Articles tagged with Asthma
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study of 2,000 children suggests that London's diesel-dominated air pollution is restricting lung capacity, putting them at risk of lifelong breathing disorders. Despite improvements in air quality through the introduction of Low Emission Zones, there was no evidence of a reduction in small lungs or asthma symptoms.
A clinical trial found that eating fish twice a week as part of a Mediterranean diet can significantly decrease lung inflammation in children with mild asthma. The study involved 64 children from Greece and showed improved lung function after six months.
A study published in Environmental Health Perspectives found that air pollution from ozone and fine particulate matter may be responsible for nine to 33 million emergency room visits globally. The research suggests that policies aimed at cleaning up the air can reduce the global burden of asthma.
A study using single-cell transcriptomics reveals the cellular and functional changes underlying type 2-high asthma, which can lead to more severe disease. The research provides new insights into how airway epithelial cells produce mucus and could inform the development of targeted treatments for asthma and other airway diseases.
A new study published in Pediatric Research found that children with asthma growing up in polluted NYC neighborhoods need emergency medical treatment more often. The study suggests that these areas may have other environmental factors affecting urgent asthma treatment.
A USC-led study of over 20,000 European youths found that children with asthma are more likely to become obese. Asthma increases the risk of obesity by 50-66%, especially in those with persistent wheezing symptoms.
Researchers at UCalgary's Alberta Children's Hospital Research Institute and Hotchkiss Brain Institute discovered the nervous system plays a critical role in asthma attacks. By targeting treatment at the carotid bodies, they found that blocking receptors during an asthma attack can eliminate symptoms.
Researchers analyzed children's asthma management and found that environmental exposures like secondhand smoke and pet ownership were not significant factors in improving asthma control. Once asthma guidelines are followed, these exposures do not impact overall asthma improvement.
A University of Utah engineering study shows that smart controllers for home heating and cooling systems can clean pollution with minimal additional energy costs. The 'SmartAir' setting, which turns on the HVAC fan based on both temperature and air quality, cleaned the air almost as well as continuous operation but used 58% less energy.
A non-pathogenic fungus can expand in the intestines of antibiotic-treated mice and enhance the severity of allergic airways disease. The study suggests that alterations in gut microbiota induced by intestinal fungi might be a previously unrecognized but potentially important risk factor for patients with asthma.
A study published in Respirology found ten treatable traits predictive of future asthma attacks, including depression and vocal cord dysfunction. The findings may help clinicians tailor treatment plans for patients with severe asthma.
Research suggests that weight gain between childhood and puberty increases the risk of developing asthma later in life, including for future generations. The study found no correlation between weight gain before or after puberty, but rather a link to overall inflammation during this critical developmental period.
A new study found that children who have access to green spaces near their homes are less likely to experience respiratory problems as adults. The research, conducted by RHINESSA, analyzed data from over 5,400 participants and found a significant association between exposure to greenness and reduced respiratory symptoms.
A study found that paracetamol use in infancy may increase the risk of asthma in adolescents, particularly those with certain genetic variations of the glutathione S-transferase (GST) genes. Children who took paracetamol more frequently had a higher risk of developing asthma, especially if they carried the GSTP1 Ile/Ile variant.
Researchers found high immunoglobulin E (IgE) levels among babies born in October and December in Melbourne, indicating a potential link between maternal exposure to grass pollen and increased risk of respiratory diseases. Conversely, being pregnant for an entire grass pollen season may have a protective effect on babies.
Children with childhood asthma are at a disadvantage in education, leaving them more likely to drop out of university and struggle to enter non-manual occupations.
A new study has found that people with asthma are more likely to become obese, especially if their asthma begins in adulthood or if they have non-allergic asthma. The research, which followed over 8,600 participants for two decades, suggests the relationship between asthma and obesity is more complex than previously thought.
Researchers found that inhaled steroid use is associated with a higher risk of developing nontuberculous mycobacteria lung infections. The study analyzed medical records of patients diagnosed with NTM lung infections and found that the odds of infection were 2.7 times greater in those who used inhaled steroids.
Researchers have discovered a marker that can help identify patients with severe asthma who are likely to respond well to new treatments. The marker targets inflammatory cells called eosinophils, which play a key role in the condition.
Researchers at OHSU used 3D imaging to investigate airway nerves in asthma. They found that denser nerves are associated with more severe symptoms and increased eosinophils. This new insight could lead to better treatments for asthma.
