Articles tagged with Asthma
Researchers at the University of Manchester have developed a new understanding of asthma medicines through x-ray CT scanning, revealing the microstructure of individual particles. This innovation could lead to improved asthma medications and better quality control.
Researchers at Edith Cowan University have developed a way to detect and quantify wheat proteins that trigger intestinal inflammation and chronic ailments. This breakthrough has resulted in a reference map of wheat proteins across diverse varieties and an innovative technique to measure specific proteins.
Critical Path Institute (C-Path) has been awarded a U.S. Food and Drug Administration (FDA) contract to develop novel clinical outcome assessments for pediatric asthma. The project aims to create patient-focused drug development tools for children with asthma.
After four Louisville, Kentucky, coal-fired power plants either retired coal or installed stricter emissions controls, local residents' asthma symptoms and related hospitalizations and ED visits dropped dramatically. The study found nearly 400 avoided hospitalizations and ED visits each year across Jefferson County.
Researchers found that a ketogenic diet significantly reduced inflammation and mucus production in asthmatic mice. The diet's effect was attributed to its ability to slow down the division activity of immune cells, which play a central role in asthma symptoms.
A new study finds that using bedroom air filters can significantly improve breathing in asthmatic children. Consistent daily use of filters for two weeks reduced airway resistance, lung inflammation, and increased airway elasticity. The findings suggest that the filters may help prevent asthma flare-ups without costly medications.
A new review published in Nutrition Reviews suggests that a plant-based diet can help prevent and manage asthma. The study found that consuming fruits, vegetables, whole grains, and other high-fiber foods can be beneficial for asthma patients, whereas dairy products and high-fat foods can exacerbate symptoms.
Research finds that high levels of iron build-up in lung cells worsen asthma symptoms and lower lung function. The study suggests a link between iron absorption, immune system responses, and asthma severity.
Researchers found that Aspergillus molds attack the lung's epithelial cells, causing a leaky barrier and triggering an overreaction to future mold exposure. The TRPV4-calcium pathway plays a key role in this response, suggesting new avenues for preventing asthma.
A recent study found that children who received federal rental assistance had better asthma outcomes, including lower rates of diagnosis and emergency department visits. The research suggests that stable housing can improve lung function and overall health in children with asthma.
A study published in The Journal of Allergy and Clinical Immunology: In Practice found that children with food protein-induced enterocolitis syndrome (FPIES) are at a higher risk of developing other allergic conditions. Despite this, the researchers did not find a direct causal link between FPIES and these other allergies.
A study of 1,177 mother-infant pairs found exclusive breastfeeding for the first 3 months linked with a lower risk of respiratory allergies and asthma. Breastfeeding duration was insufficient to reduce the risk if not accompanied by family history of asthma.
A recent study published in Arthritis & Rheumatology found that asthma and chronic obstructive pulmonary disease (COPD) are associated with a higher risk of developing rheumatoid arthritis. Women with asthma were 53% more likely to develop rheumatoid arthritis, while those with COPD were 89% more likely.
A breakthrough discovery by Trinity College Dublin researchers identifies Caspase-11 as a key driver of allergic inflammation in asthma. This finding holds great promise for developing new therapeutic options to treat the debilitating disease.
A study analyzing global data found that chronic respiratory diseases have increased by 18% between 1990 and 2017, with the poorest regions experiencing the greatest disease burden. Smoking, environmental pollution, and body weight were identified as key risk factors for deaths and disability.
A new study finds that young infants exposed to common household cleaning products are more likely to develop childhood wheeze and asthma by three years of age. The study, published in the Canadian Medical Association Journal, suggests that chemicals in cleaning products can damage respiratory tract cells, increasing the risk of asthma.
Research found early exposure to household cleaning products increases risk of childhood asthma and wheeze by age 3, with scented products posing the highest risk. The study suggests avoiding or reducing use of sprays and fragrance-based cleaners to minimize a child's exposure and reduce the risk of respiratory issues.
A new study found that Prescription Drug List (PDL) coverage for preventive asthma medications can reduce financial burden and increase medication adherence. However, barriers to PDL use include lack of awareness, exclusions, and inconsistent benefits.
A new study by ISGlobal found that nearly half of all childhood asthma cases in Barcelona are attributable to air pollution. The study highlights the impact of air pollution on socioeconomic groups, particularly the less disadvantaged children.
