Articles tagged with Fungal Infections
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A novel study has found that higher biodiversity reduces infectious disease severity in a Tibetan alpine meadow, supporting the dilution hypothesis. Artificial fertiliser weakens this effect, increasing disease load.
Researchers discovered Asian bat species have lower levels of infection and fungal loads compared to North American bats, suggesting host resistance as a possible explanation. This finding provides hope that some declining North American bat species could evolve resistance to the devastating disease.
A team from the University of Sheffield has discovered a white blood cell in birds that can completely block the growth of Cryptococcus neoformans, a fungus that causes fatal infections in humans. The researchers found that this macrophage cell is able to destroy the fungus when it tries to invade the bird's body.
The US Fish and Wildlife Service has imposed a ban on importing 201 species of salamanders to prevent the spread of deadly fungal disease Bsal. Researchers will discuss lessons learned from controlling another closely related fungus, Bd, which has decimated frog populations worldwide.
A new clinical imaging method has been developed to tackle one of the main killers of patients with weakened immune systems. The method uses a combination of PET and MRI imaging to identify invasive pulmonary aspergillosis, allowing for faster and more accurate diagnosis.
A new study suggests that climate change may reduce the range of the deadly chytrid fungus in Africa's Albertine Rift, potentially saving some amphibian populations. Microscopic examination revealed that most infected frogs appeared to be in good health, indicating regional resistance to the disease.
The European Respiratory Society and ESCMID have published the world's first clinical guidelines for chronic fungal lung infections, describing key features of the disease and providing comprehensive treatment recommendations. Chronic pulmonary aspergillosis affects an estimated 240,000 people in Europe and 3 million worldwide.
A study published by University of Delaware plant scientists has identified a stress hormone that appears to increase the virulence of the rice blast fungus. The research may lead to new control methods for the devastating disease.
Candidiasis is a life-threatening fungal infection requiring early treatment. New guidelines update recommendations for its diagnosis and treatment, highlighting the importance of consulting an infectious diseases (ID) specialist to ensure a good outcome.
A study reveals how CARD9 specifically protects the mammalian central nervous system (CNS) from fungal infections. Researchers found that mice and humans lacking functional CARD9 cannot recruit neutrophils to control Candida infection in the CNS, highlighting the critical role of CARD9 in promoting antifungal immunity.
Researchers at the University of Warwick have discovered that plants can predict when they'll be infected with a fungal pathogen and increase their resistance levels accordingly. The key finding is a single protein called JAZ6, which connects the plant clock to its immune system.
A US expert is urging a unified global response to the growing threat of zombie infections. Emerging outbreaks have been identified worldwide, with a range of potential causes including viruses and fungi.
Researchers have developed a new diagnostic method for a deadly fungal lung infection in leukemia patients, offering improved early detection and treatment options. The breakthrough uses distinct test results to identify the infectious mold, potentially refining diagnostics and improving survival rates.
Researchers successfully eliminated a lethal chytrid fungus in a wild amphibian population using antifungal treatment and environmental disinfection. The breakthrough study, published in Biology Letters, marks the first time a fatal fungal infection has been eradicated from a wild population.
A new study suggests that coconut oil can effectively control the overgrowth of a fungal pathogen called Candida albicans in mice. The research found that a coconut oil-rich diet reduced C. albicans in the gut by more than 90% compared to other dietary fats.
Researchers have identified Ophidiomyces ophiodiicola as the definitive cause of snake fungal disease (SFD) in eastern US snakes. The fungus causes skin lesions and can lead to mortality rates of up to 100% in some species, threatening extinction.
A new study found that Mycoplasma genitalium, a previously unknown sexually transmitted infection, affects up to 1% of the UK population aged 16-44. The infection was more prevalent among those with multiple sexual partners and in areas of higher deprivation.
A team of researchers has discovered the fungus that causes white-nose syndrome in caves where bats hibernate in northeast China. The finding greatly expands the known distribution of the fungus, which has decimated bat populations in North America since its appearance in upstate New York in 2006.
The study found that fungi change the nutritional and medicinal chemistry of milkweed leaves, affecting monarch caterpillars' susceptibility to parasitic infections. The dosage and nutrient phosphorous levels also play crucial roles in determining the outcome.
Researchers are exploring plasma-based treatments for fungal infections, as well as using plasmas to extend the shelf life of seafood. Additionally, advancements in plasma propulsion technology are being made for small spacecraft, offering potential solutions for satellite thrusters.
