Articles tagged with Diabetes
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A new longitudinal study shows a link between multiple metabolic disorders in mothers during pregnancy and children's body mass indexes later in life. The study found that when a mother experiences both gestational diabetes and preeclampsia, the child has an increased risk of high childhood BMI over time.
A 16-year study of Hong Kong's population found that death rates from all-cause mortality, cardiovascular disease, and cancer decreased significantly in older adults with diabetes. In contrast, younger adults with diabetes experienced little to no change in their death rates over the same period. The researchers suggest that targeted p...
A new computer algorithm can predict in early pregnancy or before pregnancy which women are at high risk of gestational diabetes. The study analyzed data on nearly 600,000 pregnancies and identified nine parameters that accurately predicted the risk of developing gestational diabetes.
A new study by researchers from Boston University School of Public Health and Chulalongkorn Universities identified strengths and weaknesses in Thailand's diabetes care. The majority of Thai adults with diabetes were never diagnosed, but most who were diagnosed received treatment and controlled their condition.
Researchers at Stockholm University discovered engineered silica particles can reduce food efficiency, leading to lower weight gain and improved metabolic profiles in mice. The study suggests these particles could be used to treat obesity and diabetes in humans.
Researchers developed a smart photonic contact lens that measures glucose concentration in conjunctival blood vessels, enabling diabetic diagnosis. The device also shows promise for treating diabetic retinopathy by reducing angiogenesis and verifying clinical feasibility.
Scientists have developed a non-fibrillating form of human insulin called glycoinsulin, which demonstrates the same glucose-lowering effects as native insulin without fibril formation. This discovery presents a promising solution for patients relying on insulin pumps and could improve the shelf life of insulin products.
A population study found that diabetes is an independent risk factor for heart failure, with 21% of diabetic patients developing heart failure over a 10-year period. This study supports the concept of diabetic cardiomyopathy and highlights the need for further research into this association.
Researchers at Helmholtz Munich have created a technique called Mid-infraRed Optoacoustic Microscopy (MiROM) that provides real-time images of biomolecules in living cells without the need for labels or contrast agents. This method offers novel insights into metabolic processes and can be used to study the effects of different diets on...
A genetic risk score can identify individuals at a 3-fold increased risk of developing ischaemic stroke, a devastating condition. This scoring system may require more intensive preventive measures than current guidelines recommend.
This observational study found that the age-sex-adjusted proportion of US adults with diabetes was 12.1% for non-Hispanic whites, 20.4% for non-Hispanic blacks, 22.1% for Hispanics, and 19.1% for non-Hispanic Asians. Notably, Hispanic and non-Hispanic Asian subpopulations showed significant differences in undiagnosed diabetes rates.
A new national study found that walking and cycling to work were associated with a significant reduction in heart attacks. For women who walked to work, there was an associated 1.7% reduction in heart attacks the following year, while men who cycled to work experienced the same decrease.
The global diabetes epidemic is reaching epidemic levels, with 425 million people affected and projected to increase to over 600 million. The book 'Traveling with Sugar' examines the havoc diabetes has caused in Belize, highlighting the need for improved infrastructure for treating the condition.
A team of researchers at Wayne State University is developing a novel oral insulin delivery system to address the issues of low absorption and bioavailability. The goal is to create a safe and efficient treatment that can enhance the quality of life for diabetes patients.
Researchers discovered a connection between gastric bypass surgery and the release of glucagon-like peptide-1 (GLP-1), a hormone regulating appetite. The study found that mHMGCS, an enzyme triggering ketone body formation in the small intestine, inhibits GLP-1 release.
A new UBC study finds that many Canadians live with multiple chronic health conditions, including cardiometabolic diseases like stroke, heart disease, and diabetes. Lifestyle behaviors such as physical inactivity, poor diet, and high stress levels are associated with a higher risk of developing these conditions.
A Hebrew University study found pregnant women who smoke are nearly 50% more likely to develop gestational diabetes. Women who cut down on their cigarette intake still face a 22% higher risk compared to non-smokers or those who quit before pregnancy.
A study by University of Utah Health found that people with chronic illnesses turn to underground exchanges for medicines and supplies due to affordability and accessibility issues. Many participants donated or traded goods with family, friends, or strangers who couldn't get them through traditional channels.
Rates of cardiac events such as heart failure and myocardial infarction decreased up to 60% among First Nations people with diabetes in Ontario. However, hospitalizations and deaths remained more frequent compared to non-First Nations individuals.
University of Delaware researchers identify gene expression irregularities and lipoprotein lipase enzyme as causes of wooden breast syndrome in broiler chickens. This metabolic disorder can make the meat hard and chewy, causing significant economic losses for growers.
