Articles tagged with Diabetes
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent study published in Diabetologia found that COVID-19 patients with diabetes have a high risk of death and hospitalization, with 21% mortality rate. Factors such as age, treatment with metformin and insulin, and liver enzyme levels were associated with increased mortality risk.
A NIH study found that face masks increase humidity in inhaled air, which can benefit the immune system and combat respiratory diseases like COVID-19. The humidifying effects of masks vary depending on temperature and mask type, with thick cotton masks leading to the most increased level of humidity.
A recent observational study has found a significant association between prediabetes in older adults (ages 71-90) and the risk of progressing to diabetes. The study suggests that age is a key factor in determining the likelihood of disease progression.
Two studies shed light on the process of adding new fat cells, revealing a balance between existing fat cell expansion and new cell creation. A cancer drug can stimulate healthy fat cell formation, while inhibiting the development of new fat cells in one storage area can prevent diseases like diabetes and cardiovascular disease.
The grant will enable UVA Health to serve more underserved groups and rural communities with acute and chronic illnesses, improving patient outcomes and reducing barriers to care.
Researchers at Ohio State University discovered a new compound called BC1618 that blocks Fbxo48 and increases Ampk function, improving insulin responses in obese mice. The findings build on previous research to understand protein degradation and may lead to the development of a new class of diabetes drugs.
A recent study published in the Journal of Clinical Endocrinology & Metabolism highlights the need to address health disparities in diabetes by examining systemic racism and its impact on social conditions. The authors recommend implementing culturally and linguistically appropriate services, unconscious bias training, and value divers...
A CU Anschutz study reveals associations between placental signaling and metabolic disease in children and adults, offering potential early intervention and diagnosis of conditions like diabetes and cardiovascular disease. Placenta function can illuminate future disease in adults and children.
A small, highly controlled study at the National Institutes of Health compared the effects of a low-fat, plant-based diet to a low-carb, animal-based diet on calorie intake, hormone levels, body weight, and more. Participants lost weight on both diets, but only the low-fat diet led to a significant loss of body fat.
A recent study published in Nature Reviews Endocrinology highlights the interconnection between obesity, impaired metabolic health, and COVID-19 severity. The research found that obesity, visceral fatness, and impaired metabolic health are significant risk factors for a more severe course of COVID-19.
A new biomarker of insulin resistance tied to a 600 percent increase in risk of premature coronary heart disease has been discovered. Women under 55 with type-2 diabetes have a tenfold greater risk of having CHD over the next two decades, according to the study published in JAMA Cardiology.
A study analyzing ischemic stroke data from 8,900 patients reveals that female patients have higher crude mortality rates but equal survival rates after controlling for comorbidities. The researchers found no evidence of a sex disparity in stroke recurrence or composite outcomes.
Researchers at Ohio State University Wexner Medical Center and College of Medicine found no link between high doses of saccharin and the development of diabetes in healthy adults. The study isolated saccharin's effects on gut microbiome and metabolic profiles, showing no change in participants.
The Endocrine Society recommends government negotiation, greater transparency, and policy changes to reduce insulin costs. These policies aim to increase access to affordable insulin, particularly for low-income individuals and Medicare beneficiaries.
A recent study from the Buck Institute for Research on Aging reveals that tissue stiffness significantly impacts the innate immune system, contributing to the development of chronic diseases. The research suggests that cellular tension sets off an inflammatory loop, which may be targeted by new force-targeting immunotherapies.
Pregnant women who exercise more during the first trimester of pregnancy may have a lower risk of developing gestational diabetes. The analysis found that exercising at least 38 minutes per day lowers the risk of gestational diabetes by 2.1 cases per 100 women and abnormal blood sugar by 4.8 cases per 100 women.
Researchers improved understanding of intestinal stem cells' renewal and differentiation into specialized cell types. They identified a specific Wnt/planar cell polarity pathway regulating intestinal stem cell self-renewal and lineage decisions, crucial for treating diseases like diabetes and colorectal cancer.
A study published in Nature reveals that the thymus gland plays a crucial role in regulating the immune system and metabolic control during pregnancy. The researchers found that female sex hormones instruct changes in the thymus to produce specialized cells called Tregs, which help prevent miscarriage and gestational diabetes.
A research group at Graz University of Technology is developing an interactive and adaptive health information system that uses machine learning and cognitive psychology to provide personalized content. The system aims to improve doctor-patient communication, enhance health literacy, and make decisions beneficial to users' health.
