Articles tagged with Blood Chemical Analysis
The Alliance QUANTUM trial is testing whether post-transplant consolidation therapy with teclistamab improves survival in patients with primary plasma cell leukemia. Plasma cell leukemia is a rare but aggressive blood cancer with poor long-term survival rates.
A study published in EBioMedicine found changes in blood samples from almost 1,000 people hospitalized for COVID-19 may pinpoint patients at risk of long-term lung disease. The study identified elevated levels of certain molecules, which could lead to the development of simple blood tests to detect ongoing lung problems.
A novel optical microneedle device developed by researchers can quantify glucose levels in ultra-trace samples with high precision, offering a potential solution for blood-sampling-free clinical testing. The device features a functional hydrogel at its tip that reversibly binds to glucose, enabling accurate analysis without consuming t...
A recent study at the University of Gothenburg discovered that two medications, cholestyramine and colesevelam, can rapidly eliminate perfluoroalkyl substances (PFAS) from the body. The findings suggest a potential therapeutic application for these medicines in reducing PFAS levels.
A study by the University of the Basque Country found 18 different PFAS compounds in children's plasma, with detection rates ranging from 70% to 97%. The research warns that current regulations may not be effective in regulating emerging PFAS compounds and calls for further studies on their toxicity.
A landmark clinical trial found that Transcendental Meditation significantly reduced diabetes risk factors and supported weight loss in older Black women at high risk for heart disease. Meditation improved blood sugar control, insulin resistance, cholesterol, and weight.
Scientists have developed a low-cost and easy-to-use diagnostic tool for assessing cardiovascular disease risk using molecular blood screening. The technology enables high-throughput analysis of key lipoprotein markers in under 15 minutes, providing clinicians with a rapid and reliable diagnostic tool.
The Rice team created a low-cost, pump-free flow cytometer that uses gravity-driven slug flow to analyze cells with similar accuracy as conventional devices. The device is powered by AI and can count specific immune cells from unpurified blood samples within minutes.
A new study reveals that PFAS are found in larger volumes than before, with a significant increase in the livers of wading birds. The researchers used a new method called the Total Oxidizable Precursor (TOP) assay to detect these substances.
A new study at U-M Health shows that hospitals can focus the use of preoperative tests on high-risk patients, while safely reducing unnecessary testing in others. The result is less wasted money and resources, as well as less time wasted for patients and clinical staff.
Researchers at Binghamton University have developed a new paper-based biosensor system that uses bacterial spores to monitor glucose levels in sweat, eliminating the need for finger-stick devices. The system is shelf-stable, self-replicating, and can endure harsh environments, making it a promising alternative for diabetes management.
The Institute of Physical Chemistry of the Polish Academy of Sciences has developed a novel system for determining potassium levels in liquid food samples using fast and non-destructive techniques. The low-cost, ion-selective syringe electrodes offer excellent selectivity and linear range, making them suitable for point-of-care devices.
The study identified 105 compounds in Shenqi Fuzheng extract, with organic acids and amino acids showing higher concentrations in the bloodstream. Compounds such as Astragalosides promptly enter the bloodstream within 5 minutes after administration.
Researchers found that living in neighborhoods with low food access, contaminated drinking water, and proximity to Superfund sites increases PFAS levels in blood. The study provides evidence for addressing neighborhood-level factors in reducing racial and ethnic environmental health disparities.
Scientists use machine learning-based classifiers to differentiate lung cancer and noncancer based on urinary miRNA ensembles. The study reveals high specificity and sensitivity in detecting early-stage lung cancer, offering new hope for improved patient outcomes.
More than 70 hematology researchers from the University of Miami Miller School of Medicine will showcase their work at the 66th ASH Annual Meeting & Exposition. Researchers from Sylvester Comprehensive Cancer Center are authors or co-authors on a significant number of posters presented during the event.
A new study from the University of Texas at Arlington suggests that analyzing RNA in urine can show changes in cell types, revealing early signs of cancer and other diseases. This method could help clinicians detect problems earlier when they are more easily treated without invasive procedures.
