Articles tagged with Diabetes
A recent study published in Scientific Reports found that individuals with inflexible metabolisms exhibit higher carbohydrate oxidation rates at night, indicating a reduced ability to burn fat during sleep. This discovery has the potential for practical use in disease prevention and early intervention.
A study from Michigan Medicine found that people with type 2 diabetes are more likely to develop a cytokine storm during coronavirus infection due to the enzyme SETDB2. Administering interferon beta increased SETDB2 and decreased inflammatory cytokines in diabetic mice, offering potential therapy for severe COVID-19.
Researchers found significant disparities in diabetes diagnosis ages among US racial and ethnic groups. Younger Hispanic individuals were more likely to be diagnosed at a younger age compared to non-Hispanic whites and other racial groups.
Researchers have found that blocking DHPS, an enzyme necessary for activating elF5A, can reduce inflammation and improve glucose control in mice. The study suggests macrophages play a key role in inflammation in obesity, and targeting this pathway may be a promising approach to treating the condition.
Researchers from the University of Copenhagen have discovered a hormone in fruit flies that regulates human metabolism, potentially leading to new treatments for obesity and diabetes. The CAPA hormone plays a crucial role in maintaining energy balance, raising blood sugar levels, and regulating insulin secretion.
A controlled trial found that consuming an avocado daily for 12 weeks reduced visceral abdominal fat and the ratio of visceral to subcutaneous fat in female participants. The benefits were primarily seen in females, with no impact on glucose tolerance or male participants.
Researchers at Nanyang Technological University have developed a 3D model of the human artery blood vessel wall to study atherosclerosis. The model, called an 'arterial wall-on-a-chip', helps understand how cholesterol and inflammatory cells contribute to the disease.
A nationwide study of transgender individuals in the Netherlands found a significantly increased mortality risk compared to cisgender people. The analysis of national data from 1972 to 2018 revealed that transgender women and men faced higher risks of cardiovascular disease, lung cancer, infection, and non-natural causes of death.
A new study found that women are experiencing a greater increase in non-traditional cardiovascular risk factors, such as work stress and sleep disorders, compared to men. The trend coincides with an increase in women working full-time, highlighting the need for prevention strategies to address these emerging risks.
A comprehensive review reveals how excessive fructose intake can disrupt metabolic pathways, leading to diseases such as diabetes, fatty liver disease, and heart disease. The study highlights the role of protein transporters, gluconeogenesis, and gene-level changes in regulating fructose metabolism.
The European Society of Cardiology's new guidelines emphasize the importance of individualized risk estimation and tailored treatment approaches to prevent cardiovascular disease. The guidelines recommend a healthy diet, regular exercise, and smoking cessation as key measures to reduce CVD risk.
Researchers from Tokyo University of Science developed a self-powered diaper sensor that monitors urine sugar levels, providing an alternative biomarker for blood sugar monitoring. The sensor uses a biofuel cell powered by glucose in the urine, detecting sugar levels within 1 second and simplifying caretaking tasks.
A large study found that people with hypertension or diabetes often lack a simple urine test for protein in the urine, despite being at high risk of chronic kidney disease. The researchers suggest widening albuminuria testing to detect early chronic kidney diseases and emphasize the importance of treatment.
Gestational diabetes rates in the US have increased among certain racial and ethnic groups between 2011 and 2019, highlighting persistent health inequities. The study found that Hispanic women had significantly higher rates of gestational diabetes compared to non-Hispanic white, black, or Asian women.
A large-scale surveillance study in Madurai, India, found that comorbidities are a significant predictor of positive RT-PCR testing. The study also revealed an equal risk of asymptomatic infection among children, teenagers, and working-age adults, highlighting the importance of non-communicable disease control in COVID-19 containment s...
A new study examining the association between type 2 diabetes mellitus and skin diseases reveals a strong link between the two conditions. The research, published in Chinese Medical Journal, found that 93.5% of individuals with T2DM had skin problems, including over 47 types of comorbid skin diseases.
Researchers at Indiana University School of Optometry have identified new biomarkers that can detect early eye changes associated with diabetes-related blindness. The study's findings may lead to earlier identification of people at risk for diabetes or visual impairment.
The University of Maryland associate professor will use genetics, cell biology, and pharmacology to examine the mechanisms of copper transport and its connection to thermogenesis and fat burning. The research aims to improve human health by understanding how copper relates to hypothermia, obesity, and diabetes.
A recent study found that rates of minor lower extremity amputations increased between 2009 and 2017 in rural and Western American residents, Native Americans, and Asian Americans/Pacific Islanders. Major LEAs rates remained steady during the period with notable increases in White populations and rural areas.
