Articles tagged with Diabetes
A high-protein diet may boost chronic kidney disease and increase the risk of de novo kidney diseases, says a new study. Experts warn that patients with diabetes or obesity who follow a high-protein diet may be at risk of severe kidney damage.
A study by Yale researchers has found that adipose B cells in belly fat unexpectedly proliferate with aging, contributing to increased inflammation and metabolic decline. The expansion can be reversed by reducing macrophage signals and removing adipose B cells.
The Singapore Diabetes Study in Nephropathy and other Microvascular Complications (DYNAMO) aims to reduce DKD prevalence in Singapore by 30% over five years. The study, led by Professor Thomas Coffman, uses a multi-pronged approach to better understand the disease biology and risk factors behind DKD.
Researchers found that healthy men taking commonly prescribed doses of glucocorticoids for a short period experienced changes in blood sugar metabolism, associated with an increased risk of developing diabetes. The study highlights the need for medical professionals to consider and monitor potential side effects.
Research found that SLE Medicaid patients have a double 30-day death rate after coronary revascularization compared to diabetes patients, highlighting the need for further investigation into cardiovascular disease and overall health status in SLE patients.
A new risk calculator tool predicts accurate five-year risk of chronic kidney disease based on variables like age, hypertension, and diabetes status. The tool enables healthcare providers to identify patients at high risk and benefit from preventive interventions.
A new study used data from over 5 million people to develop equations predicting the five-year risk of reduced estimated glomerular filtration rate (eGFR), a key indicator of chronic kidney disease. The findings can help identify individuals at increased risk and potentially prevent or manage the condition.
A new study from Cincinnati Children's Hospital Medical Center reveals that many teenagers who undergo bariatric surgery experience low iron and B12 levels years later. Regular nutrition check-ups and supplementation can minimize these risks, emphasizing the importance of annual assessments.
Researchers found that pioglitazone reduces physical and emotional nicotine withdrawal symptoms in rats and mice. The study suggests that the diabetes drug may help diabetic smokers quit by reducing insulin resistance and alleviating anxiety associated with nicotine withdrawal.
A study led by Duke University Medical Center found that adding weight management counseling to group visits improved diabetes outcomes for patients with uncontrolled diabetes. Participants who received the counseling showed significant weight loss, reduced blood sugar levels, and fewer episodes of hypoglycemia compared to those who on...
Researchers developed a combination gene therapy treating four age-related diseases in mice, including heart failure, kidney failure, diabetes, and obesity. The treatment showed significant improvements, reversing or completely eliminating disease symptoms in obese and diabetic mice.
Researchers found that lower environmental quality in rural counties was associated with a higher prevalence of diabetes. In contrast, urban areas showed a stronger link between air and sociodemographic domains. The study's findings suggest a significant impact of cumulative environmental exposures on diabetes risk in rural populations.
A federally funded study by Johns Hopkins Medicine researchers shows that wearable accelerometers are a reliable tool for predicting death risk in older adults. The research found that an accurate and objective accounting of physical activity outperforms traditional predictors of mortality, such as age, smoking, diabetes, alcohol use, ...
New research found that women with diabetes are up to a quarter less likely to undergo recommended cancer screenings, including cervical, breast, and colorectal cancer tests. The study suggests that the burden of diabetes care management in primary care may contribute to lower uptake of cancer screening.
Researchers identified a single glucose-sensing neuron that controls insulin and glucagon hormone balance in flies, maintaining ideal glucose homeostasis. Silencing this neuron led to hyperglycemia, similar to diabetes in humans, supporting its critical role in regulating sugar levels.
A Swedish study analyzed over 2.5 million births between 1973 and 1997 to examine the health outcomes of people born prematurely. The results show that 54.6% of those born preterm remained healthy without major conditions such as asthma, hypertension, or epilepsy by age 43, compared to 63% of full-term births.
Researchers discovered a delayed and prolonged inflammatory response in diabetic mice infected with MERS-CoV, indicating a malfunction in the body's response to infection. This finding highlights the importance of managing glucose levels in patients with diabetes experiencing respiratory infections.
Kent State University's Gemma Casadesus Smith receives a new two-year NIH grant to investigate the relationship between diabetes, obesity, and Alzheimer's disease. Her research aims to identify early genetic changes and brain transcriptome shifts that contribute to Alzheimer's development.
A systematic review and meta-analysis of six studies with over 200,000 participants found that breastfeeding is associated with a lower risk of developing maternal diabetes and hypertension. The study suggests that breastfeeding may have a protective effect against these conditions.
A new AI screening system has been shown to accurately detect diabetic retinopathy in 95.5% of cases, making real-time screening possible for primary care practices and diabetes centers. The EyeArt system can provide a reading in 60 seconds and does not require the input of an expert ophthalmologist.
