Researchers at Harvard have identified the mechanism for diffuse axonal injury and explained why cerebral vasospasm is more common in blast-induced brain injuries. Treating neural tissue with a ROCK inhibitor within minutes of injury may lead to viable treatments, according to the study.
Researchers found abnormal tau tangles and amyloid-beta plaques in survivors years after a single TBI, suggesting a potential link between the two conditions. The study suggests that a single TBI may initiate long-term neurodegenerative processes, offering new insights into the development of Alzheimer's disease.
Research found that premature infants with abnormal brain ultrasounds are at increased risk for specific psychiatric disorders. The study followed a group of premature infants until age 16 and found a relation between perinatal brain injuries and certain psychiatric disorders.
A history of psychiatric illness before TBI is strongly predictive of post-TBI psychiatric disorders. Psychiatric symptoms during the acute post-injury period and concurrent limb injuries also increase the risk of psychiatric illnesses.
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A recent study published in Rehabilitation Psychology found that TBI victims who feel a strong connection to a higher power experience better emotional and physical rehabilitation outcomes. Social support also played a significant role in positive health outcomes.
Research reveals a significant decline of up to 29% in bicycle-related head injuries immediately after NSW mandated helmet use. The study supports the maintenance of mandatory helmet laws, but cautions against seeing helmets as a panacea for bike safety.
A recent study published in CMAJ found that introducing bodychecking at the Pee Wee level reduces injury risk, particularly for Bantam players, with a 33% lower risk of more than seven days' loss from playing time.
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A public health approach is needed to prevent childhood sports injuries from leading to lifelong disabilities. The annual rate of catastrophic injury in sports is 6.9 per 100,000 participants, with many children and youth under age 21 affected.
A new study published in the Canadian Medical Association Journal found that introducing bodychecking into Bantam ice hockey does not increase overall injury rates or concussion risk, regardless of prior experience.
The US construction industry has the highest number of traumatic brain injuries (TBI), with a fatality rate of 0.8 per 100,000 workers per year. Falls are the leading cause of fatal TBI, accounting for 29% of all fatalities.
A recent study from the University of Michigan found that young people who have sustained a head injury are more likely to engage in violent behavior. The research also showed that recent head injuries were even more strongly linked to violent behavior.
Researchers used advanced imaging technique to detect blast-related injuries in US military personnel, finding abnormalities in brain white matter. These findings suggest fundamental differences between blast-related and civilian traumatic brain injuries.
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A study published in the journal Brain found that electrical disturbances in the brain, known as cortical spreading depolarizations, are associated with poor recovery and long-lasting outcomes after neurotrauma. These disturbances can be invisible on routine EEG exams but represent extreme changes in voltage.
Researchers have identified a protective molecule in the brain that can rescue damaged cells and prevent further damage. By artificially increasing levels of this compound, KCC2, scientists hope to develop new treatments for conditions like stroke, epilepsy, and Alzheimer's.
Researchers found that a gene called notum determines whether planarian regrow head or tail at amputation sites. This study suggests that animals can 'decide' what needs to be regenerated based on tissue orientation at wound sites.
A University of Illinois professor chaired a committee that recommends providing at least 50% of normal caloric intake, including higher protein, to reduce inflammation and promote brain repair in TBI patients. The guidelines aim to improve recovery rates for veterans and individuals with other traumatic brain injuries.
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Researchers discovered that wearing body armor fully protected mice brains from axonal nerve cell damage in critical parts of the brain. Body armor shielded mice from over 80% of axonal damage observed in the brain's visual pathways.
Researchers at Georgia Tech have developed a radar system that can detect concussions by analyzing a person's gait pattern. The system, which is faster and less intrusive than existing techniques, uses a 10.5 GHz continuous wave radar to identify anomalies in an individual's walk. This could help coaches and commanders quickly decide i...
A recent study of NHL concussions over seven seasons found that rates have declined, but the time lag between injury and return to play has increased. The study identified clinical signs and symptoms that predict longer game time losses, emphasizing the need for education and caution in managing concussions.
A study by neurosurgeons at the University of Rochester Medical Center found that anti-depressants can boost brain cells after injury, improving depression and memory. The medication, imipramine, increased the number of neurons in the hippocampus, a key area for memory, and enhanced novel object recognition tests.