Researchers found that high levels of DDT in Indian immigrants' blood correlated with obesity, liver fat accumulation, and insulin resistance. The study suggests that prior exposure to persistent organic pollutants may contribute to the higher diabetes risk among Asian Indians.
A study from the University of California, Davis found a link between high levels of DDT and increased risk of obesity, insulin resistance, and metabolic disease in Asian Indian immigrants. Prior exposure to the pollutant may contribute to their higher rate of diabetes, even after migration to the US.
A high-protein diet may boost chronic kidney disease and increase the risk of de novo kidney diseases, says a new study. Experts warn that patients with diabetes or obesity who follow a high-protein diet may be at risk of severe kidney damage.
A study by Yale researchers has found that adipose B cells in belly fat unexpectedly proliferate with aging, contributing to increased inflammation and metabolic decline. The expansion can be reversed by reducing macrophage signals and removing adipose B cells.
The Singapore Diabetes Study in Nephropathy and other Microvascular Complications (DYNAMO) aims to reduce DKD prevalence in Singapore by 30% over five years. The study, led by Professor Thomas Coffman, uses a multi-pronged approach to better understand the disease biology and risk factors behind DKD.
Researchers found that healthy men taking commonly prescribed doses of glucocorticoids for a short period experienced changes in blood sugar metabolism, associated with an increased risk of developing diabetes. The study highlights the need for medical professionals to consider and monitor potential side effects.
Research found that SLE Medicaid patients have a double 30-day death rate after coronary revascularization compared to diabetes patients, highlighting the need for further investigation into cardiovascular disease and overall health status in SLE patients.
A new study from Cincinnati Children's Hospital Medical Center reveals that many teenagers who undergo bariatric surgery experience low iron and B12 levels years later. Regular nutrition check-ups and supplementation can minimize these risks, emphasizing the importance of annual assessments.
A new risk calculator tool predicts accurate five-year risk of chronic kidney disease based on variables like age, hypertension, and diabetes status. The tool enables healthcare providers to identify patients at high risk and benefit from preventive interventions.
A new study used data from over 5 million people to develop equations predicting the five-year risk of reduced estimated glomerular filtration rate (eGFR), a key indicator of chronic kidney disease. The findings can help identify individuals at increased risk and potentially prevent or manage the condition.
A study led by Duke University Medical Center found that adding weight management counseling to group visits improved diabetes outcomes for patients with uncontrolled diabetes. Participants who received the counseling showed significant weight loss, reduced blood sugar levels, and fewer episodes of hypoglycemia compared to those who on...
Researchers developed a combination gene therapy treating four age-related diseases in mice, including heart failure, kidney failure, diabetes, and obesity. The treatment showed significant improvements, reversing or completely eliminating disease symptoms in obese and diabetic mice.
Researchers found that pioglitazone reduces physical and emotional nicotine withdrawal symptoms in rats and mice. The study suggests that the diabetes drug may help diabetic smokers quit by reducing insulin resistance and alleviating anxiety associated with nicotine withdrawal.
Researchers found that lower environmental quality in rural counties was associated with a higher prevalence of diabetes. In contrast, urban areas showed a stronger link between air and sociodemographic domains. The study's findings suggest a significant impact of cumulative environmental exposures on diabetes risk in rural populations.
A federally funded study by Johns Hopkins Medicine researchers shows that wearable accelerometers are a reliable tool for predicting death risk in older adults. The research found that an accurate and objective accounting of physical activity outperforms traditional predictors of mortality, such as age, smoking, diabetes, alcohol use, ...
New research found that women with diabetes are up to a quarter less likely to undergo recommended cancer screenings, including cervical, breast, and colorectal cancer tests. The study suggests that the burden of diabetes care management in primary care may contribute to lower uptake of cancer screening.
Researchers identified a single glucose-sensing neuron that controls insulin and glucagon hormone balance in flies, maintaining ideal glucose homeostasis. Silencing this neuron led to hyperglycemia, similar to diabetes in humans, supporting its critical role in regulating sugar levels.
A Swedish study analyzed over 2.5 million births between 1973 and 1997 to examine the health outcomes of people born prematurely. The results show that 54.6% of those born preterm remained healthy without major conditions such as asthma, hypertension, or epilepsy by age 43, compared to 63% of full-term births.
Researchers discovered a delayed and prolonged inflammatory response in diabetic mice infected with MERS-CoV, indicating a malfunction in the body's response to infection. This finding highlights the importance of managing glucose levels in patients with diabetes experiencing respiratory infections.
Kent State University's Gemma Casadesus Smith receives a new two-year NIH grant to investigate the relationship between diabetes, obesity, and Alzheimer's disease. Her research aims to identify early genetic changes and brain transcriptome shifts that contribute to Alzheimer's development.
