Research on asthma and respiratory disease. Covers brain-structure links, prevention trials, weight-loss drugs, and exercise for symptom control.
Researchers at Massachusetts General Hospital identified four biologically meaningful subtypes of RSV bronchiolitis, with one subtype linked to a 40% risk of developing asthma by age five. This study provides new insights into the complexity of bronchiolitis and may help improve care for affected children.
Dr. Sarah Goff's study examines the effects of Medicaid ACOs on asthma outcomes for children, aiming to improve pediatric asthma care and address social determinants of health. The research may inform other states considering ACO models for their Medicaid programs.
A new study suggests that exempting asthma medications from the deductible in high-deductible health plans may reduce medication use and exacerbations in children, but not adults. The research found small decreases in annual fills for some controller medications among children switching to HDHPs.
A new class of diabetes medication, GLP-1 receptor agonists, has been shown to improve asthma symptoms and reduce lung inflammation in patients with type 2 diabetes. The study found that these medications can help control asthma exacerbations and reduce breathing symptoms.
The NAVIGATOR study showed that tezepelumab significantly reduced annualized asthma exacerbation rates across all eosinophil level subgroups, including a 70% reduction in EOS ?300. The therapy also prolonged the time to first exacerbation requiring hospitalization or ED visit.
Researchers found that adding a third drug to dual-drug inhalers can reduce severe asthma exacerbations and improve asthma control in children, adolescents, and adults with moderate-to-severe asthma. The study included data from 20 randomized controlled trials involving almost 12,000 patients.
Children with a family history of asthma are two to three times more likely to develop the condition by age 4. Research also found that black children have higher asthma rates than white children during preschool years, but the gap closes later in childhood.
Researchers found that individuals with asthma living in historically redlined neighborhoods have lower lung function than those in non-redlined areas. This association was independent of race and co-occurring diseases, suggesting that environmental factors play a significant role in worsening asthma outcomes in these communities.
A web-based survey found that e-cigarette users had a higher risk of asthma, wheezing, and shortness of breath compared to non-users. The study also showed that past 30-day e-cigarette use was associated with increased respiratory symptoms even after controlling for cigarette and cannabis use.
Research presented at ATS 2021 International Conference found that e-cigarette users have a higher odds of developing asthma and having asthma attacks. Current smokers also had an increased risk, with former smokers facing the highest odds.
A population-based study found that children born in Sarnia, Ontario have a higher risk of developing asthma compared to neighboring cities. Air pollution exposure in the first year of life was associated with the development of asthma in children.
The study found that nearly half of people with asthma closest to the fire were unaware of the pollution problem and unable to take steps to avoid exposure. The incident led to an 80% increased risk of worsened asthma symptoms for those living within a 10-mile radius of the plant.
The NIH has established a new clinical research network called Childhood Asthma in Urban Settings (CAUSE) to study pediatric asthma in low-income urban settings. The network aims to develop tailored treatment and prevention approaches for children living in these communities.
A study published in eLife found that an overgrowth of yeast in the gut within the first few months of life may increase the risk of asthma later on. The period after birth is critical for immune system development and gut microbiome health, and disruptions to gut bacteria can lead to asthma.
A new study identifies non-Th2, or non-atopic childhood asthma, as a distinct disease with early exposure to airborne Benzo[a]pyrene linked to its development. The findings suggest that air pollution is a likely contributor to the most severe form of asthma.
A recent study has identified two distinct immune profiles in severe asthma patients, which could lead to personalized treatment approaches. The research, conducted by a team of scientists at the University of Pittsburgh and Stanford University, used advanced tools to characterize immune cells within the airways of severe asthma patients.
The Binational Early Asthma and Microbiome Study (BEAMS) examines how the 'hygiene hypothesis' affects children's risk of asthma in Mexico and the US. The study explores the role of microbiomes, family health history, and environmental exposures in developing asthma.
The study reveals that air pollution in the San Francisco Bay Area causes over 3,000 deaths and 5,500 new childhood asthma cases each year. Health impacts vary dramatically within neighborhoods, with certain areas experiencing a much larger burden.
During the COVID-19 pandemic, fewer people with severe asthma attacks sought medical help or were hospitalized for asthma exacerbations. A combination of factors, including reduced air pollution and improved self-management, may have contributed to this reduction. Additionally, a study in South Korea found a decrease in hospital admiss...
A school-based telehealth program in South Carolina provides accessible care to underserved children, improving academic performance and reducing ER visits. The program uses a time-efficient process that removes geographic barriers, ensuring timely treatment and medication administration.
