Articles tagged with Diabetes
A new study led by Harvard T.H. Chan School of Public Health found that consuming propionate may trigger a cascade of metabolic events leading to insulin resistance and hyperinsulinemia. The research also showed that mice exposed to chronic propionate resulted in weight gain and insulin resistance.
A multinational study led by Vanderbilt University researchers has found that diabetes has reached epidemic proportions in Asia, dramatically increasing the risk of premature death, especially among women and middle-aged people. The study highlights the urgent need for tailored diabetes management programs for Asian populations.
The project aims to integrate diabetes and hypertension services with HIV-infection services to test their efficacy and applicability. Chronic conditions are expected to overtake infectious diseases in sub-Saharan Africa within the next decade.
A study published in Experimental Physiology found that shift work can have a long-term effect on the risk of heart disease and diabetes. Shift work was shown to negatively impact the breakdown of triglycerides and sugar utilization in the body, increasing the risk of these diseases.
A meta-analysis found that liquid meal replacements led to an average of five pounds more weight loss compared to conventional low-calorie diets. Additionally, these liquid meal replacements contributed to better reductions in body mass index and systolic blood pressure.
Researchers have shown that gene transfer therapy can improve left ventricle function and glucose disposal in mice with diabetes. A single injection of a hormone called urocortin 2 increased heart function and reduced blood sugar levels, offering a potential new treatment for cardiovascular disease.
Research presented at ENDO 2019 found that walking downhill after eating reduces bone resorption in postmenopausal women with diabetes. The study suggests combining exercise after meals with downhill walking may help reduce the need for osteoporosis medication.
A nationwide survey of Brazilian teens found that excessive screen time and unhealthy snacking are associated with an increased risk of metabolic syndrome, a cluster of risk factors for heart disease and diabetes. The study suggests that limiting screen time and avoiding snacks in front of screens may help reduce this risk.
The Endocrine Society's Clinical Practice Guideline recommends simplifying medication regimens and tailoring glycemic targets to improve compliance and prevent complications in older adults with diabetes. The guideline prioritizes blood glucose targets over hemoglobin A1c tests, aiming to reduce cardiovascular disease outcomes.
A study found that people with diabetes are at a higher risk of fractures, particularly among Caucasians and Hispanics. However, African Americans with diabetes showed little to no increased fracture risk compared to those without diabetes.
Women with undiagnosed gestational diabetes are at a significantly increased risk of stillbirth, according to new research. The study found that the risk of stillbirth was over four times higher in women who developed signs of gestational diabetes but were not diagnosed, highlighting the importance of proper screening and diagnosis.
A pilot study reveals that over a third of middle school kids had abnormal blood sugar or cholesterol levels. Two students were found to have diabetes, highlighting the need for routine screening in this age group.
Patients with insulin-dependent diabetes are more than five times as likely to experience post-operative hyperglycemia compared to those without the condition. The risk is linked to higher blood glucose levels over the previous three months, regardless of insulin dependency.
Elevated soothability in infants was associated with increased likelihood of early childhood obesity and shorter breastfeeding duration. Infant temperaments of elevated soothability and activity also linked to early introduction of sugary drinks, contributing to obesity risk.
A study has revealed that young adults under 40 are experiencing an alarming increase in heart attacks, despite having the same mortality rates as older survivors. Substance abuse and diabetes may be contributing to this trend, emphasizing the need for prevention and early detection of cardiovascular disease.
A new study suggests that glucagon can help regulate insulin action and prevent blood sugar levels from becoming too high. By activating a protein called PGC1A, glucagon can prepare the liver to respond quickly to insulin signals after meals.
A pilot study found that remote blood pressure monitoring via smartphone app, accompanied by education and health coaching, can significantly improve blood pressure control. Participants who had the highest blood pressure at baseline showed the most reductions in both systolic and diastolic pressure.
Preliminary research found that adding high-quality plant-based foods to a diet decreases the risk of deaths from heart disease. A 10-point increase in score on a healthy plant-based diet scale was associated with a 10% lower risk of cardiovascular disease death.
Researchers found quitting smoking significantly outweighs the risk of gaining weight for people with diabetes, despite potential weight gain being a risk factor for cardiovascular disease. The benefits of quitting smoking are substantial, with cardiovascular disease risk reduced by up to 41% among long-term quitters.
A new study reveals that diabetes impairs the antibacterial activity of multipotent stromal cells (MSCs), leading to diminished capacity to fight off bacterial infections. This finding has significant implications for the use of MSCs as a therapeutic strategy in treating diabetes and other autoimmune disorders.
