Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A new study has found that high blood glucose levels before pregnancy can increase the risk of severe maternal morbidity and death, even in women without diabetes. The study analyzed data from over 31,000 women and found that elevated hemoglobin A1c levels were associated with a higher risk of adverse outcomes
A large international study found that consuming at least two daily servings of dairy products is associated with lower risks of diabetes and high blood pressure. Full-fat dairy products showed the strongest associations, particularly in countries with low dairy intakes.
Researchers found that virtual care did not negatively impact glycemic outcomes for diabetes patients, improving hospital exposure and transmission risk. The study's results have broader implications for telehealth implementation in remote locations.
Researchers surveyed patients with diabetes on their understanding of sharing medical data, finding they prefer a digital consent application that offers empowerment and control. The Dovetail Digital consent application, using blockchain infrastructure, received favorable responses for its transparency and traceability.
Researchers at Joslin Diabetes Center have discovered two subtypes of human white subcutaneous fat cells with distinct patterns of gene expression, which may help control whether cells become mature fat cells. This study highlights the potential of bringing together biology, artificial intelligence, and data analysis to better understa...
Researchers at Salk Institute discover two genes that regulate levels of healthy fats called FAHFAs, which decrease inflammation and increase insulin sensitivity. An experimental drug successfully increases FAHFA levels by blocking the activity of these genes, offering new insights into therapies for metabolic and inflammatory diseases.
Research highlights age-related muscle loss as a contributing factor to diabetes in the elderly. Men with lower lean body mass are more prone to developing diabetes, but not women.
A study by Korean researchers found that breastfeeding lowers maternal postpartum diabetes incidence and improves metabolic health through serotonin production. The research showed sustained improvements in pancreatic beta cells lasting years after lactation cessation, reducing the risk of developing diabetes.
The North Carolina Diabetes Research Center will provide educational programs, pilot grants, and research infrastructure support to investigators in diabetes research. As one of only 12 NIH Diabetes Research Centers, the grant aims to connect investigators with collaborators to expand project scope.
Researchers at Pohang University of Science & Technology developed smart contact lenses that can detect diabetes and treat diabetic retinopathy by controlling insulin secretion with electrical signals. The lenses verified accurate glucose level detection in tears of diabetic rabbits.
Researchers from DZD and Boston Children's Hospital highlight the importance of body weight and metabolic health in understanding COVID-19 severity. Studies suggest that obesity may increase the risk of severe illness, independent of cardiometabolic diseases.
Research team finds that high-altitude adaptations in the Himalayas may lower risk for hypertension and diabetes-associated anemia. The study, led by Katherine Wander of Binghamton University, found that a Tibetan-descended population living in Southwest China had lower rates of these conditions compared to low-altitude Han populations.
A new study from Aarhus University shows that a motivational interview with a GP can have a preventative effect on cardiovascular disease. The study found a 13% reduction in cardiovascular disease risk among patients without diabetes who talked to a GP trained in motivational interviewing.
Understanding interactions between metal ions and peptides may lead to improved treatments for diabetes, Alzheimer's, and other diseases. Researchers found that copper can impede the aggregation of pramlintide, but not rat amylin.
Researchers at Houston Methodist have developed a fatty acid-based platform for biological drug delivery, demonstrating high absorption rates in mice models. The study published in Science Advances may pave the way for oral delivery of more biological drugs, including those used to treat rheumatoid arthritis and autoimmune diseases.
Individuals taking glucocorticoid medications for conditions like asthma and arthritis are at high risk of severe COVID-19 due to suppressed immune systems. Injectable supplemental therapy can reverse adrenal failure and is crucial in managing patients with primary or secondary adrenal insufficiency.
Researchers used machine learning to analyze nationwide health checkup records and identified a reliable method for predicting diabetes patients. The model accurately predicted future incidence of diabetes with an overall accuracy of 94.9%.
A recent study suggests that bariatric surgery performed before developing diabetes results in greater weight loss. Patients without diabetes achieved a higher chance of successful weight loss compared to those with diabetes, with diabetes diminishing weight loss by 1.2 BMI points.
Researchers from Kumamoto University found that Melinjo seed extract activates the beneficial hormone adiponectin, improving obesity and diabetes. The study discovered individual genotype differences affect efficacy.
A study by Singapore researchers found that underweight diabetics have an eight-fold increase in risk of contracting active TB compared to obese individuals. The study highlights the importance of early diagnosis and targeted screening for this vulnerable population.