Researchers discover that serotonin release from mast cells contributes to airway hyperresponsiveness in asthma, revealing a new mechanism for this common respiratory disease. The study uses a mouse model of asthma to demonstrate how mast cells react to methacholine, leading to increased airway constriction.
Researchers have identified a gene variant associated with childhood asthma using a diverse patient population. The study found that African Americans were more likely to carry the protective variant, which resulted in an increased risk of developing asthma.
A new study reviews data from 57 studies and finds that people with asthma have a 14% lower risk of getting COVID-19 and are significantly less likely to be hospitalized. The study included over 350,000 participants and found no apparent difference in the risk of death from COVID-19 in people with asthma.
Using sensor-based asthma inhalers may improve control of the condition and enhance the quality of life for caregivers. The study found that non-Hispanic Black participants experienced the greatest gains in asthma symptom control.
A new five-year study of over 100,000 people in Wales found that those from deprived backgrounds have worse asthma outcomes, including higher hospital admissions and risk of death. The study highlights the need for targeted health education strategies to improve asthma management in these communities.
Research published in the Archives of Disease in Childhood suggests a link between fetal exposure to antibiotics in mid-to-late pregnancy and an increased risk of childhood asthma. The study found that children born vaginally were more likely to develop asthma, with higher odds for more serious cases.
A Swedish study found a significant association between proton pump inhibitor use in children and adolescents and the development of asthma. The researchers analyzed data from over 10,000 children and adolescents, revealing a higher risk of asthma among those taking PPIs for gastrointestinal issues.
A study of over 100,000 patients found a significant drop in asthma attack rates during the first Covid-19 lockdown, with milder attacks being reduced, but potential biases due to hospitalization data. The results suggest lower air pollution and fewer cold and flu infections may have played a role in the observed decrease.
A study found that Black children have significantly higher rates of shellfish and fish allergies, as well as wheat allergy, compared to White children. The study also showed a higher prevalence of asthma in Black children with food allergies, highlighting the importance of reducing exposure to cockroaches.
Research into INNA-X shows it is effective against rhinovirus, the main cause of the common cold, reducing viral load and inflammation. The nasal spray works by stimulating the innate immune system, making it harder for viruses to take hold.
A new study suggests that consuming long chain omega-3 fatty acids in childhood can reduce the risk of developing asthma, but only in children with a specific genetic make-up. The research found a significant association between higher intake of long chain omega-3 fatty acids and lower risk of asthma.
A new study at Karolinska Institutet in Sweden has developed a urine test to identify and verify the type of asthma. The test uses lipid biomarkers to measure urinary metabolite levels of certain prostaglandins and leukotrienes, which are known mediators of asthmatic airway inflammation.
A study published in Thorax found that higher intake of advanced glycation end-products (AGEs) from non-seafood meats is associated with increased wheezing in children. Researchers examined data from the National Health and Nutrition Examination Survey and found a significant link between AGE intake and respiratory symptoms.
Research published in Thorax journal links advanced glycation end products (AGEs) from cooked meat to increased risk of childhood wheezing and respiratory symptoms. Higher AGE scores were associated with increased odds of wheezing, sleep disruptions, and medication use.
A new study published in PLOS ONE found that maternal asthma medication is associated with an increased risk of premature births and small birth weights. The study analyzed data from over 117,000 births in Wales and found that prescriptions for asthma medicines were linked to lower birth weights and higher rates of preterm birth.
A new survey found that nearly a third of young adults with asthma do not comply with COVID-19 guidelines, highlighting the need for healthcare professionals to advise patients on basic measures and medication use. The study also revealed alarming misconceptions about COVID-19 risk among asthmatic individuals.
Researchers from RUDN University have developed a new method to analyze cytokines in nasal swabs to predict disease flow and prevent complications in asthma patients with accompanying diseases. The study found that monitoring specific cytokine profiles can help identify dangerous tendencies and allow for timely intervention.
A new study published in the Annals of the American Thoracic Society found a significant decrease in pediatric asthma-related emergency department visits during the spring 2020 COVID-19 lockdown. The rate of ED visits dropped by 80% compared to previous years, indicating improved symptom control and reduced exacerbations.
A large long-term study found that hormonal contraceptives may lower the risk of severe asthma bouts in women of reproductive age. However, the protective effect is relatively small and does not include progestogen-only Pill.