A new drug combination combining a widely used diabetes treatment with an experimental cancer drug has shown significant improvements in blood glucose control and weight loss in mice. The combination treatment enhanced insulin secretion and reduced body weight, paving the way for clinical studies.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism uses machine learning to predict gestational diabetes in Chinese women. The researchers analyzed nearly 17,000 electronic health records and found that low body mass was associated with an increased risk of gestational diabetes.
A lipid metabolite called 12,13-diHOME is found in human breast milk and appears to be associated with beneficial infant weight gain and body composition. Maternal exercise may boost levels of the metabolite, potentially benefiting offspring growth and development.
Researchers at Temple University Health System develop improved models to predict 30-day readmission risk among patients with diabetes based on electronic health record data. The new tool, eDERRI TM, aims to accurately identify risk factors and improve care for vulnerable patients.
A standardized 'Artificial Pancreas (AP) Dashboard' is proposed to improve glycemic control and reduce hypoglycemia in insulin requiring patients with diabetes. The dashboard provides a single-page report of seven main components, including glucose metrics, insulin management, and user experience.
A study revealed that incretin-based drugs act on the Gq signaling pathway to promote insulin secretion and improve blood glucose levels in diabetic patients. The researchers found that a switch from Gs to Gq signaling occurs in pancreatic β-cells due to continuous cell excitation.
A new study finds that Medicaid expansion increases health insurance coverage, ability to see a physician, and foot examinations among patients with diabetes. However, it does not improve follow-up examinations, care, or treatment for diabetes, highlighting the need for additional structural changes.
Researchers discover anthraquinone-forming enzyme in plants, enabling mass production of plant-based medicines. The breakthrough could lead to more efficient and sustainable methods for producing these valuable compounds.
A recent study of over 11,000 hospital patients in Spain found that high blood sugar levels were associated with a higher chance of death from COVID-19. Patients with abnormally high glucose levels were more than twice as likely to die from the virus compared to those with normal readings.
High levels of GIP are linked to an increased risk of early arteriosclerosis signs, while GLP-1 is associated with a lower risk. The study suggests a potential link between raised GIP levels and cardiovascular disease in diabetic patients, highlighting the need for further investigation.
The Endocrine Society's virtual annual meeting, ENDO 2021, offers journalists the opportunity to discuss groundbreaking research with world-renowned experts in diverse fields. The event features over 70 live sessions, 20 oral sessions, and six plenaries, covering topics such as diabetes, obesity, reproductive health, and more.
Patients with chronic kidney disease can proactively manage their health by receiving tailored guidance on diet and lifestyle. Effective communication with doctors and strong family support are also crucial in empowering patients to take a more active role in their care. This study highlights the importance of clearer information, bett...
Researchers find that Staphylococcus aureus thrives in glucose-rich diabetic conditions, triggering virulent features and unchecked infection. Understanding this mechanism could lead to treatments targeting the bacteria's glucose hunger.
Potentially preventable hospitalizations among older adults are more common among Black and Hispanic Americans. Researchers found that increasing primary care access and affordable healthcare can reduce these hospitalizations.
A study found that weight and blood pressure were reduced regardless of when participants ate, challenging the idea that eating earlier affects energy usage. Researchers followed 41 overweight adults for 12 weeks and saw no difference in weight loss between those who ate most calories early or later.
A study using genome sequencing and CRISPR gene editing tools has uncovered a new biological pathway essential for insulin production in the YIPF5 gene. The research shows that genetic changes in this gene result in high stress levels, leading to cell death in insulin-producing cells.
Dr. Ann Marie Schmidt has made critical contributions to understanding the connections between heart disease and diabetes through her discovery of the RAGE receptor. Her work aims to develop targeted treatments for obesity and its complications, with the potential to impact hundreds of millions of lives worldwide.
A team of researchers from CNIO describes how the enterovirus coxsackievirus type B4 can induce diabetes by deregulating the URI protein and silencing the Pdx1 gene. This finding has potential implications for understanding the relationship between SARS-CoV-2 infection and diabetes.
The COVID-19 pandemic has accelerated adoption of innovative diabetes care models, including telehealth, to improve medical outcomes and patient experience. Despite challenges such as lack of insurance coverage and workforce shortages, these models have the potential to transform diabetes care for millions worldwide.
Researchers at University of Chicago Medicine are launching a four-year trial to test two interventions for personalized diabetes care in older adults. The 'My Diabetes, My Community' trial incorporates personalized sugar control goals, telephonic care management, and community-based resource access.
A new study has found that non-obese Vietnamese Americans are 60% more likely to have diabetes than non-obese, non-Hispanic White Americans. Only 9% of Vietnamese Americans with diabetes were obese, compared to half of all non-Hispanic White Americans.