A study published in British Journal of Clinical Pharmacology found that statin use for as little as 91 days increased the risk of skin and soft tissue infections. Statin use was also associated with a higher risk of developing diabetes, which is a significant risk factor for these infections.
A study in male rat offspring found that small amounts of alcohol consumed by pregnant mothers can lead to insulin-resistance and an increased likelihood of developing diabetes. The researchers suggest that the lack of oestrogen protection in males may contribute to this sex-specific effect.
New research reveals that maternal obesity accelerates the aging process in offspring, leading to increased susceptibility to diabetes and heart disease. Exercise by the offspring can help mitigate these risks, highlighting the importance of early life conditions on future health outcomes.
The Pharmacist-Led Chronic Care Management Services model has been shown to improve patient outcomes and streamline medication regimens. By integrating pharmacists into the healthcare team, patients receive comprehensive medication management and lifestyle education.
Research investigates how diet and excess blood glucose influence Alzheimer's pathology, providing new insights into the link between diabetes and Alzheimer's disease. The study aims to develop therapies targeting glucose pathways, offering potential treatments for this debilitating condition.
Advances in medications, lifestyle changes, and technologies can help manage post-meal blood sugar levels, but more research is needed to pinpoint a target range and improve clinical outcomes. Small lifestyle changes, such as eating protein and vegetables before carbohydrates, can also lower blood glucose levels.
A comprehensive review of connected diabetes care products found the potential for improved outcomes and reduced healthcare burdens. However, awareness and use of these programs remain low among healthcare professionals and patients.
A systematic review and meta-analysis found that people with diabetes exposed to hypoglycaemia during their admission had an increased average length of stay. The risk of inpatient mortality almost doubled in this group, highlighting the importance of preventing hypoglycaemia to improve patient outcomes.
A recent study by UCSF researchers found that young adults with food insecurity are more likely to develop disorders associated with obesity and obstructive airway diseases like asthma. Chronic stress from food insecurity can lead to inflammation, insulin resistance and increased risk of mental health issues.
A new study finds that increasing levels of 'good' cholesterol reversed disease in the blood vessels of mice with diabetes, reversing atherosclerosis. The study also shows that raising functional HDL levels stopped inflammation and improved cardiovascular disease processes.
A new study by Michigan Medicine and University of Michigan found that nearly one in three low-income people with chronic illnesses discovered a new condition after enrolling in expanded Medicaid. Half of those with chronic conditions reported improved overall health within a year of coverage, with similar improvements in mental health.
An observational study of nearly 230,000 participants found that optimism was associated with a lower risk of cardiovascular events and overall death. The review's findings suggest that interventions promoting optimism may have potential health benefits.
A study of 123,000 patients found that those with mental health disorders had primary care visits before diagnosis and lower overall complication severity scores. Patients with existing mental health disorders also experienced more quickly progressing complications over seven years after diabetes diagnosis.
Researchers found that dual PPARα/γ agonists cause heart dysfunction in diabetes patients due to mitochondrial biogenesis and energy production issues. Activating SIRT1 with resveratrol reduced heart toxicity in mice treated with tesaglitazar, maintaining its therapeutic benefits.
The Affordable Care Act significantly reduced the number of people with diabetes without health insurance. Among those with undiagnosed diabetes, coverage increased from approximately one in four to just eight percent. This shift has substantial implications for the health and economic outcomes of these individuals.
A new study published in Diabetes Care found that racial and ethnic minority groups were more likely to have diabetes or prediabetes at normal or below-normal body mass index (BMI), even among those of normal weight. The research highlights the importance of screening minority patients for diabetes, regardless of their BMI.
A new study reveals a strong association between vitamin D deficiency and increased mortality, particularly in younger and middle-aged individuals. Vitamin D levels of 10 nmol/L or less were associated with a 2-3 fold increase in risk of death, while levels above 90 nmol/L showed a 30-40% reduction in all-cause mortality.
This observational study compared major cardiovascular events among patients with diabetes and reduced kidney function treated with metformin or a sulfonylurea. The study found that metformin was associated with lower rates of cardiovascular events compared to sulfonylureas.
A large meta-analysis of over 2 million pregnancies has found a 53% increased risk of gestational diabetes in women who conceived through IVF compared to natural conception. The study also suggests that pregnancies achieved by assisted reproduction technologies are associated with more obstetric and perinatal complications.
A new study reveals that a protein called caveolin-1 (Cav-1) is depleted in the temporal lobe of humans with type-2 diabetes and in a diabetic mouse model, leading to increased Alzheimer's disease pathology. Restoring Cav-1 levels in mice reduced Alzheimer's pathology and improved learning and memory deficits.
