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Researchers find effective combination of therapies for managing mitochondrial disease

A study by Children's Hospital of Philadelphia researchers has identified a combination therapy that provides measurable benefits to patients with mitochondrial respiratory chain disorders. The treatment, which includes glucose, nicotinic acid, and N-acetylcysteine, showed improved lifespan, mitochondrial membrane potential, and preven...

SourceChildren's Hospital of Philadelphia·JournalHuman Molecular Genetics
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Researchers propose that humidity from masks may lessen severity of COVID-19

A NIH study found that face masks increase humidity in inhaled air, which can benefit the immune system and combat respiratory diseases like COVID-19. The humidifying effects of masks vary depending on temperature and mask type, with thick cotton masks leading to the most increased level of humidity.

SourceNIH/National Institute of Diabetes and Digestive and Kidney Diseases·JournalBiophysical Journal

Can current smartphone technology tell you when a pandemic might come calling?

Researchers found that smartphone PPG technology can accurately measure blood-oxygen levels and heart rate, comparable to FDA-approved hospital instruments. This technology could enhance remote monitoring of patients with chronic cardiopulmonary disease and initial treatment for respiratory viral pandemics.

SourceUniversity of California - San Diego

New taxonomy of non-skeletal rare disorders with impact on bone

A novel taxonomic classification of rare congenital diseases with an impact on bone physiology has been established. The classification system groups disorders according to systemic disease, genetic defect, pathophysiology of bone phenotype, and therapy, providing a framework for diagnosis and treatment.

SourceInternational Osteoporosis Foundation·JournalOrphanet Journal of Rare Diseases
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Mortality rate higher for US rural residents

A recent study by Syracuse University professor Shannon Monnat found that mortality rates are higher for U.S. working-age residents living in rural areas compared to metro areas. The gap is widening, driven by increased mortality from metabolic and respiratory diseases, suicide, alcohol-related disorders, and mental/behavioral disorders.

SourceSyracuse University·JournalPopulation Research and Policy Review

The good cough and the bad cough

Researchers have identified separate brain pathways for good and bad coughs, potentially leading to new treatments for chronic cough disorders. The study used functional brain imaging to assess cough reflex sensitivity and identified two distinct neural circuits involved in coughing.

SourceThe Physiological Society·JournalThe Journal of Physiology

Researchers use precision medicine to reverse severe lymphatic disorder

A young woman with kaposiform lymphangiomatosis was treated with a MEK inhibitor, resulting in complete resolution of symptoms and remodeling of her lymphatic system within months. The treatment showed promise for other patients with lymphatic disorders.

SourceChildren's Hospital of Philadelphia·JournalEMBO Molecular Medicine
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

'Social smokers' face disproportionate risk of death from lung disease and lung cancer

A new study has found that social smokers are more than twice as likely to die of lung disease and eight times as likely to die of lung cancer compared to non-smokers. Researchers say cutting down on smoking is not a substitute for quitting, highlighting the risks of social smoking regardless of the number of cigarettes smoked.

SourceEuropean Respiratory Society

Emergency visits for thunderstorm-related respiratory illnesses

Researchers analyzed atmospheric and lightning data to study the relationship between thunderstorms and increased emergency department visits for respiratory illnesses among older adults. The study found that vulnerable groups may be susceptible to atmospheric changes caused by thunderstorms, leading to higher emergency visit rates.

SourceJAMA Network·JournalJAMA Internal Medicine

Pulmonary fibrosis treatment shows proof of principle

A pre-clinical study led by Cincinnati Children's Hospital demonstrates that barasertib reverses fibroblast activation, stopping dangerous scar tissue build-up in lungs of IPF patients. The drug targets AURKB activity, slowing disease progress and improving lung function.

SourceCincinnati Children's Hospital Medical Center·JournalEMBO Molecular Medicine
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Drug-induced interstitial lung disease in breast cancer patients

The article discusses drug-induced interstitial lung diseases caused by breast cancer treatments, which can be fatal. Multi-disciplinary integration of clinical practice and pharmacology may reduce the incidence of these diseases.