Researchers found that hibernating bats infected with the white nose fungus exhibited a partial immune response, including acute inflammation and wound healing. However, the influx of white blood cells into infected tissue was missing, which may be related to the unique characteristics of the Pd pathogen.
Researchers at UCSC are conducting field trials of two strategies to protect bats from white-nose syndrome, a deadly fungal disease that has devastated bat populations in eastern North America. The team aims to understand how some populations are surviving and develop effective treatments to improve their chances of survival.
The OPATHY network aims to create innovative diagnostic tools for yeast diseases by leveraging high-throughput technologies like genomics and transcriptomics. The project will provide multidisciplinary training for PhD students to develop original scientific and clinical strategies for treating yeast infections.
A biofilm with antimicrobial and anti-inflammatory properties has been developed to prevent or control post-operative infections on medical devices. The film reduces inflammation and prevents bacterial and fungal infections, offering a promising alternative to antibiotics.
Researchers discovered that Candida albicans, a deadly fungus, uses copper to fuel an enzyme designed to neutralize free radical attacks, but can switch to manganese when copper levels drop. This clever adaptation allows the fungus to survive in tissues like the kidney.
Scientists have identified 18 proteins crucial to the transformation of fungal spores into disease-causing yeast, offering hope for preventative treatments. By blocking these proteins, researchers aim to prevent the spread of meningitis and other fungal diseases.
Scientists at Australian National University discovered three previously undiscovered fungi causing the disease, which affects Southern Queensland and South Australia's wheat crops. The finding provides growers with confidence in managing the disease, crucial for a $6 billion industry.
Researchers at University of Helsinki found that black ants can change their food taste in response to fungal pathogens. By consuming a diet with high levels of free radicals, the ants show improved resistance to infections.
Researchers from the University at Buffalo have successfully disguised an antifungal protein with spermidine and a sugary compound to combat oral thrush. The new approach aims to improve treatment options for people with weakened immune systems, such as those with diabetes or undergoing chemotherapy.
A deadly fungal infection, Batrachochytrium salamandrivorans (Bsal), threatens North America's wild salamander population via the international pet trade. The fungus is highly virulent and has caused mass die-offs in Europe.
A recent fungus, Bsal, threatens American salamanders with a 96% fatality rate, highlighting the urgent need for a U.S. ban on salamander imports. The fungus's spread could imperil North American ecosystems, which rely heavily on these small, often overlooked animals.
A team of scientists has identified potential probiotics for frogs to combat the devastating chytrid fungus. The researchers found dominant bacterial species that may provide disease resistance and antifungal properties to their host. This discovery holds promise for protecting vulnerable amphibian populations worldwide.
Researchers at Rockefeller University have identified a genetic error that makes children susceptible to two unrelated diseases: aggravating fungal infections and invasive, potentially fatal bacterial disease. The mutation affects the RORC gene, which controls the production of cytokines crucial for fighting off mycobacteria.
Researchers discover fungi-specific signalling molecule controlling Candida's growth, offering hope for clinical treatments
A Duke University study shows that two biological clocks work together to help plants deal with fungal infections, while maintaining an already-packed daily schedule of activities. The researchers identified a gene called NPR1 that links the two clocks, allowing them to work together and optimize plant defenses.
Researchers find striking similarities between snake fungal disease and white-nose syndrome in bats, both persisting across habitats and infecting multiple species. The snake fungus, Ophidiomyces ophiodiicola, is highly virulent and can spread through pet trade and animal release.
Li-Jun Ma's research focuses on deciphering the mechanisms underlying fungal pathogenesis and developing novel antifungal therapies. Her work aims to address the growing threat of opportunistic fungal infections, which claim over 1.5 million lives each year.
A study published in Nature Medicine found that enhancing a specific immune response can kill infection-causing fungi, such as Candida albicans, which causes life-threatening bloodstream infections. The researchers discovered that stimulating the transcription factor HIF-1α with L-mimosine led to increased production of natural antibio...
Researchers have developed new anti-microbial compounds that specifically target fungal infections without harming human cells. These derivatives of the antifungal drug amphotericin B are highly effective in killing invasive yeast infections while showing minimal toxicity to humans.
Scientists have discovered new antifungal compounds that selectively kill pathogens without evoking drug resistance. These novel compounds were designed to act as molecular sponges for ergosterol, found exclusively on fungi surfaces, and exhibit undetectable binding to human cells.
Researchers found that a sublethal dose of imidacloprid significantly weakens termites' ability to fight off fungal diseases by knocking out key microbes in the termite gut and suppressing social hygiene habits. This combination wiped out laboratory colonies in just seven days.