Researchers found a link between microorganisms in bed dust and children's bacteria, suggesting a potential reduction in asthma and allergy risks. The study analyzed bed dust samples from 577 infants and respiratory samples from 542 children, revealing a correlation between the two.
A study of 214 children found that final diagnoses differ from referral diagnoses in 54% of cases, with asthma being the most common cause. Inhaling medication was prescribed to 91% of children with a final diagnosis of asthma, while physiotherapy was recommended for 50% of those with dysfunctional breathing.
A study of 286,825 participants found a significant association between permanent night shift work and moderate to severe asthma. The researchers suggest that adapting shift work schedules to individual chronotype may be a worthwhile public health measure.
A new study reveals that COVID-19 has led to an increase in asthma visits via telemedicine, with show rates for children with asthma being significantly higher than expected. Additionally, over 90% of patients reported well-controlled asthma during telemedicine visits.
A new study by the American College of Allergy, Asthma, and Immunology found that food allergies negatively affect the quality of life of those who suffer from them, particularly for Asian patients and their parents. The study showed higher negative quality of life scores for Asians compared to white and Black patients.
A new study found that hospitalized patients with COVID-19 and allergic conditions have similar rates of ICU admission and severity of disease. Researchers examined hospital data from 275 patients and found no significant differences in interventions needed for those with allergies versus those without.
Researchers found that children born by caesarean section have an increased risk of developing asthma if their gut microbiota still carries a caesarean signature at age 1 year. This study proposes restoring the perturbed microbiome to potentially prevent asthma development in high-risk children.
A study by Massachusetts General Hospital found that expanded access to health insurance significantly reduced ambulance dispatches for asthma emergencies in New York City. Improved access to outpatient management of the chronic condition is believed to be the likely reason for this decline.
Researchers found that C-section birth doubles asthma and allergy risk, but recovery of gut microbiota by age 1 may prevent this. The study suggests restoring the perturbed microbiome could prevent asthma development in high-risk children.
Researchers at La Jolla Institute for Immunology have discovered that blocking OX40L and CD30L, two key immune molecules, is crucial to preventing asthma attacks. The study shows how these molecules contribute to inflammation in the lungs during an allergic reaction.
Potentially preventable hospitalizations among older adults are more common among Black and Hispanic Americans. Researchers found that increasing primary care access and affordable healthcare can reduce these hospitalizations.
Working in farming or wood industries with asthma significantly increases the risk of hospitalization due to worsening symptoms. Asthmatics exposed to dust are more than twice as likely to be hospitalized for asthma compared to those without exposure, according to a recent Aarhus University study.
A recent study by Helmholtz Munich researchers found that a diverse environmental microbiome, particularly in farm children, can protect against childhood asthma. The gut microbiome plays a crucial role in this protective effect, with certain bacteria producing short-chain fatty acids that may contribute to asthma protection.
Research suggests that psychological distress during pregnancy may be linked to a heightened risk of asthma and poorer lung function in children. The study found that mothers' overall psychological distress was associated with a 45-92% increased risk of current asthma in their children, while fathers' symptoms had no association.
A new study from North Carolina State University found that several widely available interventions are associated with reduced medical costs and a lower likelihood of emergency room visits or hospitalizations for children with asthma. The interventions include asthma self-management education, flu vaccine, spacer use, and nebulizer use.
A new study found that asthma and food hypersensitivity in children are associated with an increased risk of developing irritable bowel syndrome (IBS) during adolescence. Children with IBS were nearly twice as likely to have had asthma, and almost half reported food hypersensitivity.
Researchers investigated whether avoiding cow's milk formula after birth affects young children's risk of developing asthma. The study found a significant decrease in recurrent wheeze among children who did not receive cow's milk formula.
A new study found that wildfire smoke leads to a 6.1% increase in medical visits for asthma patients compared to days with similar pollution levels from other sources. The research team suggests that wildfire PM is more hazardous than non-wildfire PM for asthma patients, likely due to differences in chemical composition or human behavior.
More than one quarter of asthma patients were prescribed excessive amounts of steroid tablets, posing a risk of serious side effects. Researchers recommend using preventer inhalers as the best way to avoid or minimize steroid use and its associated risks.
A new trial suggests that children with asthma may benefit from personalized treatment based on genetic differences. The study found that children with two copies of a specific gene variant experienced an average improvement in quality of life score of 0.42.
People who had bronchitis at least once before the age of seven are more likely to develop lung problems in later life. Childhood bronchitis was linked to increased risks of pneumonia and asthma in middle age, with stronger associations found for those with more frequent episodes.