SourceCompuscript Ltd·JournalBIO Integration

Human lungs rejected for transplant recovered using novel technique

A multidisciplinary team has developed a new technique to recover human lungs declined for transplant through cross-circulation between the human lung and a xenogeneic host. This breakthrough increases organ availability, saving lives of those waiting on the transplant list.

SourceVanderbilt University Medical Center·JournalNature Medicine

World-first technology breathes new life into cystic fibrosis detection and treatment

Researchers have developed a radical non-invasive X-ray technology that can pinpoint localised areas of deficiency in lungs, improving diagnoses and treatments for cystic fibrosis. The technology, called X-ray velocimetry, measures airflow through the lungs during breathing cycles, enabling better assessment of lung function.

SourceMonash University·JournalScientific Reports

Yale, Baylor study reveals new cell types in lethal lung disease

A Yale, Baylor study reveals new cell types in lungs affected by Idiopathic Pulmonary Fibrosis (IPF), revealing how cells change in response to the disease. The findings deepen understanding of IPF and could improve treatment of it and other fibrotic lung diseases.

SourceYale University·JournalScience Advances
Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

New clues to lung-scarring disease may aid treatment

Scientists have discovered previously unreported genetic and cellular changes in the lungs of people with pulmonary fibrosis, a devastating lung-scarring disease. The findings provide remarkable insights into the fundamental mechanisms driving disease pathology in PF and may aid the search for new ways to treat or prevent the condition.

SourceVanderbilt University Medical Center·JournalScience Advances

Rheumatoid arthritis patients under treatment with methotrexate

Two studies found that methotrexate treatment does not increase the risk of chronic interstitial lung disease in RA patients, but may even delay its development. This is significant as ILD is a common complication of RA and can be life-threatening.

SourceEuropean Alliance of Associations for Rheumatology (EULAR)

COVID-19 threatens the entire nervous system

A new review reveals COVID-19 poses a global threat to the nervous system, causing neurological manifestations in about half of hospitalized patients. These symptoms include headaches, seizures, and muscle pain, and may appear before fever or cough.

SourceNorthwestern University·JournalAnnals of Neurology
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Heat now more lethal than cold for people with respiratory diseases in Spain

A new study by ISGlobal found that heat is now more lethal than cold for people with respiratory diseases in Spain, particularly women and older adults. The study analyzed data on over 1.3 million deaths between 1980 and 2016 and found a significant decline in temperature-attributable mortality during the colder months.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalNature Communications

Join ACC, global partners for dedicated week of action on NCDs

The American College of Cardiology and global partners will host a Week of Action from May 18 to 24 to raise awareness about non-communicable diseases. The event celebrates the launch of the ACC's NCD Academy, which provides free mobile app-based training for primary care providers.

SourceAmerican College of Cardiology

A gene defect associated with a severe canine lung disease identified

A genetic disorder affecting Airedale Terriers has been discovered and found to be associated with a surfactant deficiency in their lungs. The study identifies the LAMP3 gene as a candidate gene for this disease and suggests a potential link to human newborn respiratory issues.

SourceUniversity of Helsinki·JournalPLOS Genetics
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Scientists discover three genes associated with fatal lung disease

Researchers have identified three genes linked to idiopathic pulmonary fibrosis (IPF), a devastating lung disease. The discovery provides potential targets for new drugs and may lead to improved treatments.

SourceNational Institute for Health Research·JournalAmerican Journal of Respiratory and Critical Care Medicine

Yale study provides insights into how fibrosis progresses in the human lung

Researchers identified gene expression changes specific to early, progressive and end-stage fibrosis, as well as distinct molecular regulators for each stage. The study provides the first computational model of disease progression in IPF lung, accompanied by an interactive website.

SourceYale University·JournalJCI Insight
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Researchers identify new therapeutic target for pulmonary fibrosis

Researchers have identified a genetic mutation in the SFTPA1 gene that causes idiopathic pulmonary fibrosis (IPF), a progressive lung disease characterized by scar tissue buildup. Inhibiting necroptosis, a cell death pathway, could be a new therapeutic approach to treating IPF.

