Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
A recent study published in JAMA Internal Medicine investigated the association between cycling and mortality rates among individuals with diabetes. The research suggests that regular cycling may help reduce the risk of death from cardiovascular disease or any other cause.
A new study found that body mass index (BMI) is a risk factor for diabetes, but the optimal BMI threshold for screening varies significantly across low- and middle-income countries. The researchers analyzed data from over 680,000 people in 57 countries and found that individuals with a BMI of 23 kg/m2 or greater had an increased risk o...
Research suggests that antidepressant treatment can improve outcomes for individuals with comorbid diabetes and depression, reducing the risk of serious complications such as heart disease. Regular adherence to antidepressants is associated with better diabetes management and quality of life.
A new AI tool automatically measures fat around the heart from MRI scan images, linking it to increased diabetes risk. The tool was tested on over 45,000 people and accurately calculated their risk of developing diabetes.
Recent guidelines discourage routine aspirin use in adults 70 and older, but research suggests that older adults with diabetes may have potential overuse of aspirin therapy. If not actively discontinued, this could lead to unnecessary risks and side effects.
Researchers at Staffordshire University have developed a novel, low-cost method to detect foot ulcer risk without electronic sensors. This new technique uses 3D-printed structures to identify areas with high pressure, enabling clinicians to prescribe custom footwear or insoles.
Research reveals that people with frequent sleep problems are at a higher risk of dying than those without sleep problems. Specifically, individuals with Type-2 diabetes who also experience sleep disturbances face an increased mortality rate of 87%.
Only 5% of men and 9% of women meet daily fiber recommendations, associated with higher risks of heart disease and diabetes. Higher dietary fiber intake is strongly linked to reduced markers for heart and kidney disease in adults with diabetes.
Researchers investigated the effect of real-time continuous glucose monitoring on glycemic control among patients with insulin-treated diabetes. The study found that this technology improved blood sugar control, allowing for more effective management of the condition.
A healthy diet before and during pregnancy may reduce risks of gestational diabetes, high blood pressure disorders, and preterm birth. Women who followed healthier eating patterns had lower risks for these pregnancy complications.
A study by CNIC scientists found that glycosylated hemoglobin can identify individuals with advanced atherosclerotic disease and increased cardiovascular risk. The test can be used to calculate the degree of subclinical atherosclerosis in the general population, enabling personalized treatment plans.
A new study aims to identify diabetic donors whose corneas are suitable for transplant surgery, a crucial step in addressing growing demand for the procedure. The Diabetes Endothelial Keratoplasty Study will explore the impact of donor and recipient diabetes on outcomes and inform eye-banking and surgical practices.
A 23-year study found strong links between gestational diabetes during pregnancy and the development of type-1 and type-2 diabetes later in life. Women who experienced gestational diabetes were more prone to developing these conditions, highlighting the importance of autoantibody testing for risk assessment.
A global study found that nearly half a billion people with diabetes are not receiving comprehensive care, which can reduce health risks such as heart attacks, strokes, and nerve damage. The study highlights major gaps in specific care, including low cholesterol-lowering medication use.
A study suggests that pregnant women with gestational diabetes made only modest dietary changes, including a reduction in juice consumption and an increase in artificially sweetened beverages. Disparities were found in certain groups, such as Hispanic women and those with obesity or lower education levels.
Researchers found that sotagliflozin reduced the risk of death or worsening heart failure by 22-43% in patients with both diabetes and heart failure. The medication showed significant benefits across various patient subgroups, including those with preserved ejection fraction.
A University of Cincinnati researcher has found that plasma proteins discovered in the blood samples of diabetic patients who developed obstructive coronary disease may serve as biomarkers of severe heart blockage. This discovery could help patients with diabetes identify their risk and receive timely medical attention.
Researchers at UCSF have found a way to stimulate the natural surveillance system of immune cells to eliminate senescent cells, which contribute to aging and chronic diseases. This discovery offers an alternative to existing senolytic therapies and may lead to new treatments for age-related chronic diseases.
A systematic review of studies on telehealth and chronic conditions found that frequent services benefited patients more when continued for about a year. However, the optimal frequency and duration of telehealth services remain unknown. Researchers are working to measure dose in standard ways to inform best practices.
Researchers have developed a personalized sweat sensor that accurately estimates blood glucose levels without the need for finger pricks. The device uses a polyvinyl alcohol hydrogel and electrochemical sensors to measure glucose in sweat, providing an accurate estimate of blood sugar levels with an accuracy rate of over 95%.