Researchers found that a gene called REST is crucial for boosting insulin-producing cells during early pancreas development. Inactivating this gene increased the number of insulin-producing cells, which were maintained into adulthood in mice.
The US Preventive Services Task Force (USPSTF) has made a recommendation to screen for gestational diabetes in asymptomatic pregnant women at 24 weeks or later. The organization concludes that the current evidence is insufficient to make a recommendation about screening before this time frame.
A new study found that individuals with diabetes are significantly more likely to be hospitalized and have a greater risk of dying from infections. The research showed that the risk was more pronounced in younger adults with diabetes and black people, with an increased likelihood of both common and rare infections. This association bet...
A WVU researcher is launching a pilot program to prevent amputations in West Virginia, utilizing an NIH grant. The program aims to reduce mortality rates by educating the population and primary care providers about peripheral artery disease and foot exams.
A comprehensive review of keto diets found potential health risks, including increased heart disease risk, cancer risk, and adverse effects on pregnant women and kidney patients. For most people, the possible long-term benefits of a keto diet are outweighed by its potential drawbacks.
A recent study published in Frontiers in Nutrition found that consuming millet as part of a daily diet can reduce blood glucose levels by 12-15% and help manage diabetes. The research, which analyzed data from over 1,000 human subjects across 11 countries, also found that millets have a lower glycemic index compared to other grains.
A new study published in Nutrients highlights the importance of adequate protein intake for adults living with diabetes. The research found that nearly half of US adults with diabetes did not meet the daily recommended protein intake, leading to greater physical limitations and potentially increasing the risk of muscle loss.
A Harvard study found that 20% of diabetes patients with high-deductible health plans reported skipping medications due to cost, compared to 16% in traditional plans. Patients with insulin reliance were 31% more likely to miss medication.
Researchers have identified a recurring trend of elevated blood glucose levels among those with severe Covid-19, which impairs lung immune defense and facilitates cytokine storm. Tight control and management of glycemia may be crucial for better outcomes, and metformin shows potential as a treatment option.
The American College of Cardiology has issued clinical guidance on reducing ASCVD risk in patients with persistent hypertriglyceridemia, recommending lifestyle intervention and non-statin therapies. The guidance emphasizes the importance of individualized nutrition guidance for these patients.
A recent study published in JAMA Internal Medicine investigated the association between cycling and mortality rates among individuals with diabetes. The research suggests that regular cycling may help reduce the risk of death from cardiovascular disease or any other cause.
A new study found that body mass index (BMI) is a risk factor for diabetes, but the optimal BMI threshold for screening varies significantly across low- and middle-income countries. The researchers analyzed data from over 680,000 people in 57 countries and found that individuals with a BMI of 23 kg/m2 or greater had an increased risk o...
Research suggests that antidepressant treatment can improve outcomes for individuals with comorbid diabetes and depression, reducing the risk of serious complications such as heart disease. Regular adherence to antidepressants is associated with better diabetes management and quality of life.
A new AI tool automatically measures fat around the heart from MRI scan images, linking it to increased diabetes risk. The tool was tested on over 45,000 people and accurately calculated their risk of developing diabetes.
Recent guidelines discourage routine aspirin use in adults 70 and older, but research suggests that older adults with diabetes may have potential overuse of aspirin therapy. If not actively discontinued, this could lead to unnecessary risks and side effects.
Researchers at Staffordshire University have developed a novel, low-cost method to detect foot ulcer risk without electronic sensors. This new technique uses 3D-printed structures to identify areas with high pressure, enabling clinicians to prescribe custom footwear or insoles.
Research reveals that people with frequent sleep problems are at a higher risk of dying than those without sleep problems. Specifically, individuals with Type-2 diabetes who also experience sleep disturbances face an increased mortality rate of 87%.
Only 5% of men and 9% of women meet daily fiber recommendations, associated with higher risks of heart disease and diabetes. Higher dietary fiber intake is strongly linked to reduced markers for heart and kidney disease in adults with diabetes.
Researchers investigated the effect of real-time continuous glucose monitoring on glycemic control among patients with insulin-treated diabetes. The study found that this technology improved blood sugar control, allowing for more effective management of the condition.
A healthy diet before and during pregnancy may reduce risks of gestational diabetes, high blood pressure disorders, and preterm birth. Women who followed healthier eating patterns had lower risks for these pregnancy complications.
A study by CNIC scientists found that glycosylated hemoglobin can identify individuals with advanced atherosclerotic disease and increased cardiovascular risk. The test can be used to calculate the degree of subclinical atherosclerosis in the general population, enabling personalized treatment plans.