Researchers developed a mathematical model to predict the behavior of glucose-responsive insulins in humans and rodents. The model identified optimal designs that could work well in both species, with about 13% predicted to be effective in both, and 14% in humans alone.
A new study from the Joslin Diabetes Center reveals that ultra-wide field (UWF) fluorescein angiography detects over three times more microaneurysms than UWF color imaging, highlighting the need for cautious use of these techniques when evaluating and treating diabetic retinopathy. The research also suggests that AI can automate the gr...
Research suggests that middle-aged individuals who walk the most steps per day have a significantly lower risk of developing diabetes and high blood pressure. Women in particular see a substantial reduction in obesity risk, with the highest step count linked to a 61% lower likelihood.
A new Yale study suggests that consuming low-calorie sweeteners with carbohydrates impairs metabolism. The research challenges the 'uncoupling hypothesis' and instead finds that sucralose can cause problematic metabolic responses when paired with carbs.
A study found that older adults who experience excessive daytime sleepiness are at increased risk of developing diabetes, cancer, and heart disease. Researchers analyzed data from over 10,000 participants and discovered a significant link between daytime sleepiness and the development of these conditions.
A new technology developed at Purdue University has shown promise in treating obesity and diabetes by converting bad fat into good fat. The Adipo Therapeutics team is seeking additional funding to further develop their technology and submit it to the FDA.
A study found that people become less confident in their choices when faced with new information related to familiar topics like finances and health, suggesting a critical gap in understanding how new information interacts with prior knowledge. This highlights the need for tailored information based on individual mental models.
Researchers have discovered a new drug combination that can restore beta cell function in an animal model, showing promise for diabetes remission. The treatment, which combines GLP-1/estrogen with insulin, was found to be more effective than single-treatments and increase pancreatic insulin content and beta cell numbers.
A Kaiser Permanente study found that diabetes patients who used the patient portal and mobile phone app showed significant improvements in health outcomes. The use of these online tools was associated with increased medication adherence and lower blood glucose levels, particularly among patients with higher baseline HbA1c levels.
Researchers found that morning versus evening dosing of warfarin has insignificant effect on anticoagulant stability, suggesting patients can take medication at any regular time. A separate study showed that home blood pressure monitoring in cases of clinical uncertainty can improve hypertension control and patient understanding.
A peer-delivered program incorporating cognitive behavioral approaches improved health outcomes in rural adults with diabetes. Participants showed significant improvements in functional status, pain, and quality of life compared to a control group.
A systematic review and meta-analysis found significant reductions in body mass index (BMI), body weight, waist circumference, and fat mass in children and adolescents treated with metformin. However, the treatment did not affect lean body mass or have a significant impact on those who were already overweight or obese.
Research found certified medical home practices had better performance outcomes on diabetes care quality measures and more systems compared to non-certified practices. Certified practices also showed slightly better performance on diabetes care quality measures despite having similar patient populations as non-certified practices.
Researchers followed patients with diabetes who developed diabetic retinopathy and found a 60% higher risk of stroke among those with damaged eye vessels. Patients with diabetic retinopathy should receive aggressive medical management to reduce stroke risk.
A recent study found that diabetes prevalence is higher among First Nations people and women, particularly those of reproductive age. The gap has narrowed over time, but the risk factors persist. Understanding these determinants is crucial for effective prevention and management strategies.
A recent study found a strong association between the incarceration of a family member during childhood and an increased risk of developing diabetes in men. The study, conducted by researchers from the University of Toronto and University of Alabama, analyzed data from over 40,000 adults and found that men who experienced childhood inc...
A team of Yale researchers has discovered a way to reverse type-2 diabetes and liver fibrosis in mice, highlighting the potential for targeting TET3 protein. The studies, published in Cell Reports and Nature Communications, also suggest that TET3 plays a role in fibrosis development and may be a key target for treatment.
A new study found that Medicaid expansion significantly reduced uninsured rates among low-income residents in the Diabetes Belt. The increase in insurance coverage helped address access to care issues, leading to improved health outcomes and quality of life for those affected by diabetes.
A new study by the University of Alberta found that pregnant women with elevated fasting blood sugar levels are at a higher risk of complications, including large babies, high blood pressure, and preterm births. Despite receiving diabetes drug treatments, these women were more likely to experience adverse outcomes.
A WVU project uses the Intelligent Retinal Imaging System to detect diabetic retinopathy in West Virginians, reducing risk of severe vision loss by 90%. Over 5,400 patients have been screened, with 21% showing evidence of retinopathy.