Asthma patients with specific genetic profiles exhibit more intense symptoms following traffic pollution exposure. The study suggests that tailoring treatments to individual gene-environment interactions could enhance quality of life for people with asthma.
A new study found that early childhood weight gain velocity and body mass index are associated with lower lung function at age 10. Children who reached peak body mass index later had better lung function and a lower risk of asthma.
A study found that nearly 40% of women with asthma may develop COPD, but certain factors such as smoking, obesity, and socioeconomic status may lower this risk. The researchers identified individual risk factors playing a more significant role in the development of COPD overlap syndrome than exposure to air pollution.
A Johns Hopkins study found that fewer than half of Baltimore caregivers for preschool children with asthma can manage their child's chronic condition. The researchers evaluated caregiver preparedness through medication availability, identification, and dosing instructions.
A new study by Brigham and Women's Hospital researchers models allergic lung inflammation in mice, revealing the role of neutrophil extracellular traps (NETs) in triggering and amplifying an allergen-initiated immune response. The findings have implications for designing more precise clinical trials for severe asthma treatment.
A small pilot clinical trial shows eating two CHORI-Bars daily for eight weeks improves lung function in obese adolescents with asthma. The study's findings are provocative and suggest a need for larger trials.
A new study found that eczema is associated with a worse quality of life than several other chronic illnesses. Moderate and severe eczema were particularly burdensome, causing symptoms like blisters, pain, and sleep disturbance.
Adults with uncontrolled asthma have a moderately increased risk of developing atrial fibrillation, an irregular heart rhythm. Researchers are unsure of the underlying causes for this association and urge further investigation.
A new study published in the European Respiratory Journal found that healthy diets with high consumption of fruits, vegetables, and whole grain cereals are characterised by better asthma outcomes. Men who ate healthier diets had a 30% lower chance of experiencing asthma symptoms.
A £2 million project aims to improve asthma control in African schoolchildren, with a focus on 3,000 children aged 12-14. The study will use theatre performances to address asthma knowledge and stigma, and assess the barriers to achieving good control.
A review of 16 studies reveals a strong association between fast food intake and an increased risk of asthma, wheeze, and other allergic diseases. Hamburger consumption was found to be most prominently associated with these conditions in a dose-dependent manner, regardless of income level.
A study of nearly 50,000 New Zealand children found that greener neighborhoods are less likely to develop asthma, while low plant diversity is associated with a higher risk. Biodiversity conservation may provide concrete health benefits beyond its ecological significance.
Researchers develop novel small molecule, PM-43I, that specifically targets STAT6 pathway, reversing preexisting allergic airway disease in mice. This breakthrough approach offers unique advantages over monoclonal antibodies, with potential benefits for patients who may not need steroid treatments.
A new diagnostic test that uses a simple nasal brush to identify mild to moderate asthma has been developed by Mount Sinai researchers. The test, which uses machine learning algorithms and RNA sequencing, can differentiate asthma from other respiratory conditions and is less expensive than traditional pulmonary function testing.
A new study suggests that vaccinating asthmatic children against the flu could significantly reduce their risk of needing hospitalization for an asthma attack. The study found that kids with influenza or parainfluenza had a 37-per-cent or more chance of not responding to treatment, compared to 13 per cent for children without a virus.
Researchers from the University of Pennsylvania School of Medicine have identified the source of IL-25, an inflammatory cytokine linked to chronic rhinosinusitis and asthma. The study found that solitary chemosensory cells in the sinuses produce IL-25, which can recruit immune cells and lead to inflammation.
Asthma management is complicated by heterogeneity and variability, making it difficult to implement optimal strategies. The role of physicians in managing asthma complexity is particularly challenging, requiring knowledge, dedication, and experience.
A study found that patients hospitalized for asthma who received antibiotics had longer hospital stays and higher costs, but no reduced risk of treatment failure. Antibiotic-related diarrhea was also more common in treated patients.
Researchers found a new treatment, dupilumab, effective in treating severe asthma by blocking key drivers of inflammation. The study showed improved asthma symptoms, lung function, and reduced need for corticosteroids.
Dupilumab alleviates asthma symptoms and improves lung function in moderate to severe asthma patients. The drug significantly reduced asthma exacerbations by half in some patients, with improved rates of emergency room visits and hospitalizations.