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A major NHL concussion study found that while injury rates leveled out, the number of days lost per concussion has increased. Headache and low energy were significant predictors of post-concussion time loss.
Concussions are prevalent in junior hockey leagues, with up to 25% of players sustaining injuries. Banning bodychecking could decrease the risk of concussions, reducing their impact on academic and athletic performance. The proposal aims to break a vicious cycle where young athletes learn to play in a way that causes injury.
Researcher Theresa Pape is developing therapies to jump-start the lives of patients with traumatic brain injury, often falling through the cracks of the medical system. Her innovative clinical trials test the effectiveness of familiar voice intervention and transcranial magnetic stimulation in awakening patients.
A new journal, Therapeutic Hypothermia and Temperature Management, explores the use of therapeutic hypothermia to improve survival rates after out-of-hospital cardiac arrest. The therapy has been shown to reduce brain injury risk in approximately 400,000 people who suffer from cardiac arrest annually.
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Researchers at UT Southwestern Medical Center found that neural stem cells in the brain's memory area become activated after injury and remodel the area with newly generated nerve cells, but this process may be limited by a finite pool of stem cells.
Researchers at the University of Granada have found that early neuropsychological rehabilitation significantly reduces cognitive, emotional, and behavioral after-effects in patients with acquired brain injury. The study proves that treating cognitive, emotional, and behavioral skills simultaneously improves patient outcomes.
A study published in Open Medicine found that lowering the age of bodychecking significantly increases the risk of brain injuries among minor hockey players. The researchers analyzed records of 8,552 male youth and found that more than half of hockey-related injuries were caused by bodychecking.
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A new national study found a significant increase in boxing injuries, including head and neck injuries, among participants 6 years of age and older. The study also revealed that concussions among younger boxers are a growing concern due to potential long-term neurological implications.
A University of Colorado Boulder study indicates acupressure may improve cognitive function in individuals with mild traumatic brain injury. Researchers used a form of acupuncture called Jin Shin to stimulate specific points on the body and showed significant improvements in working memory and attention.
A new US study found an average of 9,500 injuries and over 100 deaths related to cribs, playpens and bassinets among children under 2 years old each year. The majority of injuries involved cribs, with the most common injury being soft-tissue injury.
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A study published in CMAJ found that nonmilitary personnel in Iraq and Afghanistan were more likely to be medically evacuated with non-war-related injuries, returning to duty after such injuries. Military personnel, however, were more likely to be evacuated for war-related injuries.
Researchers at UTHealth and Athersys found that MultiStem therapy reduced inflammatory damage in the brain and improved motor skills in rats with ischemic stroke. The study suggests potential benefits of stem cell therapy for treating stroke, with implications for improving recovery outcomes.
New research from Johns Hopkins Medicine suggests that motorcycle helmets are associated with a lower risk of cervical spine injury. The study found that helmeted riders were 22% less likely to suffer spinal injuries compared to those without helmets.
Medical College of Georgia researchers explore the role of aquaporin-4 in traumatic brain injuries, discovering that curcumin and brilliant blue G can block inflammation and swelling. The findings hold promise for improved treatment options for patients with TBI.
Warfarin users are more likely to die from traumatic injuries compared to non-users, especially among younger patients with severe head injuries. The study found a 50% increase in mortality from severe head injuries in patients under 65 on warfarin.
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Researchers at Virginia Tech-Wake Forest University Center for Injury Biomechanics will investigate blast-induced brain trauma using experimental and computational models. The project aims to develop safety mechanisms for soldiers and transport vehicles to reduce injuries.
Researchers found that SIK2 suppressed CREB-mediated gene expression after oxygen and glucose deprivation, increasing neuronal survival in mice lacking SIK2. The SIK2-TORC1-CREB signaling pathway may serve as a potential therapeutic target for promoting neuron survival.
Multidetector computed tomography (MDCT) can accurately pinpoint bullet trajectory angles, enabling investigators to determine sniper locations. This technology also has potential benefits in crime scene analysis and patient treatment, according to a recent study.
Researchers at Mount Sinai School of Medicine developed a web-based screening tool to assess Traumatic Brain Injury (TBI) in war veterans. The Brain Injury Screening Questionnaire (BISQ) is a low-cost, anonymous tool that detects symptoms such as sleep disturbances, irritability, and memory problems.