The study found that men and women experience different comorbidities as having diabetes or prediabetes, including a higher rate of prediabetes among children. Prediabetic women showed a higher prevalence of osteoporosis and depression compared to men.
A new study found that Japanese-American adults with a normal body mass index have a significantly higher risk of developing diabetes compared to their non-Hispanic white counterparts. The study revealed that younger respondents, never smokers, and those with higher education levels were less likely to have diabetes.
Researchers have discovered new members of a protein complex that maintains functional beta cells in the pancreas, crucial for regulating blood glucose levels. The study reveals the complex's association with enzymes RNF20 and RNF40, which play a key role in gene expression and insulin release.
Patients with diabetes are at greater risk of developing heart failure after a heart attack, with a 56% higher risk compared to those without diabetes. The study also found that diabetic patients who develop heart failure have a much higher risk of dying in the following years.
The THEMIS trial found that ticagrelor, when added to aspirin, reduced the risk of cardiovascular death, heart attack, or stroke by 10% in patients with stable coronary artery disease and diabetes. However, patients taking dual antiplatelet therapy also experienced a greater risk of major bleeding.
A low-cost text-messaging programme improves blood sugar control in patients with diabetes and coronary heart disease. The programme, which consisted of six messages per week, resulted in a significant reduction in HbA1c levels and an increase in participants achieving the target level of less than 7%.
A new Northwestern Medicine study finds total heart disease deaths increasing since 2011, with a significant portion of deaths preventable. The study's authors call for a shift in focus towards prevention to combat cardiovascular disease.
Researchers found that postnatal overnutrition in mice leads to premature epigenetic aging in pancreatic islets, increasing the risk of diabetes. Early life overnutrition accelerates DNA methylation changes, resembling those of middle-aged mice, and contributes to impaired glucose regulation.
Researchers identified patterns in cellular behavior that could lead to diagnosis and treatment of chronic diseases. The team developed a biophysical model of energy-driven cellular machinery for understanding allostasis in cells.
Research published in Annals of Internal Medicine found that both general and abdominal obesity were strongly associated with mortality among Mexican adults. The study, which followed over 115,000 adults for up to 14 years, also found that waist-to-hip ratio was a major risk factor for premature death.
A new study by Massachusetts General Hospital finds that more than one in four US adults with diabetes were not diagnosed, while nearly one in three received inadequate care. Younger, female, and non-white adults were particularly affected by disparities in meeting treatment targets.
The Endocrine Society recommends regularly screening older adults for heart disease and diabetes risk, prioritizing lifestyle modification as the first-line therapy. Patients with at least three metabolic risk factors should be screened annually, while those with one or two risk factors should be screened every three years.
The University of Bern and Diabetes Center Berne create four tenure-track assistant professorships in diabetes technology and clinical research. The positions will focus on translating research into clinical use and improving patient outcomes.
A single viral factor released from HIV-infected cells impairs cholesterol metabolism in uninfected cells, triggering inflammation and contributing to the development of diseases such as dementia, heart disease, and diabetes. Targeted treatment may provide a longer and healthier life for people living with HIV/AIDS.
Researchers developed a predictive risk model to identify patients with diabetes at high risk of low blood sugar. The model combines known risk factors, including recent infections, insulin use, and dementia, to help healthcare providers intervene and prevent serious adverse events.
A Mediterranean-style diet rich in tree nuts like walnuts and extra virgin olive oil was found to improve maternal health outcomes during pregnancy, including a reduced risk of gestational diabetes. Women who followed the diet gained an average of 2.75 pounds less than those receiving standard prenatal care.
A team of scientists has identified a key molecular connection between diabetes and vascular disease, finding that high blood glucose activates an enzyme that constricts blood vessels. The study aims to develop new treatments targeting this pathway for reducing vascular complications of diabetes.
A study of over 900,000 VA patients found that routine blood tests with random plasma glucose levels below 200 mg/dL can accurately predict the development of diabetes. Patients with high glucose levels are more likely to be diagnosed with diabetes in the future, making this test a valuable tool for early intervention and prevention.
Research by UMass Amherst epidemiologist Youssef Oulhote found that women with gestational diabetes have a significantly higher rate of transferring synthetic chemicals to their fetus. The study examined blood and umbilical cord samples from 151 mother-newborn pairs in the Faroe Islands.
Researchers identified a molecular mechanism that may be contributing to the global obesity epidemic. The study found that a protein called RAGE on the surface of fat cells can block fat burning when stressed, leading to weight gain. Removing RAGE from fat cells reduced weight gain in mice fed a high-fat diet.