Research from the field of heart medicine. Covers light exposure and heart health, lifestyle and longevity, and regional cardiology care.
A new study by Cleveland Clinic and Dyania Health demonstrates the potential of large language models in accurately identifying patients who could benefit from clinical research. The AI system reviewed 1,476 patients and identified 46 as potential matches, resulting in a more diverse patient population.
The ORIGIN study uses advanced molecular tools to identify risk factors and early warning signals in stored blood samples from up to 13,000 service members. By analyzing these data, researchers aim to predict and prevent diseases such as cancer, heart disease, and autoimmune disorders years before symptoms appear.
A Mayo Clinic study found that a single dose of non-prescribed Adderall can have measurable cardiovascular effects in healthy young adults, including significant increases in blood pressure and heart rate. The study highlights the risks of unsupervised use of stimulants like Adderall.
A team of researchers from the University of Oldenburg has discovered a unique genetic pattern, or 'fingerprint', associated with NOTCH1 gene variants that commonly cause congenital heart defects. This breakthrough enables more reliable diagnoses and targeted therapies for patients and their families.
Research highlights the challenges of managing an early-onset cardiovascular condition while raising younger children, including uncertainty about communicating with children, physical and emotional strain on daily life, and heightened awareness of potential genetic risks. The study emphasizes the need for developmentally appropriate c...
A study published in European Heart Journal found that nearly half of hospitalised heart failure patients are readmitted within a year, with the risk of death also remaining high. Patients with severely reduced heart function face the highest risk, highlighting the need for careful follow-up and tailored care.
Researchers developed a new model to predict long-term survival after heart failure in elderly Japanese patients. The Top-20 XGBoost model incorporates physical function metrics, rivaling the importance of traditional cardiovascular risk factors, and provides a more accurate estimation of mortality risk.
A group of nerve cells in the brainstem has been identified as a stabilizing system for blood pressure, preventing fluctuations between daily activities. The study suggests that loss or dysfunction of these cells can lead to unstable blood pressure and is associated with conditions such as multiple system atrophy.
A study by University of Virginia Health System researchers found that Medicare Advantage patients had better access to preventive care and rehabilitation after a stroke, leading to faster recovery times. In contrast, traditional Medicare patients were less likely to receive these services due to prior authorization requirements.
A Mount Sinai-led study developed an AI tool that analyzes ECGs to identify patients at risk for harmful heart changes, potentially reducing the need for expensive and time-consuming cardiac MRI scans. The tool could make lifelong heart monitoring more accessible and efficient for people born with congenital heart disease.
The American College of Cardiology has recognized Plicy Perez-Kersey, MD, as the first recipient of the Thad and Gerry Waites Rural Cardiovascular Research Fellowship Award. The fellowship provides up to $70,000 in research funding to support rural cardiovascular care and community engagement.
A new study found that aligning overnight fasting with the body's natural sleep-wake rhythm improved cardiovascular and metabolic health. Participants who extended their fast by two hours and dimmed lights three hours before bedtime showed significant improvements in blood pressure, heart rate, and blood-sugar control.
Researchers developed a new MRI technique that simultaneously displays heart tissue and blood flow, enabling precise planning for surgical repairs. This innovation provides high-quality flow images without radiation, making it essential for repeated imaging in children.
The Congressional Peripheral Artery Disease (PAD) Caucus will focus on legislative priorities including timely diagnosis, evidence-based treatment, and innovative therapies. The event brings together lawmakers, medical experts, and patient advocates to address the critical gap in PAD management.
The study found that a novel subset of white blood cells becomes infected in the lung and produces type 1 interferon, which triggers cardiac damage. A modified mRNA treatment was shown to mitigate cardiac damage while preserving the immune system's protective response. The research offers great promise for developing new therapies to p...
A new study from CU Anschutz researchers found that regular physical activity can significantly lower post-ablation atrial fibrillation recurrence risk. Adults who engaged in moderate exercise for 30 minutes three times a week had markedly lower rates of AF recurrence compared to those who were less active.
The Accelerating Kids’ Access to Care Act removes administrative barriers, enabling children with complex or congenital medical conditions to access out-of-state specialty care. This legislation ensures timely, coordinated care for children in need of lifesaving treatment from highly specialized pediatric interventional cardiologists.
A new AI-enabled digital stethoscope has been shown to significantly improve the detection of moderate to severe valvular heart disease in routine clinical examinations. The tool achieved a sensitivity rate of 92.3% compared to traditional stethoscopes, enabling earlier diagnosis and potentially reducing complications. By providing an ...