UC San Diego Health, Ochsner Health System, Sutter Health and Stanford Health Care developed diverse models of care incorporating patient-centered technologies with measurable outcomes. Technology improved medication adherence for hypertension and diabetes, reduced distress in cancer patients, and enhanced patient engagement.
Children's Hospital Los Angeles has been awarded a grant to adapt a patient-driven model of care that increases treatment compliance among difficult-to-reach populations, particularly adolescents with diabetes. The goal is to improve the quality of life and manage diabetes effectively in young adults.
A new study from UC Berkeley finds that a soda tax led to a significant decrease in sugary drink consumption, with water consumption also increasing. The results suggest that taxes may be an effective tool in reducing sugar-linked diseases like diabetes and cardiovascular disease.
A new study from Kanazawa University found that dietary n-6 fatty acid intake influences hypertension risk differently in healthy individuals and those with diabetes. In healthy subjects, high n-6 fatty acid intake is associated with increased hypertension risk, while in patients with diabetes, it may lower blood pressure.
A study of over 30,000 Americans reveals significant differences in managing heart disease risk between women and men. Women have better control of high blood pressure, while both sexes struggle with obesity and cholesterol management.
Diabetes mellitus increases risk of stable ischemic heart disease, with trial data showing no benefit from nuclear stress tests or cardiac computed tomography. Revascularization for SIHD also does not reduce mortality or myocardial infarction rates in diabetic patients without symptoms.
This special issue of Cardiovascular Innovations and Applications Journal covers key aspects of stable ischemic heart disease, including contemporary management strategies and epidemiology. The collection of reviews and commentary provides insights into the latest research and clinical practices for this condition.
Researchers from Mount Sinai will investigate the role of follicle-stimulating hormone (FSH) in regulating bone mass, body composition, and fat deposits during aging and menopause. The program aims to develop an FSH-blocking antibody for preventing and treating osteoporosis and obesity.
Researchers at University of Toledo have developed a mouse model that spontaneously develops type I diabetes and its complications, allowing for study of disease progression. The breakthrough has the potential to reshape how type I diabetes is studied and may lead to new treatments or a cure.
A study of 959 obese pregnant women found no significant difference in birth outcomes between early and routine gestational diabetes screening. Early screening was associated with increased insulin use, a potential drawback for patients.
A study analyzing electronic health records found that Native Americans experience a higher incidence of ischemic stroke, with common risk factors including high blood pressure, diabetes, and smoking. The study also revealed significant increases in these modifiable risk factors between 2000 and 2016.
A study published in the Journal of Obesity found that losing weight quickly versus slowly does not provide additional health benefits, with improvements in metabolic health being similar regardless of rate. The focus should be on achieving sustained weight loss at a safe pace of one to two pounds per week.
The University of Illinois Chicago will continue its role as the Chicago field center for the Hispanic Community Health Study/Study of Latinos, a multi-site study of health issues and risk factors among Hispanic/Latino adults. The new funding will support phase III of the study, which aims to bring back participants for a follow-up exa...
Geriatric frequent users are more likely to have multiple chronic conditions and require more resources and medical interventions. The most common conditions among these patients include diabetes, kidney disease, and congestive heart failure.
Researchers have pinpointed a mechanism that leads to steroid diabetes in patients undergoing long-term cortisone treatment. The findings suggest that the E47 transcription factor plays a key role in the changes in gene expression, particularly in liver cells.
The interoperable Artificial Pancreas System smartphone app has shown improved time in the target glucose range and a statistically significant reduction in time below 70mg/dL. The study suggests that this system could provide personalized care for patients with diabetes, offering flexibility and convenience.
A recent study found that insulin deprivation in mice resulted in decreased ATP production in brain regions critical for memory, similar to previous findings in skeletal muscle. Intranasal insulin treatment reversed this decline, suggesting insulin's role in maintaining brain mitochondrial function.
A new study finds that people with pre-diabetic blood sugar levels are at a lower risk for developing cardiovascular disease. However, most individuals will go on to develop diabetes unless they take measures to reduce their blood sugar levels.
A study published by The Endocrine Society found that gastric bypass surgery improves relative muscle strength and physical performance in people with obesity. Despite dramatic weight loss causing a decline in absolute strength, patients experience meaningful improvements in walking speed and other measures of physical function.
Researchers at the University of Copenhagen's Niels Bohr Institute have found a new mechanism in bodily cell regulation through chaos. Chaotic swings in a protein's concentration activate genes, optimally tuning the immune system.
