Articles tagged with Diabetes
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A recent study published by the European Society of Cardiology found that nearly 25,000 patients developed heart failure within four years of their first heart attack. The risk factors for this condition include older age, socioeconomic deprivation, and comorbidities such as diabetes.
A study found that urban neighborhoods with more walkable design have lower rates of overweight, obesity, and diabetes compared to less walkable areas. The prevalence of these conditions increased in less walkable neighborhoods between 2001 and 2012.
Adults under 40 are not being sufficiently screened for lipid abnormalities while taking antipsychotics, which increases cardiovascular risk. Improved screening of this age group is crucial for early detection and intervention.
A study published in the Journal of the American Osteopathic Association found that a common blood test can detect hidden diabetes in hospitalized patients with hyperglycemia. The HbA1C test was used to diagnose diabetes in 31 patients, and 77% had results consistent with diabetes diagnosis.
A new 20-year study shows that higher levels of cardiorespiratory fitness significantly reduce the risk of developing prediabetes or diabetes. The research found an 8-11% increase in fitness level to be associated with a 0.1% lower risk, highlighting the importance of exercise programs for reducing these conditions.
Research found a significant increase in first-time stroke hospitalizations among young Danish adults between 1994 and 2012. The study suggests lifestyle-related risk factors, such as diabetes and obesity, may contribute to this trend.
A novel intraocular therapy has been shown to prevent or reverse diabetic retinopathy in mice by increasing ACE-2 expression. The study found that the therapy reduced pro-inflammatory cells and reversed vascular degeneration, suggesting a potential new treatment for blindness and other vascular diseases.
Researchers found that increased insulin signaling reduces atherosclerosis development and improves aorta function in atherosclerosis-prone mice. The anti-atherogenic effects were linked to induction of nitric oxide and activation of downstream pathways, including endothelin receptor B (EDNRB).
A study of 295,420 infants in Bavaria found increased T1D risk associated with respiratory tract infections between 2-9 months and 3-5.9 months of age. Early exposure to viral infections may impair immune system response, suggesting a crucial first half-year of life for autoimmunity development.
A McMaster University research team is examining how environmental factors, such as agricultural practices and toxicants, affect brown adipose tissue activity in individuals with obesity or type-2 diabetes. The studies aim to develop new strategies to enhance BAT activity for treating and preventing these diseases.
The University of Texas at Austin researchers have developed an injectable, regenerative gel that delivers proteoglycans and a growth factor to stimulate the growth of blood vessels and restore blood flow in the lower limbs. The treatment has shown promising results in mice with ischemia and diabetes, with 85% recovery of blood vessels.
A new study reveals that nerve damage occurs before vessel damage in the retina due to diabetes, contradicting long-held beliefs. This finding has significant implications for treatment and prevention strategies.
Researchers have developed a non-invasive method for receptor activation using red light, which can penetrate deep tissues and activate signal pathways involved in cell division. The approach has potential for treating diseases such as cancer, Alzheimer, Parkinson, and diabetes.
A healthy diet has been found to significantly reduce the risk of high blood pressure in women with a history of pregnancy-related diabetes. Over a 22-year follow-up period, researchers discovered that women who adhered to a healthy diet were 20% less likely to develop high blood pressure.
Researchers argue that health systems need leaders who can think like designers to address complex challenges like obesity, diabetes, and cost control. Design thinking offers tools for empathy, radical collaboration, and rapid prototyping to innovate and improve healthcare.
Researchers track NADPH production through a novel pathway, revealing an environmental-dependent switch between two recognized routes. The findings have implications for diseases such as cancer and diabetes, highlighting the importance of understanding NADPH pathways in cellular processes.
Research published in Diabetologia found that people with diabetes face reduced overall life expectancy and higher numbers of years living with disability compared to those without diabetes. The study estimated a loss of 3-9 years of life expectancy and 8-9 years of disability-free life expectancy for men and women with diabetes.
Research from the University of Cambridge finds that babies of obese women with gestational diabetes are already abnormally large by 20 weeks, suggesting current screening may be too late. This could lead to lasting health impacts on the offspring, including obesity and diabetes in later life.
Research from the University of California, Irvine, reveals that controlling blood pressure, blood sugar, and LDL-cholesterol levels reduces the risk of cardiovascular disease in people with diabetes. Only 7 percent of diabetic participants met recommended levels in a major heart study.