A recent study from Rhode Island Hospital found that sailing injuries on America's Cup boats are often caused by trips, falls, and collisions with fellow crew members. The majority of severe injuries were to the head, knee, leg, and arm, with heavy weather being a contributing factor in 36% of cases.
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Therapeutic hypothermia has been shown to reduce neurologic complications and improve outcomes for patients with traumatic brain injury. The optimal approach to administering the treatment depends on individual patient clinical conditions.
A synthetic derivative of turmeric has been found to be highly neuroprotective against ischemic stroke and traumatic brain injury in animal models. The compound, CNB-001, improved behavioral and molecular deficits in both conditions, offering potential clinical promise for current treatment-limited diseases.
Researchers found that magnetic resonance spectroscopy (MRS) can help diagnose chronic traumatic encephalopathy (CTE), a brain disorder caused by repetitive head trauma. The study revealed altered levels of neurochemicals in the brains of former athletes with suspected CTE, suggesting a potential non-invasive early detection method.
Researchers developed a color-changing patch to indicate blast exposure and potential brain injury risk. The badges use nanoscale structures that change color with intensity of exposure.
Researchers at MIT have created computer models that show a face shield can significantly reduce traumatic brain injury by impeding direct transmission of blast waves to the face. The study's findings offer a potential solution for preventing head injuries sustained by US troops during explosions.
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Researchers discovered a protein called glial fibrillary acidic protein (GFAP) that can predict brain injury and death in children on ECMO. High levels of GFAP were found to be associated with an increased risk of brain bleeding, swelling, stroke, and death.
The study identified eight categories of PTSD-related characteristics and factors, including exposure to traumatic stressors and mental health history. The work group's findings aim to improve the integration of knowledge regarding PTSD and TBI, ultimately benefiting trauma survivors.
New brain machine technologies show promise in restoring vision, controlling prosthetics with thoughts, and regaining limb function after injury. An artificial retina may restore vision more effectively than existing prosthetics.
The KINARM Assessment Station is an objective tool for assessing brain function, capturing subtle deficits not measured by traditional tests. Clinical researchers need this tool to develop better therapies for treating brain injury or disease.
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A new consensus on TBI and PTSD establishes common language, measurement, treatment, and potential outcomes, promoting greater consistency and collaboration among researchers. The set of papers provides recommendations for clinical research on TBI and psychological health, aiming to advance the field.
A new study reveals young offenders have a significantly higher rate of Traumatic Brain Injury (TBI) than expected in society. TBI was also linked to greater violence in offending and mental health problems. Researchers emphasize the need for brain injury assessment in offender management.
A recent study by Dr. Michael Cusimano found that existing headgear and mouth guards are ineffective in preventing concussions in rugby players, but educational injury prevention programs and rule changes can significantly reduce injuries.
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Researchers have found that brain damage continues to develop and evolve after traumatic brain injury, offering a potential target for treatments. The study, published in the Journal of Nuclear Medicine, provides new insights into progressive changes in brain structure and function after injury.
Microglia, immune cells long thought to be dormant, are found to constantly interact with synapses, creating and eliminating them. This discovery challenges current views of the brain and its functions.
Researchers discovered that microglia cells are constantly active and create and eliminate synapses, contributing to learning and memory. Microglia appear to be involved in creating or changing the extracellular space around synapses, affecting brain signaling.
A new study using positron emission tomography (PET) and magnetic resonance imaging (MRI) found that traumatic brain injuries lead to widespread decreases in brain functioning, particularly in the hippocampus. The research suggests a time window during which intervention could mitigate long-term neurological consequences.
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The American Academy of Neurology calls for athletes suspected of having a concussion to be removed from play until evaluation by a trained physician. This recommendation aims to prevent catastrophic results and promote high-quality, safe care for athletes in contact sports.
The grants will advance research on retinitis pigmentosa, Huntington's disease and traumatic brain injury. The selected projects are expected to result in candidate drugs or cell therapies, which can be developed for clinical trials.
A National Stroke Association survey reveals that 53% of stroke survivors suffer from pseudobulbar affect (PBA), a condition causing involuntary laughter or crying. PBA symptoms interfere with daily activities and relationships, but few are aware of the condition.
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A team of biomedical engineers has received a $6.25 million grant to study the effects of blast waves on brain neural circuitry. The goal is to define safety corridors for blast loading and develop helmets and armor to mitigate the blast threat.