Articles tagged with Diabetes
A UCSF study suggests people who identify as lesbian, gay, bisexual, transgender, or non-binary may have a higher risk of stroke at a younger age. Non-traditional stroke risks include HIV and syphilis infections.
An international study led by the University of Trento revealed that social interactions play a key role in shaping the composition of our microbiomes. The researchers found that adults acquire microbes through close contact with family members, partners, and friends, while infants acquire them later on at birth.
Researchers have developed an orally administered tablet powered by chemical micromotors that deliver insulin to the colon, reducing blood glucose levels for over five hours. The mini-tablets protected from stomach acid and used hydrogen gas bubbles as micromotors to propel insulin into the bloodstream.
Researchers found that exercise induces a cycle of fatigue and recovery in muscles, paralleled by mitochondrial network rebuilding. Long-term training programs improved middle-aged fitness, while AMPK interventions enhanced exercise capacity during aging.
Researchers at Salk Institute discover thousands of previously unknown microproteins in brown and white fat tissue, finding that one, Gm8773, increases feeding activity in mice. This discovery could lead to the development of a therapeutic to promote weight gain in certain disease situations.
Researchers found that time-restricted eating synchronizes circadian rhythms across multiple systems in mice, activating genes involved in specific diseases like cancer. Nearly 40% of genes in the adrenal gland and pancreas were affected by time-restricted eating, offering guidance for managing diseases.
A study published in Diabetes Research and Clinical Practice found that women with diabetes mellitus are at a higher risk of venous thromboembolism (VTE) than men, particularly during perimenopause. The risk is 1.52 times higher for women with DM compared to those without DM.
Scientists discover a way to train healthy immune cells to acquire tumor cells' skills for accelerating diabetic wound healing. TAMs-educated macrophages promote cell proliferation, resolve inflammation and orchestrate vasculature.
Researchers discovered that MODY3 patients experience hypersecretion of insulin from β cells due to more efficient membrane depolarization. This phenomenon precedes pancreatic β cell failure and can be targeted for prevention or delay with treatments, such as diets or drugs.
A UMass Amherst study reveals that 61% of wellness visits for reproductive-age women (15-49) were with OB-GYNs, while chronic condition patients also relied heavily on these specialists. Key preventive services like pap tests and pelvic exams were more common in OB-GYN settings, whereas lipid testing was rare.
Over three decades, glycemic control stagnated among US adults with diabetes, exacerbating racial and ethnic disparities. Improved insulin access may optimize glycemic control and reduce disparities in this population.
Researchers found that high-performing practices used proactive approaches to organize staff and manage patient interactions, leading to comprehensive addressing of patient care needs during in-person visits. The study suggests incorporating proactive patient care processes into primary care delivery to improve diabetes outcomes.
Researchers at Osaka University found that disasters and pandemics increase major non-communicable diseases and mental disorders, especially among certain age groups. The study highlights the need for improved post-disaster health policies and prevention strategies to mitigate these effects.
A new study finds that inadequate pollination leads to a 3-5% loss of fruit, vegetable, and nut production, resulting in 427,000 excess deaths annually from lost healthy food consumption. The health burden is greater in middle- and higher-income countries with high rates of non-communicable diseases.
Females with more subcutaneous fat are protected against brain inflammation, a risk factor for dementia and stroke. Removing subcutaneous fat increases brain inflammation in females, even on low-fat diets.
WEHI researchers have visualized how a non-insulin molecule can mimic the role of insulin, opening new avenues for an oral insulin pill. The study confirms alternative molecules can be used to turn on blood glucose uptake, bypassing insulin needs.
A retrospective cohort study of 1,404 subjects with type 2 diabetes found that metformin use reduced the risk of delirium by 50% and decreased 3-year mortality rates. The study suggests that metformin may be a potential benefit for patients with diabetes, particularly in reducing age-related disorders such as dementia.
Researchers found that P2-HNF4α expression is associated with p-STAT3 and c-Myc expression in NAFLD patients, suggesting potential biomarkers for hepatocellular carcinoma (HCC) risk. Additionally, p-STAT3 expression was linked to hypertension, while c-Myc expression was associated with advanced fibrosis.
A study aims to enhance accessibility and value of health information tools for older adults with both diabetes and Alzheimer's disease. The research focuses on developing a user-friendly technology to detect low blood sugar, which can cause dizziness, confusion, and even death.
A study suggests that visceral fat cells, rather than subcutaneous fat cells, are more susceptible to infection by the COVID-19 virus. This increased susceptibility leads to a higher viral load and production of pro-inflammatory cytokines, which can exacerbate severe disease.
