Research on diabetes and its complications. Covers glucose prediction, nerve pain, weight-loss drugs, insulin access, and diabetes management.
Researchers found that heritage-specific diets varied across Latinx groups, with Mexican and Puerto Rican diets being healthier. The study suggests that longer years living in the US may lead to less healthy dietary patterns among Cuban, Mexican, and Puerto Rican groups.
Research highlights the importance of normal insulin cycles for metabolic health, including better response to fed and fasted insulin inputs. It also uncovers mechanisms regulating robustness of insulin signaling, identifying potential novel regulatory components for therapeutic interventions.
A new study suggests that a plant-based diet can improve vaccine efficacy and reduce COVID-related health issues. Studies have shown that healthcare workers with lower waist circumferences had better immune responses to the Pfizer vaccine.
A new patient decision aid developed by Duke-NUS Medical School's experts empowers patients with ESKD to choose care strategies consistent with their values and goals. The tool provides a balanced overview of dialysis, kidney supportive care, and other treatment options.
The Rutgers-NYU Center for Asian Health Promotion and Equity aims to address significant disparities in the Asian community's relationship with heart health and mental health. The center will focus on cardiometabolic disease and mental health research to inform practice and policy at local, regional, and national levels.
A large observational study found statin use associated with faster diabetes progression in patients with diabetes. The study included 83,000 matched pairs and followed them for an average of 2 years.
Researchers found that COVID-19 patients with high blood sugar levels were more likely to develop severe lung dysfunction, require mechanical ventilation, and die. The study also suggests that SARS-CoV-2 may disrupt fat cells' production of adiponectin, a hormone regulating blood sugar levels.
Experts recommend prioritizing obesity treatment over glucose control in Type 2 diabetes. Dropping 15% of body weight can have a disease-modifying effect, according to UT Southwestern's Ildiko Lingvay.
A new study published in Neurology suggests that people with diabetes who have had a stroke may benefit from maintaining blood sugar levels between 6.8% and 7.0% to lower the risk of future vascular events. The study found that those admitted to the hospital with A1C levels above 7.0% were at increased risk for heart attacks and strokes.
A study published in Communications Biology reveals that chronic hyperglycemia in diabetes impairs working memory performance by altering the connection between key brain regions. Researchers found that areas critical for forming and retrieving memories were over-connected, leading to errors in remembering correct information.
Researchers used human pluripotent stem cells and organoids to study SARS-CoV-2 infection, finding that it can infect multiple cell types, including lung, colon, heart, liver, and pancreatic cells. The virus alters cellular function, including reducing insulin production in pancreatic beta cells.
The ACE2 protein plays a key role in the damage done to insulin-producing cells of the pancreas, increasing the risk of complications from SARS-CoV-2 infections. Inflammation can lead to increased expression of ACE2, making these cells more susceptible to viral infection.
A University of Illinois study found that parental income has a lasting impact on children's health, with lower socioeconomic status linked to increased risk of obesity and related conditions. Permanent income is associated with parents' general socioeconomic conditions, while transitory peaks during adolescence can promote better health.
Researchers analyzed data from nearly 3 million adults and found that those with 'metabolically healthy obesity' had a higher risk of developing heart failure and atrial fibrillation. However, they were not at increased risk for heart attacks, strokes, or cardiovascular deaths.
A UK study analyzing laboratory testing data reveals widespread impact of the COVID-19 pandemic on people with and being investigated for diabetes. The study estimates that 2.5 million diagnostic tests were missed or delayed during the 6-month lockdown, including 1.4 million monitoring tests in people with diabetes.
A study by Belgian researchers found that maintaining a diabetic foot care program during the COVID-19 pandemic resulted in fewer late presentations and less severe ulcers. Despite lockdown restrictions, 23 of 24 clinics remained open for urgent care, applying measures such as remote consultations and physical distancing.
A serum biomarker, polyubiquitinated phosphatase and tensin homolog (PTEN), was associated with a four-fold higher risk of kidney function decline. This modified form of PTEN was linked to severity of lesions in kidney structure, indicating early manifestations of diabetic kidney disease.
A study published by The BMJ found that giving metformin to women with preterm pre-eclampsia may prolong pregnancy by a week, but the result was not statistically significant. If confirmed by future research, this could have important benefits for both mother and baby.
A new global study found that setting targets for treating diabetes patients with cholesterol or blood pressure medication can significantly improve cardiovascular outcomes. Achieving these targets could save up to 6% of healthy lifetime lost to diabetes over 10 years, mainly due to reduced cardiovascular conditions.