A new study found semaglutide to be an effective treatment for preventing secondary cardiovascular disease in US adults. The medication meets conventional thresholds when used alone, but its cost-effectiveness is improved with combination therapy.
The Society for Cardiovascular Angiography & Interventions has released an expert opinion on the use of wire-free angiography-derived physiology (ADP) in coronary artery disease assessment. ADP uses computational modeling or AI to analyze standard coronary angiographic images, offering a potentially more efficient and effective approac...
A recent study found that respiratory syncytial virus (RSV) hospitalizations are associated with a higher risk of cardiorespiratory events, with some conditions experiencing elevated risks up to 180 days after admission. The findings highlight the importance of increasing RSV immunization in adults to mitigate this risk.
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
A new AI tool has been developed to predict the chances of death, major bleeding, or another cardiac event in cancer patients who have had a heart attack. The ONCO-ACS score combines cancer-related factors with standard clinical data to provide individualized treatment recommendations.
A new study has identified optimized immunosuppressive strategies that allow transplanted iPSC-CMs to survive without immune rejection in non-human primates. The researchers found a triple-drug regimen consisting of methylprednisolone, calcineurin inhibitors, and mycophenolate mofetil reliably prevents acute immune rejection.
A nationwide survey found that 61% of Americans are unaware of non-statin medications to lower cholesterol, while 73% have never heard of lipoprotein(a) or coronary artery calcium score testing. Non-statin options include Ezetimibe, PCSK9 Inhibitors, and Bempedoic Acid, which can help patients at risk for heart disease.
Smartwatches with PPG and ECG functionality improve atrial fibrillation detection, detecting it four times more often than standard care. Researchers detected heart arrhythmia in 21 patients using smartwatches compared to five in those receiving standard care after six months of monitoring.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
The joint statement highlights the significant impact of environmental stressors on cardiovascular disease, with an estimated 4-6 million deaths per year. It calls for urgent action to adopt stricter air quality and noise standards, phase out fossil fuels, and regulate toxic chemicals.
Researchers at the University of Houston have discovered that loss-of-function in epicardial proteins leads to left ventricular noncompaction, or spongy heart, causing pediatric-onset heart failure. A new therapeutic approach may prevent babies from being born with this life-threatening disease.
Fine particulate matter and ozone exposure independently associated with poorer cardiac health outcomes in breast cancer patients treated with cardiotoxic therapy. Environmental exposure modifications are crucial to mitigate cardiovascular disease risk.
The Cities@Heart project aims to improve cardiovascular health in cities through integrated whole-city approaches, targeting obesity, high blood pressure, and diabetes. The consortium will design, pilot, and evaluate city-level strategies to reduce the burden of cardiovascular disease on urban environments and improve quality-of-life.
A new study reveals a significant association between police-related stress and physical markers of cardiovascular health risk in Black women. Women who expressed concern for their children's potential interactions with police had thicker carotid artery walls, indicating increased cardiovascular risk.
Veteran male athletes over 50 are more likely to experience abnormal heart rhythms during training if they have scarring in their hearts. Exercise itself is not the cause, but can act as a trigger for dangerous heart rhythms in those with underlying heart issues.
A new study from UCLA Health found that a cardiovascular risk score can predict who will develop serious eye diseases years later. Higher cardiovascular risk scores were significantly more likely to develop conditions like age-related macular degeneration, diabetic retinopathy, and glaucoma.
A cohort study found that very high lipoprotein(a) levels increased the 30-year risk of cardiovascular disease among healthy women. Screening for elevated lipoprotein(a) may be warranted in the general population.
In a prespecified exploratory analysis of the SELECT randomized clinical trial, semaglutide demonstrated significant reductions in hospital admissions and overall time spent in hospital. This finding suggests that semaglutide has broader health benefits for patients with obesity and established cardiovascular disease.
Gracie Greenlaw, an 11-year-old patient with hypoplastic left heart syndrome, undergoes the world's first pediatric heart and liver dual organ transplant at Children's Hospital Colorado. The groundbreaking procedure, performed by Dr. Megan Adams' team, aims to improve her quality of life by addressing long-term complications from her h...
A novel analysis found that financial strain and food insecurity accelerate biological aging and increase mortality risk, surpassing traditional risk factors. The study emphasizes the need for targeted preventive interventions and patient-centered care to address social determinants of health.