Researchers at USC found a link between per- and polyfluoroalkyl substances (PFAS) and kidney damage, which may be tied to dysregulation of the gut microbiome. The study, published in Science of the Total Environment, suggests that changes in gut bacteria and related metabolites can explain up to 50% of decreased kidney function.
A UFZ study found that individual chemicals can have additive effects on human health when combined with other chemicals, leading to increased neurotoxicity. The research analyzed blood samples from pregnant women and found that even low concentrations of chemicals could cause adverse effects on nerve-like cells.
A study published in Environmental Advances found a significant association between four types of PFAS and poor sleep in young adults. The researchers identified genes involved in the body's natural defenses and a hormone that regulates sleep, shedding light on the underlying mechanisms of PFAS' impact on sleep.
A new study published in JAMA Network Open found that children exposed to indoor vaping absorb 84% less nicotine than those exposed to indoor smoking, while those exposed to neither absorbed 97% less. This suggests that second-hand exposure to harmful substances in e-cigarettes is likely to be much lower still.
The NTU team created a compact and flexible light-based sensing device, like a plaster, to provide highly accurate biomarker readings within minutes. The device detects glucose, lactate, and urea levels in sweat with ultra-high sensitivity and dynamic range.
A new study found that higher lifestyle scores associated with better heart health can lead to a younger biological age and lower risk of heart disease and stroke. The study used DNA methylation levels as a biomarker to estimate biological age.
Researchers at Toyohashi University of Technology developed a novel integrated immunoassay device with autonomous control functions, reducing analysis time by one-third to 30 minutes. The centrifugal microfluidic chip can perform complex fluid control without extensive user training or manual labor.
Researchers developed a bioelectronic chip that can detect vitamins C and D in body fluids, offering a low-cost and easy-to-use solution for micronutrient monitoring. The chip is disposable, flexible, and can be adapted for wearable devices, enabling personalized diets and prevention of deficiencies.
Scientists have identified a consistent signature of multiple sclerosis in the blood of patients years before they develop symptoms. The discovery, published in Nature Medicine, could lead to earlier diagnosis and treatment of the disease, affecting nearly 1 million people in the US.
A new study finds that e-cigarette users with a limited smoking history experience similar DNA changes to specific cheek cells as smokers. The researchers also found that some smoking-related epigenetic changes remain more stable after giving up smoking, suggesting that e-cigarettes may not be completely safe.
A new biomarker, N-methylpyridinium, has been validated for coffee consumption and is considered a reliable qualitative biomarker. The substance is specific to roasted Arabica and Robusta coffee and can be easily detected in various body fluids after coffee consumption.
Researchers at the University of Waterloo have developed a rapid blood testing method that can detect fentanyl and other opioids in under three minutes, making it twice as quick as traditional approaches. This new technique has the potential to save lives by quickly identifying overdoses.
Researchers have developed a device that detects glucose and adenosine monophosphate biomarkers in saliva with high sensitivity, enabling easy at-home health monitoring. The electrochemical aptamer-based biosensor is simple, accurate, and stable, making it suitable for use without laboratory equipment.
A new blood test has been developed to measure the levels of critical omega-3 fatty acids in the bloodstream, providing a convenient way to assess cardiovascular and cognitive health. The Omega-3 Index (O3I) is derived from two key fatty acids, EPA and DHA, which can be obtained only from certain dietary sources.
A phase 2 clinical trial found that serial blood tests can identify patients who benefit from additional immunotherapies, suggesting a potential early marker of treatment response. The study also showed that ctDNA analyses correlated with tumor size and survival, making it a promising strategy for guiding therapy.
Researchers analyze ancient documents to shed light on the health of Vlad III, the legendary inspiration behind Count Dracula. The study reveals potential signs of respiratory problems and a condition that could have caused him to cry blood.
A new study suggests that replacing traditional protein sources with mealworms in high-fat diets can slow weight gain and improve immune response, inflammation, energy metabolism, and cholesterol profiles. Mealworm protein also beneficially alters the ratio of good to bad cholesterol.
A German research team has successfully developed a novel NMR technique to quantify acute-phase proteins in human serum, which can serve as markers for inflammatory diseases. The study found significant changes in specific acute-phase proteins in patients with COVID-19 or cardiogenic shock, and offers a diagnostic potential.