A study found that 73% of hospitalized COVID-19 patients developed delirium, leading to lasting cognitive impairment and increased need for skilled nursing care. The disease itself, sedatives, and inflammation can contribute to this outcome.
Increasing physical activity and improving fitness are superior to weight loss in reducing mortality risk and treating obesity-related health conditions. Employing a weight-neutral approach also reduces the risks associated with yo-yo dieting.
A new study suggests that failing to meet sleep recommendations can lead to higher intake of non-meal calories, including carbohydrates, added sugar, fats, and caffeine. Adults who don't get enough sleep tend to make poorer snacking choices, such as reaching for salty snacks and sweets.
A two-hour glucose tolerance test is linked to cognitive decline in a 10-year follow-up study. Higher blood glucose levels measured in the test were associated with weaker performance in a memory test and a greater decline in results.
Researchers at Penn State have imaged a protein facilitating RNA modification, allowing them to reconstruct the process. The study reveals how a chemical tag is added to tRNA, improving its ability to translate messenger RNA into proteins.
Researchers from Pusan National University have compiled a comprehensive review of ginsenosides, the main component of ginseng, which can prevent inflammation, diabetes, and cancer. The study provides insights into how to improve ginsenoside production through chemical and enzymatic treatments, as well as microbial action.
Researchers at Umeå University developed a method to study specific cell types in human organs with high-resolution 3D imaging. This allows for the visualization of previously unrecognized alterations in organs like the pancreas, which can lead to improved understanding of disease conditions and treatment options.
Researchers developed an experimental device to improve blood sugar control in HI patients. The bihormonal bionic pancreas (BHBP) helps maintain stable glucose levels without human error in calculating doses.
The study found large reductions in uninsurance and improvements in blood pressure and blood sugar control among Hispanic and Black patients after Medicaid expansion. The first five years of expansion were associated with significant benefits for these populations.
A new study found that Medicaid expansion is associated with reductions in uninsurance and improvements in blood pressure and glucose control measurements. The benefits were highest among Black and Hispanic patients. Longer-term investments into quality care and care management are necessary to realize these health outcomes.
Researchers have found that maternal diabetes can cause premature aging of neural tissue, leading to birth defects such as neural tube defects. A study published in Science Advances suggests that treatments could be developed to prevent miscarriages and certain birth defects in babies born from mothers with diabetes.
Researchers found that certain species of gut bacteria accumulate human drugs, altering their types, activity, and metabolism. This can change the effectiveness of the drug both directly and indirectly, affecting side effects.
A recent study published in Scientific Reports found that individuals with inflexible metabolisms exhibit higher carbohydrate oxidation rates at night, indicating a reduced ability to burn fat during sleep. This discovery has the potential for practical use in disease prevention and early intervention.
Researchers have found that blocking DHPS, an enzyme necessary for activating elF5A, can reduce inflammation and improve glucose control in mice. The study suggests macrophages play a key role in inflammation in obesity, and targeting this pathway may be a promising approach to treating the condition.
A study from Michigan Medicine found that people with type 2 diabetes are more likely to develop a cytokine storm during coronavirus infection due to the enzyme SETDB2. Administering interferon beta increased SETDB2 and decreased inflammatory cytokines in diabetic mice, offering potential therapy for severe COVID-19.
Researchers found significant disparities in diabetes diagnosis ages among US racial and ethnic groups. Younger Hispanic individuals were more likely to be diagnosed at a younger age compared to non-Hispanic whites and other racial groups.
Researchers from the University of Copenhagen have discovered a hormone in fruit flies that regulates human metabolism, potentially leading to new treatments for obesity and diabetes. The CAPA hormone plays a crucial role in maintaining energy balance, raising blood sugar levels, and regulating insulin secretion.
Researchers at Nanyang Technological University have developed a 3D model of the human artery blood vessel wall to study atherosclerosis. The model, called an 'arterial wall-on-a-chip', helps understand how cholesterol and inflammatory cells contribute to the disease.
A controlled trial found that consuming an avocado daily for 12 weeks reduced visceral abdominal fat and the ratio of visceral to subcutaneous fat in female participants. The benefits were primarily seen in females, with no impact on glucose tolerance or male participants.
A nationwide study of transgender individuals in the Netherlands found a significantly increased mortality risk compared to cisgender people. The analysis of national data from 1972 to 2018 revealed that transgender women and men faced higher risks of cardiovascular disease, lung cancer, infection, and non-natural causes of death.