A systematic review and meta-analysis of six studies with over 200,000 participants found that breastfeeding is associated with a lower risk of developing maternal diabetes and hypertension. The study suggests that breastfeeding may have a protective effect against these conditions.
A new AI screening system has been shown to accurately detect diabetic retinopathy in 95.5% of cases, making real-time screening possible for primary care practices and diabetes centers. The EyeArt system can provide a reading in 60 seconds and does not require the input of an expert ophthalmologist.
A study published in British Journal of Clinical Pharmacology found that statin use for as little as 91 days increased the risk of skin and soft tissue infections. Statin use was also associated with a higher risk of developing diabetes, which is a significant risk factor for these infections.
A study in male rat offspring found that small amounts of alcohol consumed by pregnant mothers can lead to insulin-resistance and an increased likelihood of developing diabetes. The researchers suggest that the lack of oestrogen protection in males may contribute to this sex-specific effect.
The Pharmacist-Led Chronic Care Management Services model has been shown to improve patient outcomes and streamline medication regimens. By integrating pharmacists into the healthcare team, patients receive comprehensive medication management and lifestyle education.
New research reveals that maternal obesity accelerates the aging process in offspring, leading to increased susceptibility to diabetes and heart disease. Exercise by the offspring can help mitigate these risks, highlighting the importance of early life conditions on future health outcomes.
Advances in medications, lifestyle changes, and technologies can help manage post-meal blood sugar levels, but more research is needed to pinpoint a target range and improve clinical outcomes. Small lifestyle changes, such as eating protein and vegetables before carbohydrates, can also lower blood glucose levels.
Research investigates how diet and excess blood glucose influence Alzheimer's pathology, providing new insights into the link between diabetes and Alzheimer's disease. The study aims to develop therapies targeting glucose pathways, offering potential treatments for this debilitating condition.
A comprehensive review of connected diabetes care products found the potential for improved outcomes and reduced healthcare burdens. However, awareness and use of these programs remain low among healthcare professionals and patients.
A systematic review and meta-analysis found that people with diabetes exposed to hypoglycaemia during their admission had an increased average length of stay. The risk of inpatient mortality almost doubled in this group, highlighting the importance of preventing hypoglycaemia to improve patient outcomes.
A recent study by UCSF researchers found that young adults with food insecurity are more likely to develop disorders associated with obesity and obstructive airway diseases like asthma. Chronic stress from food insecurity can lead to inflammation, insulin resistance and increased risk of mental health issues.
A new study finds that increasing levels of 'good' cholesterol reversed disease in the blood vessels of mice with diabetes, reversing atherosclerosis. The study also shows that raising functional HDL levels stopped inflammation and improved cardiovascular disease processes.
A new study by Michigan Medicine and University of Michigan found that nearly one in three low-income people with chronic illnesses discovered a new condition after enrolling in expanded Medicaid. Half of those with chronic conditions reported improved overall health within a year of coverage, with similar improvements in mental health.
An observational study of nearly 230,000 participants found that optimism was associated with a lower risk of cardiovascular events and overall death. The review's findings suggest that interventions promoting optimism may have potential health benefits.
A study of 123,000 patients found that those with mental health disorders had primary care visits before diagnosis and lower overall complication severity scores. Patients with existing mental health disorders also experienced more quickly progressing complications over seven years after diabetes diagnosis.
Researchers found that dual PPARα/γ agonists cause heart dysfunction in diabetes patients due to mitochondrial biogenesis and energy production issues. Activating SIRT1 with resveratrol reduced heart toxicity in mice treated with tesaglitazar, maintaining its therapeutic benefits.
The Affordable Care Act significantly reduced the number of people with diabetes without health insurance. Among those with undiagnosed diabetes, coverage increased from approximately one in four to just eight percent. This shift has substantial implications for the health and economic outcomes of these individuals.
This observational study compared major cardiovascular events among patients with diabetes and reduced kidney function treated with metformin or a sulfonylurea. The study found that metformin was associated with lower rates of cardiovascular events compared to sulfonylureas.
A new study published in Diabetes Care found that racial and ethnic minority groups were more likely to have diabetes or prediabetes at normal or below-normal body mass index (BMI), even among those of normal weight. The research highlights the importance of screening minority patients for diabetes, regardless of their BMI.
A new study reveals a strong association between vitamin D deficiency and increased mortality, particularly in younger and middle-aged individuals. Vitamin D levels of 10 nmol/L or less were associated with a 2-3 fold increase in risk of death, while levels above 90 nmol/L showed a 30-40% reduction in all-cause mortality.