Articles tagged with Diabetes
A new study reveals that exercise training has opposite effects on muscle and fat tissues compared to high-fat diet-induced obesity. Exercise is found to down-regulate extracellular matrix-related pathways, while obesity up-regulates them. Conversely, exercise up-regulates circadian rhythm pathways, which are reversed by obesity. This ...
A randomized clinical trial found that time-restricted eating (TRE) is safe and feasible for 24-hour shift workers, improving glucose levels and blood pressure in those with cardiometabolic risk factors. Participants who followed a TRE pattern experienced improved quality of life and reduced bad cholesterol.
A clinical trial conducted by Salk Institute and UC San Diego Health found that time-restricted eating improved measures of health and wellbeing in firefighters. The study showed that a 10-hour eating window reduced VLDL cholesterol, improved mental health, and decreased alcohol intake.
Researchers have identified a previously unknown biological contributor to postpartum depression: impaired autophagy, which limits the body's ability to clean up old genetic material. This finding may lead to new treatments and early identification of women at risk before they become ill.
Research finds significant variation in obesity prevalence among Asian American subgroups, with health risks starting at lower BMIs. The study suggests using specific criteria for Asian populations to accurately assess obesity-related health risks.
A new study from Kaiser Permanente found that pregnant women with gestational diabetes who achieve rapid glucose control have better birth outcomes. The research analyzed data from over 26,000 patients and identified four trajectories of glucose control, with those starting out with optimal levels and maintaining it having the best res...
A mortality prediction model for older adults with dementia can guide discussions about financial resources, treatment preferences, and reduce unnecessary medical interventions. The model considers factors such as age, sex, body mass index, chronic conditions, and ability to perform daily activities.
A new study found that only around half of older adults with hypertension regularly check their blood pressure at home. Those who received a healthcare provider's recommendation to do so were three and a half times more likely to monitor their blood pressure regularly.
A new study found that placing a monthly cap on out-of-pocket costs for commercially insured patients could lower their highest monthly healthcare bills by 50-60%. A $500 monthly limit would affect about 25% of enrollees and reduce in-network OOP costs over a year by 46%, while a $250 limit would show a 51% reduction.
A scientific review found that cold water swimming can reduce 'bad' body fat and improve insulin sensitivity. However, the health benefits are uncertain due to limited study quality and variability in participant profiles.
Women with a history of gestational diabetes are at substantially higher risk of cardiovascular and cerebrovascular diseases, including coronary artery disease, heart attack, and stroke. Continuous monitoring is crucial to mitigate these risks.
Researchers at Washington State University identified eight proteins that regulate insulin sensitivity and resistance in hibernating bears, similar to human genes. The discovery could lead to the development of treatments for human diabetes.
The presentation discusses how climate change affects diabetes care and emphasizes the need for a green transition to reduce healthcare's environmental footprint. Reducing environmental impact can also improve health outcomes, according to Dr. Fiona Adshead.
A new study from Michigan Medicine found that adults with more chronic health conditions are at higher risk of serious financial problems, including late payments, poor credit scores, and bankruptcy. The study analyzed nearly 3 million privately insured adults and found that those with seven or more chronic conditions had three to four...
The need to reduce diabetes care product waste is a pressing issue, with disposable devices generating enormous amounts of plastic. Experts, including Professor Lutz Heinemann, are exploring strategies to increase recycling and sustainability in the industry.
Research at Karolinska Institutet shows that people with diabetes have lower levels of psoriasin, a key peptide that weakens the bladder's protective barrier function. This increases the risk of urinary tract infections. Oestrogen therapy may help regulate the immune response to UTIs in patients with diabetes.
A study by researchers from UTHealth Houston and the University of Miami found that adolescents with severe obesity who underwent bariatric surgery before age 22 lost significant weight and experienced complete remission of comorbidities such as diabetes, asthma, and elevated lipids. The study's results show that these young patients c...
A randomized clinical trial found that protein restriction diets can lead to weight loss, improved blood sugar and lipid levels, and controlled blood pressure. The study involved 21 patients with metabolic syndrome, who were given either a calorie or protein restriction diet for 27 days.
A Brazilian study analyzed risk factors for heart attacks and found that high blood sugar had the most significant impact on mortality. Reducing smoking prevented most deaths from cardiovascular disease, while lowering diabetes incidence could have saved up to 5,000 lives over a decade.
Researchers found that using race-free creatinine formula helps equalize access for Black and white patients. The study showed that among 350 Black patients, kidney failure was reached at an average 23 months, versus an average 22 months for 122 white patients.
