A population-based study found that children born in Sarnia, Ontario have a higher risk of developing asthma compared to neighboring cities. Air pollution exposure in the first year of life was associated with the development of asthma in children.
SourceLawson Health Research Institute·JournalCMAJ Open·DateMay 4, 2021
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The study found that nearly half of people with asthma closest to the fire were unaware of the pollution problem and unable to take steps to avoid exposure. The incident led to an 80% increased risk of worsened asthma symptoms for those living within a 10-mile radius of the plant.
SourceUniversity of Pittsburgh·JournalJournal of Allergy and Clinical Immunology·DateApr 28, 2021
The NIH has established a new clinical research network called Childhood Asthma in Urban Settings (CAUSE) to study pediatric asthma in low-income urban settings. The network aims to develop tailored treatment and prevention approaches for children living in these communities.
SourceNIH/National Institute of Allergy and Infectious Diseases·DateApr 23, 2021
A study published in eLife found that an overgrowth of yeast in the gut within the first few months of life may increase the risk of asthma later on. The period after birth is critical for immune system development and gut microbiome health, and disruptions to gut bacteria can lead to asthma.
A new study identifies non-Th2, or non-atopic childhood asthma, as a distinct disease with early exposure to airborne Benzo[a]pyrene linked to its development. The findings suggest that air pollution is a likely contributor to the most severe form of asthma.
SourceLehigh University·JournalEnvironmental Health·DateApr 13, 2021
A recent study has identified two distinct immune profiles in severe asthma patients, which could lead to personalized treatment approaches. The research, conducted by a team of scientists at the University of Pittsburgh and Stanford University, used advanced tools to characterize immune cells within the airways of severe asthma patients.
SourceUniversity of Pittsburgh·JournalCell Reports·DateApr 13, 2021
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The Binational Early Asthma and Microbiome Study (BEAMS) examines how the 'hygiene hypothesis' affects children's risk of asthma in Mexico and the US. The study explores the role of microbiomes, family health history, and environmental exposures in developing asthma.
SourceUniversity of Arizona Health Sciences·DateApr 7, 2021
The study reveals that air pollution in the San Francisco Bay Area causes over 3,000 deaths and 5,500 new childhood asthma cases each year. Health impacts vary dramatically within neighborhoods, with certain areas experiencing a much larger burden.
SourceGeorge Washington University·JournalEnvironmental Health Perspectives·DateMar 31, 2021
During the COVID-19 pandemic, fewer people with severe asthma attacks sought medical help or were hospitalized for asthma exacerbations. A combination of factors, including reduced air pollution and improved self-management, may have contributed to this reduction. Additionally, a study in South Korea found a decrease in hospital admiss...
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A school-based telehealth program in South Carolina provides accessible care to underserved children, improving academic performance and reducing ER visits. The program uses a time-efficient process that removes geographic barriers, ensuring timely treatment and medication administration.
SourceMedical University of South Carolina·JournalThe Journal for Nurse Practitioners·DateMar 24, 2021
Researchers discover that serotonin release from mast cells contributes to airway hyperresponsiveness in asthma, revealing a new mechanism for this common respiratory disease. The study uses a mouse model of asthma to demonstrate how mast cells react to methacholine, leading to increased airway constriction.
Researchers have identified a gene variant associated with childhood asthma using a diverse patient population. The study found that African Americans were more likely to carry the protective variant, which resulted in an increased risk of developing asthma.
SourceHenry Ford Health·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateFeb 25, 2021
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A new study reviews data from 57 studies and finds that people with asthma have a 14% lower risk of getting COVID-19 and are significantly less likely to be hospitalized. The study included over 350,000 participants and found no apparent difference in the risk of death from COVID-19 in people with asthma.
SourceTaylor & Francis Group·JournalJournal of Asthma·DateFeb 18, 2021
Using sensor-based asthma inhalers may improve control of the condition and enhance the quality of life for caregivers. The study found that non-Hispanic Black participants experienced the greatest gains in asthma symptom control.
SourceAnn & Robert H. Lurie Children's Hospital of Chicago·JournalPEDIATRICS·DateFeb 17, 2021
A new five-year study of over 100,000 people in Wales found that those from deprived backgrounds have worse asthma outcomes, including higher hospital admissions and risk of death. The study highlights the need for targeted health education strategies to improve asthma management in these communities.