A new study found that women are experiencing a greater increase in non-traditional cardiovascular risk factors, such as work stress and sleep disorders, compared to men. The trend coincides with an increase in women working full-time, highlighting the need for prevention strategies to address these emerging risks.
A comprehensive review reveals how excessive fructose intake can disrupt metabolic pathways, leading to diseases such as diabetes, fatty liver disease, and heart disease. The study highlights the role of protein transporters, gluconeogenesis, and gene-level changes in regulating fructose metabolism.
The European Society of Cardiology's new guidelines emphasize the importance of individualized risk estimation and tailored treatment approaches to prevent cardiovascular disease. The guidelines recommend a healthy diet, regular exercise, and smoking cessation as key measures to reduce CVD risk.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
A large study found that people with hypertension or diabetes often lack a simple urine test for protein in the urine, despite being at high risk of chronic kidney disease. The researchers suggest widening albuminuria testing to detect early chronic kidney diseases and emphasize the importance of treatment.
Gestational diabetes rates in the US have increased among certain racial and ethnic groups between 2011 and 2019, highlighting persistent health inequities. The study found that Hispanic women had significantly higher rates of gestational diabetes compared to non-Hispanic white, black, or Asian women.
A new study examining the association between type 2 diabetes mellitus and skin diseases reveals a strong link between the two conditions. The research, published in Chinese Medical Journal, found that 93.5% of individuals with T2DM had skin problems, including over 47 types of comorbid skin diseases.
A large-scale surveillance study in Madurai, India, found that comorbidities are a significant predictor of positive RT-PCR testing. The study also revealed an equal risk of asymptomatic infection among children, teenagers, and working-age adults, highlighting the importance of non-communicable disease control in COVID-19 containment s...
Researchers at Indiana University School of Optometry have identified new biomarkers that can detect early eye changes associated with diabetes-related blindness. The study's findings may lead to earlier identification of people at risk for diabetes or visual impairment.
The University of Maryland associate professor will use genetics, cell biology, and pharmacology to examine the mechanisms of copper transport and its connection to thermogenesis and fat burning. The research aims to improve human health by understanding how copper relates to hypothermia, obesity, and diabetes.
A recent study found that rates of minor lower extremity amputations increased between 2009 and 2017 in rural and Western American residents, Native Americans, and Asian Americans/Pacific Islanders. Major LEAs rates remained steady during the period with notable increases in White populations and rural areas.
Researchers found that a gene called REST is crucial for boosting insulin-producing cells during early pancreas development. Inactivating this gene increased the number of insulin-producing cells, which were maintained into adulthood in mice.
The US Preventive Services Task Force (USPSTF) has made a recommendation to screen for gestational diabetes in asymptomatic pregnant women at 24 weeks or later. The organization concludes that the current evidence is insufficient to make a recommendation about screening before this time frame.
A new study found that individuals with diabetes are significantly more likely to be hospitalized and have a greater risk of dying from infections. The research showed that the risk was more pronounced in younger adults with diabetes and black people, with an increased likelihood of both common and rare infections. This association bet...
A comprehensive review of keto diets found potential health risks, including increased heart disease risk, cancer risk, and adverse effects on pregnant women and kidney patients. For most people, the possible long-term benefits of a keto diet are outweighed by its potential drawbacks.
A WVU researcher is launching a pilot program to prevent amputations in West Virginia, utilizing an NIH grant. The program aims to reduce mortality rates by educating the population and primary care providers about peripheral artery disease and foot exams.
A recent study published in Frontiers in Nutrition found that consuming millet as part of a daily diet can reduce blood glucose levels by 12-15% and help manage diabetes. The research, which analyzed data from over 1,000 human subjects across 11 countries, also found that millets have a lower glycemic index compared to other grains.
A new study published in Nutrients highlights the importance of adequate protein intake for adults living with diabetes. The research found that nearly half of US adults with diabetes did not meet the daily recommended protein intake, leading to greater physical limitations and potentially increasing the risk of muscle loss.
A Harvard study found that 20% of diabetes patients with high-deductible health plans reported skipping medications due to cost, compared to 16% in traditional plans. Patients with insulin reliance were 31% more likely to miss medication.
Researchers have identified a recurring trend of elevated blood glucose levels among those with severe Covid-19, which impairs lung immune defense and facilitates cytokine storm. Tight control and management of glycemia may be crucial for better outcomes, and metformin shows potential as a treatment option.
The American College of Cardiology has issued clinical guidance on reducing ASCVD risk in patients with persistent hypertriglyceridemia, recommending lifestyle intervention and non-statin therapies. The guidance emphasizes the importance of individualized nutrition guidance for these patients.