchers suggest reevaluating the value of long-term beta blocker therapy in low-risk heart attack patients with normal functioning hearts.
More than half of stroke survivors develop cognitive impairment within a year, with 1 in 3 at risk for dementia. Early screening and comprehensive care are advised to support stroke survivors with cognitive impairment.
Strokes can be largely prevented through education and lifestyle changes, such as moving more, healthy eating, and managing blood pressure. The American Stroke Association is launching a digital tool to educate people on stroke warning signs and risk factors, particularly for diverse populations.
Research from Edith Cowan University found that lower grip strength and slower timed-up-and-go tests were significant risk factors for presenting with dementia. The study suggests that incorporating muscle function tests into dementia screening could help identify high-risk individuals who may benefit from primary prevention programs.
A randomized clinical trial found that community health workers in early childhood well-child care teams improved receipt of preventive care services compared to usual care. The intervention resulted in better outcomes for Medicaid-insured children, highlighting the potential benefits of team-based approaches to healthcare.
A comprehensive care plan has been published to prevent preeclampsia, a leading cause of pregnancy-related death in the US. The plan provides specific recommendations for both expecting parents and clinicians, including daily low-dose aspirin, surveillance, and behavioral strategies.
SourceMirvie·JournalAmerican Journal of Obstetrics and Gynecology·TypeLiterature review·DateApr 28, 2023
A new study found six suicide clusters, four overdose clusters and nine alcohol-related liver disease clusters in the US west, southeast and Appalachia/rust belt. These co-occurring clusters suggest specific regions at increased risk for deaths of despair warranting public health intervention.
SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateApr 26, 2023
Researchers found that CUDC-907 selectively induces apoptosis in cells driven to senesce by p53 expression. The compound showed senolytic properties in different models of stress-induced senescence, depending on its inhibitory effects on HDACs and PI3K.
A new study finds that buprenorphine initiation rates and six-month retention rates remain flat despite policy changes aimed at increasing access to the medication. Only 22% of patients who started treatment kept refilling their prescriptions for at least six months, highlighting barriers to prescribing enough of the life-saving drug.
A new study finds that an estimated 6.5 million Californians are concerned about a friend or family member who may harm themselves or others due to substance misuse, history of violence, or firearm access. The survey shows that 85% of respondents who knew someone at risk took actions to reduce the risk, but few addressed firearm access.
Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.
Researchers developed a machine learning model that predicts strokes more accurately than current systems, using data available at hospital arrival. The model achieved high precision and sensitivity, outperforming existing scales.
A new study found that quality of heart failure care is equitable for 11 of 14 evidence-based clinical care measures, with no disparities in care between Black and white patients. However, the study highlights areas for improvement, including gaps in care quality and social determinants of health.
The 18th Key Symposium on Healthy Ageing and Longevity takes place in Okinawa, bringing together world experts to discuss the latest research on blue zones. The symposium aims to promote both longevity and healthy ageing to reduce age-related diseases and healthcare burden.
A global study published in Cochrane Reviews found that consuming cranberry products reduces the risk of repeat symptomatic UTIs in women by more than a quarter. The review also showed benefits for children and people susceptible to UTIs following medical interventions, with minimal side effects reported.
A study found that practicing music and active listening can alter cognitive decline in healthy seniors by promoting brain plasticity. The researchers discovered an increase in grey matter volume in four brain regions involved in high-level cognitive functioning.
A study by an international research team has found a mechanism that occurs in brown bears and paraplegics, preventing the formation of blood clots. The discovery could lead to new treatments for venous thromboembolism, a life-threatening condition.
A study published in Brain found that disconnecting nerve pathways in the brain can lead to improved seizure freedom in patients with frontal lobe epilepsy. The research, involving 47 patients, revealed that cutting these connections resulted in 88% of patients being seizure-free after three years.
A team of researchers at Aarhus University has discovered a protein that helps protect the body against blood clots in hibernating bears. The protein, HSP47, is found to be downregulated during winter months, allowing bears to avoid blood clots.
A new study published in the American Journal of Preventive Medicine found that reducing added sugars consumption by an average of 14 to 57 calories per day is sufficient to meet the Healthy People 2030 target. This represents just less than half of a 12-ounce soft drink, and requires minimal changes to dietary habits.
SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateApr 13, 2023
A study of over 5 million hospitalizations found COVID-19 patients were more susceptible to HAIs, requiring additional prevention measures. Despite increased infection control pressures, HAI rates among inpatients without COVID-19 remained similar to those in 2019.
Despite the decline in most services, FQHCs reported an increase in patient visits for substance use disorder, depression, anxiety, and sexually transmitted infections. Quality-of-care measures also plummeted, with only one measure returning to pre-pandemic levels.