Researchers discovered bimetallic tartrate complexes with unique structures, formed by insufficient ligand, leading to improved sensor characteristics for microbiosensors. The study showcases the potential of laser-induced chemical liquid phase deposition for creating nanostructures with various applications.
A recent study by the University of Bergen found that 22% of Norwegian children aged 6-16 had PFAS levels above the safety limit set by the European Food and Safety Authority. This exposure has been linked to reduced vaccine response, lower birth weight, and certain types of cancers.
A study by Florida Atlantic University and Duke University reveals that the malaria parasite's biological clock is 'in sync' with its human host's circadian clock. The researchers discovered a 'coupling' mechanism between the parasite and its host, which could lead to new treatments for this deadly disease.
A novel fluorescence probe successfully quantifies trace components like hydrogen sulfide in whole blood, overcoming autofluorescence interference. The probe uses a borodipyrromethene-based dye that quenches the interfering light, allowing for accurate measurements.
MIT chemists develop rapid test to determine whether individuals have neutralizing antibodies against Covid-19, offering protection against future infections. The technique uses a fingerprint of sugar molecules to identify neutralizing antibodies in blood samples.
Researchers have identified a blood protein snapshot that documents changes in patients with severe liver disease caused by heavy drinking, potentially leading to a simple blood test for diagnosis and treatment monitoring.
Researchers found that female lymphoma patients who received afternoon chemotherapy had a 12.5 times reduced mortality rate and a 2.8 times decreased cancer recurrence rate compared to morning treatment. This is due to the body's natural circadian rhythm, which affects white blood cell counts and bone marrow proliferation.
A pooled data analysis of 10 randomized controlled trials involving 1040 women found that acupuncture significantly relieved pain during pregnancy, improved physical function, and quality of life. The therapy was also found to be safe, with no observable major side effects for newborns.
A new study finds that California coastal condors are at increased risk of reproductive impairment due to consuming dead marine mammals contaminated with banned chemicals like DDT and PCBs. Baja California, Mexico, presents a reduced risk compared to the California coast.
The CodeBreaK 100 trial demonstrated prolonged tumor responses and favorable safety profiles in patients treated with sotorasib. Long-term treatment was well-tolerated, with a two-year overall survival rate of 32.5%.
A study from North Carolina State University demonstrates the accuracy of a less invasive technique for monitoring wildlife health using dried blood spots. Researchers found that this method is comparable to traditional techniques, allowing for easier and less stressful data collection from wild populations.
Epidemiologists have developed a new blood test, DunedinPACE, to measure biological aging. The test uses DNA methylation marks to track changes in organ-system integrity over time, predicting future disease and mortality.
Researchers at Skoltech have created an optoacoustic endoscopic probe that can analyze atherosclerotic plaques by forcing molecules to sound their presence. The device uses laser light to make biomarkers oscillate, producing ultrasound signals that can be detected by a sensitive microphone.
A new WHO autoantibody reference reagent has been developed to align autoantibody analyses, improving diagnosis and treatment for patients with Systemic Lupus Erythematosus (SLE) worldwide. The reference reagent was evaluated in an international study and showed significant improvements in differences between different anti-dsDNA assays.
Research in Costa Rica found that pesticide use in banana plantations is contaminating protected conservation areas, affecting spectacled caiman species. The study highlights the need for improved regulatory infrastructure to mitigate pesticide damage to aquatic ecosystems.
Researchers developed a highly sensitive method to determine titanium levels in human blood, establishing a baseline for natural levels and measuring levels in patients with surgical implants. The study found significantly higher titanium concentrations in patients with implants, shedding light on the potential harmful biological effects.
Researchers at University of Alberta have identified over 4,200 blood chemicals that doctors can use to diagnose and treat health problems. The new database provides a comprehensive reference point for monitoring patient health and detecting early signs of medical issues.
David Wetzel's new technique uses infrared microspectroscopy to analyze small specimens without grinding or staining, revealing localized chemical content and spatial resolution. The technology has increasing applications in biological and other research, including rare blood disorders and hit-and-run cases.