A large clinical trial has definitively shown that dexamethasone, a steroid commonly used during anaesthesia before surgery, does not increase the risk of surgical wound infections. The study enrolled over 8,700 patients and found no significant difference in wound infection rates between those receiving dexamethasone and placebo.
A new study has identified risk factors for a severe course of COVID-19 in people with diabetes, including male sex, older age, high blood glucose levels, and existing comorbidities. Chronic metformin treatment was found to be associated with a reduced risk of severe COVID-19.
Researchers have discovered a compound found in some vegetables that may help reverse kidney problems associated with diabetes. Phenethyl isothiocyanate (PEITC) has been shown to target multiple pathways involved in diabetic nephropathy, including inflammation and oxidative status.
Researchers discovered that annual foot assessments can detect atrial fibrillation in patients with diabetes. The condition is found in approximately 17% of patients with diabetes, increasing stroke risk by five times.
A study found that addressing social determinants of health improved blood pressure control in patients with diabetes or hypertension in Kenya. The intervention combined community microfinance groups with group medical visits reduced systolic blood pressure by 44% compared to standard care.
Researchers are conducting a five-year longitudinal study to assess the non-pulmonary aspects of cystic fibrosis and identify barriers to healthy habits. The study aims to generate information on which patients are most likely to develop type 2 diabetes and how diet and exercise can reduce the risk.
A large study found that nearly 30% of patients with coronary artery disease have diabetes, significantly higher than the general population. Patients with heart disease and diabetes had worse outcomes, including a 38% higher risk of death during a five-year follow-up.
Researchers at The University of Tokyo have developed a novel cell therapy using a lotus-root-shaped device to transplant human pancreatic beta-cells in the long term. The device, called LENCON, was shown to successfully control blood glucose levels for over 180 days in diabetic mice.
Researchers found associations between lifestyle factors and COVID-19 infection risk, including maintaining healthy weight and high HDL cholesterol levels. These factors may help lower the risk of COVID-19 infection.
Researchers found persistent racial disparities in diabetes and high blood pressure-related mortality in rural areas, despite improvements in urban areas. Targeted public health and policy efforts are needed to address structural inequities contributing to these disparities.
A new study found that premature birth increases the risk of mortality in adulthood by up to 40% compared to full-term births. Chronic diseases such as heart disease and lung disease also pose a higher risk, with individuals born before 37 weeks having twice the risk of dying from these conditions.
Women with gestational diabetes who prefer evening activity are more likely to experience preeclampsia and have newborns requiring neonatal intensive care. The study suggests that circadian rhythm disturbances may add an additional risk of poor pregnancy outcomes.
A study published in The Endocrine Society's annual meeting found that genetic risk factors for PCOS are associated with obesity, diabetes, cardiovascular disease, and male-pattern baldness in men. This suggests that at least some cases of PCOS may be caused by biological mechanisms common to both men and women.
A study found that women with diabetes are less likely to use effective contraception after their diagnosis, contradicting the American Diabetes Association's recommendation. The researchers hope to improve comprehensive care for pregnant women with diabetes by providing full range of safe and effective contraceptive options.
Despite minimal improvement, racial disparities persist in rural areas for diabetes and high blood pressure-related mortality. However, modest gains were observed for heart disease and stroke mortality in both rural and urban areas.
A large-scale randomized trial involving nearly 24,000 women found no significant differences in health outcomes between two gestational diabetes screening methods. The study evaluated rates of gestational diabetes diagnosis, large-for-gestational-age infants, and adverse perinatal outcomes.
A recent study analyzed US hospital data to describe the characteristics and mortality associated with diabetic ketoacidosis (DKA) among patients with and without COVID-19. The findings indicate a higher mortality rate for DKA patients hospitalized with COVID-19, emphasizing the need for careful management of these cases.
The study found that top-performing primary care clinics in Minnesota used patient data to intensify treatment and monitor outcomes, leading to a significant increase in optimal diabetes care measures. The analysis suggests that this approach may be essential for improving diabetes care outcomes.
Researchers found that genes affecting cilia function are linked to diabetes, kidney failure, and liver fibrosis in both rare genetic disorders and the general public. The discovery opens up new possibilities for targeted treatments and gene therapies.
A modeling study suggests that pre-existing conditions like obesity, hypertension, diabetes, and heart failure contribute to most COVID-19 hospitalizations. The study found that improving cardiometabolic health through lifestyle changes could reduce hospitalizations and health care strains.