Scientists have discovered the detailed structure of two calcium homeostasis modulator (CALHM) pores, which play a crucial role in sensing taste and controlling airways in lungs. The findings suggest these pores are essential for cell health and may lead to new therapies for Alzheimer's and depression.
Redlining practices in the 1930s are associated with higher rates of emergency department visits due to asthma, with a 39% increased risk in previously redlined neighbourhoods compared to non-redlined areas. Historical policies may have shaped neighbourhood development and air quality, contributing to asthma incidence.
Researchers identified a variant in the HSD3B1 gene associated with resistance to glucocorticoids in severe asthma patients. The study suggests that genetic testing may help tailor treatment strategies for individuals with severe asthma, offering new hope for improved management of this chronic condition.
A new study has identified a genetic anomaly associated with poor response to glucocorticoid asthma treatment. The research found that patients with the HSD3B1(1245A) variant are less likely to respond to treatment and may develop severe asthma.
A new educational outreach training package has shown effectiveness in managing respiratory diseases like COPD and asthma in Brazil. The Practical Approach to Care Kit (PACK) provides basic, cost-effective ways to diagnose and treat these common, severe diseases.
A new study suggests that lowering exposure to mouse allergens can lead to improved lung growth in asthmatic children living in low-income neighborhoods. The research found a strong association between mouse allergen exposure and lung function growth, with potential implications for long-term lung health and even longevity.
A recent study found that consistent use of nasal saline and corticosteroid sprays can significantly reduce the need for antibiotics and oral steroids in individuals with chronic rhinosinusitis (CRS). This reduction can lead to fewer side effects associated with these medications, such as gastric issues and mood disturbances. By using ...
Researchers found that children with mild to moderate asthma who experienced worsening symptoms had distinct bacterial groups in their upper airways, while those with well-controlled asthma had different bacteria. Altering the airway microbiome could potentially help patients with asthma.
A new report published in the American Thoracic Society's journal shows that reductions in air pollution have fast and dramatic impacts on health-outcomes, including decreases in all-cause morbidity. The study found improvements in health were striking, with significant benefits among non-smokers.
Researchers used specialized MRI techniques to follow patients with mild to moderate asthma over six years, finding consistent ventilation defects that persist over time. The studies refute the long-held belief that these defects are random and widespread, opening up opportunities for patient-specific treatments.
Research published in the European Respiratory Journal found that women with severe asthma symptoms during pregnancy are at higher risk of pre-eclampsia, high blood pressure, and low birth weight. Babies born to these mothers are also more likely to have respiratory issues and congenital abnormalities.
A UMass Lowell professor has received a $1 million grant to advance his work on reducing asthma among low-income seniors. The program will install portable air filtration units in apartments with gas stoves to improve health outcomes.
Allergists warn that social media misinformation can lead to incorrect medical decisions for people with food allergies. Dr. David Stukus notes that online 'cures' and at-home testing are often unproven and misleading, while reputable sources should be consulted instead.
A recent study by the American College of Allergy and Asthma found that most pediatric allergy patients are satisfied with telemedicine visits for allergies and asthma. Among surveyed parents, 37% were more satisfied, while 63% reported equal satisfaction, indicating a positive experience with telemedicine appointments.
A new study shows an association between a family history of cancer and childhood asthma diagnosis in over 20% of children, highlighting the importance of extra asthma screening efforts.
A school-based telehealth program has been shown to reduce emergency department visits for children with asthma living in a rural and underserved region of South Carolina. The study found that children with access to the program were 21% less likely to visit the ED for their asthma.
La Jolla Institute of Immunology and Seqster partner to accelerate discovery of personalized treatments for severe asthma through longitudinal data analysis. The collaboration enables 5000 participants to share medical records, genomic data, and wearable device data with researchers.
A Swedish study analyzed over 2.5 million births between 1973 and 1997 to examine the health outcomes of people born prematurely. The results show that 54.6% of those born preterm remained healthy without major conditions such as asthma, hypertension, or epilepsy by age 43, compared to 63% of full-term births.
A recent study published in the European Respiratory Journal has provided evidence that fatty tissue builds up in the airway walls of individuals who are overweight or obese. This accumulation alters the normal structure of the airways and leads to inflammation in the lungs, which may contribute to increased asthma symptoms.
Researchers found that ALS patients with a specific genetic variation in the IL6 receptor gene experience more severe symptoms and faster disease progression. The study suggests this polymorphism may serve as a target for new treatments and lay the groundwork for future clinical trials.