A long-term study has found that exposure to ozone at birth is associated with an increased risk of developing asthma, allergic rhinitis, and eczema in childhood. The study, which followed 1,881 children from birth to age 17, found that even small increases in ozone exposure were linked to a higher risk of developing these conditions.
Researchers have found a patient-centric treatment that works for people with mild asthma, using an as-needed combined-drug inhaler. The study, led by Paul O'Byrne, showed the inhaler was superior to conventional treatment strategies in reducing asthma attacks and improving symptom control.
A high-fiber diet increases survival in influenza-infected mice by setting the immune system at a healthy level of responsiveness. It also boosts antiviral immunity by activating T cells, mediated by changes in gut bacteria composition.
A recent study published in Pediatrics found that no single category of intervention was effective in reducing hospital readmission for children with asthma. However, multimodal interventions that combined multiple categories showed promise in reducing the risk of readmission between 30 days and one year after initial discharge.
A study found that asthma mortality rates are falling among younger people in the poorest areas compared to the wealthiest, but remain higher in older adults. Regional variations persist, with significant differences in outcomes across England.
A recent study published in the Journal of Allergy and Clinical Immunology found that children living close to major roadways had nearly three times the odds of pediatric asthma compared to those who lived farther away. The researchers also discovered a stronger link between lifetime pollution and asthma among school-age girls.
A new study published in Frontiers in Psychiatry found a significant link between common allergic diseases and a broad spectrum of psychiatric disorders. Patients with asthma and hay fever were found to have a 1.66-fold increased risk of developing a psychiatric disorder within a 15-year period.
Researchers found variations in immune cells in children from higher vs lower socioeconomic status families. This disparity affects asthma control and suggests a link between socioeconomic factors and immune system dysfunction.
Researchers found that children with asthma often miss their daily medication due to barriers such as forgetfulness and running out of medication. The study suggests that improving communication among patients, families, and pediatric clinicians is crucial to ensure consistent use of daily anti-inflammatory medication.
A new study published in the European Respiratory Journal found that long-term exposure to high levels of road traffic and ozone significantly increases the risk of asthma symptoms and medication use. The study also identified a biological marker, 8-isoprostane, which is exhaled in the breath and linked to tissue damage in the lungs.
A new lung MRI method helps identify where airway inflammation and smooth muscle dysfunction occur in patients with severe asthma. This innovation aims to personalize therapy for individual patients, improving disease control and quality of life.
A new study suggests that air pollution from traffic-related emissions is a significant contributor to childhood asthma cases in Bradford, with up to 24% of annual cases potentially attributed to this factor. The research highlights the need for policies aimed at reducing traffic-related air pollution to mitigate its effects on childre...
Having measles in early childhood may predispose individuals to asthma-like symptoms and airway obstruction if they also smoked. Adults with a significant history of asthma and smoking are at a higher risk of developing chronic obstructive pulmonary disease.
A clinical trial found that increasing inhaled steroids at the first signs of an asthma attack does not prevent attacks in children with mild to moderate asthma. Children in the high-dose group experienced slower growth rates compared to those on low-dose medication.
Researchers found that using a single corticosteroid and long-acting bronchodilator treatment for both daily asthma control and rescue relief is more effective than separate medications. This approach significantly reduces asthma attacks, hospitalizations, and emergency room visits.
A team of scientists has identified a human protein called interleukin-33 (IL-33) that reacts to various environmental allergens, including mold, pollen, and cockroaches. This discovery establishes a direct link between genetics and the environment, and offers new potential targets for treatment of allergic diseases.
A study by University of Leicester researchers has identified distinct biological variations in lung tissue samples that can help differentiate between mild and moderate/severe asthma. The findings may lead to the development of targeted treatments for specific subtypes of asthma, improving patient care.
The study found that using Asthma APGAR tools reduced asthma-related emergency department, urgent care, or hospital visits by 50% and improved asthma control by 14% compared to usual care. The tools also increased adherence to National Asthma Education and Prevention Program guidelines.
A randomized controlled trial found that mindfulness meditation training reduced the incidence of major depressive disorder by 11% compared to usual care, while also improving depression symptoms. Additionally, comprehensive asthma management tools improved asthma control and reduced hospital visits in primary care practices.
A recent study by Johns Hopkins researchers found previously known skin itch receptors in the airways of mice, which appear to contribute to bronchoconstriction and airway hypersensitivity. The discovery may be a promising new target for developing drug therapies for asthma and other respiratory disorders.