Articles tagged with Diabetes
Researchers at Purdue University have developed a shoe insole that gradually releases oxygen to aid healing of diabetic foot ulcers. The insole can be customized to fit individual wound sites and is designed to improve mobility for patients with diabetes, who are at risk of losing toes or limbs if left untreated.
A study by OHSU researchers found that patients with diabetes or prediabetes in states with Medicaid expansion programs had better access to healthcare services, including preventive screenings and medication. This increase was particularly notable for patients with lower socioeconomic status.
Researchers are creating three-dimensional models of blood vessels using pig arteries and human endothelial cells to study fibroblast behavior. This could provide a powerful tool for diabetes basic research and drug screening systems.
A study published in Gerontology and Geriatric Medicine found that regular exercise among Japanese expatriates can reduce time spent sitting down and improve mental health. Compared to non-exercisers, those who exercised regularly spent 135 minutes less time sitting and had a higher quality of life score.
Researchers have developed a mouse model that closely replicates human diabetic nephropathy, revealing a key role for immune and inflammatory responses in promoting kidney damage. This finding suggests targeting these pathways may be useful for preventing or slowing the development of diabetic nephropathy.
A UK Biobank study found that certain risk factors have a greater impact on women's heart attack risk than men's. High blood pressure, smoking, and diabetes increased the risk of heart attack more in women than in men.
A study of 472,000 participants found that women with these conditions experience a higher relative risk of heart attack compared to men. The excess risk persists even in older age and could lead to an additional burden on society.
A study of over 600 patients with overweight or obesity found that a hypocaloric Mediterranean diet combined with daily exercise maintained clinically significant weight loss after one year. Patients showed improvements in glucose metabolism and inflammatory markers, while those with diabetes saw particularly high benefits.
A new study in the American Journal of Preventive Medicine reports that most US adults do not engage in muscle-strengthening exercise (MSE), with nearly 60% doing no MSE at all. The investigation found that low-to-moderate frequency of MSE is linked to fewer reported health conditions such as diabetes, obesity, and cancer.
Research reveals that diabetics' enzyme can flip blood vessel cells, creating gaps three times more permeable than normal. Controlling this process could ease swelling, nerve pain, and infection risks.
A Rutgers study suggests that extremely high blood pressure is responsible for severe organ damage due to hypertensive emergencies in African-Americans with diabetes. Better controlling blood pressure can help prevent life-threatening complications and target organ damage associated with hypertensive emergencies.
A Loyola University Chicago study reveals that diabetes causes heart failure through the accumulation of methylglyoxal, which weakens heart muscle cells. The findings suggest new drug treatments to counter the effects of methylglyoxal and prevent heart failure in diabetics.
A study by University of Pittsburgh researchers found that measuring percentage of weight regained after bariatric surgery can help predict serious health problems. The rate of weight regain was highest in the first year following maximum weight loss, indicating early detection and treatment may be crucial.
A new study published in The Lancet found that lorcaserin, an appetite-suppressant drug, decreases the risk of developing diabetes and increases the rates of remission of high blood sugar in obese and overweight patients. Lorcaserin also reduces the risk of kidney complications due to diabetes.
A nationwide study found that people with diabetes from deprived backgrounds are twice as likely to be admitted to hospital for major cardiovascular events. Socioeconomic inequalities persist, despite improvements in overall cardiovascular disease outcomes.
A new study based on SWAN data suggests that women with a history of hypertensive disorders of pregnancy and gestational diabetes may experience a greater burden of hot flashes during the menopause transition. The study identified social factors such as education as influential in shaping pregnancy outcomes and hot flashes.
Researchers found that 79% of insulin temperature logs contained deviations from the recommended range, with fridge storage being the biggest issue. This can lead to reduced potency and variability in dosing for people with diabetes, highlighting the need for proper storage and monitoring practices.
A new study found increasing infection rates for urinary tract infections, sepsis, and skin infections among people with diabetes in the USA. Rates of infection-related hospitalisations increased by 52% between 2010 and 2015 compared to the general population.
A large study in Shanghai, China found that socioeconomic development contributed to lower death rates for most diseases, likely due to lifestyle factors. Death rates from infectious diseases, maternal issues, and injuries decreased between 1974 and 2015.
Researchers found that vitamin B complex supplementation improved blood glucose regulation and kidney function in children with type-1 diabetes. The study suggests that simple supplementation may be a safe and cost-effective strategy for early protection of kidney function.
A team of researchers, led by Professor Davide Calebiro, will investigate the function of G protein coupled receptors (GPCRs) to develop new therapies for diseases like heart failure and diabetes. They will use innovative microscopy methods to directly visualize individual receptors in living cells.