Research found that introducing fish or cod liver oil early in life significantly reduces the occurrence of eczema, wheezing and asthma at age six. Children who consumed fish weekly until two years old showed a 28-40% lower risk.
Researchers at LSU Health New Orleans found that asthma status reversed the relationship between neighborhood disadvantage and obesity in African American adolescent females. The study analyzed data from 129 participants and found that those with asthma were less likely to be obese compared to those without asthma.
A Norwegian study by the University of Bergen found that obese boys between 8 and their voice break age have double the risk of having children with asthma compared to non-obese peers. The connection is attributed to the development of reproductive cells during this period.
A recent study by UCSF researchers found that young adults with food insecurity are more likely to develop disorders associated with obesity and obstructive airway diseases like asthma. Chronic stress from food insecurity can lead to inflammation, insulin resistance and increased risk of mental health issues.
A study found that nearly a third of patients with severe asthma are taking harmful doses of oral steroids. Improving adherence to inhaled therapies and inhaler technique can help avoid this. However, only half of eligible patients receive biologic asthma drugs, which could reduce exposure to harmful oral steroids.
A new triple-therapy inhaler combining a steroid preventer, long-acting bronchodilator, and muscarinic antagonist significantly improved lung function and reduced moderate to severe asthma attacks. Patients with uncontrolled asthma who used the inhaler saw increased airway obstruction clearance and fewer exacerbations.
Researchers found that women with asthma are more likely to have lower levels of free testosterone and estradiol compared to those without asthma. Elevated sex hormone levels were associated with reduced odds of asthma in both men and women, particularly obese individuals.
Researchers found that African American children respond better to increasing inhaled corticosteroids or adding long-acting beta agonists compared to step-up therapies. The study highlights the need for tailored treatment approaches for subgroups of asthma patients, particularly those with African ancestry.
A new study found that almost half of young African American children responded better to increasing inhaled corticosteroid doses than adding long-acting bronchodilators. For adolescents and adults, most showed improved responses with adding a long-lasting bronchodilator, but some had no difference.
Children with asthma who also have depression and anxiety are more likely to visit the ER, with a rate of 28 visits per 100 child years compared to 16 for those without mental health diagnoses. This population may benefit from more intensive care coordination to improve medication compliance and symptom recognition.
Researchers identified links between genetic variants and early activation of memory T cells, suggesting problems with regulating this process could lead to immune diseases. The study's findings could help narrow down the search for molecular pathways involved in immune diseases.
Researchers found that certain flavored e-cigarette flavors, even without nicotine, can exacerbate asthma symptoms and increase tissue scarring. Flavors like Black Licorice and Banana Pudding were particularly problematic.
A Finnish study found that individuals with more allergic diseases are at higher risk for developing adult-onset asthma, especially among those born after 1940. The research suggests that even one allergic disease can approximately double the asthma risk, while three or more diseases can quadruple it.
A study by Karolinska Institutet shows that a mobile phone-based treatment adjustment algorithm can improve symptoms and medication adherence in uncontrolled asthma sufferers. The digital tool, AsthmaTuner, analyzes lung function and symptoms to provide personalized feedback and treatment recommendations.
Researchers discovered two distinct sub-populations of interstitial macrophages in the lung, which play a crucial role in preventing asthma development. These sub-populations exhibit different functions, origins, and morphologies, and have distinct local precursors.
A study by Finnish Institute for Health and Welfare found that large amounts of certain bacteria from outdoors may protect children from asthma. High diversity of microbes is important in protecting against asthma, but certain soil microbes provide more effective protection.
By creating a microdevice that mimics the behavior of human airways, researchers have discovered how muscle contraction in the airway causes breathing difficulties in people with asthma. This breakthrough could lead to new treatment strategies for respiratory diseases.
Children with mild asthma can effectively manage their condition by using inhalers when symptoms occur, reducing steroid medication use by almost 75%.
Researchers are developing technology to predict when a child will have an asthma attack and provide prevention and treatment suggestions. The system tracks geographical location, physical activity, air quality, and health data using smart phones, watches, and sensors.
A study published by the Barcelona Institute for Global Health found that air pollution from particulate matter (PM2.5), nitrogen dioxide (NO2), and black carbon is responsible for 33% of new childhood asthma cases in Europe, highlighting the need to update WHO air quality guidelines to better protect children's health.
A new study has identified 141 genetic regions associated with the risk of developing asthma, hay fever and eczema. The research also found that many patients diagnosed with one disease develop the others at some stage in life.