A new day-case surgical procedure for diabetic foot ulcers has been shown to accelerate effective healing, reduce recurrence, and prevent amputations. The procedure, which involves adjusting the mechanics of the foot, was found to be effective in treating up to 19 patients with successful ulcer resolution in just 3-4 weeks.
For seven years after bariatric surgery, participants showed clinically important improvements in pain levels, physical function, and work productivity, with some backsliding over time. The study found durable effects on walking speed, fitness, and most metrics of pain, even among older adults.
A large study found that tighter gestational diabetes control reduced serious health problems and deaths in newborns, while increasing health risks for mothers. However, the exact causes of these increased risks remain unexplained, highlighting the need for further research.
People with diabetes face higher risk of hospitalization during extreme heat events due to dehydration and blood glucose imbalance. Research reveals a link between extreme heat and emergency hospitalizations for hypo- and hyperglycemia-related conditions.
Children born to mothers with gestational diabetes and obesity are twice as likely to develop attention-deficit/hyperactivity disorder (ADHD), according to a new study. The researchers found that excessive weight gain during pregnancy was a significant risk factor for ADHD in offspring, but not within normal weight gain ranges.
Researchers at Washington University in St. Louis are developing a new wound dressing to overcome obstacles to healing in people with diabetes, including chronic inflammation and delayed growth of new blood vessels.
A new study found that tighter blood sugar control for women with gestational diabetes reduced infant death, trauma, and shoulder dystocia by half. However, it also increased the risk of serious health complications for the mother, such as major postpartum hemorrhage.
A small qualitative study found that emergency departments often fail to provide dignified and respectful care to frail older patients, leading to long waits and poor communication. The researchers recommend making healthcare settings more 'frailty friendly' by prioritizing patient comfort and involvement.
Researchers at Washington University have developed a hydrogel system that preserves biochemistry and mechanical environments of cultured podocyte cells. This allows researchers to identify new ways to control mechanisms used by cells to heal themselves, potentially leading to therapies for currently incurable diseases.
Researchers at CeMM have discovered that targeting SMNDC1 in alpha cells can induce insulin production, a potential new approach for treating diabetes. The study identified a key molecular mechanism regulating insulin hormone production and its essential role in the treatment of diabetes.
Researchers at the University of British Columbia have made a breakthrough in developing an oral insulin tablet that is absorbed by the body in the same way as injected insulin. The tablet is designed to dissolve when placed between the gum and cheek, releasing all the insulin into the liver without wasting or decomposing it.
The study found that the probability of surviving cardiac arrest outside hospital has more than doubled in 30 years, from approximately 5% to 11%. The improvement is attributed to increased CPR training and better healthcare resources. However, ambulance delays and an increase in difficult-to-treat cases are hindering further progress.
A new map of brain stem circuits controlling eating behavior could lead to better obesity treatments. The atlas, built from recent discoveries in mice and human studies, identifies two food intake-suppressing circuits in the brain stem, one causing nausea and another not.
A new international study suggests that dog owners who spend more time exercising themselves tend to exercise their dogs more, leading to a perceived ideal body weight. The study found that feeding practices play a main role in owner perception of their dog being overweight, while exercise practices are crucial for an ideal weight.
The USPSTF recommends prescribing statins for adults aged 40-75 with one or more CVD risk factors and estimated 10-year CVD risk of 10% or greater. For those aged 76 or older, the evidence is insufficient to make a recommendation. Statin use can significantly reduce CVD events and mortality in this population.
A new home-based test, aAP, allows patients to monitor their autonomic responses and make lifestyle changes to alleviate symptoms. This test reduces NHS resource demand and provides clinicians with valuable insights into patient triggers.
A study of over 4,000 pregnant women in New Zealand found that lowering the blood-sugar threshold for diagnosis can improve health outcomes for mothers and babies. Women diagnosed with gestational diabetes using a lower threshold were more likely to receive treatment and use healthcare services.
Mutations in EnhP disrupt a non-protein coding gene, causing pancreatic malformations and diabetes. The study sheds light on the hierarchical operation of enhancers in gene regulation.
A large, randomized trial found that metformin reduced serious COVID-19 outcomes by more than half in high-risk patients when started early. The study compared three medications and provided valuable insights into their effects on COVID-19.
The study found that metformin lowers the odds of emergency department visits, hospitalizations, or death due to COVID-19 by over 40 percent. Metformin also showed a significant reduction in serious outcomes when prescribed early in the onset of symptoms.