The TGen-UNM consortium has been awarded a $2.8 million grant to investigate the genetic causes of diabetic retinopathy and develop precision medicine-based treatments. The study aims to identify new biomarkers and therapeutic targets to prevent the progression of the disease.
A new analysis published in The Lancet found that more than half of all countries are not on track to meet the UN target to reduce premature deaths from non-communicable diseases by a third by 2030. For women aged 30-70, only 9% of countries are on track, and for men, it's just 3%. The study highlights the need for policy changes to ad...
Researchers analyzed Twitter conversations around OpenAPS, a DIY system combining off-the-shelf CGMs and insulin pumps, to understand its benefits and limitations. The study found that OpenAPS improved self-reported A1C and glucose variability while reducing daily distress and burden, but also raised concerns about safety and regulation.
Dr. Ming-Hui Zou's research focuses on how high glucose affects mitochondria, leading to atherosclerosis and endothelial dysfunction in diabetes. The study aims to understand the cellular mechanisms behind these complications and explore potential self-defense mechanisms.
A new poll suggests that primary care providers could play a crucial role in promoting vision care for adults age 50 and older. The poll found that nearly a quarter of respondents said they hadn't had their eyes checked by an eye doctor in three years or more, citing cost and lack of insurance coverage as major barriers.
A large study found that care coordination strategies significantly reduce symptoms of depression and improve health in seniors with multiple chronic diseases. The review included 25 studies and 12,579 older adults, highlighting the potential benefits of managing co-existing chronic illnesses in a coordinated manner.
Deaths from drug overdose and suicide in the US have surpassed those from diabetes, with rates increasing by 80% between 2000 and 2016. Researchers urge national initiatives to tackle common factors behind 'self-injury', citing trauma, adversity, and mental health issues as key drivers.
A recent study published by the European Society of Cardiology found that sleeping 5 hours or less per night is associated with a doubled risk of cardiovascular disease. Men who slept five or fewer hours had twice the risk of developing a major cardiovascular event compared to those who slept seven to eight hours.
A recent study published in the New England Journal of Medicine found that fish oil supplements containing omega-3 fatty acids did not reduce the risk of cardiovascular events in patients with diabetes. The ASCEND trial involved over 15,000 participants and followed them for an average of 7.4 years.
A $5.67 million federal grant will extend and expand research into acute kidney injury, affecting 1.2 million hospitalized patients yearly, with the goal of improving prevention and treatment strategies.
A recent study found that gastric bypass surgery increases the risk of fractures, particularly in individuals without diabetes. The researchers compared data from over 38,000 patients who underwent gastric bypass operations with a control group and found a significant increase in fracture rates, with risks ranging from 26% to 32%.
Five low- and middle-income countries lack trained health workers and essential medicines, hindering readiness for noncommunicable diseases. Policymakers can engage private sector in addressing NCD burden through partnerships, medicine procurement, and service financing.
Researchers found that states expanding Medicaid eligibility in 2014-2015 saw a significant increase in diabetes medication prescriptions, with a 30% rise per 1,000 people. This growth was particularly notable for newer, more advanced forms of insulin and other medications, suggesting improved treatment outcomes.
Researchers found that diabetes medications controlling macrophage metabolism can reduce inflammation and promote wound healing. By regulating energy sources for immune cells, these medications may inhibit the progression of diseases such as obesity and diabetes.
A new study published in Diabetologia reveals that diabetes is a significant risk factor for all-site and site-specific cancers, with a higher risk in women than men. Women with diabetes have a 27% higher risk of all-site cancer compared to women without diabetes.
A team of researchers at the University of Iowa designed a web-based game called MapTrek that motivates people to get up and exercise more. The study found that participants who played the game increased their daily steps by about 2,200 per day, which is close to walking one mile.
International Conference on Engineering Biomedical Breakthroughs brings together bioengineers, diabetes researchers and scientists to share cutting-edge concepts for biomedical discovery. The conference focused on advanced biomedical imaging, bioinformatics and bioengineering tools to inform future noninvasive diagnostics.
The NYC Health and Nutrition Examination Survey (HANES) found that New Yorkers are getting heavier, with obesity rates increasing among certain groups. The survey also showed high rates of depression and sleep problems, as well as persistent racial and ethnic disparities in health outcomes.
A new diabetes diagnosis can lead to higher rates of healthy behaviors among a patient's partner, including weight management and smoking cessation. Partners with newly diagnosed diabetics exhibited greater behavioral change even when clinicians didn't focus on them.
