Articles tagged with Cardiology
The EMPEROR-Preserved risk model demonstrated good performance in the FINEARTS-HF trial, showing that baseline risk does not modify the relative treatment effect of finerenone. Finerenone has been shown to have a significant benefit for heart failure patients.
A post hoc analysis found that tirzepatide was associated with a lower incidence of a broad composite cardiovascular and kidney endpoint. The study compared tirzepatide with dulaglutide in patients with diabetes and established cardiovascular disease.
The MOMENTUM study found that 27% of patients with resistant hypertension have hypercortisolism, a condition characterized by elevated cortisol levels. This finding suggests that hypercortisolism may be an underlying cause of resistant hypertension, which impacts nearly 10 million patients in the US.
A post hoc analysis of the Finerenone Trial reveals that sudden death in heart failure was often preceded by modest worsening of symptoms and declining quality of life. The study suggests limited specificity for sudden death among other modes of death, implying a complex trajectory before modes of death.
The new guideline focuses on lowering elevated LDL cholesterol levels and emphasizes the importance of earlier screenings, especially for those with a family history of heart disease. It also encourages more personalized risk estimations to support shared decision-making between clinicians and patients.
A £43M EU-funded initiative, COMPASS, aims to detect heart-related risks in cancer patients and survivors using innovative medical and digital technologies. The project will develop AI-powered clinical pathways to enhance cardiotoxicity detection, safer treatment, and better long-term cardiovascular outcomes.
Research suggests living in areas with high levels of transportation noise is associated with a significantly higher risk of major adverse cardiac events. Loud road, aviation, and rail noises were linked to increased risks of heart attack, stroke, or coronary revascularization. Different types of noise may come with unique health risks...
Nine medical societies endorse 'ALARA+' safety framework to minimize radiation exposure and orthopedic strain in fluoroscopy labs, aiming to ensure safer environments, equipment, and care. The new standard aims to reduce occupational harms affecting healthcare staff, including chronic pain and spinal conditions.
A study found that high screen time and low physical activity are strongly linked with cardiovascular risk among young adults. Screen time was independently associated with markers of cardiovascular risk, even after accounting for differences in daily physical activity.
A study analyzing monthly temperatures and cardiovascular deaths found that cold weather accounted for about 6.3% of all cardiovascular deaths, resulting in 800,000 excess deaths over two decades. The research highlights the need for communities to prepare for climate change's impact on extreme cold.
A study found that Medicare beneficiaries with heart disease reported less cost-related medication non-adherence after new provisions limited out-of-pocket drug costs. This decrease was particularly notable among low-income seniors, who saw a significant reduction in skipped or delayed doses.
A new 4D digital heart model has been shown to improve patient outcomes in cardiac resynchronization therapy (CRT) for heart failure. The model, developed at the University of Calgary, enables personalized pacemaker placement, leading to a 10.8% increase in heart function compared to standard care.
Children with metabolically healthy obesity at treatment initiation have an increased risk of type 2 diabetes, hypertension, and dyslipidemia. Reduction in BMI z score is associated with reduced cardiometabolic risk, suggesting treatment should be recommended for these children as well.
A Korea University study reveals that liver metabolic disease is a key risk factor for heart failure in older adults with atrial fibrillation, with MASLD having the lowest risk and ALD carrying the highest risk. The study highlights the importance of liver health in cardiovascular disease management.
Researchers found that a novel blood biomarker, neurofilament light chain, is associated with long-term cognitive function in survivors of out-of-hospital cardiac arrest. In contrast, neuron-specific enolase levels were not linked to cognitive impairment. Early measurement of neurofilament light chain may help identify patients at high...
A study by European Society of Cardiology found that AI-based ECG interpretation outperformed standard pathways in detecting occlusive myocardial infarction (MI) without ST elevation. The AI tool correctly identified obstructive MI in 84% of cases, with high sensitivity and specificity rates.
The 2020 facility revision criteria for rotational atherectomy did not increase adverse events among patients treated for coronary artery disease. The expansion of RA eligibility to low-volume, non-training hospitals improved patient care and reduced geographical disparities.
Researchers developed a new multiview DNN structure to capture complex 3D anatomy and physiology from multiple imaging views, improving diagnostic accuracy for cardiovascular conditions. The approach demonstrated better performance than single-view DNNs and provided a viable alternative for other medical imaging modalities.
Maintaining a healthy lifestyle, including a high-quality diet, moderate exercise, and low alcohol consumption, was associated with lower cardiometabolic disease risk. The study found that adhering to these healthy behaviors reduced the risk of major cardiometabolic diseases independent of medication use.