The EU-funded MycoSynVac project combines gene engineering and biotechnology to design a novel veterinary vaccine chassis based on Mycoplasma pneumoniae. This chassis will be used to create specific vaccines against two highly detrimental pathogens, as well as for cell therapy and infectious lung disease treatment.
Researchers at NYU Langone Medical Center identified a crucial role for calcium signaling in controlling inflammation during chronic lung infection caused by Mycobacterium tuberculosis. Calcium channels play a key role in shutting down the immune response and preventing injurious inflammation.
Scientists have discovered a protease enzyme secreted by the fungus Pseudogymnoascus destructans that damages collagen in bats. A protease inhibitor showed a 77% reduction in collagen damage after 54 hours, offering hope for treating White Nose syndrome.
Researchers discovered a key gene that shields us from fungal and bacterial infections, and found it affects two crucial cell types involved in our immune response. STAT3 helps regulate the development and function of natural killer T and mucosal-associated invariant T cells, which play a vital role in fighting off pathogens.
A recent study published in Nature Communications has found that a little bit of sugar on the surface of fungal cells triggers the death of immune cells that would otherwise kill the fungus. This discovery could lead to a new therapeutic strategy for treating Candida albicans, one of the most common causes of bloodstream infections.
Scientists at the Max Planck Institute for Chemical Ecology identified a leaf odor, beta-cyclocitral, that specifically attracts Drosophila suzukii, a devastating fruit crop pest. This specialization allows the fly to pinpoint ripe fruits by tracking the distinct leaf odor.
Pushpa Pandiyan's research reveals that uncontrolled Th17 cells can lead to inflammation and health issues. Her study uses immunodeficient mice to model the process, which could lead to new treatments for infections like Candida albicans.
A new grant will fund research to develop a rapid diagnosis for mucormycosis, a rare fungal infection that kills more than half of its victims. The project aims to create a quick and accurate test to help physicians treat the infection promptly.
Researchers at Trinity College Dublin have discovered that naturally occurring plant-friendly fungi can prevent crop-ravishing diseases from spreading and aid plant survival in testing environmental conditions. These 'symbiotic' relationships between barley and the fungi increase plant survival by up to six times.
Researchers at the University of Toronto found that only a few strains of Candida albicans became resistant to combination therapy, and that resistance came at a cost to the fungus. The resistant strains grew poorly in stress conditions and were vulnerable to immune cells.
Researchers found that autophagy, a cellular recycling process, helps eliminate a molecule called A20 that blocks the immune response. By removing A20, autophagy allows for a quick release of emergency signals, boosting anti-fungal immunity.
Researchers have identified specialized cell walls in disease-resistant wheat varieties that could help produce stronger durum wheat for improved pasta production. The study found a new gene, WheatPME1, that can change the chemical structure of pectin, a key component of plant cell walls.
A study published in Clinical Infectious Diseases demonstrated the pivotal data for T2Candida and T2Dx, detecting Candida species with 91.1% sensitivity and 99.4% specificity in 3-5 hours without blood culture. This technology has the potential to reduce costs, length of stay, and mortality rates associated with Candida infections.
Researchers discuss the role of Malassezia yeasts as pathogens, highlighting common skin diseases such as dandruff and atopic eczema. The study also explores the potential link between Malassezia and skin cancer, as well as bloodstream infections in vulnerable populations.
A study published in Nature suggests that gut bacteria can utilize yeast carbohydrates, potentially supporting the development of new treatments for yeast infections and autoimmune diseases. The research identified a specific bacterium, Bacteroides thetaiotaomicron, with the ability to degrade complex carbohydrates in yeast cell walls.
Researchers at LA BioMed have developed a novel vaccine, NDV-3, that can protect against methicillin-resistant Staphylococcus aureus (MRSA) skin infections. The vaccine enhances molecular and cellular immune defenses of the skin in response to MRSA and other S. aureus bacteria.
A new study found that the fungus responsible for white-nose syndrome, which causes bat populations to crash, can infect nearly every bat in a colony during hibernation. Bats that survive the winter can clear the infection after they become active again, but this leads to high mortality rates at the end of winter.
Intra-abdominal infections caused by Candida albicans and Staphylococcus aureus result in high mortality rates due to synergistic inflammatory responses. Researchers hope to identify targeted treatments to decrease severity and improve survival through their study.
The FITOVID project aims to reduce fungal disease treatment in vineyards by applying less product and using new technologies for early detection. Researchers test alternative strategies, including 'zero waste' products, to boost sustainable management of pests and diseases.