Researchers found that barbershop screenings can effectively identify undiagnosed black men with diabetes. The initiative is part of efforts to address significant racial disparities in healthcare access and outcomes.
A new longitudinal study shows a link between multiple metabolic disorders in mothers during pregnancy and children's body mass indexes later in life. The study found that when a mother experiences both gestational diabetes and preeclampsia, the child has an increased risk of high childhood BMI over time.
A 16-year study of Hong Kong's population found that death rates from all-cause mortality, cardiovascular disease, and cancer decreased significantly in older adults with diabetes. In contrast, younger adults with diabetes experienced little to no change in their death rates over the same period. The researchers suggest that targeted p...
A new computer algorithm can predict in early pregnancy or before pregnancy which women are at high risk of gestational diabetes. The study analyzed data on nearly 600,000 pregnancies and identified nine parameters that accurately predicted the risk of developing gestational diabetes.
A new study by researchers from Boston University School of Public Health and Chulalongkorn Universities identified strengths and weaknesses in Thailand's diabetes care. The majority of Thai adults with diabetes were never diagnosed, but most who were diagnosed received treatment and controlled their condition.
Researchers at Stockholm University discovered engineered silica particles can reduce food efficiency, leading to lower weight gain and improved metabolic profiles in mice. The study suggests these particles could be used to treat obesity and diabetes in humans.
Researchers developed a smart photonic contact lens that measures glucose concentration in conjunctival blood vessels, enabling diabetic diagnosis. The device also shows promise for treating diabetic retinopathy by reducing angiogenesis and verifying clinical feasibility.
Scientists have developed a non-fibrillating form of human insulin called glycoinsulin, which demonstrates the same glucose-lowering effects as native insulin without fibril formation. This discovery presents a promising solution for patients relying on insulin pumps and could improve the shelf life of insulin products.
A population study found that diabetes is an independent risk factor for heart failure, with 21% of diabetic patients developing heart failure over a 10-year period. This study supports the concept of diabetic cardiomyopathy and highlights the need for further research into this association.
Researchers at Helmholtz Munich have created a technique called Mid-infraRed Optoacoustic Microscopy (MiROM) that provides real-time images of biomolecules in living cells without the need for labels or contrast agents. This method offers novel insights into metabolic processes and can be used to study the effects of different diets on...
This observational study found that the age-sex-adjusted proportion of US adults with diabetes was 12.1% for non-Hispanic whites, 20.4% for non-Hispanic blacks, 22.1% for Hispanics, and 19.1% for non-Hispanic Asians. Notably, Hispanic and non-Hispanic Asian subpopulations showed significant differences in undiagnosed diabetes rates.
A genetic risk score can identify individuals at a 3-fold increased risk of developing ischaemic stroke, a devastating condition. This scoring system may require more intensive preventive measures than current guidelines recommend.
A new national study found that walking and cycling to work were associated with a significant reduction in heart attacks. For women who walked to work, there was an associated 1.7% reduction in heart attacks the following year, while men who cycled to work experienced the same decrease.
The global diabetes epidemic is reaching epidemic levels, with 425 million people affected and projected to increase to over 600 million. The book 'Traveling with Sugar' examines the havoc diabetes has caused in Belize, highlighting the need for improved infrastructure for treating the condition.
A team of researchers at Wayne State University is developing a novel oral insulin delivery system to address the issues of low absorption and bioavailability. The goal is to create a safe and efficient treatment that can enhance the quality of life for diabetes patients.
Researchers discovered a connection between gastric bypass surgery and the release of glucagon-like peptide-1 (GLP-1), a hormone regulating appetite. The study found that mHMGCS, an enzyme triggering ketone body formation in the small intestine, inhibits GLP-1 release.
A new UBC study finds that many Canadians live with multiple chronic health conditions, including cardiometabolic diseases like stroke, heart disease, and diabetes. Lifestyle behaviors such as physical inactivity, poor diet, and high stress levels are associated with a higher risk of developing these conditions.
A Hebrew University study found pregnant women who smoke are nearly 50% more likely to develop gestational diabetes. Women who cut down on their cigarette intake still face a 22% higher risk compared to non-smokers or those who quit before pregnancy.
A study by University of Utah Health found that people with chronic illnesses turn to underground exchanges for medicines and supplies due to affordability and accessibility issues. Many participants donated or traded goods with family, friends, or strangers who couldn't get them through traditional channels.
Rates of cardiac events such as heart failure and myocardial infarction decreased up to 60% among First Nations people with diabetes in Ontario. However, hospitalizations and deaths remained more frequent compared to non-First Nations individuals.