SourceSwansea University·JournalPLOS Medicine·DateFeb 16, 2021
Research published in the Archives of Disease in Childhood suggests a link between fetal exposure to antibiotics in mid-to-late pregnancy and an increased risk of childhood asthma. The study found that children born vaginally were more likely to develop asthma, with higher odds for more serious cases.
SourceBMJ Group·JournalArchives of Disease in Childhood·DateFeb 9, 2021
A Swedish study found a significant association between proton pump inhibitor use in children and adolescents and the development of asthma. The researchers analyzed data from over 10,000 children and adolescents, revealing a higher risk of asthma among those taking PPIs for gastrointestinal issues.
SourceJAMA Network·JournalJAMA Pediatrics·DateFeb 8, 2021
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A study of over 100,000 patients found a significant drop in asthma attack rates during the first Covid-19 lockdown, with milder attacks being reduced, but potential biases due to hospitalization data. The results suggest lower air pollution and fewer cold and flu infections may have played a role in the observed decrease.
SourceUniversity of Edinburgh·JournalThorax·DateFeb 8, 2021
A study found that Black children have significantly higher rates of shellfish and fish allergies, as well as wheat allergy, compared to White children. The study also showed a higher prevalence of asthma in Black children with food allergies, highlighting the importance of reducing exposure to cockroaches.
SourceAnn & Robert H. Lurie Children's Hospital of Chicago·DateFeb 4, 2021
Research into INNA-X shows it is effective against rhinovirus, the main cause of the common cold, reducing viral load and inflammation. The nasal spray works by stimulating the innate immune system, making it harder for viruses to take hold.
SourceHunter Medical Research Institute·JournalEuropean Respiratory Journal·DateFeb 1, 2021
A new study suggests that consuming long chain omega-3 fatty acids in childhood can reduce the risk of developing asthma, but only in children with a specific genetic make-up. The research found a significant association between higher intake of long chain omega-3 fatty acids and lower risk of asthma.
SourceQueen Mary University of London·JournalEuropean Respiratory Journal·DateJan 27, 2021
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A new study at Karolinska Institutet in Sweden has developed a urine test to identify and verify the type of asthma. The test uses lipid biomarkers to measure urinary metabolite levels of certain prostaglandins and leukotrienes, which are known mediators of asthmatic airway inflammation.
SourceKarolinska Institutet·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJan 13, 2021
A study published in Thorax found that higher intake of advanced glycation end-products (AGEs) from non-seafood meats is associated with increased wheezing in children. Researchers examined data from the National Health and Nutrition Examination Survey and found a significant link between AGE intake and respiratory symptoms.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalThorax·DateDec 22, 2020
Research published in Thorax journal links advanced glycation end products (AGEs) from cooked meat to increased risk of childhood wheezing and respiratory symptoms. Higher AGE scores were associated with increased odds of wheezing, sleep disruptions, and medication use.
A new study published in PLOS ONE found that maternal asthma medication is associated with an increased risk of premature births and small birth weights. The study analyzed data from over 117,000 births in Wales and found that prescriptions for asthma medicines were linked to lower birth weights and higher rates of preterm birth.
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A new survey found that nearly a third of young adults with asthma do not comply with COVID-19 guidelines, highlighting the need for healthcare professionals to advise patients on basic measures and medication use. The study also revealed alarming misconceptions about COVID-19 risk among asthmatic individuals.
SourceTaylor & Francis Group·JournalJournal of Asthma·DateDec 9, 2020
Researchers from RUDN University have developed a new method to analyze cytokines in nasal swabs to predict disease flow and prevent complications in asthma patients with accompanying diseases. The study found that monitoring specific cytokine profiles can help identify dangerous tendencies and allow for timely intervention.
SourceRUDN University·JournalWorld Allergy Organization Journal·DateDec 5, 2020
A new study published in the Annals of the American Thoracic Society found a significant decrease in pediatric asthma-related emergency department visits during the spring 2020 COVID-19 lockdown. The rate of ED visits dropped by 80% compared to previous years, indicating improved symptom control and reduced exacerbations.
SourceAmerican Thoracic Society·JournalAnnals of the American Thoracic Society·DateDec 4, 2020
A large long-term study found that hormonal contraceptives may lower the risk of severe asthma bouts in women of reproductive age. However, the protective effect is relatively small and does not include progestogen-only Pill.