Regular exercise can counteract health problems associated with sitting all day, according to a new study published in BMC Public Health. The research found that people who are physically active have a more desirable health profile compared to those who are inactive and spend high amounts of time sitting.
A new study published in Diabetologia found that the GLP-1 analog drug liraglutide decreases activation in the brain's cortex when individuals are shown images of desirable foods, making these foods less appealing. This suggests that liraglutide may be an effective weight loss therapy for people who tend to eat as a reward.
The study found that women have a significantly higher prevalence of peripheral artery disease, while men have a higher prevalence of carotid artery stenosis and abdominal aortic aneurysms. Diabetes is also identified as a major risk factor for developing PVD, even in patients without heart disease.
A Paleolithic-type diet improved insulin sensitivity, reduced abdominal adiposity and body weight in obese postmenopausal women. The diet high in polyunsaturated fatty acids may have long-term beneficial effects on obesity-related disorders.
Taking long naps or being excessively tired during the day is linked to a higher risk of developing metabolic syndrome, which includes high blood pressure, high cholesterol, and obesity. The study found that napping for 40 minutes or longer was associated with a significant increase in metabolic syndrome risk.
A study found that white patients and those with lower incomes were slower to discontinue diabetes medication rosiglitazone after a FDA safety alert. Patients living in higher- versus lowest-socioeconomic status communities discontinued the drug significantly earlier.
Researchers found that a poor diet and lack of exercise accelerate cellular senescence and age-related conditions in mice. Exercise was shown to prevent premature senescent cell accumulation and protect against unhealthy diet-induced damage.
Researchers at UNC and NC State create a synthetic patch filled with natural beta cells that can secrete insulin on demand, avoiding rejection risks and hypoglycemia. The 'smart cell patch' demonstrated successful blood sugar regulation in small animal models of type-1 diabetes.
Men with fertility problems are at higher risk of metabolic diseases such as osteoporosis and diabetes. Researchers found that one-third of infertile men under 50 have biochemical signs of low sex hormone levels, which can lead to fractures and increased glucose levels.
A recent study found that African Americans have a higher risk of hypertension, diabetes, and kidney failure compared to whites, even after adjusting for genetic variants. Most blacks with the high-risk APOL1 gene variant experienced similar decline in kidney function as those without the variant.
Researchers discovered that human brown fat cells show circadian fluctuations in glucose consumption, which may act as a glucose buffer and lessen the stress on the pancreas. Individuals with high brown fat abundance showed less variability in glucose levels over time.
A University of Florida study found that less than one-quarter of patients with prediabetes received treatment from their primary care physician. Prediabetes is a common condition that increases the risk of vascular problems and diabetes, yet many people remain undiagnosed or untreated.
Ultrawide field (UWF) scanning technology improved the ability to identify diabetic retinopathy in patients and judge the need for follow-up examinations or treatment. The study found that UWF imaging reduced ungradable images by 81% compared to traditional digital retinal photographs.
A study of Android diabetes apps found that 81% lacked privacy policies and 76% shared sensitive health information without consent. The apps' transmission of data to third parties poses significant privacy risks, as there are no federal legal protections against the sale or disclosure of medical app data.
A new Pacific-Rim Trade Agreement may limit access to medicines for patients with diabetes. Research suggests that Renin-Angiotensin System (RAS) blockers can have similar effects on cardiovascular and renal outcomes as other treatments.
A study of 5,644 women found that diabetes treatment decreases mammographic density, while insulin use increases it. The researchers also urge women with and without diabetes to adopt simple lifestyle changes to reduce breast cancer risk.
A new study from Ohio State University found that men and women with higher levels of linoleic acid tend to have less heart-threatening fat, more lean body mass, and lower inflammation. Higher linoleic acid levels also meant lower likelihood of insulin resistance and diabetes.
Researchers found that a cell aging program increases insulin secretion in human and mouse pancreatic beta cells, improving their function. This discovery suggests that cellular aging can bring unexpected benefits to the production of insulin, potentially leading to new insights and treatments for diabetes.
The new issue of the Annals of Global Health presents a core set of recommendations for optimizing diabetes care globally. The main findings emphasize the need for each nation to assess region-specific epidemiology, establish public health imperatives, and commit to education and research to advance culturally-sensitive guidelines.
Direct-to-consumer genetic testing raises concerns about physicians' preparedness to discuss test results and potential downstream effects on the healthcare system. A study found that only a minority of consumers share their results with their doctor, often due to physician's inability to answer questions and address patient concerns.