Experts warn that nicotine-containing products, including vapes, heated tobacco, and shisha, cause cardiovascular damage regardless of delivery system. The report highlights a rapid rise in youth addiction fueled by flavours and social media marketing.
A new study published in the Canadian Journal of Cardiology suggests that strong and supportive relationships can improve heart health for individuals with cardiovascular disease. The review highlights the need to include intimate partners in cardiac rehabilitation programs to support long-term heart health and quality of life.
A large study found that a family history of cardiometabolic diseases increases the risk of progressive heart damage in adolescents, with increased glucose levels partly explaining this association. The study suggests that early intervention and healthy lifestyle habits can help prevent premature heart damage in children.
A study found cryopreserved platelets to be a cost-effective option for managing surgical bleeding in cardiac surgery, dominating liquid-stored platelets in this setting. Further investigation is required to assess the economic benefits of cryopreserved platelets in broader populations.
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A genetic variant is likely putting some children with myocarditis at higher risk of developing heart failure. The study found that 34.4% of children with dilated cardiomyopathy had a genetic variant, compared to only 6.3% of control children.
The Society for Cardiovascular Angiography and Interventions (SCAI) reviewed the 2025 Interventional Cardiology Fellowship Match results, noting that nearly all applicants successfully matched but 71 positions remained unfilled. SCAI attributes this to a lack of trainees in the pipeline, citing factors like radiation exposure and burno...
Researchers found that sudden cardiac death (SCD) among colorectal cancer patients decreased overall, but disparities remained based on age, sex, and geographic location. The study highlights the need for tailored heart monitoring and care strategies for cancer patients, particularly in underserved groups.
In-flight cardiac arrest is a rare yet catastrophic event that claims up to 86% of air fatalities. Implementing automated external defibrillators (AEDs) on board could significantly boost survival rates from 6% to up to 70%. The authors recommend standardized CPR protocols training, telemedicine integration, and mandatory AED placement.
A randomized clinical trial shows that semaglutide improves glycemic control and weight outcomes in individuals with schizophrenia. The study suggests using glucagon-like peptide-1 receptor agonists as an early intervention strategy to reduce cardiometabolic risk in this population.
Large language models are revolutionizing cardiovascular imaging by automating the interpretation of quantitative perfusion data in nuclear medicine and cardiac magnetic resonance. They also enable personalized protocol optimization in coronary computed tomography angiography, leveraging federated learning for data privacy.
The Society for Cardiovascular Angiography and Interventions (SCAI) and Cardiovascular Research Technologies (CRT) announce a new collaboration to elevate the field of interventional cardiology through shared education programming, legislative activities, and future research initiatives. The partnership aims to improve patient outcomes...
Researchers have identified a key mechanism behind statin-induced muscle damage, paving the way for new statins with reduced side effects. By understanding how statins interact with muscle proteins, scientists can design safer alternatives that preserve cholesterol-lowering benefits.
Withdrawal of tirzepatide after 36-week treatment led to 25% or greater weight regain in most participants within a year, reversing initial cardiometabolic parameter improvements. Continued obesity treatment is crucial for sustained benefits.
A new study found that current cardiac screening tools are not optimal and fail to identify half the people who are at risk of having a heart attack. The researchers assessed the accuracy of widely used tools, including ASCVD and PREVENT calculators, and found that nearly half of patients would not have been recommended for preventive ...
The ESC Digital & AI Summit showcases innovations like smartphone stethoscopes, voice-detected heart failure, and blood-spot analysis for early cardiovascular disease detection. Virtual training using 3D-printed and virtual hearts enables hands-on learning of complex cardiac procedures.
A new AI-driven app, AortaGPT, aims to improve diagnosis and treatment of heritable thoracic aortic diseases by translating complex genetics concepts into actionable care recommendations. The app can also detect subtle facial features associated with genetic conditions affecting the aorta.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
A new report from Northwestern University offers six practical strategies to improve the doctor-patient bedside encounter in an era dominated by AI. By employing these strategies, clinicians can strengthen patient-physician relationships, combat inequities, and reduce burnout, ultimately leading to better patient outcomes.
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
Researchers analyzed insurance claims data from US health insurers to demonstrate the cardiovascular benefits of semaglutide and tirzepatide. Both GLP-1 drugs provide cardioprotective effects, reducing the risk of stroke and heart attack by 18% and 13%, respectively.
Researchers discovered a threefold reduction in harm among patients with coronary artery stenosis who experience pulmonary embolism. Patients with CAS had lower signs of right ventricular strain, including heart rate and biomarker levels.