Researchers found a link between microorganisms in bed dust and children's bacteria, suggesting a potential reduction in asthma and allergy risks. The study analyzed bed dust samples from 577 infants and respiratory samples from 542 children, revealing a correlation between the two.
SourceUniversity of Copenhagen - Faculty of Science·JournalMicrobiome·DateNov 19, 2020
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A study of 214 children found that final diagnoses differ from referral diagnoses in 54% of cases, with asthma being the most common cause. Inhaling medication was prescribed to 91% of children with a final diagnosis of asthma, while physiotherapy was recommended for 50% of those with dysfunctional breathing.
A study of 286,825 participants found a significant association between permanent night shift work and moderate to severe asthma. The researchers suggest that adapting shift work schedules to individual chronotype may be a worthwhile public health measure.
A new study reveals that COVID-19 has led to an increase in asthma visits via telemedicine, with show rates for children with asthma being significantly higher than expected. Additionally, over 90% of patients reported well-controlled asthma during telemedicine visits.
SourceAmerican College of Allergy, Asthma, and Immunology·DateNov 13, 2020
A new study by the American College of Allergy, Asthma, and Immunology found that food allergies negatively affect the quality of life of those who suffer from them, particularly for Asian patients and their parents. The study showed higher negative quality of life scores for Asians compared to white and Black patients.
SourceAmerican College of Allergy, Asthma, and Immunology·DateNov 13, 2020
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A new study found that hospitalized patients with COVID-19 and allergic conditions have similar rates of ICU admission and severity of disease. Researchers examined hospital data from 275 patients and found no significant differences in interventions needed for those with allergies versus those without.
SourceAmerican College of Allergy, Asthma, and Immunology·DateNov 13, 2020
Researchers found that children born by caesarean section have an increased risk of developing asthma if their gut microbiota still carries a caesarean signature at age 1 year. This study proposes restoring the perturbed microbiome to potentially prevent asthma development in high-risk children.
SourceUniversity of Copenhagen·JournalScience Translational Medicine·DateNov 12, 2020
A study by Massachusetts General Hospital found that expanded access to health insurance significantly reduced ambulance dispatches for asthma emergencies in New York City. Improved access to outpatient management of the chronic condition is believed to be the likely reason for this decline.
SourceMassachusetts General Hospital·JournalJAMA Network Open·DateNov 11, 2020
Researchers found that C-section birth doubles asthma and allergy risk, but recovery of gut microbiota by age 1 may prevent this. The study suggests restoring the perturbed microbiome could prevent asthma development in high-risk children.
SourceRutgers University·JournalScience Translational Medicine·DateNov 11, 2020
Researchers at La Jolla Institute for Immunology have discovered that blocking OX40L and CD30L, two key immune molecules, is crucial to preventing asthma attacks. The study shows how these molecules contribute to inflammation in the lungs during an allergic reaction.
SourceLa Jolla Institute for Immunology·JournalJournal of Allergy and Clinical Immunology·DateNov 11, 2020
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Potentially preventable hospitalizations among older adults are more common among Black and Hispanic Americans. Researchers found that increasing primary care access and affordable healthcare can reduce these hospitalizations.
SourceAmerican Academy of Family Physicians·JournalThe Annals of Family Medicine·DateNov 10, 2020
Working in farming or wood industries with asthma significantly increases the risk of hospitalization due to worsening symptoms. Asthmatics exposed to dust are more than twice as likely to be hospitalized for asthma compared to those without exposure, according to a recent Aarhus University study.
A recent study by Helmholtz Munich researchers found that a diverse environmental microbiome, particularly in farm children, can protect against childhood asthma. The gut microbiome plays a crucial role in this protective effect, with certain bacteria producing short-chain fatty acids that may contribute to asthma protection.
SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))·JournalNature Medicine·DateNov 2, 2020
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A new study from North Carolina State University found that several widely available interventions are associated with reduced medical costs and a lower likelihood of emergency room visits or hospitalizations for children with asthma. The interventions include asthma self-management education, flu vaccine, spacer use, and nebulizer use.
SourceNorth Carolina State University·JournalJournal of Asthma·DateOct 12, 2020
Research suggests that psychological distress during pregnancy may be linked to a heightened risk of asthma and poorer lung function in children. The study found that mothers' overall psychological distress was associated with a 45-92% increased risk of current asthma in their children, while fathers' symptoms had no association.