Researchers analyzed data from over 80,000 primary care physicians and found no clear connection between MIPS scores and clinical performance. Doctors with low MIPS scores performed worse on some process measures but better on others, suggesting that the system may prioritize paperwork over patient outcomes.
Researchers developed an app to track CPAP use, sleep patterns, and other health metrics to provide a new adherence metric that aligns therapy with individual need. This tool can help patients and providers deliver more effective sleep apnea treatment by tracking progress toward a personalized dose of therapy.
A recent study published in Geriatrics found that age, education, social network, pain, and depression are significant predictors of physical activity in older adults. The findings suggest that modifying these factors through targeted interventions can increase physical activity levels.
A recent study led by the University of Nevada, Reno and the Pan American Health Organization suggests that the adoption of front-of-pack nutrition labeling can help reduce poor-nutrition related non-communicable diseases in the region. Improved FOPNL systems have been associated with improved diet quality and reduced risk of NCDs.
A new serological test, PepSeq, allows scientists to quickly test antibody binding against hundreds of thousands of protein targets, helping prepare for and respond to pandemics. The technology identifies specific antibodies that provide protection against infection, holding promise for developing effective vaccines and treatments.
A new study suggests that human retinal endothelial cells have a protective system against hyperglycemia, which delays the onset of diabetic retinopathy. Prolonged exposure to high glucose actually promotes cell recovery and resistance to damage.
The EPCD model, leveraging care team nurses, pharmacists, and social workers, improved diabetes care quality by increasing patients' adherence to treatment guidelines. Staff clinician practices saw significant improvements in glycemic control and patient outcomes after EPCD implementation.
Primary care clinicians are more likely to prescribe CGM when closer to specialized endocrinologists and serving more Medicare patients. Expanded insurance coverage and consultation on CGM issues can support increased use of the technology.
A recent clinical trial found that the Green Mediterranean diet reduced visceral adipose tissue by 14%, outperforming both the traditional Mediterranean diet and a healthy diet. The new diet incorporates dietary polyphenols and lower red meat intake, resulting in significant weight loss benefits.
Researchers at UNIST developed a subcutaneously implantable electromagnetic biosensor system for continuous glucose monitoring. The new technology eliminates the need for frequent finger pricking, providing more accurate blood glucose level tracking and improved patient care.
The UC San Diego Alpha Stem Cell Clinic will receive $8 million in funding to launch new clinical trials and improve accessibility of stem cell therapies. The clinic has already launched 59 clinical trials and treated 277 patients with various diseases.
A new study from the University of South Australia found that eating 30-50 grams of almonds can help people cut back on kilojoules consumed each day. This leads to a reduced energy intake by 300 kilojoules, mostly coming from junk food.
A UCF researcher is studying the potential long-term effects of COVID-19 on people with diabetes, including how it can advance their risk for heart disease and other complications. Dr. Singla believes that COVID-19 can alter a person's genetic makeup, leading to enhanced proliferation of disease.
Researchers found that a genetic mutation associated with liver disease confers different levels of risk depending on a patient's diabetic status. In diabetic patients, the mutation predisposes them to nonalcoholic fatty liver disease, but in nondiabetic patients, it protects against liver disease.
A new study published in the Journal of Clinical Endocrinology & Metabolism reveals that pancreas transplantation can provide up to 90% of recipients with diabetes freedom from insulin therapy and glucose monitoring. Despite high success rates, transplant numbers have declined due to lack of consensus criteria, education, and resource ...
A new study found that exposure to outdoor artificial light at night is associated with impaired blood glucose control and an increased risk of diabetes. Chronic exposure to residential outdoor LAN was positively associated with blood glucose levels, insulin resistance and diabetes prevalence.
Research at Tel Aviv University found that high-intensity aerobic exercise increases glucose consumption in internal organs, reducing energy availability for tumors. The study reduced the risk of metastatic cancer in humans and animal models by up to 72%.
Research recognizes significant association between unhealthy behaviors and conditions like obesity, diabetes, smoking, leading to poorer COVID-19 outcomes. Experts emphasize promoting healthy lifestyles to combat syndemics, particularly impacting underserved communities.
Researchers have created a chemical tag that can be added to drugs, allowing them to enter blood circulation via the intestines. The tag, called EPP6, is a neutral peptide that can deliver drugs orally, potentially replacing injections for diabetes and cancer patients.
Researchers at Osaka University identified T-cadherin as a factor that feeds back a lack of insulin to pancreatic β cells, inducing their proliferation. This finding suggests a potential new treatment for diabetes by targeting T-cadherin.