A randomized trial found tailored education and peer support significantly reduced binge-drinking among Army National Guard members over the course of a year. Participants who received online education sessions and supportive phone calls from veteran peers showed substantial declines in binge-drinking days and scores on risk assessments.
A nationwide study found that more experienced resident physicians are at risk of medical errors when working extended-duration shifts or long weekly hours, similar to first-year residents. The study calls for policy changes to limit work hours and extend safer training periods in the US.
A recent study published in the New England Journal of Medicine found that tranexamic acid did not reduce the need for blood transfusions or prevent maternal death in patients with increased risk for excessive bleeding after cesarean delivery. However, patients who received tranexamic acid had less need for additional medical intervent...
Researchers found that alcohol screening rates significantly declined during the initial COVID-19 surge due to competing pandemic priorities and telemedicine shifts. Screening rates later recovered as in-person care resumed and telemedicine workflows improved.
Researchers found that timed birth strategies, including induced labor and Cesarean deliveries, can reduce the risk of at-term preeclampsia by more than half. The study analyzed over 90,000 pregnancies and suggested that this approach has huge potential for global good in maternity care.
Researchers found clinician-owned practices significantly improved quality of cardiovascular preventive care without burnout among clinicians and staff. Across various practice sizes, geography, and composition, 18.3% met criteria for quality and well-being promoting practices.
Using image-based computational blood dynamics, researchers mimicked health conditions and investigated hemodynamic parameters to better understand how aneurysm size affects blood flow. They found that altered blood flow velocity distribution can lead to rupture, emphasizing the importance of early detection and treatment options.
Studies investigate multimorbidity, which is increasing due to improved survival from chronic diseases and population aging. The prevalence of multimorbidity varies greatly depending on the number and types of conditions considered, with some combinations spending more than the sum of individual diseases.
A randomized clinical trial found that a video-based decision support tool increased patient knowledge, but not assent, to ICD implantation among Black patients. The study also highlighted the complexity of aversion to cardiac procedures in Black communities, emphasizing the need for further research on social determinants of health.
A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...
A major international study published in Nature Genetics has provided new insights into the genetics of preterm birth and pregnancy length. The research reveals a mutually antagonistic effect between the woman's and unborn child's genes, favoring earlier labor for the mother's survival and extending pregnancy for the child's weight gain.
Researchers found that metformin + leucine (MET+LEU) treatment prevents myotube atrophy by reversing cellular senescence and improving proteostasis. The study used C2C12 myoblasts, aged mouse single myofibers, and human primary myotubes to demonstrate MET+LEU's skeletal muscle cell-autonomous properties.
A recent study suggests that cardiac sphericity, or the roundness of the heart, may be a useful indicator for diagnosing cardiovascular conditions. The research used machine learning to analyze medical images and found a link between increased sphericity and future heart troubles.
A UCF research team, in partnership with the City of Orlando, aims to prevent falls among older adults through a low-cost, portable technology-based intervention. The project seeks to address public health disparities and support the development of affordable housing options.
A study of 32 Black patients with type 2 diabetes found that humanistic communication, family involvement, and clear medical information are crucial for effective shared decision making. The research team offers recommendations to improve SDM in safety-net primary care settings.
Researchers investigated perspectives of Black patients on shared decision making (SDM) during medical appointments. They identified preferences for humanistic communication, the need for doctors to account for family members' roles in decision-making, and a growing mistrust in doctors. The study's findings offer insights for adapting ...
A recent study found that social determinants of health influenced care in 35% of surveyed encounters, with the most common sources being patient conversations and prior knowledge. Integrating this data into EHRs can support personalized care planning.
Researchers have developed a novel technology for nanoencapsulation of bioactive compounds, specifically anthocyanin, using pectin and lysozyme. The methodology ensures slow release of the compound, allowing it to survive gut bacteria and digestive enzymes.
Rates of naloxone prescriptions for high-risk individuals and co-prescribing with opioids rose in emergency departments from 2012 to 2019. Opioid prescribing guidelines made it easier for doctors to prescribe naloxone, which is highly effective at reversing opioid overdose effects.
The US Preventive Services Task Force (USPSTF) is updating its methods to prioritize topics based on disease burden, extent of new evidence, and ability to be provided in primary care. The task force will increasingly consider health equity when making recommendations.
Research highlights that intensive behavioral weight loss programs significantly reduce cardiovascular disease and Type 2 diabetes risk factors, which persist for at least five years. Participants who lost weight through such programs had lower risk factors compared to those in less intensive or no weight loss programs.
A new research letter highlights how quickly Colorado's children and teenagers can access a loaded gun, increasing the risk of adolescent suicides and firearm injuries. Nearly one-third of middle and high school students report having access to a gun within 24 hours or under 10 minutes.