SourceRockefeller University Press·JournalJournal of Experimental Medicine

Natural 'breakdown' of chemicals may guard against lung damage in 9/11 first responders

A new study suggests that metabolites produced by the body's breakdown of toxins may protect against obstructive airway disease in 9/11 first responders. Researchers identified specific compounds, including protein-building amino acids and omega-3 fatty acids, which are found in diets rich in fish and olive oil.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalScientific Reports

Research offers new insight into bacterial infections found in the noses of healthy cattle

Researchers used a 'One Health' approach to study three bacterial species in the noses of young cattle, finding patterns that differ remarkably between the bacteria. The findings could help prevent and control respiratory diseases, particularly when infection becomes established in the lower respiratory tract within the lungs.

SourceUniversity of Bristol·JournalScientific Reports
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Low-income, black neighborhoods still hit hard by air pollution

Research by Ohio State University found that low-income and African-American communities continue to face disproportionate levels of air pollution, exacerbating existing health disparities. The study's findings suggest that efforts to control pollution are not effectively addressing these inequities.

SourceOhio State University

Shaky scaffold changes lung infrastructure

Lung scarring can lead to pulmonary fibrosis and life-threatening complications. Researchers found increased MMP activity in lung tissue affected by Hermansky-Pudlak syndrome, suggesting a new link for diagnosis and treatment.

SourceThomas Jefferson University·JournalOrphanet Journal of Rare Diseases

What is driving the spike in black lung disease among coal miners?

Researchers studying a $750,000 grant at the University of Illinois Chicago aim to understand how various mining dusts contribute to lung disease. They plan to collect dust samples and expose mice to different combinations to determine the most damaging mixtures.

SourceUniversity of Illinois Chicago
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

A case of the chimp sniffles or major outbreak? Syndromic surveillance may hold the key

Researchers developed a syndromic surveillance system to detect respiratory disease outbreaks in wild chimpanzees. The system identified 14 outbreaks from 2005 to 2012, including eight previously unrecorded cases, allowing for early interventions and potential disease transmission understanding worldwide.

SourceMorris Animal Foundation·JournalEcoHealth

Specific identification of chronic lung disease in premature babies

A new magnetic resonance imaging (MRI) protocol has been developed to identify premature babies with chronic lung disease, allowing for earlier diagnosis and personalized treatment. The study, published in Thorax, reveals increased T2 and decreased T1 relaxation times in MRI data, indicating the presence of Bronchopulmonary Dysplasia.

SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))·JournalThorax

Damaged lungs regenerated in study

Researchers at Vanderbilt University Medical Center developed a cross-circulation technique to rehabilitate damaged lungs, extending the assessment time from six hours to 36 hours. The regenerated lungs meet transplantation criteria, potentially increasing organ availability.

SourceVanderbilt University Medical Center·JournalNature Communications
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Bacterial contamination in household and office building tap water

A new study found sporadic presence of Legionella pneumophila and Mycobacterium avium in tap water across the US. Microbial persistence was more common in office buildings than residences, with older homes being more prone to L. pneumophila contamination.

SourceWiley·JournalJournal of Applied Microbiology

Breath of fresh air in vasculitis research

Researchers have identified an association between a MUC5B gene variant and systemic vasculitis, a lung disease prevalent in the Japanese population. The study found that patients with antineutrophil cytoplasmic antibody-associated vasculitis are more likely to have ILD if they carry this specific genetic variation.

SourceUniversity of Tsukuba·JournalAnnals of the Rheumatic Diseases

Using precision medicine, researchers discover cause and treatment for specific lung disease

A novel treatment targeting solitary B cells improved lung disease in CVID patients, offering a safer alternative to broad immunosuppressive therapies. Researchers identified elevated IgM levels as a marker of lung disease progression, allowing for precise timing of treatment and potential future therapeutic targets.

SourceBoston University School of Medicine·JournalJCI Insight
Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

Cell atlas of the aging lung

A study published in Nature Communications reveals that genes in lung cells lose synchronized behavior with age, leading to changes in gene activity and metabolic pathways. The researchers also found alterations in the extracellular matrix surrounding lung cells, affecting protein composition.

SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))·JournalNature Communications

ATS publishes new clinical guideline on home oxygen for children

The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy in children with chronic hypoxemia. The guideline makes specific recommendations for treating various respiratory and pulmonary conditions, such as cystic fibrosis, bronchopulmonary dysplasia, and interstitial lung disease.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine

How our cellular antennas are formed

Researchers from UNIGE develop in vitro system to form microtubule doublets, revealing crucial role of tubulin in preventing uncontrolled ciliary structure formation. This discovery may lead to new treatments targeting differences between human and pathogen cilia.

SourceUniversité de Genève·JournalScience
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Silicosis is on the rise, but is there a therapeutic target?

A study published in Nature Communications identifies extracellular DNA degradation as a key mechanism of lung inflammation induced by silica exposure. Treatment with DNase I may prevent silica-induced lung inflammation, suggesting a new therapeutic target for silicosis.

SourceCNRS·JournalNature Communications

Targeting scar-free wound healing

A European Research Council Consolidator grant has been awarded to Dr. Yuval Rinkevich's team at Helmholtz Munich to study the role of fibroblasts in wound healing, with a focus on determining how differences in their populations affect scarring outcomes.

SourceHelmholtz Munich (Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH))

Your showerhead slime is alive

Researchers found Mycobacterium bacteria thriving in US showerheads, particularly in areas with high rates of lung disease. The study also revealed geographic patterns and material-specific influences on bacterial growth.

SourceUniversity of Colorado at Boulder·JournalmBio
AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Body mass index associated with deaths from most causes

Research suggests a BMI of 21-25kg/m2 is associated with the lowest risk of dying from cancer and heart disease. The study found that underweight individuals were more likely to die from various causes, including cardiovascular disease, respiratory disease, and dementia.

SourceLondon School of Hygiene & Tropical Medicine·JournalThe Lancet Diabetes & Endocrinology

New genetic pathways linked to severe lung disease in preemies

Scientists have discovered new genetic pathways associated with severe lung disease in premature infants, including those related to gonadotropin releasing hormone and heart development. These findings offer promise for earlier risk detection and the development of more precise treatments for this life-threatening condition.

SourceAnn & Robert H. Lurie Children's Hospital of Chicago·JournalBMC Genetics

CU researchers find common genetic link in lung ailments

A team of CU researchers has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis. The study found that patients with RA are at risk of developing progressive pulmonary fibrosis, enabling potential interventions to prevent this condition.

SourceUniversity of Colorado Anschutz Medical Campus·JournalNew England Journal of Medicine

E-cigarette explosion and burn injuries have been underestimated by federal agencies

A new study by George Mason University found an estimated 2,035 emergency department visits from e-cigarette explosion and burn injuries between 2015-2017, underscoring the need for improved surveillance and regulation. The devices contain harmful substances like nicotine and ultrafine particles, posing serious health risks.

SourceGeorge Mason University·JournalTobacco Control
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

More than half of countries are not on track to meet global targets for chronic diseases

A new analysis published in The Lancet found that more than half of all countries are not on track to meet the UN target to reduce premature deaths from non-communicable diseases by a third by 2030. For women aged 30-70, only 9% of countries are on track, and for men, it's just 3%. The study highlights the need for policy changes to ad...

SourceThe Lancet·JournalThe Lancet

First mouse model to mimic lung disease could speed discovery of more effective treatments

Researchers have developed a mouse model that induces scarring and damage similar to human idiopathic pulmonary fibrosis, allowing for the study of new pathways and targets. The model enables the testing of drugs in more clinically relevant ways, potentially leading to more effective therapeutic options.

SourceUniversity of Pennsylvania School of Medicine·JournalJournal of Clinical Investigation

Taking a pill can effectively treat brutal lung disease

Researchers discovered that cholesterol disruption causes PAP, a condition where air sacs clog with surfactant. A clinical trial to test statin therapy is planned, showing improved respiratory function in patients and laboratory models.

SourceCincinnati Children's Hospital Medical Center·JournalNature Communications
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.