New research from Brown University found that Medicare Advantage plan rankings may not accurately reflect the quality of care provided to disadvantaged populations. After adjusting for social risk factors, plans serving these populations improved considerably in the rankings.
A new study from the University of East Anglia found that exposure to greenspace reduces the risk of type II diabetes, cardiovascular disease, premature death, preterm birth, stress, and high blood pressure. People living close to nature also experience reduced diastolic blood pressure, heart rate, and cortisol levels.
Scientists have identified a promising plant compound, montbretin A, that inhibits pancreatic alpha-amylase activity and reduces blood glucose levels. The discovery of the biosynthetic pathway for this compound lays the groundwork for its potential use as an anti-diabetes drug.
A new study finds that air pollution contributes significantly to diabetes worldwide, with even low levels posing a health risk. The researchers estimated that pollution contributed to 3.2 million new diabetes cases globally in 2016, representing about 14% of all new cases.
A new study found Indonesia's life expectancy increased by eight years between 1990 and 2016, but non-communicable diseases have dramatically risen. The 'double burden' poses significant health challenges, with heart disease, diabetes, and injuries taking a toll on the population.
Researchers found that a fight-or-flight response can trigger the overproduction of white blood cells, leading to inflammation and increased risk of heart attacks in people with diabetes. Beta 2 blockers may help reduce this risk by limiting the proliferation of inflammatory myeloid cells.
The new guidelines emphasize the importance of involving patients with diabetes in their care plans and provide guidance on how to implement effective self-management strategies. By empowering patients to take an active role in their treatment, these guidelines aim to improve safety and outcomes for hospitalized diabetes patients.
Researchers found that combining elevated fasting glucose and HbA1c levels from a single blood sample is accurate for diagnosing diabetes. The new approach could prove useful in clinical practice by reducing patient visits and guiding treatment with HbA1c test results.
A study published in Radiology found that people who smoke or have diabetes are at increased risk of calcifications in the hippocampus, a region crucial for memory. The study suggests a link between smoking and diabetes and an increased risk of brain calcifications.
A new study suggests that medication reconciliation programs can reduce risks of diabetes patients, resulting in fewer hospitalizations and emergency room visits. The program's effectiveness was associated with improved patient outcomes and decreased healthcare costs.
Research supports thyroid screenings during early to mid-pregnancy due to increased risk of gestational diabetes and adverse health outcomes. Higher thyroid hormone levels in the first half of pregnancy are tied to development of gestational diabetes, affecting up to 2-10% of pregnancies.
Research published in Endocrine Connections found that individuals with type-1 diabetes and depression have higher galectin-3 levels, a protein involved in inflammatory immune responses. Elevated galectin-3 levels were also linked to an increased risk of inflammatory disorders such as Alzheimer's disease and cardiovascular disease.
The Endocrine Society has launched a new podcast, the Endocrine News podcast, which explores the latest advances in hormone research and clinical care. The first two episodes focus on efforts to develop a male birth control pill and the risk of novel cancer therapies triggering diabetes and other endocrine complications.
Research suggests that women who have had gestational diabetes may benefit from periodic checkups to detect early-stage kidney damage. The study found a link between high glomerular filtration rates and pre-diabetes, indicating a potential risk for chronic kidney disease.
A research team at UT Southwestern Medical Center has found that inhibiting glucose transport may be a safe and effective treatment for skin diseases like psoriasis. By targeting the metabolic requirements of hyperproliferative skin diseases, researchers were able to reduce disease-associated skin overgrowth and inflammation in mice.
Scientists have found a way to target specific gut bacteria using chemical compounds, potentially regulating diseases such as type I diabetes. The research suggests that this approach could lead to the development of drugs that permanently alter the composition of the microbiome.
A researcher at University of Houston is developing a customized motivational interviewing intervention to improve medication adherence among elderly patients with diabetes and high blood pressure. The three-year grant aims to identify barriers to adherence and develop tailored approaches to address them.
A study of nearly 6,000 Americans found that mid-life chronic inflammation may be linked to an increased risk of frailty and overall poorer health decades later. Having high levels of inflammation in middle age was associated with a 39% higher odds of frailty approximately 24 years later.
New research finds sugar replacements can cause health changes associated with diabetes and obesity, suggesting switching from regular to diet soda may not be a healthier option. Artificial sweeteners alter the body's processing of fat and energy, increasing the risk of negative health outcomes.
Diabetes impairs autophagy, a protective mechanism that filters blood waste, worsening prognosis and destroying kidneys. Researchers focus on restoring autophagy to find new therapies for acute kidney injury.