A new study by Mount Sinai researchers found that a person's risk of uncontrolled chronic disease increases after moving to a place where the condition is more common. The study analyzed millions of adults who moved to new neighborhoods, counties, and states, tracing how their health changed after the move.
A new study found that continuous positive airway pressure (CPAP) treatment can lower daytime resting heart rates in patients with prediabetes who have obstructive sleep apnea, reducing their risk of cardiovascular disease. Optimal CPAP treatment also lowers heart rates during the day, similar to regular exercise.
Researchers found a strong correlation between glycoalbumin levels in tears and blood, suggesting potential for non-invasive diabetes monitoring. The study of 100 subjects with diabetes indicates that tear analysis could provide a reliable alternative to current invasive methods.
A prospective cohort study found that cycling was associated with lower all-cause and cardiovascular mortality risk among people with diabetes. The study analyzed data from over 7,500 adults and showed that even short periods of cycling per week can significantly reduce the risk of premature death.
This observational study found that preterm delivery, gestational diabetes, and low birth weight are associated with an increased risk of atherosclerotic cardiovascular disease in postmenopausal women. The study controlled for traditional risk factors, highlighting the importance of considering pregnancy outcomes in cardiovascular health.
Children born to mothers with gestational diabetes in pregnancy are at increased risk for accelerated aging and poor health outcomes later in life. The study found a link between epigenetic age and higher weight, body mass index, blood pressure, and cardiovascular risks.
Researchers estimate that diagnosing and treating high-risk cardiovascular conditions in England could prevent 3.4 million cases of heart disease and stroke, saving £68 billion over 25 years. Identifying undiagnosed diabetes would yield the greatest benefits, while following NICE guidelines would further increase health outcomes.
A study of 270 overweight women found no link between gut microbiota composition and the incidence of gestational diabetes. However, the combination of fish oil and probiotics was shown to modulate gut microbiota in women who did not develop gestational diabetes. Further research is needed to confirm these findings.
Researchers have identified 48 significant risk factors for mortality in diabetic patients discharged from hospital, grouped into nine categories. The most common risk factor is age, and co-morbidity burden and BMI are also significant, with heavier individuals at higher risk.
Researchers found that CNOT3 protein silences genes that cause insulin-producing cells to malfunction, leading to diabetes. Knocking out CNOT3 in mice results in the development of diabetes due to the activation of normally silenced genes.
A cardiac biomarker was found to have stronger associations with kidney disease progression than blood pressure in both diabetic and nondiabetic individuals. Higher levels of NTproBNP, urine NGAL, and troponin T were linked to increased rates of CKD progression.
Children born to obese mothers face higher risk of developing non-alcoholic fatty liver disease due to microbiome disruption, which can be influenced by maternal diet during pregnancy. The study aims to investigate the role of pyrroloquinoline quinone in improving the microbiome and lowering the risk for NAFLD.
A new Tulane University study found that patients hospitalized with COVID-19 who had metabolic syndrome were over three times more likely to die from the disease. The study also showed that patients with metabolic syndrome were nearly five times more likely to be admitted to an ICU, need a ventilator, or develop ARDS.
A study of over 86,000 Japanese couples found that wives with similar cardiovascular disease risk factors as their husbands are more likely to suffer from the same disorders. The researchers emphasize the importance of considering spouses' health in medical treatment and recommending family-based interventions.
Researchers found that women who deliver preterm or extremely preterm have a higher risk of dying from any cause, with 1.7-fold and 2.2-fold increased risks compared to full-term deliveries. The excess deaths associated with preterm delivery persist for up to 40 years after birth.
Researchers found that patients with diabetes and gout are at a higher risk of undergoing amputations compared to those without the conditions. The combined condition was associated with an amputation rate of 0.77 percent, significantly higher than the 0.03 percent in those without either disease.
Researchers found an association between recent weight loss and increased pancreatic cancer risk among individuals with diabetes, especially those with a longer duration of diabetes. The study suggests that maintaining weight loss may be crucial in reducing the risk of pancreatic cancer in people with diabetes.
Scientists have developed a protocol to measure mitochondrial activity in living animals using a bioluminescent molecule found in fireflies. This method reveals impaired mitochondrial functions in diseases such as diabetes and cancer.
Researchers develop a new mouse model of permanent neonatal diabetes using the Kuma mutation, which exhibits severe insulin-deficiency and beta-cell dysfunction in an immune deficient background. The study successfully reverses hyperglycemia with insulin implants, making it suitable for islet transplantation research.
Researchers at Children's Hospital of Philadelphia found that youth who are involved in the decision to start continuous glucose monitoring (CGM) are more likely to continue using the technology consistently. Having a role in the decision increases satisfaction and consistent use of CGM.