Consuming ultra-processed foods daily is associated with a higher risk of adverse cardiac events, particularly among Black Americans. The study found that each additional serving increases the risk by over 5%, with Black Americans seeing an amplified risk compared to other racial groups.
The RESIL-Card tool helps hospital cardiovascular professionals and stakeholders assess and strengthen care pathways, ensuring continuity of care during crises. The tool offers a structured self-assessment framework, identifying concrete actions to maintain care continuity and patient safety.
A new RNA therapy has been developed to enhance the heart's own ability to protect and repair itself after a heart attack. The therapy, which involves injecting particles into the arm, significantly reduced scarring and improved heart function in lab experiments, offering a potential breakthrough for heart patients.
A 16-year study found that 87% of children with single-ventricle heart disease either died or developed a major health problem over time. The study provides new direction for improving care and offers guidance for tailoring therapies to each child.
A large cohort study found that people using anticholinergic medications, commonly prescribed for urinary incontinence and anxiety, have a higher risk of developing cardiovascular disease. The cumulative use of these drugs was associated with an increased risk of heart failure and arrhythmias.
A new study by Cleveland Clinic and Dyania Health demonstrates the potential of large language models in accurately identifying patients who could benefit from clinical research. The AI system reviewed 1,476 patients and identified 46 as potential matches, resulting in a more diverse patient population.
A Mayo Clinic study found that a single dose of non-prescribed Adderall can have measurable cardiovascular effects in healthy young adults, including significant increases in blood pressure and heart rate. The study highlights the risks of unsupervised use of stimulants like Adderall.
The ORIGIN study uses advanced molecular tools to identify risk factors and early warning signals in stored blood samples from up to 13,000 service members. By analyzing these data, researchers aim to predict and prevent diseases such as cancer, heart disease, and autoimmune disorders years before symptoms appear.
Research highlights the challenges of managing an early-onset cardiovascular condition while raising younger children, including uncertainty about communicating with children, physical and emotional strain on daily life, and heightened awareness of potential genetic risks. The study emphasizes the need for developmentally appropriate c...
A team of researchers from the University of Oldenburg has discovered a unique genetic pattern, or 'fingerprint', associated with NOTCH1 gene variants that commonly cause congenital heart defects. This breakthrough enables more reliable diagnoses and targeted therapies for patients and their families.
A study published in European Heart Journal found that nearly half of hospitalised heart failure patients are readmitted within a year, with the risk of death also remaining high. Patients with severely reduced heart function face the highest risk, highlighting the need for careful follow-up and tailored care.
Researchers developed a new model to predict long-term survival after heart failure in elderly Japanese patients. The Top-20 XGBoost model incorporates physical function metrics, rivaling the importance of traditional cardiovascular risk factors, and provides a more accurate estimation of mortality risk.
A group of nerve cells in the brainstem has been identified as a stabilizing system for blood pressure, preventing fluctuations between daily activities. The study suggests that loss or dysfunction of these cells can lead to unstable blood pressure and is associated with conditions such as multiple system atrophy.
A Mount Sinai-led study developed an AI tool that analyzes ECGs to identify patients at risk for harmful heart changes, potentially reducing the need for expensive and time-consuming cardiac MRI scans. The tool could make lifelong heart monitoring more accessible and efficient for people born with congenital heart disease.
The American College of Cardiology has recognized Plicy Perez-Kersey, MD, as the first recipient of the Thad and Gerry Waites Rural Cardiovascular Research Fellowship Award. The fellowship provides up to $70,000 in research funding to support rural cardiovascular care and community engagement.
A study by University of Virginia Health System researchers found that Medicare Advantage patients had better access to preventive care and rehabilitation after a stroke, leading to faster recovery times. In contrast, traditional Medicare patients were less likely to receive these services due to prior authorization requirements.
Researchers developed a new MRI technique that simultaneously displays heart tissue and blood flow, enabling precise planning for surgical repairs. This innovation provides high-quality flow images without radiation, making it essential for repeated imaging in children.
A new study found that aligning overnight fasting with the body's natural sleep-wake rhythm improved cardiovascular and metabolic health. Participants who extended their fast by two hours and dimmed lights three hours before bedtime showed significant improvements in blood pressure, heart rate, and blood-sugar control.
The Congressional Peripheral Artery Disease (PAD) Caucus will focus on legislative priorities including timely diagnosis, evidence-based treatment, and innovative therapies. The event brings together lawmakers, medical experts, and patient advocates to address the critical gap in PAD management.
