Articles tagged with Diabetes
A study by University of Toronto researchers found that childhood physical abuse is associated with chronic pain, diabetes, cancer, migraines, arthritis, and heart disease in later life. The trauma can influence both physical and mental health many decades after the event.
A long-term high-fat diet has been shown to cause significant weight gain and metabolic disorders in mice, leading to anxiety, depression, and worsening Alzheimer's disease. The study suggests a clear link between chronic obesity and diabetes with cognitive decline.
Researchers found that factory-calibrated continuous glucose monitors are sufficiently accurate for estimating blood-sugar levels in patients with end-stage renal disease on hemodialysis. The devices showed 'clinical reliability', with almost 99% of readings accurate enough to be used without confirmatory fingerstick blood sugar readings.
Researchers at Joslin Diabetes Center and Brigham and Women's Hospital found that cold exposure can resolve obesity-induced inflammation while improving insulin sensitivity and glucose tolerance in diet-induced obese mice. Brown adipose tissue is activated to produce anti-inflammatory molecules, including Maresin 2.
A study of 552 older adults found that those exposed to light during sleep were significantly more likely to develop obesity, high blood pressure and diabetes. The study suggests that minimizing light exposure at night can help prevent these conditions.
A recent study at Tokyo Institute of Technology reveals that dopamine regulates insulin secretion through a complex of receptors, specifically D1 and D2. The discovery offers new insights into the mechanism behind this regulation and has potential therapeutic targets for preventing, treating, and managing diabetes.
Researchers describe a mechanism by which inhibitory neurons in a specific brain region suppress nausea-causing excitatory neurons. Activating these inhibitory neurons with the chemical messenger GIP eliminates nausea behaviors in mice, offering an alternative approach to reducing nausea.
Chronic kidney disease and glaucoma have been found to share common risk factors such as diabetes and hypertension, leading to a higher risk of developing both conditions. The study also reveals that patients with glaucoma are more likely to develop chronic kidney disease over time.
Researchers have discovered the process of incorporating selenium into 25 specialized proteins, essential for various cellular and metabolic processes. The study provides critical insights into the workings of these vital mechanisms, which could lead to the development of new medical therapies.
Researchers at Beth Israel Deaconess Medical Center have identified a key enzyme involved in producing a new class of lipids with therapeutic effects for patients with diabetes. The discovery, published in Nature, could pave the way for new treatments to protect insulin-producing cells and improve blood sugar control.
A study published in Alzheimer's & Dementia found that individuals with at least two cardiometabolic diseases, such as type 2 diabetes and heart disease, double their risk of developing dementia. The study suggests that prevention of these diseases could be a strategy for reducing dementia risk.
Patients with diabetes who participate in a free Annual Wellness Visit are 36% less likely to need an amputation, according to a new study from the University of Virginia School of Medicine. This preventive care service helps detect foot complications earlier, reducing the risk of amputations.
Researchers discovered that uncontrolled diabetes increases heart failure risk by 1.5 to 1.8 times in preclinical stages A and B. Early diabetes control can prevent progression to overt heart failure, suggesting a potential lifesaving strategy.
Researchers investigated how COVID-19 affected breastfeeding practices, finding some mothers experienced improved bonding with their babies during stay-at-home orders. Food insecurity was linked to higher diabetes distress among adults with pre-diabetes or diabetes. The studies also found that technology access was crucial for older ad...
Researchers have developed unique self-regulating footwear for persons with diabetes, featuring snapping mechanisms that distribute pressure evenly. The sandals can be customized to an individual's foot dimensions and walking style, promoting faster healing of injured regions and preventing further injuries.
A recent study found that older adults in later-born generations are more likely to have multiple chronic health conditions than prior generations. This trend may lead to increased strain on the well-being of older adults and medical insurance systems, particularly as the US population ages. The researchers suggest that sociodemographi...
Researchers at Karolinska Institutet describe a new way of generating insulin-producing cells using a molecule that stimulates protein synthesis and boosts insulin production. The study shows promise for treating type 1 and 2 diabetes, potentially increasing the number of insulin-producing pancreatic β cells.
Scientists at CNIC discovered a complex network between liver tissue connections that allows the liver to regulate body temperature. The secretion of IL-12 by liver-infiltrating macrophages blocks FGF21 production, reducing heat generation by brown fat in mice.
Research in western Amazonia found that at least 150 minutes of exercise per week correlated with lower birth weight and reduced risk of childhood obesity and diabetes. The study also showed that physical activity during pregnancy may help prevent excessive weight gain, contributing to a reduced birth weight.
A new study found a strong association between prediabetes and an increased risk of heart attacks, with patients having prediabetes being 25% more likely to experience a heart attack. The researchers also discovered that those with prediabetes were at higher odds for requiring percutaneous intervention and heart bypass surgery.