Researchers developed a method combining musical tests with EEG measurement to detect cognitive decline in old age. The study tested 50 elderly people who scored low on the mini-mental test, showing promising results in detecting mental deterioration.
A West Virginia University study explores the link between pregnancy, sedentary behavior, and cardiovascular disease risk in women. The research aims to investigate whether physical activity can reduce or eliminate this accelerated risk development in women.
A national study by UC San Francisco found that basic home blood pressure cuffs and smartphone-connected devices have no significant difference in improving blood pressure control. After six months, patients who used basic cuffs had a lower blood pressure reduction compared to those using Bluetooth-enabled devices.
A new study published in Diabetes Care has reported an increase in health inequalities among ethnic minorities with diabetes since the COVID-19 pandemic. The review highlighted structural barriers such as housing, education, and employment opportunities that put these individuals at greater risk of severe COVID-19 outcomes.
Higher aldosterone concentrations are associated with lower eGFR, lower potassium levels in blood, and higher potassium and protein concentrations in urine. The risk of CKD worsening was independent of diabetes status. Finerenone may help prevent CKD progression by targeting aldosterone's action.
Researchers found that endothelial cells in blood vessels drive the body's metabolism and produce nitrous oxide to regulate brown fat production. This discovery reverses long-held ideas about the relationship between diabetes, fat and cardiovascular disease.
A Swedish study of over 4,000 adults found that those with high prostasin blood levels were 76% more likely to develop diabetes and 43% more likely to die from cancer. Prostasin may be an indicator of disease occurrence or causally relevant, raising the possibility of targeting this protein for future treatments.
Researchers successfully engineered E. coli collected from human and mice gut microbiomes, showing potential to treat diseases such as diabetes. The engineered bacteria retain their activity for the entire lifetime of the host and positively influence diabetes progression in mice.
A new light-based sensor harnesses the light-guiding properties of spider silk to detect and measure small changes in the refractive index of a biological solution, including glucose and other types of sugar solutions. The sensor is practical, compact, biocompatible, cost-effective, and highly sensitive.
New research finds junk food advertising restrictions have prevented 94,867 fewer obesity cases, 2,857 fewer diabetes cases, and 1,915 fewer cardiovascular disease cases. The policy is estimated to save the NHS £218 million over its lifetime.
Individualized, comprehensive treatment approaches and risk stratification of patients are crucial for effective treatment of MAFLD. Lifestyle modifications and pharmaceutical therapeutics combining to treat the condition.
A new study found that a fast food diet before pregnancy can negatively impact breast milk quality and baby's health, increasing the risk of conditions like heart disease and diabetes. Even short-term consumption of high sugar and fat diets affects women's health and fertility.
Adults with chronic kidney disease are more likely to have a low intake of fruits and vegetables compared to similar individuals without the condition. This study suggests that increasing fruit and vegetable consumption may be beneficial for overall health.
A pooled data analysis of 11 international studies found that NAFLD is associated with a 50% heightened risk of developing heart failure. The severity of NAFLD also increases the risk, especially with extensive liver fibrosis.
Artificial neural networks use white matter cracks and cerebral cortex furrows to estimate biological age, which can indicate possible disease or injury. The 'black box' problem has been solved, revealing the algorithm's decision-making process.
Researchers have found that infusing glucagon-like peptide-1 (GLP-1) hormone can improve impaired islet cell function in the pancreas of cystic fibrosis patients, potentially improving blood sugar control and treatment burden. The study suggests a new therapeutic approach for treating cystic fibrosis-related diabetes.
A new study found that COVID-19 patients are at a higher risk of developing cardiovascular diseases and diabetes in the months following infection. The risk of diabetes returns to baseline levels within 23 weeks, while cardiovascular disease risk decreases after 7 weeks.
A study found that men in Alberta, Canada are not getting tested for diabetes often enough, particularly in their 40s. This could lead to serious complications like heart disease and cancer later in life. The researchers recommend that everyone over 40 get screened for diabetes every three years.
A new study published in Neurobiology of Sleep and Circadian Rhythms found that shift work can lead to long-lasting health effects, including increased severity of strokes. The research, led by Texas A&M University, suggests that disrupted internal body clocks can alter gut and brain interactions, leading to worse stroke outcomes.
A new Mount Sinai study reveals that young Black adults are twice as likely to have atherosclerosis as their Hispanic counterparts. Researchers used comprehensive questionnaires and 3D vascular ultrasounds to determine cardiovascular risk scores, finding significant discrepancies between the groups.