A new Ohio State University study found that adhering to heart health guidelines can lower the risk of developing diabetes by 70% over 10 years. Researchers analyzed data from 7,758 participants and discovered that those with normal blood glucose levels who met four or more guideline factors had a significant reduction in diabetes risk.
Researchers have developed a breakthrough technology to grow human blood vessels as organoids in a petri dish, which can be used to study vascular diseases and identify potential treatments. The discovery has the potential to unravel causes of conditions such as Alzheimer's disease, cardiovascular diseases, and cancer.
A recent study by researchers at The Ohio State University Wexner Medical Center found that following heart health guidelines can significantly reduce the risk of developing diabetes. Participants who met the recommended ranges for four or more of the seven factors had a 70% lower risk of developing diabetes over the next 10 years.
Scientists at the University of Bergen found that glucagon-producing cells in the pancreas can change identity and adapt to produce insulin for damaged or missing cells. This discovery may lead to new treatments where the body produces its own insulin with minimal assistance.
Researchers found that participants who completed mindfulness training lost an average of 3 kilograms more than those who did not attend the course. The study suggests that mindfulness techniques can help improve eating behavior and facilitate successful weight loss in individuals with obesity.
Research suggests that a novel protein called Nischarin may be a promising therapeutic target for obesity and diabetes. Studies found that Nischarin expression is suppressed in fat tissue of obese humans and that its disruption leads to insulin resistance in female mice, but not male mice.
Researchers explore protein tyrosine phosphatases in metabolic diseases to understand diabetes development. They focus on inflammation's role in pancreas and liver cells, aiming to identify new therapeutic approaches targeting PTPs.
A Swedish study found that the risk of heart attack peaks at around 10 pm on Christmas Eve, especially for older and sicker individuals due to heightened emotional stress. This risk is also higher during New Year's and Midsummer holidays, as well as Monday mornings.
Researchers found a novel time-keeping mechanism within liver cells that contributes to disease development when its natural rhythm is disrupted. The study suggests that the circadian clock modulates HNF4A's classical functions, providing a potential explanation for diseases such as diabetes and cancers.
A study published in Palgrave Communications found a strong negative correlation between median household income and obesity rates in the US. Since 1990, the rise of obesity has been fastest among the poorest regions, with lower-income households facing a higher likelihood of suffering from obesity and diabetes.
A study published in Nutrition and Diabetes found that four dried fruits - dates, apricots, raisins, and sultanas - have a lower glycemic index than white bread. The results suggest that dried fruits can be used as a low glycemic index food source to replace higher glycemic index foods.
Patients with diabetes are more likely to experience hypoglycemia after fasting, which can lead to faintness, confusion, and loss of consciousness. The study suggests that routine fasting guidelines may not be necessary anymore, and proper education about fasting and diabetes is lacking.
A new study by American Society of Nephrology examined 281,233 patients with diabetes and CKD in 130 VA facilities. The findings point to areas where care might be improved and standardized among facilities.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism reveals weight cycling is associated with a higher risk of death. Conversely, weight loss from weight cycling can reduce diabetes risk in people with obesity.
A recent study found that high blood pressure affects around 19% of Indian adults, with diabetes being a major risk factor. Screening for hypertension should start at age 18-19 and include education on healthy lifestyles to prevent the condition.
A new study suggests that regular vitamin B12 screening in metformin-treated type-2 diabetes patients can reduce the risk of irreversible nerve damage. The study found that nearly 70% of patients were not being checked for vitamin B12 levels, despite a link to peripheral nerve damage.
A new study suggests that antioxidants can reduce cognitive impairments caused by low blood sugar in diabetic patients. The research found that stimulating antioxidant defenses with sulforaphane improved cognitive ability in mice, indicating potential benefits for humans.
Researchers identified a gene mutation in SGLT1 that helps protect against spikes in glucose levels, resulting in lower incidence of obesity, diabetes, death, and heart failure. The study's findings suggest potential therapeutic targets for metabolic disease.
Physicians say firearms are within their lane, disagreeing with NRA's stance on gun violence prevention. The American College of Physicians is collaborating with the American Foundation for Firearm Injury Reduction in Medicine to provide funding for research and develop practice recommendations on firearm injury prevention.
Research found that individuals with diabetes who switched to high-deductible health plans experienced delays in seeking care for symptoms of blood vessel diseases, including cardiac chest pain and transient ischemic attacks. The study suggests that increased out-of-pocket costs lead to changes in healthcare behavior.