The study found that a novel subset of white blood cells becomes infected in the lung and produces type 1 interferon, which triggers cardiac damage. A modified mRNA treatment was shown to mitigate cardiac damage while preserving the immune system's protective response. The research offers great promise for developing new therapies to p...
A new study from CU Anschutz researchers found that regular physical activity can significantly lower post-ablation atrial fibrillation recurrence risk. Adults who engaged in moderate exercise for 30 minutes three times a week had markedly lower rates of AF recurrence compared to those who were less active.
The Accelerating Kids’ Access to Care Act removes administrative barriers, enabling children with complex or congenital medical conditions to access out-of-state specialty care. This legislation ensures timely, coordinated care for children in need of lifesaving treatment from highly specialized pediatric interventional cardiologists.
A new AI-enabled digital stethoscope has been shown to significantly improve the detection of moderate to severe valvular heart disease in routine clinical examinations. The tool achieved a sensitivity rate of 92.3% compared to traditional stethoscopes, enabling earlier diagnosis and potentially reducing complications. By providing an ...
A new study found semaglutide to be an effective treatment for preventing secondary cardiovascular disease in US adults. The medication meets conventional thresholds when used alone, but its cost-effectiveness is improved with combination therapy.
The Society for Cardiovascular Angiography & Interventions has released an expert opinion on the use of wire-free angiography-derived physiology (ADP) in coronary artery disease assessment. ADP uses computational modeling or AI to analyze standard coronary angiographic images, offering a potentially more efficient and effective approac...
A recent study found that respiratory syncytial virus (RSV) hospitalizations are associated with a higher risk of cardiorespiratory events, with some conditions experiencing elevated risks up to 180 days after admission. The findings highlight the importance of increasing RSV immunization in adults to mitigate this risk.
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
A new AI tool has been developed to predict the chances of death, major bleeding, or another cardiac event in cancer patients who have had a heart attack. The ONCO-ACS score combines cancer-related factors with standard clinical data to provide individualized treatment recommendations.
A new study has identified optimized immunosuppressive strategies that allow transplanted iPSC-CMs to survive without immune rejection in non-human primates. The researchers found a triple-drug regimen consisting of methylprednisolone, calcineurin inhibitors, and mycophenolate mofetil reliably prevents acute immune rejection.
A nationwide survey found that 61% of Americans are unaware of non-statin medications to lower cholesterol, while 73% have never heard of lipoprotein(a) or coronary artery calcium score testing. Non-statin options include Ezetimibe, PCSK9 Inhibitors, and Bempedoic Acid, which can help patients at risk for heart disease.
Smartwatches with PPG and ECG functionality improve atrial fibrillation detection, detecting it four times more often than standard care. Researchers detected heart arrhythmia in 21 patients using smartwatches compared to five in those receiving standard care after six months of monitoring.
The joint statement highlights the significant impact of environmental stressors on cardiovascular disease, with an estimated 4-6 million deaths per year. It calls for urgent action to adopt stricter air quality and noise standards, phase out fossil fuels, and regulate toxic chemicals.
Researchers at the University of Houston have discovered that loss-of-function in epicardial proteins leads to left ventricular noncompaction, or spongy heart, causing pediatric-onset heart failure. A new therapeutic approach may prevent babies from being born with this life-threatening disease.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
Fine particulate matter and ozone exposure independently associated with poorer cardiac health outcomes in breast cancer patients treated with cardiotoxic therapy. Environmental exposure modifications are crucial to mitigate cardiovascular disease risk.
The Cities@Heart project aims to improve cardiovascular health in cities through integrated whole-city approaches, targeting obesity, high blood pressure, and diabetes. The consortium will design, pilot, and evaluate city-level strategies to reduce the burden of cardiovascular disease on urban environments and improve quality-of-life.
A new study reveals a significant association between police-related stress and physical markers of cardiovascular health risk in Black women. Women who expressed concern for their children's potential interactions with police had thicker carotid artery walls, indicating increased cardiovascular risk.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
A cohort study found that very high lipoprotein(a) levels increased the 30-year risk of cardiovascular disease among healthy women. Screening for elevated lipoprotein(a) may be warranted in the general population.
A new study from UCLA Health found that a cardiovascular risk score can predict who will develop serious eye diseases years later. Higher cardiovascular risk scores were significantly more likely to develop conditions like age-related macular degeneration, diabetic retinopathy, and glaucoma.
In a prespecified exploratory analysis of the SELECT randomized clinical trial, semaglutide demonstrated significant reductions in hospital admissions and overall time spent in hospital. This finding suggests that semaglutide has broader health benefits for patients with obesity and established cardiovascular disease.