A customized WeightWatchers program has been shown to effectively manage Type 2 diabetes by lowering blood glucose levels and promoting significant weight loss. Participants in the six-month clinical trial experienced improved glycemic control and overall well-being, with clinically meaningful and statistically significant results.
A new study finds that cancer patients are at a greater risk of developing diabetes, particularly those with lung, pancreatic, breast, brain, urinary tract, or uterine cancers. The study also shows that cancer patients who develop diabetes die sooner than survivors without diabetes.
Researchers at Karolinska Institutet found a link between genetic variants in diabetes drug targets and lower Alzheimer's disease risk. The study suggests that the target protein, KATP channel, may be a therapeutic target for treating and preventing Alzheimer's disease.
A study published in Frontiers in Nutrition found that malnutrition contributes to sarcopenia in hemodialysis patients, characterized by muscle mass, strength, and function losses. The Nutrition Risk Index (NRI) is a simple and convenient metric developed in Japan, which shows significant relationships between NRI score and sarcopenia,...
Research describes how breast cancer cells impair pancreatic islet function to suppress insulin production, leading to diabetes and increased tumor growth. The study identifies microRNA-122 as a key player in this process.
This study conducted within an existing community-based COVID-19 testing program successfully integrated rapid diabetes screening, reaching low-income Latinx individuals who were mostly undiagnosed with prediabetes and diabetes. The results highlight the importance of addressing health disparities in underserved populations.
A team of engineers is working on a novel treatment using nanoparticles carrying therapeutic proteins to promote regeneration of blood vessels and muscle in injured limbs. The approach, which has shown promising results in animal models, aims to treat critical limb ischemia, a condition that can lead to amputation or death.
The Endocrine Society's ENDO 2022 news conferences will showcase the latest research on diabetes, obesity, thyroid health, and reproductive conditions. Key findings include the impact of chemicals in hair care products on breast cancer cells and the effects of childhood obesity on male infertility.
New data analyses from RedHill's Talicia H. pylori eradication clinical trials program showed high eradication rates and favorable safety and efficacy profiles in patients with diabetes. The study found that Talicia maintained high eradication rates of 91.7% and 84.1% in patients with and without diabetes, respectively.
A new systematic review and meta-analysis published in The BMJ provides a comprehensive understanding of the adverse outcomes associated with gestational diabetes mellitus during pregnancy. The study found that women with gestational diabetes had increased odds of caesarean section, preterm delivery, and infant complications.
A retrospective cohort study found that poor continuity of care is associated with increased health care use and sub-optimal prescribing of guideline-recommended medications in patients with CKD. Strengthening patient-provider relationships and guiding physicians on recommended prescribing can help mitigate these issues.
A study found that general practitioners use ultrasound for exploratory purposes, outside of formal training areas, raising concerns about appropriate use and scanning competency. Meanwhile, lung ultrasounds may enable primary care physicians to prescribe antibiotics directly, reducing radiation exposure and saving time.
A systematic review of qualitative studies found that rural patients experience significant challenges in accessing health care services for chronic conditions. Cultural, structural, and individual factors influence these experiences, highlighting the need for culturally appropriate interventions to improve access to care.
The five-year DIASIRE summer program will accept eight to 10 undergraduate students from across the country, providing them with valuable research skills and mentorship from OHIO faculty. Students will learn about the history and pathophysiology of diabetes, as well as epidemiological, social, and molecular/cellular research efforts.
A review of 38 randomized controlled trials found that counseling patients about contraceptive use and providing contraceptives increases use without increasing STI risk or reducing condom use. The interventions also decrease unintended pregnancy in trials designed to evaluate this outcome.
A new international study has identified the most critical vascular risk factors for dementia, highlighting the importance of controlling high blood pressure and diabetes. The research, led by Professor Emer McGrath, found that individuals with these conditions are four times more likely to develop dementia than those without them.
A new analysis from the NACMI registry found that STEMI patients with COVID-19 have a significant increased risk of in-hospital mortality compared to pre-pandemic levels. Clinical characteristics and treatment strategies differ between men and women, highlighting the need for continued research into cardiovascular health impacts of COV...
The USPSTF and ADA now recommend screening adults as young as 35 for diabetes. A new study estimates the proportion of asymptomatic adults who are eligible for screening based on these guidelines, particularly among those with prediabetes or undiagnosed diabetes.
Researchers and academics from the UK and Germany come together to discuss therapeutic footwear for people with diabetes. The workshop aims to establish new research links and develop research capacity to improve the lives of those affected.
A new study found that lean individuals with non-alcoholic fatty liver disease (NAFLD) have a higher prevalence of cardiovascular disease compared to those who are overweight or obese. Despite having lower risks for other metabolic and cardiovascular conditions, lean patients with NAFLD were more likely to develop cardiovascular disease.