A new study found that asthma and food hypersensitivity in children are associated with an increased risk of developing irritable bowel syndrome (IBS) during adolescence. Children with IBS were nearly twice as likely to have had asthma, and almost half reported food hypersensitivity.
Researchers investigated whether avoiding cow's milk formula after birth affects young children's risk of developing asthma. The study found a significant decrease in recurrent wheeze among children who did not receive cow's milk formula.
SourceJAMA Network·JournalJAMA Network Open·DateOct 2, 2020
A new study found that wildfire smoke leads to a 6.1% increase in medical visits for asthma patients compared to days with similar pollution levels from other sources. The research team suggests that wildfire PM is more hazardous than non-wildfire PM for asthma patients, likely due to differences in chemical composition or human behavior.
SourceDesert Research Institute·JournalEnvironmental Health·DateSep 22, 2020
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More than one quarter of asthma patients were prescribed excessive amounts of steroid tablets, posing a risk of serious side effects. Researchers recommend using preventer inhalers as the best way to avoid or minimize steroid use and its associated risks.
SourceUniversity of Queensland·JournalThe Medical Journal of Australia·DateSep 13, 2020
A new trial suggests that children with asthma may benefit from personalized treatment based on genetic differences. The study found that children with two copies of a specific gene variant experienced an average improvement in quality of life score of 0.42.
People who had bronchitis at least once before the age of seven are more likely to develop lung problems in later life. Childhood bronchitis was linked to increased risks of pneumonia and asthma in middle age, with stronger associations found for those with more frequent episodes.
Research reveals that babies born with higher levels of cadmium may be at increased risk of developing childhood asthma and allergies. Cadmium exposure has been found to interfere with immune systems and increase allergic reactions.
New research challenges assumption that asthma is a significant risk factor for severe COVID-19 hospitalization and intubation, finding lower prevalence rates among hospitalized patients compared to the general population.
SourceAmerican Thoracic Society·JournalAnnals of the American Thoracic Society·DateAug 31, 2020
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A placebo-controlled clinical trial found that vitamin D supplements did not prevent severe asthma attacks in at-risk children. The study, led by Juan C. Celedón, followed nearly 200 children with moderately low vitamin D levels for three years and showed no benefit from the supplements.
Research presented at the European Respiratory Society International Congress shows that babies exposed to levels of air pollution within EU standards develop poorer lung function as children and teenagers. Long-term exposure to air pollution is also linked to a higher risk of developing asthma in adults, according to a second study.
A new smartphone app can predict asthma deterioration by measuring night-time coughing, indicating worsening symptoms. The study found a strong correlation between increased night-time coughing and subsequent worsening of asthma symptoms, suggesting the app could be a useful tool for monitoring asthma.
Research found a 6% reduction in excessive prescribing of reliever inhalers after an electronic alert was introduced, with also increases in asthma reviews and reductions in exacerbations. The study suggests the alert prompts a review of patients who may have poor asthma control.
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Researchers have identified master regulator genes that causally regulate key biological processes underlying asthma. These genes provide a novel path forward for uncovering mechanisms and developing novel therapies for asthma. The study also identified nasal gene signatures for mild, moderate, and severe persistent asthma.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJournal of Allergy and Clinical Immunology·DateAug 20, 2020
A study published by The BMJ found that children exposed to high levels of fine air pollutants (PM2.5) are more likely to develop asthma and persistent wheezing. Higher levels of PM2.5, as well as exposure to other pollutants, were associated with an increased risk of developing these conditions.
Researchers found that two common genetic variations in the KIF3A gene impair skin barrier function, leading to increased water loss and development of atopic dermatitis. Genetic testing could help identify infants at risk, potentially preventing eczema and related allergic diseases.
SourceNIH/National Institute of Allergy and Infectious Diseases·JournalNature Communications·DateAug 14, 2020
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A review of 34 studies found that ß2-agonists improved anaerobic exercise performance by 5% in athletes without asthma, with significant benefits for sprint and strength performances. The oral route was more effective than inhalation, but the impact of WADA-approved versions remains uncertain.
SourceBMJ Group·JournalBritish Journal of Sports Medicine·DateAug 3, 2020