A new study aims to identify diabetic donors whose corneas are suitable for transplant surgery, a crucial step in addressing growing demand for the procedure. The Diabetes Endothelial Keratoplasty Study will explore the impact of donor and recipient diabetes on outcomes and inform eye-banking and surgical practices.
A 23-year study found strong links between gestational diabetes during pregnancy and the development of type-1 and type-2 diabetes later in life. Women who experienced gestational diabetes were more prone to developing these conditions, highlighting the importance of autoantibody testing for risk assessment.
A global study found that nearly half a billion people with diabetes are not receiving comprehensive care, which can reduce health risks such as heart attacks, strokes, and nerve damage. The study highlights major gaps in specific care, including low cholesterol-lowering medication use.
A study suggests that pregnant women with gestational diabetes made only modest dietary changes, including a reduction in juice consumption and an increase in artificially sweetened beverages. Disparities were found in certain groups, such as Hispanic women and those with obesity or lower education levels.
Researchers found that sotagliflozin reduced the risk of death or worsening heart failure by 22-43% in patients with both diabetes and heart failure. The medication showed significant benefits across various patient subgroups, including those with preserved ejection fraction.
A University of Cincinnati researcher has found that plasma proteins discovered in the blood samples of diabetic patients who developed obstructive coronary disease may serve as biomarkers of severe heart blockage. This discovery could help patients with diabetes identify their risk and receive timely medical attention.
Researchers at UCSF have found a way to stimulate the natural surveillance system of immune cells to eliminate senescent cells, which contribute to aging and chronic diseases. This discovery offers an alternative to existing senolytic therapies and may lead to new treatments for age-related chronic diseases.
A systematic review of studies on telehealth and chronic conditions found that frequent services benefited patients more when continued for about a year. However, the optimal frequency and duration of telehealth services remain unknown. Researchers are working to measure dose in standard ways to inform best practices.
Researchers have developed a personalized sweat sensor that accurately estimates blood glucose levels without the need for finger pricks. The device uses a polyvinyl alcohol hydrogel and electrochemical sensors to measure glucose in sweat, providing an accurate estimate of blood sugar levels with an accuracy rate of over 95%.
A large clinical trial has definitively shown that dexamethasone, a steroid commonly used during anaesthesia before surgery, does not increase the risk of surgical wound infections. The study enrolled over 8,700 patients and found no significant difference in wound infection rates between those receiving dexamethasone and placebo.
A new study has identified risk factors for a severe course of COVID-19 in people with diabetes, including male sex, older age, high blood glucose levels, and existing comorbidities. Chronic metformin treatment was found to be associated with a reduced risk of severe COVID-19.
Researchers have discovered a compound found in some vegetables that may help reverse kidney problems associated with diabetes. Phenethyl isothiocyanate (PEITC) has been shown to target multiple pathways involved in diabetic nephropathy, including inflammation and oxidative status.
Researchers discovered that annual foot assessments can detect atrial fibrillation in patients with diabetes. The condition is found in approximately 17% of patients with diabetes, increasing stroke risk by five times.
A study found that addressing social determinants of health improved blood pressure control in patients with diabetes or hypertension in Kenya. The intervention combined community microfinance groups with group medical visits reduced systolic blood pressure by 44% compared to standard care.
Researchers are conducting a five-year longitudinal study to assess the non-pulmonary aspects of cystic fibrosis and identify barriers to healthy habits. The study aims to generate information on which patients are most likely to develop type 2 diabetes and how diet and exercise can reduce the risk.
A large study found that nearly 30% of patients with coronary artery disease have diabetes, significantly higher than the general population. Patients with heart disease and diabetes had worse outcomes, including a 38% higher risk of death during a five-year follow-up.
Researchers at The University of Tokyo have developed a novel cell therapy using a lotus-root-shaped device to transplant human pancreatic beta-cells in the long term. The device, called LENCON, was shown to successfully control blood glucose levels for over 180 days in diabetic mice.
Researchers found associations between lifestyle factors and COVID-19 infection risk, including maintaining healthy weight and high HDL cholesterol levels. These factors may help lower the risk of COVID-19 infection.
Researchers found persistent racial disparities in diabetes and high blood pressure-related mortality in rural areas, despite improvements in urban areas. Targeted public health and policy efforts are needed to address structural inequities contributing to these disparities.
A new study found that premature birth increases the risk of mortality in adulthood by up to 40% compared to full-term births. Chronic diseases such as heart disease and lung disease also pose a higher risk, with individuals born before 37 weeks having twice the risk of dying from these conditions.