Scientists at the University of Michigan have developed a novel method to observe insulin production in the pancreas of living animals. The technique allows researchers to see how much insulin is present and respond to sugar levels in real-time, revealing surprising insights into pancreatic function.
Researchers found that diseased exocrine tissue can cause deficiencies in endocrine cells, leading to diabetes. The discovery suggests a new target for stem cell-based treatments.
A new study published in Nutrition and Diabetes journal found that low-carbohydrate, high-fat diets can lead to rapid weight gain and worsen glucose intolerance. The research suggests that fad diets like Paleo may not be suitable for people with pre-diabetes or diabetes.
A new study published in Breastfeeding Medicine found a significant association between diabetes during pregnancy and low milk supply. Women with maternal glucose intolerance were more likely to experience lactation difficulties, highlighting the need for targeted therapies to support breastfeeding mothers.
Scientists discover that activating mTOR pathway plays a critical role in beiging of white fat cells to fight diabetes. Rapamycin, a drug previously used as an immunosuppressant, is found to induce beige fat cell formation and improve glucose metabolism.
Red raspberries contain essential nutrients like vitamin C and fiber, which may help reduce the risk of metabolically-based chronic diseases. The polyphenolic components in red raspberries have been shown to reduce oxidative stress and inflammation, making them a promising food for heart health and brain function.
A new study finds that only 9% of weight loss programs adhere to expert medical guidelines, leaving consumers unclear about their regimen. The majority of programs lack essential components like high-intensity interventions and moderate physical activity.
Researchers aim to optimize synthetic ERRγ activators for potency and selectivity to advance treatments for various diseases. Previous studies in animal models suggest increased expression of ERRγ improves exercise capacity and mitochondrial function.
Researchers found that blacks, Latinos and Asians had lower risk of coronary heart disease compared to whites without diabetes or prior history of heart disease. The study suggests systematic efforts by Kaiser Permanente may help reduce racial disparities in health care.
A study by Finnish researchers found that removing a gene from mice protected them against arterial disease and obesity, due to increased activity of brown adipose tissue. The discovery suggests that inhibiting the USF1 gene might be a good strategy for treating cardiovascular disease and diabetes.
Researchers at Dresden University Hospital have discovered a molecular signal pathway that allows stem cells and pancreatic islet cells to interpret signals in a similar manner. This finding could lead to new approaches for regenerating damaged tissue and treating metabolic diseases such as diabetes.
Researchers found that older adults with diabetes who received structured depression care management were 53% less likely to die compared to those receiving usual care. This treatment also improved depression symptoms more effectively.
A study found that two consecutive nights of extended sleep can counteract the increased risk of diabetes associated with short-term sleep restriction during the work week. Insulin sensitivity and diabetes risk returned to normal after two nights of extended sleep.
A study published in The BMJ found that higher potato consumption before pregnancy increases the risk of gestational diabetes. Swapping potatoes for other vegetables, legumes, or whole grains may lower this risk, possibly due to their lower glycaemic index.
Adults with severe obesity who spend more time sitting are at higher risk of cardiovascular and metabolic diseases. Replacing sedentary behavior with low-intensity physical activities may improve cardiometabolic health.
A large new study found previously unknown risk factors associated with keratoconus, a condition that causes progressive nearsightedness at a young age. The study revealed higher odds of developing keratoconus among men, African Americans, Latinos, and those with asthma and sleep apnea.
Researchers at the Gladstone Institutes have successfully converted human skin cells into fully-functional insulin-producing pancreatic cells. These new cells protected mice from developing diabetes in a mouse model of the disease, offering a promising approach to personalized cell therapy for patients with diabetes.
A new study published in the American Journal of Obstetrics and Gynecology found that metformin decreases the production of toxins elevated in preeclampsia and helps heal injured blood vessels. The drug is considered safe during pregnancy, offering a potential new treatment option for women with preeclampsia.
Professor Ian Craddock discusses how IoT technologies can transform health care and reduce costs by managing chronic conditions outside the hospital environment. He will explore challenges, security concerns, and application scenarios for healthcare using his SPHERE project as an example.
A Massachusetts General Hospital study found that unmet socioeconomic needs, such as difficulty affording food or transportation, are directly related to poor health outcomes. Patients with unmet needs were more likely to have chronic conditions like diabetes and hypertension.
A Stanford study found that infertile men have a higher risk of developing heart disease, diabetes, and other health problems. The research suggests that male infertility is associated with increased rates of mortality and general health issues, even after adjusting for obesity and smoking.