A team at the University of Exeter has found genetic changes in a region that controls the activity of the genome, turning on or off genes, which led to the discovery of the cause of Congenital Hyperinsulinism. This breakthrough could unlock new causes of rare diseases and pave the way for improved treatments.
A new comprehensive guideline, C-CHANGE, offers 83 actionable recommendations to prevent and treat cardiovascular disease in Canadian adults. The updated resource incorporates new or revised recommendations from 11 guideline groups, addressing key risk factors such as dietary habits, smoking, and physical activity.
Researchers at the University of Houston are developing a clinical decision support system to predict which patients with diabetes are most likely to experience complications. The tool, called Primary Care Forecast, uses deep learning to consider patient health history and social factors such as employment status and education level.
Researchers have discovered a way to reactivate a fetal repair pathway in adults to improve healing of diabetic wounds. The study used tissue nanotransfection technology to deliver a gene that activates the protein NPGPx, which is active in fetuses but largely inactive in adults and absent in diabetic adults.
A UMass Amherst epidemiologist is investigating how physical and mental health during pregnancy can predict cardiovascular and mental health disorders in middle age. Pregnancy complications may be associated with poorer cardiometabolic health and mental health status in middle adulthood among Puerto Rican women.
A study published in the New England Journal of Medicine found that new onset CKD rates are higher among Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations compared to white persons with diabetes. The rate declined from 8% in 2015-2016 to 6.4% in 2019-2020.
The $2.4 million grant will provide direct training for new community health workers in Lubbock and throughout the state through registered apprenticeship programs and job placements. The program aims to increase access to healthcare and address public health needs for underserved communities.
A study found that the HASTER lncRNA promoter regulates the activity of the HNF1A gene, which causes diabetes. This discovery paves the way for new therapeutic strategies by manipulating this regulatory element.
Researchers found that male mice were three times more likely to survive E. coli infection due to sex-biased lipid metabolism, which may hold risks for males in today's high-calorie environment. The study identified a signaling pathway regulating lipids and growth hormone as potential therapeutic targets for fatty liver disease.
Research at Northwestern University finds that eating during the daytime is ideal for dissipating energy as heat, while nighttime eating disrupts this process. This study's findings have broad implications for dieting, sleep loss, and patient nutrition, particularly in cases of Type II Diabetes.
The American Gastroenterological Association releases new guidelines recommending medications paired with lifestyle changes for adults struggling to lose weight. The guidelines highlight the importance of treating obesity as a biological disease, reducing health complications like diabetes and fatty liver.
A study of over two million individuals in Denmark found that mothers with hypertensive disorder of pregnancy have a higher mortality risk in their offspring. The study shows an association between maternal HDP and various cause-specific deaths, including cardiovascular disease and cancer.
A study published in Diabetes Care found that trigger finger is more prevalent among individuals with diabetes, particularly those with poorly regulated blood sugar. The risk of trigger finger increases with poor HbA1C levels, highlighting the potential link between blood sugar dysregulation and this condition.
A new study found that sleeping five hours or less per night is associated with a higher risk of developing at least two chronic diseases over a 25-year period. This includes heart disease, cancer, and diabetes. The study analyzed data from over 7,000 men and women aged 50, 60, and 70.
A global study found that cardiovascular disease risk factors are largely the same for men and women, except for high LDL levels which affect men more. Women have a lower risk of heart attack and stroke due to their estrogen's effect on vessel walls and liver function.
A national study found that patients with cardiovascular disease had a higher mortality rate than those without, but this association was largely due to shared risk factors. Myocardial injury was common among critically ill COVID-19 patients and associated with poor outcomes.
A study reveals a high incidence of chronic kidney disease among adults with diabetes, particularly affecting Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino(a) groups. The rate of new onset CKD was higher in these groups by approximately 60%, 40%, 33%, and 25% compared to White persons with ...
Researchers found that metformin targeted 30 genes associated with atrial fibrillation, showing direct effects on gene expression for eight. The study suggests metformin may be a promising candidate for treating atrial fibrillation due to its potential to reduce the risk of complications such as stroke and heart failure.
The joint consensus report provides a review of current AID systems, discussing benefits, limitations, safety, and regulatory pathways. The report aims to encourage ongoing improvement of this technology, making it safe and accessible for all who can benefit from it.
Researchers at FAU's Schmidt College of Medicine are developing a pilot program to tackle health disparities by leveraging electronic health records, artificial intelligence, and machine learning. The project aims to improve AI/ML delivery and research operations in community health centers and federally qualified health centers.