A new study found that diabetes patients who used mobile health apps had better health outcomes, including reduced blood glucose levels and increased exercise. The app also helped regulate health behavior and reduce hospital visits and medical expenses.
A recent study published in Diabetologia found that COVID-19 patients with diabetes have a high risk of death and hospitalization, with 21% mortality rate. Factors such as age, treatment with metformin and insulin, and liver enzyme levels were associated with increased mortality risk.
A NIH study found that face masks increase humidity in inhaled air, which can benefit the immune system and combat respiratory diseases like COVID-19. The humidifying effects of masks vary depending on temperature and mask type, with thick cotton masks leading to the most increased level of humidity.
A recent observational study has found a significant association between prediabetes in older adults (ages 71-90) and the risk of progressing to diabetes. The study suggests that age is a key factor in determining the likelihood of disease progression.
Two studies shed light on the process of adding new fat cells, revealing a balance between existing fat cell expansion and new cell creation. A cancer drug can stimulate healthy fat cell formation, while inhibiting the development of new fat cells in one storage area can prevent diseases like diabetes and cardiovascular disease.
The grant will enable UVA Health to serve more underserved groups and rural communities with acute and chronic illnesses, improving patient outcomes and reducing barriers to care.
A recent study published in the Journal of Clinical Endocrinology & Metabolism highlights the need to address health disparities in diabetes by examining systemic racism and its impact on social conditions. The authors recommend implementing culturally and linguistically appropriate services, unconscious bias training, and value divers...
Researchers at Ohio State University discovered a new compound called BC1618 that blocks Fbxo48 and increases Ampk function, improving insulin responses in obese mice. The findings build on previous research to understand protein degradation and may lead to the development of a new class of diabetes drugs.
A CU Anschutz study reveals associations between placental signaling and metabolic disease in children and adults, offering potential early intervention and diagnosis of conditions like diabetes and cardiovascular disease. Placenta function can illuminate future disease in adults and children.
A small, highly controlled study at the National Institutes of Health compared the effects of a low-fat, plant-based diet to a low-carb, animal-based diet on calorie intake, hormone levels, body weight, and more. Participants lost weight on both diets, but only the low-fat diet led to a significant loss of body fat.
A recent study published in Nature Reviews Endocrinology highlights the interconnection between obesity, impaired metabolic health, and COVID-19 severity. The research found that obesity, visceral fatness, and impaired metabolic health are significant risk factors for a more severe course of COVID-19.
A new biomarker of insulin resistance tied to a 600 percent increase in risk of premature coronary heart disease has been discovered. Women under 55 with type-2 diabetes have a tenfold greater risk of having CHD over the next two decades, according to the study published in JAMA Cardiology.
A study analyzing ischemic stroke data from 8,900 patients reveals that female patients have higher crude mortality rates but equal survival rates after controlling for comorbidities. The researchers found no evidence of a sex disparity in stroke recurrence or composite outcomes.
Researchers at Ohio State University Wexner Medical Center and College of Medicine found no link between high doses of saccharin and the development of diabetes in healthy adults. The study isolated saccharin's effects on gut microbiome and metabolic profiles, showing no change in participants.
The Endocrine Society recommends government negotiation, greater transparency, and policy changes to reduce insulin costs. These policies aim to increase access to affordable insulin, particularly for low-income individuals and Medicare beneficiaries.
A recent study from the Buck Institute for Research on Aging reveals that tissue stiffness significantly impacts the innate immune system, contributing to the development of chronic diseases. The research suggests that cellular tension sets off an inflammatory loop, which may be targeted by new force-targeting immunotherapies.
Pregnant women who exercise more during the first trimester of pregnancy may have a lower risk of developing gestational diabetes. The analysis found that exercising at least 38 minutes per day lowers the risk of gestational diabetes by 2.1 cases per 100 women and abnormal blood sugar by 4.8 cases per 100 women.
Researchers improved understanding of intestinal stem cells' renewal and differentiation into specialized cell types. They identified a specific Wnt/planar cell polarity pathway regulating intestinal stem cell self-renewal and lineage decisions, crucial for treating diseases like diabetes and colorectal cancer.
A study published in Nature reveals that the thymus gland plays a crucial role in regulating the immune system and metabolic control during pregnancy. The researchers found that female sex hormones instruct changes in the thymus to produce specialized cells called Tregs, which help prevent miscarriage and gestational diabetes.
A research group at Graz University of Technology is developing an interactive and adaptive health information system that uses machine learning and cognitive psychology to provide personalized content. The system aims to improve doctor-patient communication, enhance health literacy, and make decisions beneficial to users' health.