Researchers created human mini-kidneys that mimic diabetic kidneys, finding increased susceptibility to SARS-CoV-2 infection and a critical role for the ACE2 receptor. The study provides new insights into the link between diabetes and COVID-19 disease.
Researchers studied cavefish genome-wide map of liver tissue to understand metabolism evolution and its potential applications for humans. The study found striking similarities in metabolic adaptations among cavefish populations, raising questions about universal adaptation mechanisms that could be triggered in other species like humans.
A recent study found that obesity, impaired blood glucose metabolism, and high blood pressure significantly increase the risk of dying from COVID-19 in young and middle-aged people. Researchers analyzed data from the European case registry LEOSS and found that patients with all three conditions had a similar increased risk of death as ...
A new meta-analysis suggests that a healthy diet during pregnancy does not significantly reduce the risk of developing gestational diabetes in non-White European populations. The study analyzed data from various ethnic groups and found no significant association between dietary habits and the incidence of gestational diabetes.
A study published in Med found that the human microbiome's variation explains different patient responses to statins. The researchers discovered a Bacteroides enriched microbiome with lower diversity was associated with stronger LDL-lowering effects but greater disruption of blood glucose levels.
A new study analyzed 34 previous studies on the impact of diet on gestational diabetes, finding a lack of robust data for non-white European women. The findings stress the need for inclusive research methods to accurately understand the relationship between diet and gestational diabetes across all ethnicities.
A new study suggests that screening these groups at lower BMI and younger ages could reduce undiagnosed diabetes rates and improve health equity. The findings recommend tailored approaches to address the increased risk of diabetes among Asian, Hispanic, and Black Americans.
A Washington State University study found that young adults at risk of food insecurity had a higher incidence of diabetes 10 years later. The study analyzed data from nearly 4,000 people and found that those who experienced food insecurity risk were more likely to develop diabetes in middle adulthood.
A new wearable device can simultaneously monitor glucose, alcohol, and lactate levels, providing users with a comprehensive picture of their health. This technology has the potential to improve disease management for individuals with diabetes and other conditions, as well as enhance overall wellness through real-time tracking.
A new study suggests that tailoring diabetes screening for Black, Hispanic, and Asian Americans based on lower BMI thresholds and younger ages can significantly reduce disparities in diabetes diagnosis rates. This approach may improve health equity by identifying cases earlier and reducing mortality rates associated with diabetes.
A study of 72,000 pediatric encounters found that non-Hispanic Black children were more likely to be readmitted within a year due to diabetic ketoacidosis. Healthcare disparities persist among racial and ethnic groups in pediatric care, emphasizing the need for targeted interventions.
A study found that higher levels of active brown adipose tissue are associated with early metabolic dysfunction and pre-cooling glucose, insulin, thyroid stimulating hormone, and triglyceride levels. Activated brown fat was recruited to counteract 'pre-prediabetic' states, potentially serving as a first-line protective mechanism.
A $66,000 NIH grant will support Karry Weston's two-year study on the lack of breastfeeding in rural Missouri. The goal is to identify cultural factors influencing mothers' decisions, with a focus on improving maternal care in rural communities.
The new COBRE grant will help WVU recruit researchers and clinician-scientists to develop innovative solutions for preventing and treating incurable vision problems. The project aims to reduce visual disparities in West Virginia by understanding the complex combination of factors that contribute to these problems.
A phase 2 randomized controlled clinical trial found that intranasal insulin increased walking speed, cerebral blood flow, and improved decision making and verbal memory. The treatment also showed promise for preventing or slowing the progression of Alzheimer's disease-related dementias in older adults.
A study led by Richard Isaacson found that individualized, multi-domain interventions improved cognition and reduced Alzheimer's risk in both men and women. Women demonstrated greater improvements in certain risk scores and biomarkers compared to men.
The Endocrine Society's scientific statement highlights the potential of extracellular vesicles in diagnosing and monitoring endocrine-related conditions, including cancer. These tiny vesicles may also serve as biomarkers for high blood pressure and have therapeutic roles.
A large cohort study of almost 125,000 patients found that diabetic foot ulcer outcomes are associated with race, ethnicity, and rurality. Higher rates were observed among rural and Black patients, highlighting the need for targeted interventions to address health disparities.
A team from UNIGE demonstrates that stem cells giving rise to beta cells cease to exist after birth, and defines the 'identity card' of other hormone-producing cells. This discovery has significant implications for developing cell-based therapies to treat diabetes.
A study of 309 people with long COVID found that fatigue, shortness of breath, and loss of sense of smell were the most persistent symptoms. The research also revealed that factors such as history of hospitalization, diabetes, and body mass index increased the risk of developing Long COVID.